What is the best way to travel from St. Louis, MO to Detroit?
Looking for a trip? Check and compare all the available Buses and Flights to Detroit from St. Louis, MO. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Detroit from St. Louis, MO?
You can reach Detroit with just £61 by taking a Bus from Greyhound US, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 13/12/2025 08:45:00 to Central Coach Station, Detroit (USA) arriving at 13/12/2025 22:55:00. 50 Economy ticket for £61 per person are available. Travel duration is 13h 10m
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Greyhound US19h 0m013:55St. Louis, MOGateway Station09:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 13/12/2025 13:55:00 to Central Coach Station, Detroit (USA) arriving at 14/12/2025 09:55:00. 50 Economy ticket for £61 per person are available. Travel duration is 19h 0m
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FlixBus14h 15m023:30St. Louis, MOGateway Station14:45DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 13/12/2025 23:30:00 to Central Coach Station, Detroit (USA) arriving at 14/12/2025 14:45:00. 50 Economy ticket for £61 per person are available. Travel duration is 14h 15m
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FlixBus19h 30m009:30St. Louis, MOGateway Station06:00DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 13/12/2025 09:30:00 to Central Coach Station, Detroit (USA) arriving at 14/12/2025 06:00:00. 50 Economy ticket for £62 per person are available. Travel duration is 19h 30m
Cheapest Buses Saturday
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Frontier Airlines15h 50m015:30St. Louis Lambert AirportSt. Louis Lambert Airport08:20Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 14/12/2025 15:30:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 15/12/2025 08:20:00. 50 Economy ticket for £87 per person are available. Travel duration is 15h 50m
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Spirit Airlines18h 21m014:47St. Louis Lambert AirportSt. Louis Lambert Airport10:08Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Spirit Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 14/12/2025 14:47:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 15/12/2025 10:08:00. 50 Economy ticket for £200 per person are available. Travel duration is 18h 21m
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Skyscanner5h 48m007:00St. Louis Lambert AirportSt. Louis Lambert Airport13:48Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 14/12/2025 07:00:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 14/12/2025 13:48:00. 50 Economy ticket for £349 per person are available. Travel duration is 5h 48m
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United Airlines5h 16m011:50St. Louis Lambert AirportSt. Louis Lambert Airport18:06Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 14/12/2025 11:50:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 14/12/2025 18:06:00. 50 Economy ticket for £349 per person are available. Travel duration is 5h 16m
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Alaska Airlines24h 22m015:23St. Louis Lambert AirportSt. Louis Lambert Airport16:45Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Alaska Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 14/12/2025 15:23:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 15/12/2025 16:45:00. 50 Economy ticket for £487 per person are available. Travel duration is 24h 22m
Cheapest Flights Sunday
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 15/12/2025 08:45:00 to Central Coach Station, Detroit (USA) arriving at 15/12/2025 22:55:00. 50 Economy ticket for £65 per person are available. Travel duration is 13h 10m
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FlixBus15h 15m023:30St. Louis, MOGateway Station15:45DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 15/12/2025 23:30:00 to Central Coach Station, Detroit (USA) arriving at 16/12/2025 15:45:00. 50 Economy ticket for £65 per person are available. Travel duration is 15h 15m
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FlixBus19h 30m009:30St. Louis, MOGateway Station06:00DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 15/12/2025 09:30:00 to Central Coach Station, Detroit (USA) arriving at 16/12/2025 06:00:00. 50 Economy ticket for £66 per person are available. Travel duration is 19h 30m
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Greyhound US19h 0m013:55St. Louis, MOGateway Station09:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 15/12/2025 13:55:00 to Central Coach Station, Detroit (USA) arriving at 16/12/2025 09:55:00. 50 Economy ticket for £76 per person are available. Travel duration is 19h 0m
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Frontier Airlines6h 23m009:54St. Louis Lambert AirportSt. Louis Lambert Airport17:17Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 15/12/2025 09:54:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 15/12/2025 17:17:00. 50 Economy ticket for £99 per person are available. Travel duration is 6h 23m
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Frontier Airlines8h 5m010:47St. Louis Lambert AirportSt. Louis Lambert Airport19:52Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 15/12/2025 10:47:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 15/12/2025 19:52:00. 50 Economy ticket for £199 per person are available. Travel duration is 8h 5m
