What is the best way to travel from St. Louis, MO to Detroit?
Looking for a trip? Check and compare all the available Flights and Buses to Detroit from St. Louis, MO. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Detroit from St. Louis, MO?
You can reach Detroit with just £45 by taking a Bus from Greyhound US, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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FlixBus13h 50m016:00St. Louis, MOGateway Station06:50DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 16/03/2026 16:00:00 to Central Coach Station, Detroit (USA) arriving at 17/03/2026 06:50:00. 50 Economy ticket for £48 per person are available. Travel duration is 13h 50m
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FlixBus15h 10m023:30St. Louis, MOGateway Station15:40DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 16/03/2026 23:30:00 to Central Coach Station, Detroit (USA) arriving at 17/03/2026 15:40:00. 50 Economy ticket for £48 per person are available. Travel duration is 15h 10m
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 16/03/2026 08:45:00 to Central Coach Station, Detroit (USA) arriving at 16/03/2026 22:55:00. 50 Economy ticket for £49 per person are available. Travel duration is 13h 10m
Cheapest Buses Monday
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FlixBus15h 10m023:30St. Louis, MOGateway Station15:40DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 17/03/2026 23:30:00 to Central Coach Station, Detroit (USA) arriving at 18/03/2026 15:40:00. 50 Economy ticket for £62 per person are available. Travel duration is 15h 10m
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 17/03/2026 08:45:00 to Central Coach Station, Detroit (USA) arriving at 17/03/2026 22:55:00. 50 Economy ticket for £63 per person are available. Travel duration is 13h 10m
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FlixBus13h 50m016:00St. Louis, MOGateway Station06:50DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 17/03/2026 16:00:00 to Central Coach Station, Detroit (USA) arriving at 18/03/2026 06:50:00. 50 Economy ticket for £63 per person are available. Travel duration is 13h 50m
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Frontier Airlines16h 16m016:51St. Louis Lambert AirportSt. Louis Lambert Airport10:07Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 17/03/2026 16:51:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 18/03/2026 10:07:00. 50 Economy ticket for £143 per person are available. Travel duration is 16h 16m
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Frontier Airlines24h 4m016:51St. Louis Lambert AirportSt. Louis Lambert Airport17:55Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 17/03/2026 16:51:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 18/03/2026 17:55:00. 50 Economy ticket for £283 per person are available. Travel duration is 24h 4m
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United Airlines5h 46m006:25St. Louis Lambert AirportSt. Louis Lambert Airport13:11Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 17/03/2026 06:25:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 17/03/2026 13:11:00. 50 Economy ticket for £298 per person are available. Travel duration is 5h 46m
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United Airlines8h 8m007:00St. Louis Lambert AirportSt. Louis Lambert Airport16:08Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 17/03/2026 07:00:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 17/03/2026 16:08:00. 50 Economy ticket for £298 per person are available. Travel duration is 8h 8m
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Skyscanner5h 46m006:25St. Louis Lambert AirportSt. Louis Lambert Airport13:11Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 17/03/2026 06:25:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 17/03/2026 13:11:00. 50 Economy ticket for £299 per person are available. Travel duration is 5h 46m
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Frontier Airlines36h 33m006:00St. Louis Lambert AirportSt. Louis Lambert Airport19:33Windsor International AirportWindsor International Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 17/03/2026 06:00:00 to Windsor International Airport, Windsor International Airport (Canada) arriving at 18/03/2026 19:33:00. 50 Economy ticket for £728 per person are available. Travel duration is 36h 33m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 18/03/2026 08:45:00 to Central Coach Station, Detroit (USA) arriving at 18/03/2026 22:55:00. 50 Economy ticket for £51 per person are available. Travel duration is 13h 10m
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FlixBus14h 15m023:30St. Louis, MOGateway Station14:45DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 18/03/2026 23:30:00 to Central Coach Station, Detroit (USA) arriving at 19/03/2026 14:45:00. 50 Economy ticket for £51 per person are available. Travel duration is 14h 15m
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Greyhound US19h 0m013:55St. Louis, MOGateway Station09:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 18/03/2026 13:55:00 to Central Coach Station, Detroit (USA) arriving at 19/03/2026 09:55:00. 50 Economy ticket for £52 per person are available. Travel duration is 19h 0m
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Frontier Airlines13h 47m020:12St. Louis Lambert AirportSt. Louis Lambert Airport10:59Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 18/03/2026 20:12:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 19/03/2026 10:59:00. 50 Economy ticket for £128 per person are available. Travel duration is 13h 47m
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Frontier Airlines10h 47m008:32St. Louis Lambert AirportSt. Louis Lambert Airport20:19Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 18/03/2026 08:32:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 18/03/2026 20:19:00. 50 Economy ticket for £151 per person are available. Travel duration is 10h 47m
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Allegiant Air20h 33m011:37MidAmerica St. Louis AirportMidAmerica St. Louis Airport09:10Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Allegiant Air goes from MidAmerica St. Louis Airport, MidAmerica St. Louis Airport (USA) at 18/03/2026 11:37:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 19/03/2026 09:10:00. 50 Economy ticket for £207 per person are available. Travel duration is 20h 33m
