What is the best way to travel from St. Louis, MO to Houston?
Looking for a trip? Check and compare all the available Buses and Flights to Houston from St. Louis, MO. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Houston from St. Louis, MO?
You can reach Houston with just £68 by taking a Bus from FlixBus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Greyhound US23h 45m023:45St. Louis, MOGateway Station23:30HoustonHarrisburg Blvd Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 26/06/2026 23:45:00 to Harrisburg Blvd Station, Houston (USA) arriving at 27/06/2026 23:30:00. 50 Economy ticket for £141 per person are available. Travel duration is 23h 45m
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Greyhound US28h 5m001:00St. Louis, MOGateway Station05:05HoustonDowntown Houston0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 26/06/2026 01:00:00 to Downtown Houston, Houston (USA) arriving at 27/06/2026 05:05:00. 50 Economy ticket for £153 per person are available. Travel duration is 28h 5m
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Greyhound US31h 10m009:10St. Louis Lambert AirportSt. Louis Lambert Airport16:20HoustonDowntown Houston0EconomyA Bus from Greyhound US goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 26/06/2026 09:10:00 to Downtown Houston, Houston (USA) arriving at 27/06/2026 16:20:00. 50 Economy ticket for £154 per person are available. Travel duration is 31h 10m
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FlixBus20h 40m016:00St. Louis, MOGateway Station12:40HoustonHarrisburg Blvd Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 26/06/2026 16:00:00 to Harrisburg Blvd Station, Houston (USA) arriving at 27/06/2026 12:40:00. 50 Economy ticket for £234 per person are available. Travel duration is 20h 40m
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Frontier Airlines5h 42m017:06St. Louis Lambert AirportSt. Louis Lambert Airport22:48George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 26/06/2026 17:06:00 to George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) arriving at 26/06/2026 22:48:00. 50 Economy ticket for £211 per person are available. Travel duration is 5h 42m
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Skyscanner2h 17m006:14St. Louis Lambert AirportSt. Louis Lambert Airport08:31George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 26/06/2026 06:14:00 to George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) arriving at 26/06/2026 08:31:00. 50 Economy ticket for £359 per person are available. Travel duration is 2h 17m
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Allegiant Air9h 52m008:37MidAmerica St. Louis AirportMidAmerica St. Louis Airport18:29George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport0EconomyA Flight from Allegiant Air goes from MidAmerica St. Louis Airport, MidAmerica St. Louis Airport (USA) at 26/06/2026 08:37:00 to George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) arriving at 26/06/2026 18:29:00. 50 Economy ticket for £361 per person are available. Travel duration is 9h 52m
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United Airlines6h 7m007:20St. Louis Lambert AirportSt. Louis Lambert Airport13:27George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 26/06/2026 07:20:00 to George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) arriving at 26/06/2026 13:27:00. 50 Economy ticket for £366 per person are available. Travel duration is 6h 7m
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Alaska Airlines11h 14m006:02St. Louis Lambert AirportSt. Louis Lambert Airport17:16George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport0EconomyA Flight from Alaska Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 26/06/2026 06:02:00 to George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) arriving at 26/06/2026 17:16:00. 50 Economy ticket for £606 per person are available. Travel duration is 11h 14m
Cheapest Buses Friday
Cheapest Flights Friday
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Greyhound US28h 5m001:00St. Louis, MOGateway Station05:05HoustonDowntown Houston0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 27/06/2026 01:00:00 to Downtown Houston, Houston (USA) arriving at 28/06/2026 05:05:00. 50 Economy ticket for £76 per person are available. Travel duration is 28h 5m
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Greyhound US25h 35m016:30St. Louis, MOGateway Station18:05HoustonDowntown Houston0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 27/06/2026 16:30:00 to Downtown Houston, Houston (USA) arriving at 28/06/2026 18:05:00. 50 Economy ticket for £76 per person are available. Travel duration is 25h 35m
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Greyhound US21h 30m001:20St. Louis, MOGateway Station22:50HoustonHarrisburg Blvd Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 27/06/2026 01:20:00 to Harrisburg Blvd Station, Houston (USA) arriving at 27/06/2026 22:50:00. 50 Economy ticket for £76 per person are available. Travel duration is 21h 30m
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FlixBus20h 15m016:00St. Louis, MOGateway Station12:15HoustonDowntown Houston0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 27/06/2026 16:00:00 to Downtown Houston, Houston (USA) arriving at 28/06/2026 12:15:00. 50 Economy ticket for £76 per person are available. Travel duration is 20h 15m
