How to get from St. Louis, MO to Detroit

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What is the best way to travel from St. Louis, MO to Detroit?

Looking for a trip? Check and compare all the available Flights and Buses to Detroit from St. Louis, MO. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
Bus is the cheapest, while Flight is the fastest way on this route
Transport type
Travel time
Cheapest price
Average price
Daily departures
Bus
13h 10m
£45
£54
6
Flight
3h 47m
£128
£316
54

What is the cheapest way to reach Detroit from St. Louis, MO?

You can reach Detroit with just £45 by taking a Bus from Greyhound US, but there are many more cheap offers: we have selected the best ones for you for the next few days here.

Monday
from £48
Tuesday
from £62
Wednesday
from £51
Thursday
from £45
Friday
Saturday
from £52
Sunday
from £61

    Cheapest Buses Monday

  • FlixBus
    13h 50m
    0
    16:00
    St. Louis, MO
    Gateway Station
    06:50
    Detroit
    Central Coach Station
    0
    FlixBus
    Economy
    £48
  • FlixBus
    15h 10m
    0
    23:30
    St. Louis, MO
    Gateway Station
    15:40
    Detroit
    Central Coach Station
    0
    FlixBus
    Economy
    £48
  • Greyhound US
    13h 10m
    0
    08:45
    St. Louis, MO
    Gateway Station
    22:55
    Detroit
    Central Coach Station
    0
    Greyhound US
    Economy
    £49

    Cheapest Buses Tuesday

  • FlixBus
    15h 10m
    0
    23:30
    St. Louis, MO
    Gateway Station
    15:40
    Detroit
    Central Coach Station
    0
    FlixBus
    Economy
    £62
  • Greyhound US
    13h 10m
    0
    08:45
    St. Louis, MO
    Gateway Station
    22:55
    Detroit
    Central Coach Station
    0
    Greyhound US
    Economy
    £63
  • FlixBus
    13h 50m
    0
    16:00
    St. Louis, MO
    Gateway Station
    06:50
    Detroit
    Central Coach Station
    0
    FlixBus
    Economy
    £63
  • Cheapest Flights Tuesday

  • Frontier Airlines
    16h 16m
    0
    16:51
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    10:07
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    Frontier Airlines
    Economy
    from £143
  • Frontier Airlines
    24h 4m
    0
    16:51
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    17:55
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    Frontier Airlines
    Economy
    from £283
  • United Airlines
    5h 46m
    0
    06:25
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    13:11
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    United Airlines
    Economy
    from £298
  • United Airlines
    8h 8m
    0
    07:00
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    16:08
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    United Airlines
    Economy
    from £298
  • Skyscanner
    5h 46m
    0
    06:25
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    13:11
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    Skyscanner
    Economy
    from £299
  • Frontier Airlines
    36h 33m
    0
    06:00
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    19:33
    Windsor International Airport
    Windsor International Airport
    0
    Frontier Airlines
    Economy
    from £728

    Cheapest Buses Wednesday

  • Greyhound US
    13h 10m
    0
    08:45
    St. Louis, MO
    Gateway Station
    22:55
    Detroit
    Central Coach Station
    0
    Greyhound US
    Economy
    £51
  • FlixBus
    14h 15m
    0
    23:30
    St. Louis, MO
    Gateway Station
    14:45
    Detroit
    Central Coach Station
    0
    FlixBus
    Economy
    £51
  • Greyhound US
    19h 0m
    0
    13:55
    St. Louis, MO
    Gateway Station
    09:55
    Detroit
    Central Coach Station
    0
    Greyhound US
    Economy
    £52
  • Cheapest Flights Wednesday

  • Frontier Airlines
    13h 47m
    0
    20:12
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    10:59
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    Frontier Airlines
    Economy
    from £128
  • Frontier Airlines
    10h 47m
    0
    08:32
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    20:19
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    Frontier Airlines
    Economy
    from £151
  • Allegiant Air
    20h 33m
    0
    11:37
    MidAmerica St. Louis Airport
    MidAmerica St. Louis Airport
    09:10
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    Allegiant Air
    Economy
    from £207
  • Allegiant Air
    19h 25m
    0
    11:37
    MidAmerica St. Louis Airport
    MidAmerica St. Louis Airport
    08:02
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    Allegiant Air
    Economy
    from £211
  • United Airlines
    3h 47m
    0
    05:00
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    09:47
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    United Airlines
    Economy
    from £298
  • Delta Air Lines
    12h 1m
    0
    06:32
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    19:33
    Windsor International Airport
    Windsor International Airport
    0
    Delta Air Lines
    Economy
    from £747