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Skyscanner5h 48m007:00St. Louis Lambert AirportSt. Louis Lambert Airport13:48Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 15/12/2025 07:00:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 15/12/2025 13:48:00. 50 Economy ticket for £337 per person are available. Travel duration is 5h 48m
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United Airlines5h 16m011:50St. Louis Lambert AirportSt. Louis Lambert Airport18:06Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 15/12/2025 11:50:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 15/12/2025 18:06:00. 50 Economy ticket for £337 per person are available. Travel duration is 5h 16m
Cheapest Buses Monday
Cheapest Flights Monday
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Greyhound US19h 0m013:55St. Louis, MOGateway Station09:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 16/12/2025 13:55:00 to Central Coach Station, Detroit (USA) arriving at 17/12/2025 09:55:00. 50 Economy ticket for £65 per person are available. Travel duration is 19h 0m
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 16/12/2025 08:45:00 to Central Coach Station, Detroit (USA) arriving at 16/12/2025 22:55:00. 50 Economy ticket for £66 per person are available. Travel duration is 13h 10m
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Frontier Airlines15h 37m015:30St. Louis Lambert AirportSt. Louis Lambert Airport08:07Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 16/12/2025 15:30:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 17/12/2025 08:07:00. 50 Economy ticket for £173 per person are available. Travel duration is 15h 37m
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Skyscanner5h 48m007:00St. Louis Lambert AirportSt. Louis Lambert Airport13:48Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 16/12/2025 07:00:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 16/12/2025 13:48:00. 50 Economy ticket for £337 per person are available. Travel duration is 5h 48m
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United Airlines5h 16m011:50St. Louis Lambert AirportSt. Louis Lambert Airport18:06Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 16/12/2025 11:50:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 16/12/2025 18:06:00. 50 Economy ticket for £337 per person are available. Travel duration is 5h 16m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 18/12/2025 08:45:00 to Central Coach Station, Detroit (USA) arriving at 18/12/2025 22:55:00. 50 Economy ticket for £72 per person are available. Travel duration is 13h 10m
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FlixBus19h 30m009:30St. Louis, MOGateway Station06:00DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 18/12/2025 09:30:00 to Central Coach Station, Detroit (USA) arriving at 19/12/2025 06:00:00. 50 Economy ticket for £72 per person are available. Travel duration is 19h 30m
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FlixBus14h 15m023:30St. Louis, MOGateway Station14:45DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 18/12/2025 23:30:00 to Central Coach Station, Detroit (USA) arriving at 19/12/2025 14:45:00. 50 Economy ticket for £72 per person are available. Travel duration is 14h 15m
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Greyhound US19h 0m013:55St. Louis, MOGateway Station09:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 18/12/2025 13:55:00 to Central Coach Station, Detroit (USA) arriving at 19/12/2025 09:55:00. 50 Economy ticket for £73 per person are available. Travel duration is 19h 0m
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Frontier Airlines15h 26m016:27St. Louis Lambert AirportSt. Louis Lambert Airport08:53Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 18/12/2025 16:27:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 19/12/2025 08:53:00. 50 Economy ticket for £84 per person are available. Travel duration is 15h 26m
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Frontier Airlines6h 27m010:42St. Louis Lambert AirportSt. Louis Lambert Airport18:09Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 18/12/2025 10:42:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 18/12/2025 18:09:00. 50 Economy ticket for £99 per person are available. Travel duration is 6h 27m
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Skyscanner5h 45m006:30St. Louis Lambert AirportSt. Louis Lambert Airport13:15Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 18/12/2025 06:30:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 18/12/2025 13:15:00. 50 Economy ticket for £228 per person are available. Travel duration is 5h 45m
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Skyscanner4h 10m008:05St. Louis Lambert AirportSt. Louis Lambert Airport13:15Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 18/12/2025 08:05:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 18/12/2025 13:15:00. 50 Economy ticket for £228 per person are available. Travel duration is 4h 10m
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Spirit Airlines11h 8m011:51St. Louis Lambert AirportSt. Louis Lambert Airport23:59Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Spirit Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 18/12/2025 11:51:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 18/12/2025 23:59:00. 50 Economy ticket for £259 per person are available. Travel duration is 11h 8m
Cheapest Buses Thursday
Cheapest Flights Thursday
What are the fastest trips from St. Louis, MO to Detroit?