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Allegiant Air19h 25m011:37MidAmerica St. Louis AirportMidAmerica St. Louis Airport08:02Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Allegiant Air goes from MidAmerica St. Louis Airport, MidAmerica St. Louis Airport (USA) at 18/03/2026 11:37:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 19/03/2026 08:02:00. 50 Economy ticket for £211 per person are available. Travel duration is 19h 25m
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United Airlines3h 47m005:00St. Louis Lambert AirportSt. Louis Lambert Airport09:47Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 18/03/2026 05:00:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 18/03/2026 09:47:00. 50 Economy ticket for £298 per person are available. Travel duration is 3h 47m
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Delta Air Lines12h 1m006:32St. Louis Lambert AirportSt. Louis Lambert Airport19:33Windsor International AirportWindsor International Airport0EconomyA Flight from Delta Air Lines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 18/03/2026 06:32:00 to Windsor International Airport, Windsor International Airport (Canada) arriving at 18/03/2026 19:33:00. 50 Economy ticket for £747 per person are available. Travel duration is 12h 1m
Cheapest Buses Wednesday
Cheapest Flights Wednesday
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 19/03/2026 08:45:00 to Central Coach Station, Detroit (USA) arriving at 19/03/2026 22:55:00. 50 Economy ticket for £45 per person are available. Travel duration is 13h 10m
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FlixBus14h 15m023:30St. Louis, MOGateway Station14:45DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 19/03/2026 23:30:00 to Central Coach Station, Detroit (USA) arriving at 20/03/2026 14:45:00. 50 Economy ticket for £45 per person are available. Travel duration is 14h 15m
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Greyhound US19h 0m013:55St. Louis, MOGateway Station09:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 19/03/2026 13:55:00 to Central Coach Station, Detroit (USA) arriving at 20/03/2026 09:55:00. 50 Economy ticket for £47 per person are available. Travel duration is 19h 0m
Cheapest Buses Thursday
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FlixBus14h 15m023:30St. Louis, MOGateway Station14:45DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 21/03/2026 23:30:00 to Central Coach Station, Detroit (USA) arriving at 22/03/2026 14:45:00. 50 Economy ticket for £52 per person are available. Travel duration is 14h 15m
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 21/03/2026 08:45:00 to Central Coach Station, Detroit (USA) arriving at 21/03/2026 22:55:00. 50 Economy ticket for £54 per person are available. Travel duration is 13h 10m
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FlixBus13h 50m016:00St. Louis, MOGateway Station06:50DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 21/03/2026 16:00:00 to Central Coach Station, Detroit (USA) arriving at 22/03/2026 06:50:00. 50 Economy ticket for £55 per person are available. Travel duration is 13h 50m
Cheapest Buses Saturday
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 22/03/2026 08:45:00 to Central Coach Station, Detroit (USA) arriving at 22/03/2026 22:55:00. 50 Economy ticket for £61 per person are available. Travel duration is 13h 10m
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FlixBus13h 50m016:00St. Louis, MOGateway Station06:50DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 22/03/2026 16:00:00 to Central Coach Station, Detroit (USA) arriving at 23/03/2026 06:50:00. 50 Economy ticket for £61 per person are available. Travel duration is 13h 50m
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FlixBus14h 15m023:30St. Louis, MOGateway Station14:45DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 22/03/2026 23:30:00 to Central Coach Station, Detroit (USA) arriving at 23/03/2026 14:45:00. 50 Economy ticket for £61 per person are available. Travel duration is 14h 15m
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Frontier Airlines31h 29m020:06St. Louis Lambert AirportSt. Louis Lambert Airport04:35Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 22/03/2026 20:06:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 24/03/2026 04:35:00. 50 Economy ticket for £162 per person are available. Travel duration is 31h 29m
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Frontier Airlines25h 52m022:47St. Louis Lambert AirportSt. Louis Lambert Airport01:39Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 22/03/2026 22:47:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 24/03/2026 01:39:00. 50 Economy ticket for £166 per person are available. Travel duration is 25h 52m
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United Airlines5h 46m006:25St. Louis Lambert AirportSt. Louis Lambert Airport13:11Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 22/03/2026 06:25:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 22/03/2026 13:11:00. 50 Economy ticket for £176 per person are available. Travel duration is 5h 46m
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United Airlines4h 30m007:41St. Louis Lambert AirportSt. Louis Lambert Airport13:11Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 22/03/2026 07:41:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 22/03/2026 13:11:00. 50 Economy ticket for £176 per person are available. Travel duration is 4h 30m
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Alaska Airlines22h 36m016:20St. Louis Lambert AirportSt. Louis Lambert Airport15:56Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Alaska Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 22/03/2026 16:20:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 23/03/2026 15:56:00. 50 Economy ticket for £391 per person are available. Travel duration is 22h 36m
Cheapest Buses Sunday
Cheapest Flights Sunday
What are the fastest trips from St. Louis, MO to Detroit?
