What is the best way to travel from St. Louis, MO to Detroit?
Looking for a trip? Check and compare all the available Flights and Buses to Detroit from St. Louis, MO. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Detroit from St. Louis, MO?
You can reach Detroit with just £51 by taking a Bus from Greyhound US, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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FlixBus14h 15m023:30St. Louis, MOGateway Station14:45DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 13/11/2026 23:30:00 to Central Coach Station, Detroit (USA) arriving at 14/11/2026 14:45:00. 50 Economy ticket for £64 per person are available. Travel duration is 14h 15m
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Greyhound US13h 50m002:00St. Louis, MOGateway Station16:50DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 13/11/2026 02:00:00 to Central Coach Station, Detroit (USA) arriving at 13/11/2026 16:50:00. 50 Economy ticket for £66 per person are available. Travel duration is 13h 50m
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FlixBus15h 20m014:30St. Louis, MOGateway Station06:50DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 13/11/2026 14:30:00 to Central Coach Station, Detroit (USA) arriving at 14/11/2026 06:50:00. 50 Economy ticket for £66 per person are available. Travel duration is 15h 20m
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 13/11/2026 08:45:00 to Central Coach Station, Detroit (USA) arriving at 13/11/2026 22:55:00. 50 Economy ticket for £67 per person are available. Travel duration is 13h 10m
Cheapest Buses Friday
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Greyhound US13h 50m002:00St. Louis, MOGateway Station16:50DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 14/11/2026 02:00:00 to Central Coach Station, Detroit (USA) arriving at 14/11/2026 16:50:00. 50 Economy ticket for £54 per person are available. Travel duration is 13h 50m
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 14/11/2026 08:45:00 to Central Coach Station, Detroit (USA) arriving at 14/11/2026 22:55:00. 50 Economy ticket for £54 per person are available. Travel duration is 13h 10m
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FlixBus15h 20m014:30St. Louis, MOGateway Station06:50DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 14/11/2026 14:30:00 to Central Coach Station, Detroit (USA) arriving at 15/11/2026 06:50:00. 50 Economy ticket for £54 per person are available. Travel duration is 15h 20m
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FlixBus14h 15m023:30St. Louis, MOGateway Station14:45DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 14/11/2026 23:30:00 to Central Coach Station, Detroit (USA) arriving at 15/11/2026 14:45:00. 50 Economy ticket for £54 per person are available. Travel duration is 14h 15m
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United Airlines6h 28m006:00St. Louis Lambert AirportSt. Louis Lambert Airport13:28Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 14/11/2026 06:00:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 14/11/2026 13:28:00. 50 Economy ticket for £159 per person are available. Travel duration is 6h 28m
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United Airlines8h 23m006:00St. Louis Lambert AirportSt. Louis Lambert Airport15:23Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 14/11/2026 06:00:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 14/11/2026 15:23:00. 50 Economy ticket for £159 per person are available. Travel duration is 8h 23m
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United Airlines6h 57m007:30St. Louis Lambert AirportSt. Louis Lambert Airport15:27Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 14/11/2026 07:30:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 14/11/2026 15:27:00. 50 Economy ticket for £159 per person are available. Travel duration is 6h 57m
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Frontier Airlines26h 52m019:59St. Louis Lambert AirportSt. Louis Lambert Airport23:51Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 14/11/2026 19:59:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 15/11/2026 23:51:00. 50 Economy ticket for £182 per person are available. Travel duration is 26h 52m
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Frontier Airlines15h 26m016:26St. Louis Lambert AirportSt. Louis Lambert Airport08:52Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 14/11/2026 16:26:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 15/11/2026 08:52:00. 50 Economy ticket for £197 per person are available. Travel duration is 15h 26m
Cheapest Buses Saturday
Cheapest Flights Saturday
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Greyhound US13h 50m002:00St. Louis, MOGateway Station16:50DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 15/11/2026 02:00:00 to Central Coach Station, Detroit (USA) arriving at 15/11/2026 16:50:00. 50 Economy ticket for £60 per person are available. Travel duration is 13h 50m
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 15/11/2026 08:45:00 to Central Coach Station, Detroit (USA) arriving at 15/11/2026 22:55:00. 50 Economy ticket for £60 per person are available. Travel duration is 13h 10m
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FlixBus15h 20m014:30St. Louis, MOGateway Station06:50DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 15/11/2026 14:30:00 to Central Coach Station, Detroit (USA) arriving at 16/11/2026 06:50:00. 50 Economy ticket for £60 per person are available. Travel duration is 15h 20m
