What is the best way to travel from St. Louis, MO to Detroit?
Looking for a trip? Check and compare all the available Flights and Buses to Detroit from St. Louis, MO. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Detroit from St. Louis, MO?
You can reach Detroit with just £46 by taking a Bus from Greyhound US, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 28/01/2026 08:45:00 to Central Coach Station, Detroit (USA) arriving at 28/01/2026 22:55:00. 50 Economy ticket for £49 per person are available. Travel duration is 13h 10m
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Greyhound US19h 0m013:55St. Louis, MOGateway Station09:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 28/01/2026 13:55:00 to Central Coach Station, Detroit (USA) arriving at 29/01/2026 09:55:00. 50 Economy ticket for £50 per person are available. Travel duration is 19h 0m
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Frontier Airlines19h 39m017:42St. Louis Lambert AirportSt. Louis Lambert Airport14:21Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 28/01/2026 17:42:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 29/01/2026 14:21:00. 50 Economy ticket for £106 per person are available. Travel duration is 19h 39m
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Frontier Airlines12h 58m020:22St. Louis Lambert AirportSt. Louis Lambert Airport10:20Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 28/01/2026 20:22:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 29/01/2026 10:20:00. 50 Economy ticket for £176 per person are available. Travel duration is 12h 58m
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United Airlines5h 51m006:30St. Louis Lambert AirportSt. Louis Lambert Airport13:21Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 28/01/2026 06:30:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 28/01/2026 13:21:00. 50 Economy ticket for £277 per person are available. Travel duration is 5h 51m
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United Airlines4h 16m008:05St. Louis Lambert AirportSt. Louis Lambert Airport13:21Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 28/01/2026 08:05:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 28/01/2026 13:21:00. 50 Economy ticket for £277 per person are available. Travel duration is 4h 16m
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Skyscanner5h 30m011:22St. Louis Lambert AirportSt. Louis Lambert Airport17:52Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 28/01/2026 11:22:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 28/01/2026 17:52:00. 50 Economy ticket for £327 per person are available. Travel duration is 5h 30m
Cheapest Buses Wednesday
Cheapest Flights Wednesday
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 29/01/2026 08:45:00 to Central Coach Station, Detroit (USA) arriving at 29/01/2026 22:55:00. 50 Economy ticket for £46 per person are available. Travel duration is 13h 10m
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FlixBus14h 15m023:30St. Louis, MOGateway Station14:45DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 29/01/2026 23:30:00 to Central Coach Station, Detroit (USA) arriving at 30/01/2026 14:45:00. 50 Economy ticket for £47 per person are available. Travel duration is 14h 15m
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Greyhound US19h 0m013:55St. Louis, MOGateway Station09:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 29/01/2026 13:55:00 to Central Coach Station, Detroit (USA) arriving at 30/01/2026 09:55:00. 50 Economy ticket for £48 per person are available. Travel duration is 19h 0m
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Frontier Airlines25h 4m017:42St. Louis Lambert AirportSt. Louis Lambert Airport19:46Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 29/01/2026 17:42:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 30/01/2026 19:46:00. 50 Economy ticket for £61 per person are available. Travel duration is 25h 4m
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Frontier Airlines19h 10m017:42St. Louis Lambert AirportSt. Louis Lambert Airport13:52Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 29/01/2026 17:42:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 30/01/2026 13:52:00. 50 Economy ticket for £115 per person are available. Travel duration is 19h 10m
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Frontier Airlines21h 24m017:42St. Louis Lambert AirportSt. Louis Lambert Airport16:06Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 29/01/2026 17:42:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 30/01/2026 16:06:00. 50 Economy ticket for £115 per person are available. Travel duration is 21h 24m