    Cheapest Buses Thursday

  • Greyhound US
    13h 10m
    0
    08:45
    St. Louis, MO
    Gateway Station
    22:55
    Detroit
    Central Coach Station
    0
    Greyhound US
    Economy
    £45
  • FlixBus
    14h 15m
    0
    23:30
    St. Louis, MO
    Gateway Station
    14:45
    Detroit
    Central Coach Station
    0
    FlixBus
    Economy
    £45
  • Greyhound US
    19h 0m
    0
    13:55
    St. Louis, MO
    Gateway Station
    09:55
    Detroit
    Central Coach Station
    0
    Greyhound US
    Economy
    £47

    Cheapest Buses Saturday

  • FlixBus
    14h 15m
    0
    23:30
    St. Louis, MO
    Gateway Station
    14:45
    Detroit
    Central Coach Station
    0
    FlixBus
    Economy
    £52
  • Greyhound US
    13h 10m
    0
    08:45
    St. Louis, MO
    Gateway Station
    22:55
    Detroit
    Central Coach Station
    0
    Greyhound US
    Economy
    £54
  • FlixBus
    13h 50m
    0
    16:00
    St. Louis, MO
    Gateway Station
    06:50
    Detroit
    Central Coach Station
    0
    FlixBus
    Economy
    £55

    Cheapest Buses Sunday

  • Greyhound US
    13h 10m
    0
    08:45
    St. Louis, MO
    Gateway Station
    22:55
    Detroit
    Central Coach Station
    0
    Greyhound US
    Economy
    £61
  • FlixBus
    13h 50m
    0
    16:00
    St. Louis, MO
    Gateway Station
    06:50
    Detroit
    Central Coach Station
    0
    FlixBus
    Economy
    £61
  • FlixBus
    14h 15m
    0
    23:30
    St. Louis, MO
    Gateway Station
    14:45
    Detroit
    Central Coach Station
    0
    FlixBus
    Economy
    £61
  • Cheapest Flights Sunday

  • Frontier Airlines
    31h 29m
    0
    20:06
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    04:35
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    Frontier Airlines
    Economy
    from £162
  • Frontier Airlines
    25h 52m
    0
    22:47
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    01:39
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    Frontier Airlines
    Economy
    from £166
  • United Airlines
    5h 46m
    0
    06:25
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    13:11
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    United Airlines
    Economy
    from £176
  • United Airlines
    4h 30m
    0
    07:41
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    13:11
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    United Airlines
    Economy
    from £176
  • Alaska Airlines
    22h 36m
    0
    16:20
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    15:56
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    Alaska Airlines
    Economy
    from £391

What are the fastest trips from St. Louis, MO to Detroit?

You can get to Detroit from St. Louis, MO in just 3h 47m with a Flight from United Airlines. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.

Monday
from 13h 10m
Tuesday
from 5h 46m
Wednesday
from 3h 47m
Thursday
from 13h 10m
Friday
Saturday
from 13h 10m
Sunday
from 4h 30m

    Fastest Buses Monday

  • Greyhound US
    13h 10m
    0
    08:45
    St. Louis, MO
    Gateway Station
    22:55
    Detroit
    Central Coach Station
    0
    Greyhound US
    Economy
    £49
  • FlixBus
    13h 50m
    0
    16:00
    St. Louis, MO
    Gateway Station
    06:50
    Detroit
    Central Coach Station
    0
    FlixBus
    Economy
    £48
  • FlixBus
    15h 10m
    0
    23:30
    St. Louis, MO
    Gateway Station
    15:40
    Detroit
    Central Coach Station
    0
    FlixBus
    Economy
    £48