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FlixBus14h 15m023:30St. Louis, MOGateway Station14:45DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 15/11/2026 23:30:00 to Central Coach Station, Detroit (USA) arriving at 16/11/2026 14:45:00. 50 Economy ticket for £60 per person are available. Travel duration is 14h 15m
Cheapest Buses Sunday
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Greyhound US13h 50m002:00St. Louis, MOGateway Station16:50DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 17/11/2026 02:00:00 to Central Coach Station, Detroit (USA) arriving at 17/11/2026 16:50:00. 50 Economy ticket for £51 per person are available. Travel duration is 13h 50m
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 17/11/2026 08:45:00 to Central Coach Station, Detroit (USA) arriving at 17/11/2026 22:55:00. 50 Economy ticket for £51 per person are available. Travel duration is 13h 10m
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FlixBus15h 20m014:30St. Louis, MOGateway Station06:50DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 17/11/2026 14:30:00 to Central Coach Station, Detroit (USA) arriving at 18/11/2026 06:50:00. 50 Economy ticket for £51 per person are available. Travel duration is 15h 20m
Cheapest Buses Tuesday
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Greyhound US13h 50m002:00St. Louis, MOGateway Station16:50DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 18/11/2026 02:00:00 to Central Coach Station, Detroit (USA) arriving at 18/11/2026 16:50:00. 50 Economy ticket for £52 per person are available. Travel duration is 13h 50m
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 18/11/2026 08:45:00 to Central Coach Station, Detroit (USA) arriving at 18/11/2026 22:55:00. 50 Economy ticket for £52 per person are available. Travel duration is 13h 10m
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Greyhound US18h 50m014:05St. Louis, MOGateway Station09:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 18/11/2026 14:05:00 to Central Coach Station, Detroit (USA) arriving at 19/11/2026 09:55:00. 50 Economy ticket for £53 per person are available. Travel duration is 18h 50m
Cheapest Buses Wednesday
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Greyhound US13h 50m002:00St. Louis, MOGateway Station16:50DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 19/11/2026 02:00:00 to Central Coach Station, Detroit (USA) arriving at 19/11/2026 16:50:00. 50 Economy ticket for £66 per person are available. Travel duration is 13h 50m
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 19/11/2026 08:45:00 to Central Coach Station, Detroit (USA) arriving at 19/11/2026 22:55:00. 50 Economy ticket for £66 per person are available. Travel duration is 13h 10m
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Greyhound US18h 50m014:05St. Louis, MOGateway Station09:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 19/11/2026 14:05:00 to Central Coach Station, Detroit (USA) arriving at 20/11/2026 09:55:00. 50 Economy ticket for £66 per person are available. Travel duration is 18h 50m
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FlixBus14h 15m023:30St. Louis, MOGateway Station14:45DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 19/11/2026 23:30:00 to Central Coach Station, Detroit (USA) arriving at 20/11/2026 14:45:00. 50 Economy ticket for £66 per person are available. Travel duration is 14h 15m
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Frontier Airlines23h 37m019:24St. Louis Lambert AirportSt. Louis Lambert Airport20:01Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 19/11/2026 19:24:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 20/11/2026 20:01:00. 50 Economy ticket for £136 per person are available. Travel duration is 23h 37m
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United Airlines4h 58m007:30St. Louis Lambert AirportSt. Louis Lambert Airport13:28Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 19/11/2026 07:30:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 19/11/2026 13:28:00. 50 Economy ticket for £138 per person are available. Travel duration is 4h 58m
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United Airlines6h 22m013:08St. Louis Lambert AirportSt. Louis Lambert Airport20:30Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 19/11/2026 13:08:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 19/11/2026 20:30:00. 50 Economy ticket for £138 per person are available. Travel duration is 6h 22m
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Frontier Airlines16h 14m019:24St. Louis Lambert AirportSt. Louis Lambert Airport12:38Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 19/11/2026 19:24:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 20/11/2026 12:38:00. 50 Economy ticket for £160 per person are available. Travel duration is 16h 14m
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Alaska Airlines9h 47m006:00St. Louis Lambert AirportSt. Louis Lambert Airport16:47Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Alaska Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 19/11/2026 06:00:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 19/11/2026 16:47:00. 50 Economy ticket for £441 per person are available. Travel duration is 9h 47m
Cheapest Buses Thursday
Cheapest Flights Thursday
What are the fastest trips from St. Louis, MO to Detroit?