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FlixBus20h 40m016:00St. Louis, MOGateway Station12:40HoustonHarrisburg Blvd Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 27/06/2026 16:00:00 to Harrisburg Blvd Station, Houston (USA) arriving at 28/06/2026 12:40:00. 50 Economy ticket for £76 per person are available. Travel duration is 20h 40m
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Frontier Airlines5h 42m017:06St. Louis Lambert AirportSt. Louis Lambert Airport22:48George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 27/06/2026 17:06:00 to George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) arriving at 27/06/2026 22:48:00. 50 Economy ticket for £114 per person are available. Travel duration is 5h 42m
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Frontier Airlines15h 4m019:38St. Louis Lambert AirportSt. Louis Lambert Airport10:42George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 27/06/2026 19:38:00 to George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) arriving at 28/06/2026 10:42:00. 50 Economy ticket for £136 per person are available. Travel duration is 15h 4m
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United Airlines2h 17m006:14St. Louis Lambert AirportSt. Louis Lambert Airport08:31George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 27/06/2026 06:14:00 to George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) arriving at 27/06/2026 08:31:00. 50 Economy ticket for £155 per person are available. Travel duration is 2h 17m
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United Airlines5h 51m006:00St. Louis Lambert AirportSt. Louis Lambert Airport11:51George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 27/06/2026 06:00:00 to George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) arriving at 27/06/2026 11:51:00. 50 Economy ticket for £170 per person are available. Travel duration is 5h 51m
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Allegiant Air10h 22m008:07MidAmerica St. Louis AirportMidAmerica St. Louis Airport18:29George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport0EconomyA Flight from Allegiant Air goes from MidAmerica St. Louis Airport, MidAmerica St. Louis Airport (USA) at 27/06/2026 08:07:00 to George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) arriving at 27/06/2026 18:29:00. 50 Economy ticket for £261 per person are available. Travel duration is 10h 22m
Cheapest Buses Saturday
Cheapest Flights Saturday
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FlixBus20h 15m016:00St. Louis, MOGateway Station12:15HoustonDowntown Houston0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 28/06/2026 16:00:00 to Downtown Houston, Houston (USA) arriving at 29/06/2026 12:15:00. 50 Economy ticket for £68 per person are available. Travel duration is 20h 15m
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FlixBus20h 40m016:00St. Louis, MOGateway Station12:40HoustonHarrisburg Blvd Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 28/06/2026 16:00:00 to Harrisburg Blvd Station, Houston (USA) arriving at 29/06/2026 12:40:00. 50 Economy ticket for £68 per person are available. Travel duration is 20h 40m
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Greyhound US28h 5m001:00St. Louis, MOGateway Station05:05HoustonDowntown Houston0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 28/06/2026 01:00:00 to Downtown Houston, Houston (USA) arriving at 29/06/2026 05:05:00. 50 Economy ticket for £69 per person are available. Travel duration is 28h 5m
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Greyhound US21h 30m001:20St. Louis, MOGateway Station22:50HoustonHarrisburg Blvd Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 28/06/2026 01:20:00 to Harrisburg Blvd Station, Houston (USA) arriving at 28/06/2026 22:50:00. 50 Economy ticket for £69 per person are available. Travel duration is 21h 30m
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Frontier Airlines15h 36m018:31St. Louis Lambert AirportSt. Louis Lambert Airport10:07George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 28/06/2026 18:31:00 to George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) arriving at 29/06/2026 10:07:00. 50 Economy ticket for £116 per person are available. Travel duration is 15h 36m
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Skyscanner2h 17m006:14St. Louis Lambert AirportSt. Louis Lambert Airport08:31George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 28/06/2026 06:14:00 to George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) arriving at 28/06/2026 08:31:00. 50 Economy ticket for £154 per person are available. Travel duration is 2h 17m
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United Airlines2h 17m006:14St. Louis Lambert AirportSt. Louis Lambert Airport08:31George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 28/06/2026 06:14:00 to George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) arriving at 28/06/2026 08:31:00. 50 Economy ticket for £155 per person are available. Travel duration is 2h 17m
