What is the best way to travel from Santa Maria, CA to San Diego?
Looking for a trip? Check and compare all the available Flights to San Diego from Santa Maria, CA. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all available companies to find your perfect trip!
What is the cheapest way to reach San Diego from Santa Maria, CA?
You can reach San Diego with just £146 by taking a Flight from Skyscanner, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
-
Skyscanner1h 22m006:00San Luis Obispo County AirportSan Luis Obispo County Airport07:22San Diego AirportSan Diego Airport0EconomyA Flight from Skyscanner goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 22/12/2025 06:00:00 to San Diego Airport, San Diego Airport (USA) arriving at 22/12/2025 07:22:00. 50 Economy ticket for £147 per person are available. Travel duration is 1h 22m
-
Skyscanner1h 25m017:20San Luis Obispo County AirportSan Luis Obispo County Airport18:45San Diego AirportSan Diego Airport0EconomyA Flight from Skyscanner goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 22/12/2025 17:20:00 to San Diego Airport, San Diego Airport (USA) arriving at 22/12/2025 18:45:00. 50 Economy ticket for £167 per person are available. Travel duration is 1h 25m
-
Alaska Airlines24h 13m019:45San Luis Obispo County AirportSan Luis Obispo County Airport19:58Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 22/12/2025 19:45:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 23/12/2025 19:58:00. 50 Economy ticket for £298 per person are available. Travel duration is 24h 13m
-
Alaska Airlines24h 0m019:45San Luis Obispo County AirportSan Luis Obispo County Airport19:45Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 22/12/2025 19:45:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 23/12/2025 19:45:00. 50 Economy ticket for £323 per person are available. Travel duration is 24h 0m
-
Alaska Airlines11h 10m006:00San Luis Obispo County AirportSan Luis Obispo County Airport17:10Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 22/12/2025 06:00:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 22/12/2025 17:10:00. 50 Economy ticket for £345 per person are available. Travel duration is 11h 10m
-
Alaska Airlines13h 45m006:00San Luis Obispo County AirportSan Luis Obispo County Airport19:45Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 22/12/2025 06:00:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 22/12/2025 19:45:00. 50 Economy ticket for £357 per person are available. Travel duration is 13h 45m
-
Alaska Airlines18h 25m019:45San Luis Obispo County AirportSan Luis Obispo County Airport14:10Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 22/12/2025 19:45:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 23/12/2025 14:10:00. 50 Economy ticket for £369 per person are available. Travel duration is 18h 25m
-
United Airlines5h 52m018:23San Luis Obispo County AirportSan Luis Obispo County Airport00:15San Diego AirportSan Diego Airport0EconomyA Flight from United Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 22/12/2025 18:23:00 to San Diego Airport, San Diego Airport (USA) arriving at 23/12/2025 00:15:00. 50 Economy ticket for £422 per person are available. Travel duration is 5h 52m
-
Alaska Airlines5h 42m017:25San Luis Obispo County AirportSan Luis Obispo County Airport23:07San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 22/12/2025 17:25:00 to San Diego Airport, San Diego Airport (USA) arriving at 22/12/2025 23:07:00. 50 Economy ticket for £430 per person are available. Travel duration is 5h 42m
-
Alaska Airlines6h 54m015:55San Luis Obispo County AirportSan Luis Obispo County Airport22:49San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 22/12/2025 15:55:00 to San Diego Airport, San Diego Airport (USA) arriving at 22/12/2025 22:49:00. 50 Economy ticket for £437 per person are available. Travel duration is 6h 54m
Cheapest Flights Monday
-
Skyscanner1h 22m006:00San Luis Obispo County AirportSan Luis Obispo County Airport07:22San Diego AirportSan Diego Airport0EconomyA Flight from Skyscanner goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 23/12/2025 06:00:00 to San Diego Airport, San Diego Airport (USA) arriving at 23/12/2025 07:22:00. 50 Economy ticket for £147 per person are available. Travel duration is 1h 22m