You can get to Detroit from St. Louis, MO in just 4h 58m with a Flight from United Airlines. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 13/11/2026 08:45:00 to Central Coach Station, Detroit (USA) arriving at 13/11/2026 22:55:00. 50 Economy ticket for £67 per person are available. Travel duration is 13h 10m
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Greyhound US13h 50m002:00St. Louis, MOGateway Station16:50DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 13/11/2026 02:00:00 to Central Coach Station, Detroit (USA) arriving at 13/11/2026 16:50:00. 50 Economy ticket for £66 per person are available. Travel duration is 13h 50m
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FlixBus14h 15m023:30St. Louis, MOGateway Station14:45DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 13/11/2026 23:30:00 to Central Coach Station, Detroit (USA) arriving at 14/11/2026 14:45:00. 50 Economy ticket for £64 per person are available. Travel duration is 14h 15m
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FlixBus15h 20m014:30St. Louis, MOGateway Station06:50DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 13/11/2026 14:30:00 to Central Coach Station, Detroit (USA) arriving at 14/11/2026 06:50:00. 50 Economy ticket for £66 per person are available. Travel duration is 15h 20m
Fastest Buses Friday
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United Airlines6h 28m006:00St. Louis Lambert AirportSt. Louis Lambert Airport13:28Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 14/11/2026 06:00:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 14/11/2026 13:28:00. 50 Economy ticket for £159 per person are available. Travel duration is 6h 28m
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United Airlines6h 57m007:30St. Louis Lambert AirportSt. Louis Lambert Airport15:27Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 14/11/2026 07:30:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 14/11/2026 15:27:00. 50 Economy ticket for £159 per person are available. Travel duration is 6h 57m
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United Airlines8h 23m006:00St. Louis Lambert AirportSt. Louis Lambert Airport15:23Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 14/11/2026 06:00:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 14/11/2026 15:23:00. 50 Economy ticket for £159 per person are available. Travel duration is 8h 23m
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Frontier Airlines15h 26m016:26St. Louis Lambert AirportSt. Louis Lambert Airport08:52Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 14/11/2026 16:26:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 15/11/2026 08:52:00. 50 Economy ticket for £197 per person are available. Travel duration is 15h 26m
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Frontier Airlines26h 52m019:59St. Louis Lambert AirportSt. Louis Lambert Airport23:51Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 14/11/2026 19:59:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 15/11/2026 23:51:00. 50 Economy ticket for £182 per person are available. Travel duration is 26h 52m
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 14/11/2026 08:45:00 to Central Coach Station, Detroit (USA) arriving at 14/11/2026 22:55:00. 50 Economy ticket for £54 per person are available. Travel duration is 13h 10m
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Greyhound US13h 50m002:00St. Louis, MOGateway Station16:50DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 14/11/2026 02:00:00 to Central Coach Station, Detroit (USA) arriving at 14/11/2026 16:50:00. 50 Economy ticket for £54 per person are available. Travel duration is 13h 50m
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FlixBus14h 15m023:30St. Louis, MOGateway Station14:45DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 14/11/2026 23:30:00 to Central Coach Station, Detroit (USA) arriving at 15/11/2026 14:45:00. 50 Economy ticket for £54 per person are available. Travel duration is 14h 15m
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FlixBus15h 20m014:30St. Louis, MOGateway Station06:50DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 14/11/2026 14:30:00 to Central Coach Station, Detroit (USA) arriving at 15/11/2026 06:50:00. 50 Economy ticket for £54 per person are available. Travel duration is 15h 20m
Fastest Flights Saturday
Fastest Buses Saturday
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 15/11/2026 08:45:00 to Central Coach Station, Detroit (USA) arriving at 15/11/2026 22:55:00. 50 Economy ticket for £60 per person are available. Travel duration is 13h 10m