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United Airlines5h 51m006:30St. Louis Lambert AirportSt. Louis Lambert Airport13:21Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 29/01/2026 06:30:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 29/01/2026 13:21:00. 50 Economy ticket for £228 per person are available. Travel duration is 5h 51m
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United Airlines5h 51m007:00St. Louis Lambert AirportSt. Louis Lambert Airport13:51Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 29/01/2026 07:00:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 29/01/2026 13:51:00. 50 Economy ticket for £228 per person are available. Travel duration is 5h 51m
Cheapest Buses Thursday
Cheapest Flights Thursday
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Frontier Airlines12h 58m020:22St. Louis Lambert AirportSt. Louis Lambert Airport10:20Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 31/01/2026 20:22:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 01/02/2026 10:20:00. 50 Economy ticket for £73 per person are available. Travel duration is 12h 58m
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United Airlines5h 41m006:30St. Louis Lambert AirportSt. Louis Lambert Airport13:11Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 31/01/2026 06:30:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 31/01/2026 13:11:00. 50 Economy ticket for £226 per person are available. Travel duration is 5h 41m
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United Airlines4h 6m008:05St. Louis Lambert AirportSt. Louis Lambert Airport13:11Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 31/01/2026 08:05:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 31/01/2026 13:11:00. 50 Economy ticket for £226 per person are available. Travel duration is 4h 6m
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Skyscanner5h 28m011:22St. Louis Lambert AirportSt. Louis Lambert Airport17:50Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 31/01/2026 11:22:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 31/01/2026 17:50:00. 50 Economy ticket for £351 per person are available. Travel duration is 5h 28m
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 31/01/2026 08:45:00 to Central Coach Station, Detroit (USA) arriving at 31/01/2026 22:55:00. 50 Economy ticket for £74 per person are available. Travel duration is 13h 10m
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FlixBus13h 50m016:00St. Louis, MOGateway Station06:50DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 31/01/2026 16:00:00 to Central Coach Station, Detroit (USA) arriving at 01/02/2026 06:50:00. 50 Economy ticket for £74 per person are available. Travel duration is 13h 50m
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FlixBus14h 15m023:30St. Louis, MOGateway Station14:45DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 31/01/2026 23:30:00 to Central Coach Station, Detroit (USA) arriving at 01/02/2026 14:45:00. 50 Economy ticket for £75 per person are available. Travel duration is 14h 15m
Cheapest Flights Saturday
Cheapest Buses Saturday
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FlixBus14h 15m023:30St. Louis, MOGateway Station14:45DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 01/02/2026 23:30:00 to Central Coach Station, Detroit (USA) arriving at 02/02/2026 14:45:00. 50 Economy ticket for £54 per person are available. Travel duration is 14h 15m
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 01/02/2026 08:45:00 to Central Coach Station, Detroit (USA) arriving at 01/02/2026 22:55:00. 50 Economy ticket for £55 per person are available. Travel duration is 13h 10m
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FlixBus13h 50m016:00St. Louis, MOGateway Station06:50DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 01/02/2026 16:00:00 to Central Coach Station, Detroit (USA) arriving at 02/02/2026 06:50:00. 50 Economy ticket for £56 per person are available. Travel duration is 13h 50m
Cheapest Buses Sunday
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 02/02/2026 08:45:00 to Central Coach Station, Detroit (USA) arriving at 02/02/2026 22:55:00. 50 Economy ticket for £46 per person are available. Travel duration is 13h 10m
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FlixBus13h 50m016:00St. Louis, MOGateway Station06:50DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 02/02/2026 16:00:00 to Central Coach Station, Detroit (USA) arriving at 03/02/2026 06:50:00. 50 Economy ticket for £46 per person are available. Travel duration is 13h 50m