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Allegiant Air18h 36m014:11MidAmerica St. Louis AirportMidAmerica St. Louis Airport08:47George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport0EconomyA Flight from Allegiant Air goes from MidAmerica St. Louis Airport, MidAmerica St. Louis Airport (USA) at 28/06/2026 14:11:00 to George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) arriving at 29/06/2026 08:47:00. 50 Economy ticket for £190 per person are available. Travel duration is 18h 36m
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Alaska Airlines10h 24m019:56St. Louis Lambert AirportSt. Louis Lambert Airport06:20George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport0EconomyA Flight from Alaska Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 28/06/2026 19:56:00 to George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) arriving at 29/06/2026 06:20:00. 50 Economy ticket for £376 per person are available. Travel duration is 10h 24m
Cheapest Buses Sunday
Cheapest Flights Sunday
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Greyhound US25h 35m016:30St. Louis, MOGateway Station18:05HoustonDowntown Houston0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 02/07/2026 16:30:00 to Downtown Houston, Houston (USA) arriving at 03/07/2026 18:05:00. 50 Economy ticket for £74 per person are available. Travel duration is 25h 35m
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Greyhound US28h 15m001:00St. Louis, MOGateway Station05:15HoustonDowntown Houston0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 02/07/2026 01:00:00 to Downtown Houston, Houston (USA) arriving at 03/07/2026 05:15:00. 50 Economy ticket for £75 per person are available. Travel duration is 28h 15m
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Greyhound US21h 30m001:20St. Louis, MOGateway Station22:50HoustonHarrisburg Blvd Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 02/07/2026 01:20:00 to Harrisburg Blvd Station, Houston (USA) arriving at 02/07/2026 22:50:00. 50 Economy ticket for £75 per person are available. Travel duration is 21h 30m
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FlixBus21h 45m016:00St. Louis, MOGateway Station13:45HoustonUptown/Upper Kirby0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 02/07/2026 16:00:00 to Uptown/Upper Kirby, Houston (USA) arriving at 03/07/2026 13:45:00. 50 Economy ticket for £75 per person are available. Travel duration is 21h 45m
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FlixBus20h 15m016:00St. Louis, MOGateway Station12:15HoustonDowntown Houston0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 02/07/2026 16:00:00 to Downtown Houston, Houston (USA) arriving at 03/07/2026 12:15:00. 50 Economy ticket for £76 per person are available. Travel duration is 20h 15m
Cheapest Buses Thursday
What are the fastest trips from St. Louis, MO to Houston?
You can get to Houston from St. Louis, MO in just 2h 17m with a Flight from Skyscanner. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Skyscanner2h 17m006:14St. Louis Lambert AirportSt. Louis Lambert Airport08:31George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 26/06/2026 06:14:00 to George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) arriving at 26/06/2026 08:31:00. 50 Economy ticket for £359 per person are available. Travel duration is 2h 17m
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Frontier Airlines5h 42m017:06St. Louis Lambert AirportSt. Louis Lambert Airport22:48George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 26/06/2026 17:06:00 to George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) arriving at 26/06/2026 22:48:00. 50 Economy ticket for £211 per person are available. Travel duration is 5h 42m
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United Airlines6h 7m007:20St. Louis Lambert AirportSt. Louis Lambert Airport13:27George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 26/06/2026 07:20:00 to George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) arriving at 26/06/2026 13:27:00. 50 Economy ticket for £366 per person are available. Travel duration is 6h 7m
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Allegiant Air9h 52m008:37MidAmerica St. Louis AirportMidAmerica St. Louis Airport18:29George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport0EconomyA Flight from Allegiant Air goes from MidAmerica St. Louis Airport, MidAmerica St. Louis Airport (USA) at 26/06/2026 08:37:00 to George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) arriving at 26/06/2026 18:29:00. 50 Economy ticket for £361 per person are available. Travel duration is 9h 52m
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Alaska Airlines11h 14m006:02St. Louis Lambert AirportSt. Louis Lambert Airport17:16George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport0EconomyA Flight from Alaska Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 26/06/2026 06:02:00 to George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) arriving at 26/06/2026 17:16:00. 50 Economy ticket for £606 per person are available. Travel duration is 11h 14m
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FlixBus20h 40m016:00St. Louis, MOGateway Station12:40HoustonHarrisburg Blvd Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 26/06/2026 16:00:00 to Harrisburg Blvd Station, Houston (USA) arriving at 27/06/2026 12:40:00. 50 Economy ticket for £234 per person are available. Travel duration is 20h 40m