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Greyhound US13h 50m002:00St. Louis, MOGateway Station16:50DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 15/11/2026 02:00:00 to Central Coach Station, Detroit (USA) arriving at 15/11/2026 16:50:00. 50 Economy ticket for £60 per person are available. Travel duration is 13h 50m
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FlixBus14h 15m023:30St. Louis, MOGateway Station14:45DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 15/11/2026 23:30:00 to Central Coach Station, Detroit (USA) arriving at 16/11/2026 14:45:00. 50 Economy ticket for £60 per person are available. Travel duration is 14h 15m
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FlixBus15h 20m014:30St. Louis, MOGateway Station06:50DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 15/11/2026 14:30:00 to Central Coach Station, Detroit (USA) arriving at 16/11/2026 06:50:00. 50 Economy ticket for £60 per person are available. Travel duration is 15h 20m
Fastest Buses Sunday
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 17/11/2026 08:45:00 to Central Coach Station, Detroit (USA) arriving at 17/11/2026 22:55:00. 50 Economy ticket for £51 per person are available. Travel duration is 13h 10m
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Greyhound US13h 50m002:00St. Louis, MOGateway Station16:50DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 17/11/2026 02:00:00 to Central Coach Station, Detroit (USA) arriving at 17/11/2026 16:50:00. 50 Economy ticket for £51 per person are available. Travel duration is 13h 50m
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FlixBus15h 20m014:30St. Louis, MOGateway Station06:50DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 17/11/2026 14:30:00 to Central Coach Station, Detroit (USA) arriving at 18/11/2026 06:50:00. 50 Economy ticket for £51 per person are available. Travel duration is 15h 20m
Fastest Buses Tuesday
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 18/11/2026 08:45:00 to Central Coach Station, Detroit (USA) arriving at 18/11/2026 22:55:00. 50 Economy ticket for £52 per person are available. Travel duration is 13h 10m
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Greyhound US13h 50m002:00St. Louis, MOGateway Station16:50DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 18/11/2026 02:00:00 to Central Coach Station, Detroit (USA) arriving at 18/11/2026 16:50:00. 50 Economy ticket for £52 per person are available. Travel duration is 13h 50m
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Greyhound US18h 50m014:05St. Louis, MOGateway Station09:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 18/11/2026 14:05:00 to Central Coach Station, Detroit (USA) arriving at 19/11/2026 09:55:00. 50 Economy ticket for £53 per person are available. Travel duration is 18h 50m
Fastest Buses Wednesday
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United Airlines4h 58m007:30St. Louis Lambert AirportSt. Louis Lambert Airport13:28Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 19/11/2026 07:30:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 19/11/2026 13:28:00. 50 Economy ticket for £138 per person are available. Travel duration is 4h 58m
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United Airlines6h 22m013:08St. Louis Lambert AirportSt. Louis Lambert Airport20:30Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 19/11/2026 13:08:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 19/11/2026 20:30:00. 50 Economy ticket for £138 per person are available. Travel duration is 6h 22m
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Alaska Airlines9h 47m006:00St. Louis Lambert AirportSt. Louis Lambert Airport16:47Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Alaska Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 19/11/2026 06:00:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 19/11/2026 16:47:00. 50 Economy ticket for £441 per person are available. Travel duration is 9h 47m
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Frontier Airlines16h 14m019:24St. Louis Lambert AirportSt. Louis Lambert Airport12:38Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 19/11/2026 19:24:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 20/11/2026 12:38:00. 50 Economy ticket for £160 per person are available. Travel duration is 16h 14m
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Frontier Airlines23h 37m019:24St. Louis Lambert AirportSt. Louis Lambert Airport20:01Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 19/11/2026 19:24:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 20/11/2026 20:01:00. 50 Economy ticket for £136 per person are available. Travel duration is 23h 37m