    Fastest Flights Tuesday

  • United Airlines
    5h 46m
    0
    06:25
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    13:11
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    United Airlines
    Economy
    from £298
  • Skyscanner
    5h 46m
    0
    06:25
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    13:11
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    Skyscanner
    Economy
    from £299
  • United Airlines
    8h 8m
    0
    07:00
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    16:08
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    United Airlines
    Economy
    from £298
  • Frontier Airlines
    16h 16m
    0
    16:51
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    10:07
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    Frontier Airlines
    Economy
    from £143
  • Frontier Airlines
    24h 4m
    0
    16:51
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    17:55
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    Frontier Airlines
    Economy
    from £283
  • Frontier Airlines
    36h 33m
    0
    06:00
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    19:33
    Windsor International Airport
    Windsor International Airport
    0
    Frontier Airlines
    Economy
    from £728
  • Fastest Buses Tuesday

  • Greyhound US
    13h 10m
    0
    08:45
    St. Louis, MO
    Gateway Station
    22:55
    Detroit
    Central Coach Station
    0
    Greyhound US
    Economy
    £63
  • FlixBus
    13h 50m
    0
    16:00
    St. Louis, MO
    Gateway Station
    06:50
    Detroit
    Central Coach Station
    0
    FlixBus
    Economy
    £63
  • FlixBus
    15h 10m
    0
    23:30
    St. Louis, MO
    Gateway Station
    15:40
    Detroit
    Central Coach Station
    0
    FlixBus
    Economy
    £62

    Fastest Flights Wednesday

  • United Airlines
    3h 47m
    0
    05:00
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    09:47
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    United Airlines
    Economy
    from £298
  • Frontier Airlines
    10h 47m
    0
    08:32
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    20:19
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    Frontier Airlines
    Economy
    from £151
  • Delta Air Lines
    12h 1m
    0
    06:32
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    19:33
    Windsor International Airport
    Windsor International Airport
    0
    Delta Air Lines
    Economy
    from £747
  • Frontier Airlines
    13h 47m
    0
    20:12
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    10:59
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    Frontier Airlines
    Economy
    from £128
  • Allegiant Air
    19h 25m
    0
    11:37
    MidAmerica St. Louis Airport
    MidAmerica St. Louis Airport
    08:02
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    Allegiant Air
    Economy
    from £211
  • Allegiant Air
    20h 33m
    0
    11:37
    MidAmerica St. Louis Airport
    MidAmerica St. Louis Airport
    09:10
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    Allegiant Air
    Economy
    from £207
  • Fastest Buses Wednesday

  • Greyhound US
    13h 10m
    0
    08:45
    St. Louis, MO
    Gateway Station
    22:55
    Detroit
    Central Coach Station
    0
    Greyhound US
    Economy
    £51
  • FlixBus
    14h 15m
    0
    23:30
    St. Louis, MO
    Gateway Station
    14:45
    Detroit
    Central Coach Station
    0
    FlixBus
    Economy
    £51
  • Greyhound US
    19h 0m
    0
    13:55
    St. Louis, MO
    Gateway Station
    09:55
    Detroit
    Central Coach Station
    0
    Greyhound US
    Economy
    £52

    Fastest Buses Thursday

  • Greyhound US
    13h 10m
    0
    08:45
    St. Louis, MO
    Gateway Station
    22:55
    Detroit
    Central Coach Station
    0
    Greyhound US
    Economy
    £45
  • FlixBus
    14h 15m
    0
    23:30
    St. Louis, MO
    Gateway Station
    14:45
    Detroit
    Central Coach Station
    0
    FlixBus
    Economy
    £45
  • Greyhound US
    19h 0m
    0
    13:55
    St. Louis, MO
    Gateway Station
    09:55
    Detroit
    Central Coach Station
    0
    Greyhound US
    Economy
    £47

    Fastest Buses Saturday

  • Greyhound US
    13h 10m
    0
    08:45
    St. Louis, MO
    Gateway Station
    22:55
    Detroit
    Central Coach Station
    0
    Greyhound US
    Economy
    £54
  • FlixBus
    13h 50m
    0
    16:00
    St. Louis, MO
    Gateway Station
    06:50
    Detroit
    Central Coach Station
    0
    FlixBus
    Economy
    £55
  • FlixBus
    14h 15m
    0
    23:30
    St. Louis, MO
    Gateway Station
    14:45
    Detroit
    Central Coach Station
    0
    FlixBus
    Economy
    £52