You can get to Detroit from St. Louis, MO in just 4h 10m with a Flight from Skyscanner. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 13/12/2025 08:45:00 to Central Coach Station, Detroit (USA) arriving at 13/12/2025 22:55:00. 50 Economy ticket for £61 per person are available. Travel duration is 13h 10m
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FlixBus14h 15m023:30St. Louis, MOGateway Station14:45DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 13/12/2025 23:30:00 to Central Coach Station, Detroit (USA) arriving at 14/12/2025 14:45:00. 50 Economy ticket for £61 per person are available. Travel duration is 14h 15m
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Greyhound US19h 0m013:55St. Louis, MOGateway Station09:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 13/12/2025 13:55:00 to Central Coach Station, Detroit (USA) arriving at 14/12/2025 09:55:00. 50 Economy ticket for £61 per person are available. Travel duration is 19h 0m
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FlixBus19h 30m009:30St. Louis, MOGateway Station06:00DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 13/12/2025 09:30:00 to Central Coach Station, Detroit (USA) arriving at 14/12/2025 06:00:00. 50 Economy ticket for £62 per person are available. Travel duration is 19h 30m
Fastest Buses Saturday
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United Airlines5h 16m011:50St. Louis Lambert AirportSt. Louis Lambert Airport18:06Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 14/12/2025 11:50:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 14/12/2025 18:06:00. 50 Economy ticket for £349 per person are available. Travel duration is 5h 16m
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Skyscanner5h 48m007:00St. Louis Lambert AirportSt. Louis Lambert Airport13:48Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 14/12/2025 07:00:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 14/12/2025 13:48:00. 50 Economy ticket for £349 per person are available. Travel duration is 5h 48m
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Frontier Airlines15h 50m015:30St. Louis Lambert AirportSt. Louis Lambert Airport08:20Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 14/12/2025 15:30:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 15/12/2025 08:20:00. 50 Economy ticket for £87 per person are available. Travel duration is 15h 50m
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Spirit Airlines18h 21m014:47St. Louis Lambert AirportSt. Louis Lambert Airport10:08Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Spirit Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 14/12/2025 14:47:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 15/12/2025 10:08:00. 50 Economy ticket for £200 per person are available. Travel duration is 18h 21m
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Alaska Airlines24h 22m015:23St. Louis Lambert AirportSt. Louis Lambert Airport16:45Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Alaska Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 14/12/2025 15:23:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 15/12/2025 16:45:00. 50 Economy ticket for £487 per person are available. Travel duration is 24h 22m
Fastest Flights Sunday
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United Airlines5h 16m011:50St. Louis Lambert AirportSt. Louis Lambert Airport18:06Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 15/12/2025 11:50:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 15/12/2025 18:06:00. 50 Economy ticket for £337 per person are available. Travel duration is 5h 16m
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Skyscanner5h 48m007:00St. Louis Lambert AirportSt. Louis Lambert Airport13:48Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 15/12/2025 07:00:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 15/12/2025 13:48:00. 50 Economy ticket for £337 per person are available. Travel duration is 5h 48m
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Frontier Airlines6h 23m009:54St. Louis Lambert AirportSt. Louis Lambert Airport17:17Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 15/12/2025 09:54:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 15/12/2025 17:17:00. 50 Economy ticket for £99 per person are available. Travel duration is 6h 23m
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Frontier Airlines8h 5m010:47St. Louis Lambert AirportSt. Louis Lambert Airport19:52Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 15/12/2025 10:47:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 15/12/2025 19:52:00. 50 Economy ticket for £199 per person are available. Travel duration is 8h 5m
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 15/12/2025 08:45:00 to Central Coach Station, Detroit (USA) arriving at 15/12/2025 22:55:00. 50 Economy ticket for £65 per person are available. Travel duration is 13h 10m
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FlixBus15h 15m023:30St. Louis, MOGateway Station15:45DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 15/12/2025 23:30:00 to Central Coach Station, Detroit (USA) arriving at 16/12/2025 15:45:00. 50 Economy ticket for £65 per person are available. Travel duration is 15h 15m
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Greyhound US19h 0m013:55St. Louis, MOGateway Station09:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 15/12/2025 13:55:00 to Central Coach Station, Detroit (USA) arriving at 16/12/2025 09:55:00. 50 Economy ticket for £76 per person are available. Travel duration is 19h 0m
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FlixBus19h 30m009:30St. Louis, MOGateway Station06:00DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 15/12/2025 09:30:00 to Central Coach Station, Detroit (USA) arriving at 16/12/2025 06:00:00. 50 Economy ticket for £66 per person are available. Travel duration is 19h 30m
Fastest Flights Monday
Fastest Buses Monday
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United Airlines5h 16m011:50St. Louis Lambert AirportSt. Louis Lambert Airport18:06Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 16/12/2025 11:50:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 16/12/2025 18:06:00. 50 Economy ticket for £337 per person are available. Travel duration is 5h 16m
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Skyscanner5h 48m007:00St. Louis Lambert AirportSt. Louis Lambert Airport13:48Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 16/12/2025 07:00:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 16/12/2025 13:48:00. 50 Economy ticket for £337 per person are available. Travel duration is 5h 48m