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FlixBus15h 15m023:30St. Louis, MOGateway Station15:45DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 02/02/2026 23:30:00 to Central Coach Station, Detroit (USA) arriving at 03/02/2026 15:45:00. 50 Economy ticket for £46 per person are available. Travel duration is 15h 15m
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Frontier Airlines23h 38m010:16St. Louis Lambert AirportSt. Louis Lambert Airport10:54Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 02/02/2026 10:16:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 03/02/2026 10:54:00. 50 Economy ticket for £59 per person are available. Travel duration is 23h 38m
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United Airlines5h 51m006:30St. Louis Lambert AirportSt. Louis Lambert Airport13:21Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 02/02/2026 06:30:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 02/02/2026 13:21:00. 50 Economy ticket for £223 per person are available. Travel duration is 5h 51m
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Skyscanner5h 51m007:00St. Louis Lambert AirportSt. Louis Lambert Airport13:51Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 02/02/2026 07:00:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 02/02/2026 13:51:00. 50 Economy ticket for £324 per person are available. Travel duration is 5h 51m
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Alaska Airlines24h 29m014:50St. Louis Lambert AirportSt. Louis Lambert Airport16:19Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Alaska Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 02/02/2026 14:50:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 03/02/2026 16:19:00. 50 Economy ticket for £431 per person are available. Travel duration is 24h 29m
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Hawaiian Airlines24h 29m014:50St. Louis Lambert AirportSt. Louis Lambert Airport16:19Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Hawaiian Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 02/02/2026 14:50:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 03/02/2026 16:19:00. 50 Economy ticket for £444 per person are available. Travel duration is 24h 29m
Cheapest Buses Monday
Cheapest Flights Monday
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FlixBus13h 50m016:00St. Louis, MOGateway Station06:50DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 03/02/2026 16:00:00 to Central Coach Station, Detroit (USA) arriving at 04/02/2026 06:50:00. 50 Economy ticket for £74 per person are available. Travel duration is 13h 50m
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 03/02/2026 08:45:00 to Central Coach Station, Detroit (USA) arriving at 03/02/2026 22:55:00. 50 Economy ticket for £75 per person are available. Travel duration is 13h 10m
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Frontier Airlines19h 10m017:42St. Louis Lambert AirportSt. Louis Lambert Airport13:52Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 03/02/2026 17:42:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 04/02/2026 13:52:00. 50 Economy ticket for £113 per person are available. Travel duration is 19h 10m
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Frontier Airlines21h 24m017:42St. Louis Lambert AirportSt. Louis Lambert Airport16:06Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 03/02/2026 17:42:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 04/02/2026 16:06:00. 50 Economy ticket for £113 per person are available. Travel duration is 21h 24m
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United Airlines5h 51m006:30St. Louis Lambert AirportSt. Louis Lambert Airport13:21Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 03/02/2026 06:30:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 03/02/2026 13:21:00. 50 Economy ticket for £267 per person are available. Travel duration is 5h 51m
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United Airlines4h 16m008:05St. Louis Lambert AirportSt. Louis Lambert Airport13:21Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 03/02/2026 08:05:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 03/02/2026 13:21:00. 50 Economy ticket for £267 per person are available. Travel duration is 4h 16m
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Alaska Airlines24h 29m014:50St. Louis Lambert AirportSt. Louis Lambert Airport16:19Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Alaska Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 03/02/2026 14:50:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 04/02/2026 16:19:00. 50 Economy ticket for £430 per person are available. Travel duration is 24h 29m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
What are the fastest trips from St. Louis, MO to Detroit?