You can get to Detroit from St. Louis, MO in just 3h 47m with a Flight from United Airlines. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 16/03/2026 08:45:00 to Central Coach Station, Detroit (USA) arriving at 16/03/2026 22:55:00. 50 Economy ticket for £49 per person are available. Travel duration is 13h 10m
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FlixBus13h 50m016:00St. Louis, MOGateway Station06:50DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 16/03/2026 16:00:00 to Central Coach Station, Detroit (USA) arriving at 17/03/2026 06:50:00. 50 Economy ticket for £48 per person are available. Travel duration is 13h 50m
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FlixBus15h 10m023:30St. Louis, MOGateway Station15:40DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 16/03/2026 23:30:00 to Central Coach Station, Detroit (USA) arriving at 17/03/2026 15:40:00. 50 Economy ticket for £48 per person are available. Travel duration is 15h 10m
Fastest Buses Monday
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United Airlines5h 46m006:25St. Louis Lambert AirportSt. Louis Lambert Airport13:11Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 17/03/2026 06:25:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 17/03/2026 13:11:00. 50 Economy ticket for £298 per person are available. Travel duration is 5h 46m
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Skyscanner5h 46m006:25St. Louis Lambert AirportSt. Louis Lambert Airport13:11Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 17/03/2026 06:25:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 17/03/2026 13:11:00. 50 Economy ticket for £299 per person are available. Travel duration is 5h 46m
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United Airlines8h 8m007:00St. Louis Lambert AirportSt. Louis Lambert Airport16:08Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 17/03/2026 07:00:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 17/03/2026 16:08:00. 50 Economy ticket for £298 per person are available. Travel duration is 8h 8m
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Frontier Airlines16h 16m016:51St. Louis Lambert AirportSt. Louis Lambert Airport10:07Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 17/03/2026 16:51:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 18/03/2026 10:07:00. 50 Economy ticket for £143 per person are available. Travel duration is 16h 16m
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Frontier Airlines24h 4m016:51St. Louis Lambert AirportSt. Louis Lambert Airport17:55Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 17/03/2026 16:51:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 18/03/2026 17:55:00. 50 Economy ticket for £283 per person are available. Travel duration is 24h 4m
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Frontier Airlines36h 33m006:00St. Louis Lambert AirportSt. Louis Lambert Airport19:33Windsor International AirportWindsor International Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 17/03/2026 06:00:00 to Windsor International Airport, Windsor International Airport (Canada) arriving at 18/03/2026 19:33:00. 50 Economy ticket for £728 per person are available. Travel duration is 36h 33m
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 17/03/2026 08:45:00 to Central Coach Station, Detroit (USA) arriving at 17/03/2026 22:55:00. 50 Economy ticket for £63 per person are available. Travel duration is 13h 10m
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FlixBus13h 50m016:00St. Louis, MOGateway Station06:50DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 17/03/2026 16:00:00 to Central Coach Station, Detroit (USA) arriving at 18/03/2026 06:50:00. 50 Economy ticket for £63 per person are available. Travel duration is 13h 50m
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FlixBus15h 10m023:30St. Louis, MOGateway Station15:40DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 17/03/2026 23:30:00 to Central Coach Station, Detroit (USA) arriving at 18/03/2026 15:40:00. 50 Economy ticket for £62 per person are available. Travel duration is 15h 10m
Fastest Flights Tuesday
Fastest Buses Tuesday
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United Airlines3h 47m005:00St. Louis Lambert AirportSt. Louis Lambert Airport09:47Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 18/03/2026 05:00:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 18/03/2026 09:47:00. 50 Economy ticket for £298 per person are available. Travel duration is 3h 47m
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Frontier Airlines10h 47m008:32St. Louis Lambert AirportSt. Louis Lambert Airport20:19Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 18/03/2026 08:32:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 18/03/2026 20:19:00. 50 Economy ticket for £151 per person are available. Travel duration is 10h 47m