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 19/11/2026 08:45:00 to Central Coach Station, Detroit (USA) arriving at 19/11/2026 22:55:00. 50 Economy ticket for £66 per person are available. Travel duration is 13h 10m
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Greyhound US13h 50m002:00St. Louis, MOGateway Station16:50DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 19/11/2026 02:00:00 to Central Coach Station, Detroit (USA) arriving at 19/11/2026 16:50:00. 50 Economy ticket for £66 per person are available. Travel duration is 13h 50m
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FlixBus14h 15m023:30St. Louis, MOGateway Station14:45DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 19/11/2026 23:30:00 to Central Coach Station, Detroit (USA) arriving at 20/11/2026 14:45:00. 50 Economy ticket for £66 per person are available. Travel duration is 14h 15m
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Greyhound US18h 50m014:05St. Louis, MOGateway Station09:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 19/11/2026 14:05:00 to Central Coach Station, Detroit (USA) arriving at 20/11/2026 09:55:00. 50 Economy ticket for £66 per person are available. Travel duration is 18h 50m
Fastest Flights Thursday
Fastest Buses Thursday
Here you will find all operators and timetables for a
Bus from St. Louis, MO to Detroit
What are the most popular stations in St. Louis, MO and Detroit?
In St. Louis, MO, you will usually depart from Gateway Station, Lindbergh @ Hackberry NB Bus Stop or Skinker Boulevard, while in Detroit you will be arriving at Central Coach Station, Amtrak or Park Avenue, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Detroit from St. Louis, MO? With 6 connections between 2 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between St. Louis, MO and Detroit, you can pay as low as £51 with a Bus from Greyhound US.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from United Airlines: you will get to Detroit in just 4h 58m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting St. Louis, MO and Detroit are Greyhound US, FlixBus and United Airlines, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in St. Louis, MO and Detroit is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Sauget, IL or to Windsor, ON, and look at flights from St. Louis Lambert Airport, and landing at Detroit Metropolitan Wayne County Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from St. Louis, MO to Detroit?
The most popular companies between St. Louis, MO and Detroit, are Greyhound US, FlixBus and United Airlines. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Greyhound US and FlixBus
Airlines: United Airlines, Frontier Airlines and Alaska Airlines
All you need to know when you travel from St. Louis, MO to Detroit
Check all information on comfort and services on all modes of transports from St. Louis, MO to Detroit. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from St. Louis, MO to Detroit
How can I reach Detroit from St. Louis, MO?
Every day, there are on average 6 connections between Flight and Bus, with which you can get to Detroit from St. Louis, MO.
How far is Detroit from St. Louis, MO?
The distance between St. Louis, MO and Detroit is 731.6 km.
What is the most ecofriendly mode of transport between St. Louis, MO and Detroit?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 20 kgs of CO2, a train 26 kgs, a car 124 kgs, and a flight 180 kgs.
What is the cheapest mode of transport from St. Louis, MO to Detroit?
You can get to Detroit with just £51 by taking a Bus from Greyhound US.
What is the fastest way to get from St. Louis, MO to Detroit?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Detroit in just 4h 58m with a Flight from United Airlines.
More routes to St. Louis, MO and to Detroit
Looking for more options? Here you can see the most popular routes to St. Louis, MO and to Detroit. Simply click on a connection, and you’ll find all the details about the route!
- Trips to St. Louis, MO
- Atlanta, GA to St. Louis, MO
- Houston to St. Louis, MO
- New York to St. Louis, MO
- Trips to Detroit
- Atlanta, GA to Detroit
- Buffalo, NY to Detroit
- Greensboro, NC to Detroit
- Houston to Detroit
- Las Vegas to Detroit
- Los Angeles to Detroit
- Mexico City to Detroit
- Monterrey, NL to Detroit
- Montreal to Detroit
- Nashville to Detroit
- New York to Detroit
- Seattle, WA to Detroit
- Toronto, ON to Detroit
- Washington, DC to Detroit