You can get to Detroit from St. Louis, MO in just 4h 6m with a Flight from United Airlines. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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United Airlines4h 16m008:05St. Louis Lambert AirportSt. Louis Lambert Airport13:21Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 28/01/2026 08:05:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 28/01/2026 13:21:00. 50 Economy ticket for £277 per person are available. Travel duration is 4h 16m
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Skyscanner5h 30m011:22St. Louis Lambert AirportSt. Louis Lambert Airport17:52Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 28/01/2026 11:22:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 28/01/2026 17:52:00. 50 Economy ticket for £327 per person are available. Travel duration is 5h 30m
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United Airlines5h 51m006:30St. Louis Lambert AirportSt. Louis Lambert Airport13:21Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 28/01/2026 06:30:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 28/01/2026 13:21:00. 50 Economy ticket for £277 per person are available. Travel duration is 5h 51m
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Frontier Airlines12h 58m020:22St. Louis Lambert AirportSt. Louis Lambert Airport10:20Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 28/01/2026 20:22:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 29/01/2026 10:20:00. 50 Economy ticket for £176 per person are available. Travel duration is 12h 58m
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Frontier Airlines19h 39m017:42St. Louis Lambert AirportSt. Louis Lambert Airport14:21Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 28/01/2026 17:42:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 29/01/2026 14:21:00. 50 Economy ticket for £106 per person are available. Travel duration is 19h 39m
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 28/01/2026 08:45:00 to Central Coach Station, Detroit (USA) arriving at 28/01/2026 22:55:00. 50 Economy ticket for £49 per person are available. Travel duration is 13h 10m
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Greyhound US19h 0m013:55St. Louis, MOGateway Station09:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 28/01/2026 13:55:00 to Central Coach Station, Detroit (USA) arriving at 29/01/2026 09:55:00. 50 Economy ticket for £50 per person are available. Travel duration is 19h 0m
Fastest Flights Wednesday
Fastest Buses Wednesday
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United Airlines5h 51m006:30St. Louis Lambert AirportSt. Louis Lambert Airport13:21Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 29/01/2026 06:30:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 29/01/2026 13:21:00. 50 Economy ticket for £228 per person are available. Travel duration is 5h 51m
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United Airlines5h 51m007:00St. Louis Lambert AirportSt. Louis Lambert Airport13:51Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 29/01/2026 07:00:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 29/01/2026 13:51:00. 50 Economy ticket for £228 per person are available. Travel duration is 5h 51m
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Frontier Airlines19h 10m017:42St. Louis Lambert AirportSt. Louis Lambert Airport13:52Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 29/01/2026 17:42:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 30/01/2026 13:52:00. 50 Economy ticket for £115 per person are available. Travel duration is 19h 10m
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Frontier Airlines21h 24m017:42St. Louis Lambert AirportSt. Louis Lambert Airport16:06Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 29/01/2026 17:42:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 30/01/2026 16:06:00. 50 Economy ticket for £115 per person are available. Travel duration is 21h 24m
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Frontier Airlines25h 4m017:42St. Louis Lambert AirportSt. Louis Lambert Airport19:46Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 29/01/2026 17:42:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 30/01/2026 19:46:00. 50 Economy ticket for £61 per person are available. Travel duration is 25h 4m
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 29/01/2026 08:45:00 to Central Coach Station, Detroit (USA) arriving at 29/01/2026 22:55:00. 50 Economy ticket for £46 per person are available. Travel duration is 13h 10m
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FlixBus14h 15m023:30St. Louis, MOGateway Station14:45DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 29/01/2026 23:30:00 to Central Coach Station, Detroit (USA) arriving at 30/01/2026 14:45:00. 50 Economy ticket for £47 per person are available. Travel duration is 14h 15m
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Greyhound US19h 0m013:55St. Louis, MOGateway Station09:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 29/01/2026 13:55:00 to Central Coach Station, Detroit (USA) arriving at 30/01/2026 09:55:00. 50 Economy ticket for £48 per person are available. Travel duration is 19h 0m
Fastest Flights Thursday
Fastest Buses Thursday
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United Airlines4h 6m008:05St. Louis Lambert AirportSt. Louis Lambert Airport13:11Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 31/01/2026 08:05:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 31/01/2026 13:11:00. 50 Economy ticket for £226 per person are available. Travel duration is 4h 6m