-
Skyscanner1h 25m017:20San Luis Obispo County AirportSan Luis Obispo County Airport18:45San Diego AirportSan Diego Airport0EconomyA Flight from Skyscanner goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 23/12/2025 17:20:00 to San Diego Airport, San Diego Airport (USA) arriving at 23/12/2025 18:45:00. 50 Economy ticket for £271 per person are available. Travel duration is 1h 25m
-
Alaska Airlines13h 58m006:00San Luis Obispo County AirportSan Luis Obispo County Airport19:58Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 23/12/2025 06:00:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 23/12/2025 19:58:00. 50 Economy ticket for £331 per person are available. Travel duration is 13h 58m
-
Alaska Airlines11h 10m006:00San Luis Obispo County AirportSan Luis Obispo County Airport17:10Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 23/12/2025 06:00:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 23/12/2025 17:10:00. 50 Economy ticket for £376 per person are available. Travel duration is 11h 10m
-
Skyscanner3h 27m007:03San Luis Obispo County AirportSan Luis Obispo County Airport10:30San Diego AirportSan Diego Airport0EconomyA Flight from Skyscanner goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 23/12/2025 07:03:00 to San Diego Airport, San Diego Airport (USA) arriving at 23/12/2025 10:30:00. 50 Economy ticket for £567 per person are available. Travel duration is 3h 27m
-
Alaska Airlines6h 50m015:55San Luis Obispo County AirportSan Luis Obispo County Airport22:45San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 23/12/2025 15:55:00 to San Diego Airport, San Diego Airport (USA) arriving at 23/12/2025 22:45:00. 50 Economy ticket for £606 per person are available. Travel duration is 6h 50m
-
Alaska Airlines5h 42m017:25San Luis Obispo County AirportSan Luis Obispo County Airport23:07San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 23/12/2025 17:25:00 to San Diego Airport, San Diego Airport (USA) arriving at 23/12/2025 23:07:00. 50 Economy ticket for £621 per person are available. Travel duration is 5h 42m
Cheapest Flights Tuesday
-
Skyscanner1h 22m006:00San Luis Obispo County AirportSan Luis Obispo County Airport07:22San Diego AirportSan Diego Airport0EconomyA Flight from Skyscanner goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 25/12/2025 06:00:00 to San Diego Airport, San Diego Airport (USA) arriving at 25/12/2025 07:22:00. 50 Economy ticket for £146 per person are available. Travel duration is 1h 22m
-
Skyscanner1h 25m017:24San Luis Obispo County AirportSan Luis Obispo County Airport18:49San Diego AirportSan Diego Airport0EconomyA Flight from Skyscanner goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 25/12/2025 17:24:00 to San Diego Airport, San Diego Airport (USA) arriving at 25/12/2025 18:49:00. 50 Economy ticket for £167 per person are available. Travel duration is 1h 25m
-
Alaska Airlines13h 58m006:00San Luis Obispo County AirportSan Luis Obispo County Airport19:58Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 25/12/2025 06:00:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 25/12/2025 19:58:00. 50 Economy ticket for £353 per person are available. Travel duration is 13h 58m
-
Alaska Airlines13h 45m006:00San Luis Obispo County AirportSan Luis Obispo County Airport19:45Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 25/12/2025 06:00:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 25/12/2025 19:45:00. 50 Economy ticket for £377 per person are available. Travel duration is 13h 45m
-
Alaska Airlines5h 42m017:25San Luis Obispo County AirportSan Luis Obispo County Airport23:07San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 25/12/2025 17:25:00 to San Diego Airport, San Diego Airport (USA) arriving at 25/12/2025 23:07:00. 50 Economy ticket for £383 per person are available. Travel duration is 5h 42m
-
Alaska Airlines6h 50m015:55San Luis Obispo County AirportSan Luis Obispo County Airport22:45San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 25/12/2025 15:55:00 to San Diego Airport, San Diego Airport (USA) arriving at 25/12/2025 22:45:00. 50 Economy ticket for £405 per person are available. Travel duration is 6h 50m
-