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Greyhound US23h 45m023:45St. Louis, MOGateway Station23:30HoustonHarrisburg Blvd Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 26/06/2026 23:45:00 to Harrisburg Blvd Station, Houston (USA) arriving at 27/06/2026 23:30:00. 50 Economy ticket for £141 per person are available. Travel duration is 23h 45m
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Greyhound US28h 5m001:00St. Louis, MOGateway Station05:05HoustonDowntown Houston0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 26/06/2026 01:00:00 to Downtown Houston, Houston (USA) arriving at 27/06/2026 05:05:00. 50 Economy ticket for £153 per person are available. Travel duration is 28h 5m
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Greyhound US31h 10m009:10St. Louis Lambert AirportSt. Louis Lambert Airport16:20HoustonDowntown Houston0EconomyA Bus from Greyhound US goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 26/06/2026 09:10:00 to Downtown Houston, Houston (USA) arriving at 27/06/2026 16:20:00. 50 Economy ticket for £154 per person are available. Travel duration is 31h 10m
Fastest Flights Friday
Fastest Buses Friday
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United Airlines2h 17m006:14St. Louis Lambert AirportSt. Louis Lambert Airport08:31George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 27/06/2026 06:14:00 to George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) arriving at 27/06/2026 08:31:00. 50 Economy ticket for £155 per person are available. Travel duration is 2h 17m
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Frontier Airlines5h 42m017:06St. Louis Lambert AirportSt. Louis Lambert Airport22:48George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 27/06/2026 17:06:00 to George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) arriving at 27/06/2026 22:48:00. 50 Economy ticket for £114 per person are available. Travel duration is 5h 42m
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United Airlines5h 51m006:00St. Louis Lambert AirportSt. Louis Lambert Airport11:51George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 27/06/2026 06:00:00 to George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) arriving at 27/06/2026 11:51:00. 50 Economy ticket for £170 per person are available. Travel duration is 5h 51m
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Allegiant Air10h 22m008:07MidAmerica St. Louis AirportMidAmerica St. Louis Airport18:29George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport0EconomyA Flight from Allegiant Air goes from MidAmerica St. Louis Airport, MidAmerica St. Louis Airport (USA) at 27/06/2026 08:07:00 to George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) arriving at 27/06/2026 18:29:00. 50 Economy ticket for £261 per person are available. Travel duration is 10h 22m
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Frontier Airlines15h 4m019:38St. Louis Lambert AirportSt. Louis Lambert Airport10:42George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 27/06/2026 19:38:00 to George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) arriving at 28/06/2026 10:42:00. 50 Economy ticket for £136 per person are available. Travel duration is 15h 4m
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FlixBus20h 15m016:00St. Louis, MOGateway Station12:15HoustonDowntown Houston0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 27/06/2026 16:00:00 to Downtown Houston, Houston (USA) arriving at 28/06/2026 12:15:00. 50 Economy ticket for £76 per person are available. Travel duration is 20h 15m
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FlixBus20h 40m016:00St. Louis, MOGateway Station12:40HoustonHarrisburg Blvd Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 27/06/2026 16:00:00 to Harrisburg Blvd Station, Houston (USA) arriving at 28/06/2026 12:40:00. 50 Economy ticket for £76 per person are available. Travel duration is 20h 40m
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Greyhound US21h 30m001:20St. Louis, MOGateway Station22:50HoustonHarrisburg Blvd Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 27/06/2026 01:20:00 to Harrisburg Blvd Station, Houston (USA) arriving at 27/06/2026 22:50:00. 50 Economy ticket for £76 per person are available. Travel duration is 21h 30m
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Greyhound US25h 35m016:30St. Louis, MOGateway Station18:05HoustonDowntown Houston0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 27/06/2026 16:30:00 to Downtown Houston, Houston (USA) arriving at 28/06/2026 18:05:00. 50 Economy ticket for £76 per person are available. Travel duration is 25h 35m
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Greyhound US28h 5m001:00St. Louis, MOGateway Station05:05HoustonDowntown Houston0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 27/06/2026 01:00:00 to Downtown Houston, Houston (USA) arriving at 28/06/2026 05:05:00. 50 Economy ticket for £76 per person are available. Travel duration is 28h 5m
Fastest Flights Saturday
Fastest Buses Saturday
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Skyscanner2h 17m006:14St. Louis Lambert AirportSt. Louis Lambert Airport08:31George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 28/06/2026 06:14:00 to George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) arriving at 28/06/2026 08:31:00. 50 Economy ticket for £154 per person are available. Travel duration is 2h 17m