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Skyscanner5h 28m011:22St. Louis Lambert AirportSt. Louis Lambert Airport17:50Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 31/01/2026 11:22:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 31/01/2026 17:50:00. 50 Economy ticket for £351 per person are available. Travel duration is 5h 28m
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United Airlines5h 41m006:30St. Louis Lambert AirportSt. Louis Lambert Airport13:11Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 31/01/2026 06:30:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 31/01/2026 13:11:00. 50 Economy ticket for £226 per person are available. Travel duration is 5h 41m
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Frontier Airlines12h 58m020:22St. Louis Lambert AirportSt. Louis Lambert Airport10:20Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 31/01/2026 20:22:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 01/02/2026 10:20:00. 50 Economy ticket for £73 per person are available. Travel duration is 12h 58m
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 31/01/2026 08:45:00 to Central Coach Station, Detroit (USA) arriving at 31/01/2026 22:55:00. 50 Economy ticket for £74 per person are available. Travel duration is 13h 10m
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FlixBus13h 50m016:00St. Louis, MOGateway Station06:50DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 31/01/2026 16:00:00 to Central Coach Station, Detroit (USA) arriving at 01/02/2026 06:50:00. 50 Economy ticket for £74 per person are available. Travel duration is 13h 50m
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FlixBus14h 15m023:30St. Louis, MOGateway Station14:45DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 31/01/2026 23:30:00 to Central Coach Station, Detroit (USA) arriving at 01/02/2026 14:45:00. 50 Economy ticket for £75 per person are available. Travel duration is 14h 15m
Fastest Flights Saturday
Fastest Buses Saturday
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 01/02/2026 08:45:00 to Central Coach Station, Detroit (USA) arriving at 01/02/2026 22:55:00. 50 Economy ticket for £55 per person are available. Travel duration is 13h 10m
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FlixBus13h 50m016:00St. Louis, MOGateway Station06:50DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 01/02/2026 16:00:00 to Central Coach Station, Detroit (USA) arriving at 02/02/2026 06:50:00. 50 Economy ticket for £56 per person are available. Travel duration is 13h 50m
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FlixBus14h 15m023:30St. Louis, MOGateway Station14:45DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 01/02/2026 23:30:00 to Central Coach Station, Detroit (USA) arriving at 02/02/2026 14:45:00. 50 Economy ticket for £54 per person are available. Travel duration is 14h 15m
Fastest Buses Sunday
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United Airlines5h 51m006:30St. Louis Lambert AirportSt. Louis Lambert Airport13:21Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 02/02/2026 06:30:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 02/02/2026 13:21:00. 50 Economy ticket for £223 per person are available. Travel duration is 5h 51m
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Skyscanner5h 51m007:00St. Louis Lambert AirportSt. Louis Lambert Airport13:51Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 02/02/2026 07:00:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 02/02/2026 13:51:00. 50 Economy ticket for £324 per person are available. Travel duration is 5h 51m
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Frontier Airlines23h 38m010:16St. Louis Lambert AirportSt. Louis Lambert Airport10:54Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 02/02/2026 10:16:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 03/02/2026 10:54:00. 50 Economy ticket for £59 per person are available. Travel duration is 23h 38m
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Alaska Airlines24h 29m014:50St. Louis Lambert AirportSt. Louis Lambert Airport16:19Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Alaska Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 02/02/2026 14:50:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 03/02/2026 16:19:00. 50 Economy ticket for £431 per person are available. Travel duration is 24h 29m
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Hawaiian Airlines24h 29m014:50St. Louis Lambert AirportSt. Louis Lambert Airport16:19Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Hawaiian Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 02/02/2026 14:50:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 03/02/2026 16:19:00. 50 Economy ticket for £444 per person are available. Travel duration is 24h 29m
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 02/02/2026 08:45:00 to Central Coach Station, Detroit (USA) arriving at 02/02/2026 22:55:00. 50 Economy ticket for £46 per person are available. Travel duration is 13h 10m
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FlixBus13h 50m016:00St. Louis, MOGateway Station06:50DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 02/02/2026 16:00:00 to Central Coach Station, Detroit (USA) arriving at 03/02/2026 06:50:00. 50 Economy ticket for £46 per person are available. Travel duration is 13h 50m