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Frontier Airlines15h 37m015:30St. Louis Lambert AirportSt. Louis Lambert Airport08:07Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 16/12/2025 15:30:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 17/12/2025 08:07:00. 50 Economy ticket for £173 per person are available. Travel duration is 15h 37m
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 16/12/2025 08:45:00 to Central Coach Station, Detroit (USA) arriving at 16/12/2025 22:55:00. 50 Economy ticket for £66 per person are available. Travel duration is 13h 10m
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Greyhound US19h 0m013:55St. Louis, MOGateway Station09:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 16/12/2025 13:55:00 to Central Coach Station, Detroit (USA) arriving at 17/12/2025 09:55:00. 50 Economy ticket for £65 per person are available. Travel duration is 19h 0m
Fastest Flights Tuesday
Fastest Buses Tuesday
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Skyscanner4h 10m008:05St. Louis Lambert AirportSt. Louis Lambert Airport13:15Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 18/12/2025 08:05:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 18/12/2025 13:15:00. 50 Economy ticket for £228 per person are available. Travel duration is 4h 10m
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Skyscanner5h 45m006:30St. Louis Lambert AirportSt. Louis Lambert Airport13:15Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 18/12/2025 06:30:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 18/12/2025 13:15:00. 50 Economy ticket for £228 per person are available. Travel duration is 5h 45m
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Frontier Airlines6h 27m010:42St. Louis Lambert AirportSt. Louis Lambert Airport18:09Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 18/12/2025 10:42:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 18/12/2025 18:09:00. 50 Economy ticket for £99 per person are available. Travel duration is 6h 27m
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Spirit Airlines11h 8m011:51St. Louis Lambert AirportSt. Louis Lambert Airport23:59Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Spirit Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 18/12/2025 11:51:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 18/12/2025 23:59:00. 50 Economy ticket for £259 per person are available. Travel duration is 11h 8m
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Frontier Airlines15h 26m016:27St. Louis Lambert AirportSt. Louis Lambert Airport08:53Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 18/12/2025 16:27:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 19/12/2025 08:53:00. 50 Economy ticket for £84 per person are available. Travel duration is 15h 26m
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 18/12/2025 08:45:00 to Central Coach Station, Detroit (USA) arriving at 18/12/2025 22:55:00. 50 Economy ticket for £72 per person are available. Travel duration is 13h 10m
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FlixBus14h 15m023:30St. Louis, MOGateway Station14:45DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 18/12/2025 23:30:00 to Central Coach Station, Detroit (USA) arriving at 19/12/2025 14:45:00. 50 Economy ticket for £72 per person are available. Travel duration is 14h 15m
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Greyhound US19h 0m013:55St. Louis, MOGateway Station09:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 18/12/2025 13:55:00 to Central Coach Station, Detroit (USA) arriving at 19/12/2025 09:55:00. 50 Economy ticket for £73 per person are available. Travel duration is 19h 0m
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FlixBus19h 30m009:30St. Louis, MOGateway Station06:00DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 18/12/2025 09:30:00 to Central Coach Station, Detroit (USA) arriving at 19/12/2025 06:00:00. 50 Economy ticket for £72 per person are available. Travel duration is 19h 30m
Fastest Flights Thursday
Fastest Buses Thursday
Here you will find all operators and timetables for a
Bus from St. Louis, MO to Detroit
What are the most popular stations in St. Louis, MO and Detroit?
In St. Louis, MO, you will usually depart from Gateway Station, Lindbergh @ Hackberry NB Bus Stop or Skinker Boulevard, while in Detroit you will be arriving at Central Coach Station, Amtrak or Park Avenue, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Detroit from St. Louis, MO? With 7 connections between 2 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between St. Louis, MO and Detroit, you can pay as low as £61 with a Bus from Greyhound US.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Skyscanner: you will get to Detroit in just 4h 10m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting St. Louis, MO and Detroit are Greyhound US, FlixBus and Frontier Airlines, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in St. Louis, MO and Detroit is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Sauget, IL or to Windsor, ON, and look at flights from St. Louis Lambert Airport, and landing at Detroit Metropolitan Wayne County Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from St. Louis, MO to Detroit?
The most popular companies between St. Louis, MO and Detroit, are Greyhound US, FlixBus and Frontier Airlines. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Greyhound US and FlixBus
Airlines: Frontier Airlines, Skyscanner, United Airlines and 2 more.
All you need to know when you travel from St. Louis, MO to Detroit
Check all information on comfort and services on all modes of transports from St. Louis, MO to Detroit. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from St. Louis, MO to Detroit
How can I reach Detroit from St. Louis, MO?
Every day, there are on average 7 connections between Bus and Flight, with which you can get to Detroit from St. Louis, MO.
How far is Detroit from St. Louis, MO?
The distance between St. Louis, MO and Detroit is 731.6 km.
What is the most ecofriendly mode of transport between St. Louis, MO and Detroit?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 20 kgs of CO2, a train 26 kgs, a car 124 kgs, and a flight 180 kgs.
What is the cheapest mode of transport from St. Louis, MO to Detroit?
You can get to Detroit with just £61 by taking a Bus from Greyhound US.
What is the fastest way to get from St. Louis, MO to Detroit?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Detroit in just 4h 10m with a Flight from Skyscanner.
More routes to St. Louis, MO and to Detroit
Looking for more options? Here you can see the most popular routes to St. Louis, MO and to Detroit. Simply click on a connection, and you’ll find all the details about the route!