Alaska Airlines24h 0m019:45San Luis Obispo County AirportSan Luis Obispo County Airport19:45Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 25/12/2025 19:45:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 26/12/2025 19:45:00. 50 Economy ticket for £410 per person are available. Travel duration is 24h 0m
-
United Airlines4h 47m008:15San Luis Obispo County AirportSan Luis Obispo County Airport13:02San Diego AirportSan Diego Airport0EconomyA Flight from United Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 25/12/2025 08:15:00 to San Diego Airport, San Diego Airport (USA) arriving at 25/12/2025 13:02:00. 50 Economy ticket for £420 per person are available. Travel duration is 4h 47m
-
Alaska Airlines21h 25m019:45San Luis Obispo County AirportSan Luis Obispo County Airport17:10Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 25/12/2025 19:45:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 26/12/2025 17:10:00. 50 Economy ticket for £421 per person are available. Travel duration is 21h 25m
-
Alaska Airlines18h 25m019:45San Luis Obispo County AirportSan Luis Obispo County Airport14:10Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 25/12/2025 19:45:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 26/12/2025 14:10:00. 50 Economy ticket for £429 per person are available. Travel duration is 18h 25m
Cheapest Flights Thursday
-
Skyscanner1h 22m006:00San Luis Obispo County AirportSan Luis Obispo County Airport07:22San Diego AirportSan Diego Airport0EconomyA Flight from Skyscanner goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 28/12/2025 06:00:00 to San Diego Airport, San Diego Airport (USA) arriving at 28/12/2025 07:22:00. 50 Economy ticket for £147 per person are available. Travel duration is 1h 22m
-
Skyscanner1h 25m017:20San Luis Obispo County AirportSan Luis Obispo County Airport18:45San Diego AirportSan Diego Airport0EconomyA Flight from Skyscanner goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 28/12/2025 17:20:00 to San Diego Airport, San Diego Airport (USA) arriving at 28/12/2025 18:45:00. 50 Economy ticket for £167 per person are available. Travel duration is 1h 25m
-
Alaska Airlines24h 0m019:45San Luis Obispo County AirportSan Luis Obispo County Airport19:45Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 28/12/2025 19:45:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 29/12/2025 19:45:00. 50 Economy ticket for £305 per person are available. Travel duration is 24h 0m
-
Alaska Airlines18h 25m019:45San Luis Obispo County AirportSan Luis Obispo County Airport14:10Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 28/12/2025 19:45:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 29/12/2025 14:10:00. 50 Economy ticket for £305 per person are available. Travel duration is 18h 25m
-
United Airlines6h 27m014:21San Luis Obispo County AirportSan Luis Obispo County Airport20:48San Diego AirportSan Diego Airport0EconomyA Flight from United Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 28/12/2025 14:21:00 to San Diego Airport, San Diego Airport (USA) arriving at 28/12/2025 20:48:00. 50 Economy ticket for £422 per person are available. Travel duration is 6h 27m
-
United Airlines5h 52m018:23San Luis Obispo County AirportSan Luis Obispo County Airport00:15San Diego AirportSan Diego Airport0EconomyA Flight from United Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 28/12/2025 18:23:00 to San Diego Airport, San Diego Airport (USA) arriving at 29/12/2025 00:15:00. 50 Economy ticket for £422 per person are available. Travel duration is 5h 52m
-
Alaska Airlines6h 50m015:55San Luis Obispo County AirportSan Luis Obispo County Airport22:45San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 28/12/2025 15:55:00 to San Diego Airport, San Diego Airport (USA) arriving at 28/12/2025 22:45:00. 50 Economy ticket for £505 per person are available. Travel duration is 6h 50m
-
Alaska Airlines11h 10m006:00San Luis Obispo County AirportSan Luis Obispo County Airport17:10Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 28/12/2025 06:00:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 28/12/2025 17:10:00. 50 Economy ticket for £682 per person are available. Travel duration is 11h 10m
Cheapest Flights Sunday
What are the fastest trips from Santa Maria, CA to San Diego?