    Fastest Flights Sunday

  • United Airlines
    4h 30m
    0
    07:41
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    13:11
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    United Airlines
    Economy
    from £176
  • United Airlines
    5h 46m
    0
    06:25
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    13:11
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    United Airlines
    Economy
    from £176
  • Alaska Airlines
    22h 36m
    0
    16:20
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    15:56
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    Alaska Airlines
    Economy
    from £391
  • Frontier Airlines
    25h 52m
    0
    22:47
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    01:39
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    Frontier Airlines
    Economy
    from £166
  • Frontier Airlines
    31h 29m
    0
    20:06
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    04:35
    Detroit Metropolitan Wayne County Airport
    Detroit Metropolitan Wayne County Airport
    0
    Frontier Airlines
    Economy
    from £162
  • Fastest Buses Sunday

  • Greyhound US
    13h 10m
    0
    08:45
    St. Louis, MO
    Gateway Station
    22:55
    Detroit
    Central Coach Station
    0
    Greyhound US
    Economy
    £61
  • FlixBus
    13h 50m
    0
    16:00
    St. Louis, MO
    Gateway Station
    06:50
    Detroit
    Central Coach Station
    0
    FlixBus
    Economy
    £61
  • FlixBus
    14h 15m
    0
    23:30
    St. Louis, MO
    Gateway Station
    14:45
    Detroit
    Central Coach Station
    0
    FlixBus
    Economy
    £61
Here you will find all operators and timetables for a Bus from St. Louis, MO to Detroit

What are the most popular stations in St. Louis, MO and Detroit?

In St. Louis, MO, you will usually depart from Gateway Station, Lindbergh @ Hackberry NB Bus Stop or Skinker Boulevard, while in Detroit you will be arriving at Central Coach Station, Amtrak or Park Avenue, but there are many more stops to explore in both locations.

How do I decide? Some tips and tricks from our experience

Are you having trouble deciding on how to get to Detroit from St. Louis, MO? With 7 connections between 2 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.

Look for the lowest price

Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between St. Louis, MO and Detroit, you can pay as low as £45 with a Bus from Greyhound US.

Travel duration

Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from United Airlines: you will get to Detroit in just 3h 47m.

Comfort makes all the difference

You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting St. Louis, MO and Detroit are FlixBus, Greyhound US and Frontier Airlines, but be sure to check what they have to offer!

Save money with deals, and always compare

One last tip? Even if you live in St. Louis, MO and Detroit is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Sauget, IL or to Windsor, ON, and look at flights from St. Louis Lambert Airport, and landing at Detroit Metropolitan Wayne County Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!

Which companies offer a trip from St. Louis, MO to Detroit?

The most popular companies between St. Louis, MO and Detroit, are FlixBus, Greyhound US and Frontier Airlines. Be sure to check their seat class offers and the amenities that they provide.

Bus companies: FlixBus and Greyhound US

Airlines: Frontier Airlines, United Airlines, Allegiant Air and 3 more.

All you need to know when you travel from St. Louis, MO to Detroit

Check all information on comfort and services on all modes of transports from St. Louis, MO to Detroit. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.

FAQs about the trip from St. Louis, MO to Detroit

How can I reach Detroit from St. Louis, MO?

Every day, there are on average 7 connections between Flight and Bus, with which you can get to Detroit from St. Louis, MO.

How far is Detroit from St. Louis, MO?

The distance between St. Louis, MO and Detroit is 731.6 km.

What is the most ecofriendly mode of transport between St. Louis, MO and Detroit?

Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance. On this particular route, a bus will emit, per person, a total of 20 kgs of CO2, a train 26 kgs, a car 124 kgs, and a flight 180 kgs.

What is the cheapest mode of transport from St. Louis, MO to Detroit?

You can get to Detroit with just £45 by taking a Bus from Greyhound US.

What is the fastest way to get from St. Louis, MO to Detroit?

While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Detroit in just 3h 47m with a Flight from United Airlines.

More routes to St. Louis, MO and to Detroit

Looking for more options? Here you can see the most popular routes to St. Louis, MO and to Detroit. Simply click on a connection, and you’ll find all the details about the route!

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