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Delta Air Lines12h 1m006:32St. Louis Lambert AirportSt. Louis Lambert Airport19:33Windsor International AirportWindsor International Airport0EconomyA Flight from Delta Air Lines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 18/03/2026 06:32:00 to Windsor International Airport, Windsor International Airport (Canada) arriving at 18/03/2026 19:33:00. 50 Economy ticket for £747 per person are available. Travel duration is 12h 1m
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Frontier Airlines13h 47m020:12St. Louis Lambert AirportSt. Louis Lambert Airport10:59Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 18/03/2026 20:12:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 19/03/2026 10:59:00. 50 Economy ticket for £128 per person are available. Travel duration is 13h 47m
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Allegiant Air19h 25m011:37MidAmerica St. Louis AirportMidAmerica St. Louis Airport08:02Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Allegiant Air goes from MidAmerica St. Louis Airport, MidAmerica St. Louis Airport (USA) at 18/03/2026 11:37:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 19/03/2026 08:02:00. 50 Economy ticket for £211 per person are available. Travel duration is 19h 25m
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Allegiant Air20h 33m011:37MidAmerica St. Louis AirportMidAmerica St. Louis Airport09:10Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Allegiant Air goes from MidAmerica St. Louis Airport, MidAmerica St. Louis Airport (USA) at 18/03/2026 11:37:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 19/03/2026 09:10:00. 50 Economy ticket for £207 per person are available. Travel duration is 20h 33m
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 18/03/2026 08:45:00 to Central Coach Station, Detroit (USA) arriving at 18/03/2026 22:55:00. 50 Economy ticket for £51 per person are available. Travel duration is 13h 10m
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FlixBus14h 15m023:30St. Louis, MOGateway Station14:45DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 18/03/2026 23:30:00 to Central Coach Station, Detroit (USA) arriving at 19/03/2026 14:45:00. 50 Economy ticket for £51 per person are available. Travel duration is 14h 15m
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Greyhound US19h 0m013:55St. Louis, MOGateway Station09:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 18/03/2026 13:55:00 to Central Coach Station, Detroit (USA) arriving at 19/03/2026 09:55:00. 50 Economy ticket for £52 per person are available. Travel duration is 19h 0m
Fastest Flights Wednesday
Fastest Buses Wednesday
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 19/03/2026 08:45:00 to Central Coach Station, Detroit (USA) arriving at 19/03/2026 22:55:00. 50 Economy ticket for £45 per person are available. Travel duration is 13h 10m
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FlixBus14h 15m023:30St. Louis, MOGateway Station14:45DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 19/03/2026 23:30:00 to Central Coach Station, Detroit (USA) arriving at 20/03/2026 14:45:00. 50 Economy ticket for £45 per person are available. Travel duration is 14h 15m
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Greyhound US19h 0m013:55St. Louis, MOGateway Station09:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 19/03/2026 13:55:00 to Central Coach Station, Detroit (USA) arriving at 20/03/2026 09:55:00. 50 Economy ticket for £47 per person are available. Travel duration is 19h 0m
Fastest Buses Thursday
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 21/03/2026 08:45:00 to Central Coach Station, Detroit (USA) arriving at 21/03/2026 22:55:00. 50 Economy ticket for £54 per person are available. Travel duration is 13h 10m
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FlixBus13h 50m016:00St. Louis, MOGateway Station06:50DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 21/03/2026 16:00:00 to Central Coach Station, Detroit (USA) arriving at 22/03/2026 06:50:00. 50 Economy ticket for £55 per person are available. Travel duration is 13h 50m
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FlixBus14h 15m023:30St. Louis, MOGateway Station14:45DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 21/03/2026 23:30:00 to Central Coach Station, Detroit (USA) arriving at 22/03/2026 14:45:00. 50 Economy ticket for £52 per person are available. Travel duration is 14h 15m
Fastest Buses Saturday
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United Airlines4h 30m007:41St. Louis Lambert AirportSt. Louis Lambert Airport13:11Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 22/03/2026 07:41:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 22/03/2026 13:11:00. 50 Economy ticket for £176 per person are available. Travel duration is 4h 30m
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United Airlines5h 46m006:25St. Louis Lambert AirportSt. Louis Lambert Airport13:11Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 22/03/2026 06:25:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 22/03/2026 13:11:00. 50 Economy ticket for £176 per person are available. Travel duration is 5h 46m