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FlixBus15h 15m023:30St. Louis, MOGateway Station15:45DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 02/02/2026 23:30:00 to Central Coach Station, Detroit (USA) arriving at 03/02/2026 15:45:00. 50 Economy ticket for £46 per person are available. Travel duration is 15h 15m
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United Airlines4h 16m008:05St. Louis Lambert AirportSt. Louis Lambert Airport13:21Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 03/02/2026 08:05:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 03/02/2026 13:21:00. 50 Economy ticket for £267 per person are available. Travel duration is 4h 16m
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United Airlines5h 51m006:30St. Louis Lambert AirportSt. Louis Lambert Airport13:21Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 03/02/2026 06:30:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 03/02/2026 13:21:00. 50 Economy ticket for £267 per person are available. Travel duration is 5h 51m
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Frontier Airlines19h 10m017:42St. Louis Lambert AirportSt. Louis Lambert Airport13:52Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 03/02/2026 17:42:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 04/02/2026 13:52:00. 50 Economy ticket for £113 per person are available. Travel duration is 19h 10m
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Frontier Airlines21h 24m017:42St. Louis Lambert AirportSt. Louis Lambert Airport16:06Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 03/02/2026 17:42:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 04/02/2026 16:06:00. 50 Economy ticket for £113 per person are available. Travel duration is 21h 24m
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Alaska Airlines24h 29m014:50St. Louis Lambert AirportSt. Louis Lambert Airport16:19Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Alaska Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 03/02/2026 14:50:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 04/02/2026 16:19:00. 50 Economy ticket for £430 per person are available. Travel duration is 24h 29m
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 03/02/2026 08:45:00 to Central Coach Station, Detroit (USA) arriving at 03/02/2026 22:55:00. 50 Economy ticket for £75 per person are available. Travel duration is 13h 10m
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FlixBus13h 50m016:00St. Louis, MOGateway Station06:50DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 03/02/2026 16:00:00 to Central Coach Station, Detroit (USA) arriving at 04/02/2026 06:50:00. 50 Economy ticket for £74 per person are available. Travel duration is 13h 50m
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Here you will find all operators and timetables for a
Bus from St. Louis, MO to Detroit
What are the most popular stations in St. Louis, MO and Detroit?
In St. Louis, MO, you will usually depart from Gateway Station, Lindbergh @ Hackberry NB Bus Stop or Skinker Boulevard, while in Detroit you will be arriving at Central Coach Station, Amtrak or Park Avenue, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Detroit from St. Louis, MO? With 8 connections between 2 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between St. Louis, MO and Detroit, you can pay as low as £46 with a Bus from Greyhound US.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from United Airlines: you will get to Detroit in just 4h 6m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting St. Louis, MO and Detroit are Greyhound US, FlixBus and Frontier Airlines, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in St. Louis, MO and Detroit is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Sauget, IL or to Windsor, ON, and look at flights from St. Louis Lambert Airport, and landing at Detroit Metropolitan Wayne County Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from St. Louis, MO to Detroit?
The most popular companies between St. Louis, MO and Detroit, are Greyhound US, FlixBus and Frontier Airlines. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Greyhound US and FlixBus
Airlines: Frontier Airlines, United Airlines, Skyscanner and 2 more.
All you need to know when you travel from St. Louis, MO to Detroit
Check all information on comfort and services on all modes of transports from St. Louis, MO to Detroit. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from St. Louis, MO to Detroit
How can I reach Detroit from St. Louis, MO?
Every day, there are on average 8 connections between Flight and Bus, with which you can get to Detroit from St. Louis, MO.
How far is Detroit from St. Louis, MO?
The distance between St. Louis, MO and Detroit is 731.6 km.
What is the most ecofriendly mode of transport between St. Louis, MO and Detroit?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 20 kgs of CO2, a train 26 kgs, a car 124 kgs, and a flight 180 kgs.
What is the cheapest mode of transport from St. Louis, MO to Detroit?
You can get to Detroit with just £46 by taking a Bus from Greyhound US.
What is the fastest way to get from St. Louis, MO to Detroit?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Detroit in just 4h 6m with a Flight from United Airlines.
More routes to St. Louis, MO and to Detroit
Looking for more options? Here you can see the most popular routes to St. Louis, MO and to Detroit. Simply click on a connection, and you’ll find all the details about the route!