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United Airlines2h 17m006:14St. Louis Lambert AirportSt. Louis Lambert Airport08:31George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 28/06/2026 06:14:00 to George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) arriving at 28/06/2026 08:31:00. 50 Economy ticket for £155 per person are available. Travel duration is 2h 17m
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Alaska Airlines10h 24m019:56St. Louis Lambert AirportSt. Louis Lambert Airport06:20George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport0EconomyA Flight from Alaska Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 28/06/2026 19:56:00 to George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) arriving at 29/06/2026 06:20:00. 50 Economy ticket for £376 per person are available. Travel duration is 10h 24m
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Frontier Airlines15h 36m018:31St. Louis Lambert AirportSt. Louis Lambert Airport10:07George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 28/06/2026 18:31:00 to George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) arriving at 29/06/2026 10:07:00. 50 Economy ticket for £116 per person are available. Travel duration is 15h 36m
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Allegiant Air18h 36m014:11MidAmerica St. Louis AirportMidAmerica St. Louis Airport08:47George Bush Intercontinental Houston AirportGeorge Bush Intercontinental Houston Airport0EconomyA Flight from Allegiant Air goes from MidAmerica St. Louis Airport, MidAmerica St. Louis Airport (USA) at 28/06/2026 14:11:00 to George Bush Intercontinental Houston Airport, George Bush Intercontinental Houston Airport (USA) arriving at 29/06/2026 08:47:00. 50 Economy ticket for £190 per person are available. Travel duration is 18h 36m
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FlixBus20h 15m016:00St. Louis, MOGateway Station12:15HoustonDowntown Houston0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 28/06/2026 16:00:00 to Downtown Houston, Houston (USA) arriving at 29/06/2026 12:15:00. 50 Economy ticket for £68 per person are available. Travel duration is 20h 15m
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FlixBus20h 40m016:00St. Louis, MOGateway Station12:40HoustonHarrisburg Blvd Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 28/06/2026 16:00:00 to Harrisburg Blvd Station, Houston (USA) arriving at 29/06/2026 12:40:00. 50 Economy ticket for £68 per person are available. Travel duration is 20h 40m
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Greyhound US21h 30m001:20St. Louis, MOGateway Station22:50HoustonHarrisburg Blvd Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 28/06/2026 01:20:00 to Harrisburg Blvd Station, Houston (USA) arriving at 28/06/2026 22:50:00. 50 Economy ticket for £69 per person are available. Travel duration is 21h 30m
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Greyhound US28h 5m001:00St. Louis, MOGateway Station05:05HoustonDowntown Houston0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 28/06/2026 01:00:00 to Downtown Houston, Houston (USA) arriving at 29/06/2026 05:05:00. 50 Economy ticket for £69 per person are available. Travel duration is 28h 5m
Fastest Flights Sunday
Fastest Buses Sunday
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FlixBus20h 15m016:00St. Louis, MOGateway Station12:15HoustonDowntown Houston0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 02/07/2026 16:00:00 to Downtown Houston, Houston (USA) arriving at 03/07/2026 12:15:00. 50 Economy ticket for £76 per person are available. Travel duration is 20h 15m
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Greyhound US21h 30m001:20St. Louis, MOGateway Station22:50HoustonHarrisburg Blvd Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 02/07/2026 01:20:00 to Harrisburg Blvd Station, Houston (USA) arriving at 02/07/2026 22:50:00. 50 Economy ticket for £75 per person are available. Travel duration is 21h 30m
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FlixBus21h 45m016:00St. Louis, MOGateway Station13:45HoustonUptown/Upper Kirby0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 02/07/2026 16:00:00 to Uptown/Upper Kirby, Houston (USA) arriving at 03/07/2026 13:45:00. 50 Economy ticket for £75 per person are available. Travel duration is 21h 45m
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Greyhound US25h 35m016:30St. Louis, MOGateway Station18:05HoustonDowntown Houston0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 02/07/2026 16:30:00 to Downtown Houston, Houston (USA) arriving at 03/07/2026 18:05:00. 50 Economy ticket for £74 per person are available. Travel duration is 25h 35m
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Greyhound US28h 15m001:00St. Louis, MOGateway Station05:15HoustonDowntown Houston0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 02/07/2026 01:00:00 to Downtown Houston, Houston (USA) arriving at 03/07/2026 05:15:00. 50 Economy ticket for £75 per person are available. Travel duration is 28h 15m
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Here you will find all operators and timetables for a
Bus from St. Louis, MO to Houston
What are the most popular stations in St. Louis, MO and Houston?