You can get to San Diego from Santa Maria, CA in just 1h 22m with a Flight from Skyscanner. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
-
Skyscanner1h 22m006:00San Luis Obispo County AirportSan Luis Obispo County Airport07:22San Diego AirportSan Diego Airport0EconomyA Flight from Skyscanner goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 22/12/2025 06:00:00 to San Diego Airport, San Diego Airport (USA) arriving at 22/12/2025 07:22:00. 50 Economy ticket for £147 per person are available. Travel duration is 1h 22m
-
Skyscanner1h 25m017:20San Luis Obispo County AirportSan Luis Obispo County Airport18:45San Diego AirportSan Diego Airport0EconomyA Flight from Skyscanner goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 22/12/2025 17:20:00 to San Diego Airport, San Diego Airport (USA) arriving at 22/12/2025 18:45:00. 50 Economy ticket for £167 per person are available. Travel duration is 1h 25m
-
Alaska Airlines5h 42m017:25San Luis Obispo County AirportSan Luis Obispo County Airport23:07San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 22/12/2025 17:25:00 to San Diego Airport, San Diego Airport (USA) arriving at 22/12/2025 23:07:00. 50 Economy ticket for £430 per person are available. Travel duration is 5h 42m
-
United Airlines5h 52m018:23San Luis Obispo County AirportSan Luis Obispo County Airport00:15San Diego AirportSan Diego Airport0EconomyA Flight from United Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 22/12/2025 18:23:00 to San Diego Airport, San Diego Airport (USA) arriving at 23/12/2025 00:15:00. 50 Economy ticket for £422 per person are available. Travel duration is 5h 52m
-
Alaska Airlines6h 54m015:55San Luis Obispo County AirportSan Luis Obispo County Airport22:49San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 22/12/2025 15:55:00 to San Diego Airport, San Diego Airport (USA) arriving at 22/12/2025 22:49:00. 50 Economy ticket for £437 per person are available. Travel duration is 6h 54m
-
Alaska Airlines11h 10m006:00San Luis Obispo County AirportSan Luis Obispo County Airport17:10Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 22/12/2025 06:00:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 22/12/2025 17:10:00. 50 Economy ticket for £345 per person are available. Travel duration is 11h 10m
-
Alaska Airlines13h 45m006:00San Luis Obispo County AirportSan Luis Obispo County Airport19:45Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 22/12/2025 06:00:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 22/12/2025 19:45:00. 50 Economy ticket for £357 per person are available. Travel duration is 13h 45m
-
Alaska Airlines18h 25m019:45San Luis Obispo County AirportSan Luis Obispo County Airport14:10Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 22/12/2025 19:45:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 23/12/2025 14:10:00. 50 Economy ticket for £369 per person are available. Travel duration is 18h 25m
-
Alaska Airlines24h 0m019:45San Luis Obispo County AirportSan Luis Obispo County Airport19:45Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 22/12/2025 19:45:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 23/12/2025 19:45:00. 50 Economy ticket for £323 per person are available. Travel duration is 24h 0m
-
Alaska Airlines24h 13m019:45San Luis Obispo County AirportSan Luis Obispo County Airport19:58Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 22/12/2025 19:45:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 23/12/2025 19:58:00. 50 Economy ticket for £298 per person are available. Travel duration is 24h 13m
Fastest Flights Monday
-
Skyscanner1h 22m006:00San Luis Obispo County AirportSan Luis Obispo County Airport07:22San Diego AirportSan Diego Airport0EconomyA Flight from Skyscanner goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 23/12/2025 06:00:00 to San Diego Airport, San Diego Airport (USA) arriving at 23/12/2025 07:22:00. 50 Economy ticket for £147 per person are available. Travel duration is 1h 22m
-
Skyscanner1h 25m017:20San Luis Obispo County AirportSan Luis Obispo County Airport18:45San Diego AirportSan Diego Airport0EconomyA Flight from Skyscanner goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 23/12/2025 17:20:00 to San Diego Airport, San Diego Airport (USA) arriving at 23/12/2025 18:45:00. 50 Economy ticket for £271 per person are available. Travel duration is 1h 25m
-
