How to get from Siena to Palermo

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What is the best way to travel from Siena to Palermo?

Looking for a trip? Check and compare all the available Trains and Buses to Palermo from Siena. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
Bus is the cheapest, while Train is the fastest way on this route
Transport type
Travel time
Cheapest price
Average price
Daily departures
Bus
16h 0m
£38
£75
3
Train
14h 40m
£126
£129
2

What is the cheapest way to reach Palermo from Siena?

You can reach Palermo with just £38 by taking a Bus from FlixBus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.

Thursday
Friday
Saturday
Sunday
Monday
from £38
Tuesday
Wednesday
from £118

    Cheapest Buses Monday

  • FlixBus
    18h 15m
    0
    21:00
    Siena
    Train Station
    15:15
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    £38
  • FlixBus
    20h 55m
    0
    22:25
    Siena
    Train Station
    19:20
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    £41
  • FlixBus
    16h 0m
    0
    19:00
    Siena
    Train Station
    11:00
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    £49

    Cheapest Buses Wednesday

  • FlixBus
    16h 0m
    0
    19:00
    Siena
    Train Station
    11:00
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    £118
  • FlixBus
    20h 55m
    0
    22:25
    Siena
    Train Station
    19:20
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    £127
  • Cheapest Trains Wednesday

  • Trenitalia
    14h 40m
    0
    08:18
    Siena
    Train Station
    22:58
    Palermo
    Central Station
    0
    Trenitalia
    Economy
    from £126
  • Trenitalia
    17h 54m
    0
    19:18
    Siena
    Train Station
    13:12
    Palermo
    Central Station
    0
    Trenitalia
    Economy
    from £132

What are the fastest trips from Siena to Palermo?

You can get to Palermo from Siena in just 14h 40m with a Train from Trenitalia. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.

Thursday
Friday
Saturday
Sunday
Monday
from 16h 0m
Tuesday
Wednesday
from 14h 40m

    Fastest Buses Monday

  • FlixBus
    16h 0m
    0
    19:00
    Siena
    Train Station
    11:00
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    £49
  • FlixBus
    18h 15m
    0
    21:00
    Siena
    Train Station
    15:15
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    £38
  • FlixBus
    20h 55m
    0
    22:25
    Siena
    Train Station
    19:20
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    £41

    Fastest Trains Wednesday

  • Trenitalia
    14h 40m
    0
    08:18
    Siena
    Train Station
    22:58
    Palermo
    Central Station
    0
    Trenitalia
    Economy
    from £126
  • Trenitalia
    17h 54m
    0
    19:18
    Siena
    Train Station
    13:12
    Palermo
    Central Station
    0
    Trenitalia
    Economy
    from £132
  • Fastest Buses Wednesday

  • FlixBus
    16h 0m
    0
    19:00
    Siena
    Train Station
    11:00
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    £118
  • FlixBus
    20h 55m
    0
    22:25
    Siena
    Train Station
    19:20
    Palermo
    Via Tommaso Fazello Bus Stop
    0
    FlixBus
    Economy
    £127
Here you will find all operators and timetables for a Bus from Siena to Palermo

What are the most popular stations in Siena and Palermo?

In Siena, you will usually depart from Train Station, Bus Stop or Central Bus Station, while in Palermo you will be arriving at Cinisi Via Nazionale Coach Stop, Via Belgio or Via Fazello, but there are many more stops to explore in both locations.

How do I decide? Some tips and tricks from our experience

Are you having trouble deciding on how to get to Palermo from Siena? With 3 connections between 2 Train and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.

Look for the lowest price

Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Siena and Palermo, you can pay as low as £38 with a Bus from FlixBus.

Travel duration

Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Train from Trenitalia: you will get to Palermo in just 14h 40m.

Comfort makes all the difference

You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Siena and Palermo are FlixBus and Trenitalia, but be sure to check what they have to offer!

Save money with deals, and always compare

One last tip? Even if you live in Siena and Palermo is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Castagno or to Ciaculli, and look at flights from , and landing at Palermo Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!

Which companies offer a trip from Siena to Palermo?

The most popular companies between Siena and Palermo, are FlixBus and Trenitalia. Be sure to check their seat class offers and the amenities that they provide.

Bus companies: FlixBus

Train companies: Trenitalia

All you need to know when you travel from Siena to Palermo

Check all information on comfort and services on all modes of transports from Siena to Palermo. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.

FAQs about the trip from Siena to Palermo

How can I reach Palermo from Siena?

Every day, there are on average 3 connections between Train and Bus, with which you can get to Palermo from Siena.

How far is Palermo from Siena?

The distance between Siena and Palermo is 603.3 km.

What is the most ecofriendly mode of transport between Siena and Palermo?

Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance. On this particular route, a bus will emit, per person, a total of 16 kgs of CO2, a train 21 kgs, a car 103 kgs, and a flight 148 kgs.

What is the cheapest mode of transport from Siena to Palermo?

You can get to Palermo with just £38 by taking a Bus from FlixBus.

What is the fastest way to get from Siena to Palermo?

While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Palermo in just 14h 40m with a Train from Trenitalia.

More routes to Siena and to Palermo

Looking for more options? Here you can see the most popular routes to Siena and to Palermo. Simply click on a connection, and you’ll find all the details about the route!

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