In St. Louis, MO, you will usually depart from Gateway Station, Lindbergh @ Hackberry NB Bus Stop or Skinker Boulevard, while in Houston you will be arriving at Hillcroft METRO Park and Ride Coach Station, Lockwood or Main St & Airline Dr, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Houston from St. Louis, MO? With 8 connections between 2 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between St. Louis, MO and Houston, you can pay as low as £68 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Skyscanner: you will get to Houston in just 2h 17m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting St. Louis, MO and Houston are Greyhound US, FlixBus and Frontier Airlines, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in St. Louis, MO and Houston is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Sauget, IL or to West University Place, TX, and look at flights from St. Louis Lambert Airport, and landing at William P. Hobby Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from St. Louis, MO to Houston?
The most popular companies between St. Louis, MO and Houston, are Greyhound US, FlixBus and Frontier Airlines. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Greyhound US and FlixBus
Airlines: Frontier Airlines, United Airlines, Allegiant Air and 2 more.
All you need to know when you travel from St. Louis, MO to Houston
Check all information on comfort and services on all modes of transports from St. Louis, MO to Houston. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from St. Louis, MO to Houston
How can I reach Houston from St. Louis, MO?
Every day, there are on average 8 connections between Flight and Bus, with which you can get to Houston from St. Louis, MO.
How far is Houston from St. Louis, MO?
The distance between St. Louis, MO and Houston is 1,094.8 km.
What is the most ecofriendly mode of transport between St. Louis, MO and Houston?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 30 kgs of CO2, a train 38 kgs, a car 186 kgs, and a flight 269 kgs.
What is the cheapest mode of transport from St. Louis, MO to Houston?
You can get to Houston with just £68 by taking a Bus from FlixBus.
What is the fastest way to get from St. Louis, MO to Houston?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Houston in just 2h 17m with a Flight from Skyscanner.
More routes to St. Louis, MO and to Houston
Looking for more options? Here you can see the most popular routes to St. Louis, MO and to Houston. Simply click on a connection, and you’ll find all the details about the route!
- Trips to St. Louis, MO
- Atlanta, GA to St. Louis, MO
- Dallas to St. Louis, MO
- Houston to St. Louis, MO
- Mexico City to St. Louis, MO
- Monterrey, NL to St. Louis, MO
- New York to St. Louis, MO
- Trips to Houston
- Aguascalientes to Houston
- Atlanta Airport to Houston
- Atlanta, GA to Houston
- Brownsville, TX to Houston
- Chicago to Houston
- Dallas to Houston
- Durango, DG to Houston
- El Paso, TX to Houston
- Fort Worth to Houston
- Guadalajara, JC to Houston
- Laredo, TX to Houston
- Las Vegas to Houston
- Matamoros to Houston
- McAllen, TX to Houston
- Mexico City to Houston
- Monterrey, NL to Houston
- New Orleans, LA to Houston
- Odessa, TX to Houston
- Reynosa to Houston
- San Antonio, TX to Houston
- San Bernardino, CA to Houston
- San Luis Potosí to Houston
- Santiago de Queretaro to Houston
- Washington, DC to Houston