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Alaska Airlines22h 36m016:20St. Louis Lambert AirportSt. Louis Lambert Airport15:56Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Alaska Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 22/03/2026 16:20:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 23/03/2026 15:56:00. 50 Economy ticket for £391 per person are available. Travel duration is 22h 36m
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Frontier Airlines25h 52m022:47St. Louis Lambert AirportSt. Louis Lambert Airport01:39Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 22/03/2026 22:47:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 24/03/2026 01:39:00. 50 Economy ticket for £166 per person are available. Travel duration is 25h 52m
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Frontier Airlines31h 29m020:06St. Louis Lambert AirportSt. Louis Lambert Airport04:35Detroit Metropolitan Wayne County AirportDetroit Metropolitan Wayne County Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 22/03/2026 20:06:00 to Detroit Metropolitan Wayne County Airport, Detroit Metropolitan Wayne County Airport (USA) arriving at 24/03/2026 04:35:00. 50 Economy ticket for £162 per person are available. Travel duration is 31h 29m
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Greyhound US13h 10m008:45St. Louis, MOGateway Station22:55DetroitCentral Coach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 22/03/2026 08:45:00 to Central Coach Station, Detroit (USA) arriving at 22/03/2026 22:55:00. 50 Economy ticket for £61 per person are available. Travel duration is 13h 10m
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FlixBus13h 50m016:00St. Louis, MOGateway Station06:50DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 22/03/2026 16:00:00 to Central Coach Station, Detroit (USA) arriving at 23/03/2026 06:50:00. 50 Economy ticket for £61 per person are available. Travel duration is 13h 50m
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FlixBus14h 15m023:30St. Louis, MOGateway Station14:45DetroitCentral Coach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 22/03/2026 23:30:00 to Central Coach Station, Detroit (USA) arriving at 23/03/2026 14:45:00. 50 Economy ticket for £61 per person are available. Travel duration is 14h 15m
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Here you will find all operators and timetables for a
Bus from St. Louis, MO to Detroit
What are the most popular stations in St. Louis, MO and Detroit?
In St. Louis, MO, you will usually depart from Gateway Station, Lindbergh @ Hackberry NB Bus Stop or Skinker Boulevard, while in Detroit you will be arriving at Central Coach Station, Amtrak or Park Avenue, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Detroit from St. Louis, MO? With 7 connections between 2 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between St. Louis, MO and Detroit, you can pay as low as £45 with a Bus from Greyhound US.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from United Airlines: you will get to Detroit in just 3h 47m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting St. Louis, MO and Detroit are FlixBus, Greyhound US and Frontier Airlines, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in St. Louis, MO and Detroit is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Sauget, IL or to Windsor, ON, and look at flights from St. Louis Lambert Airport, and landing at Detroit Metropolitan Wayne County Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from St. Louis, MO to Detroit?
The most popular companies between St. Louis, MO and Detroit, are FlixBus, Greyhound US and Frontier Airlines. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus and Greyhound US
Airlines: Frontier Airlines, United Airlines, Allegiant Air and 3 more.
All you need to know when you travel from St. Louis, MO to Detroit
Check all information on comfort and services on all modes of transports from St. Louis, MO to Detroit. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from St. Louis, MO to Detroit
How can I reach Detroit from St. Louis, MO?
Every day, there are on average 7 connections between Flight and Bus, with which you can get to Detroit from St. Louis, MO.
How far is Detroit from St. Louis, MO?
The distance between St. Louis, MO and Detroit is 731.6 km.
What is the most ecofriendly mode of transport between St. Louis, MO and Detroit?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 20 kgs of CO2, a train 26 kgs, a car 124 kgs, and a flight 180 kgs.
What is the cheapest mode of transport from St. Louis, MO to Detroit?
You can get to Detroit with just £45 by taking a Bus from Greyhound US.
What is the fastest way to get from St. Louis, MO to Detroit?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Detroit in just 3h 47m with a Flight from United Airlines.
More routes to St. Louis, MO and to Detroit
Looking for more options? Here you can see the most popular routes to St. Louis, MO and to Detroit. Simply click on a connection, and you’ll find all the details about the route!