Skyscanner3h 27m007:03San Luis Obispo County AirportSan Luis Obispo County Airport10:30San Diego AirportSan Diego Airport0EconomyA Flight from Skyscanner goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 23/12/2025 07:03:00 to San Diego Airport, San Diego Airport (USA) arriving at 23/12/2025 10:30:00. 50 Economy ticket for £567 per person are available. Travel duration is 3h 27m
-
Alaska Airlines5h 42m017:25San Luis Obispo County AirportSan Luis Obispo County Airport23:07San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 23/12/2025 17:25:00 to San Diego Airport, San Diego Airport (USA) arriving at 23/12/2025 23:07:00. 50 Economy ticket for £621 per person are available. Travel duration is 5h 42m
-
Alaska Airlines6h 50m015:55San Luis Obispo County AirportSan Luis Obispo County Airport22:45San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 23/12/2025 15:55:00 to San Diego Airport, San Diego Airport (USA) arriving at 23/12/2025 22:45:00. 50 Economy ticket for £606 per person are available. Travel duration is 6h 50m
-
Alaska Airlines11h 10m006:00San Luis Obispo County AirportSan Luis Obispo County Airport17:10Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 23/12/2025 06:00:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 23/12/2025 17:10:00. 50 Economy ticket for £376 per person are available. Travel duration is 11h 10m
-
Alaska Airlines13h 58m006:00San Luis Obispo County AirportSan Luis Obispo County Airport19:58Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 23/12/2025 06:00:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 23/12/2025 19:58:00. 50 Economy ticket for £331 per person are available. Travel duration is 13h 58m
Fastest Flights Tuesday
-
Skyscanner1h 22m006:00San Luis Obispo County AirportSan Luis Obispo County Airport07:22San Diego AirportSan Diego Airport0EconomyA Flight from Skyscanner goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 25/12/2025 06:00:00 to San Diego Airport, San Diego Airport (USA) arriving at 25/12/2025 07:22:00. 50 Economy ticket for £146 per person are available. Travel duration is 1h 22m
-
Skyscanner1h 25m017:24San Luis Obispo County AirportSan Luis Obispo County Airport18:49San Diego AirportSan Diego Airport0EconomyA Flight from Skyscanner goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 25/12/2025 17:24:00 to San Diego Airport, San Diego Airport (USA) arriving at 25/12/2025 18:49:00. 50 Economy ticket for £167 per person are available. Travel duration is 1h 25m
-
United Airlines4h 47m008:15San Luis Obispo County AirportSan Luis Obispo County Airport13:02San Diego AirportSan Diego Airport0EconomyA Flight from United Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 25/12/2025 08:15:00 to San Diego Airport, San Diego Airport (USA) arriving at 25/12/2025 13:02:00. 50 Economy ticket for £420 per person are available. Travel duration is 4h 47m
-
Alaska Airlines5h 42m017:25San Luis Obispo County AirportSan Luis Obispo County Airport23:07San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 25/12/2025 17:25:00 to San Diego Airport, San Diego Airport (USA) arriving at 25/12/2025 23:07:00. 50 Economy ticket for £383 per person are available. Travel duration is 5h 42m
-
Alaska Airlines6h 50m015:55San Luis Obispo County AirportSan Luis Obispo County Airport22:45San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 25/12/2025 15:55:00 to San Diego Airport, San Diego Airport (USA) arriving at 25/12/2025 22:45:00. 50 Economy ticket for £405 per person are available. Travel duration is 6h 50m
-
Alaska Airlines13h 45m006:00San Luis Obispo County AirportSan Luis Obispo County Airport19:45Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 25/12/2025 06:00:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 25/12/2025 19:45:00. 50 Economy ticket for £377 per person are available. Travel duration is 13h 45m
-
Alaska Airlines13h 58m006:00San Luis Obispo County AirportSan Luis Obispo County Airport19:58Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 25/12/2025 06:00:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 25/12/2025 19:58:00. 50 Economy ticket for £353 per person are available. Travel duration is 13h 58m
-
Alaska Airlines18h 25m019:45San Luis Obispo County AirportSan Luis Obispo County Airport14:10Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 25/12/2025 19:45:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 26/12/2025 14:10:00. 50 Economy ticket for £429 per person are available. Travel duration is 18h 25m
-
Alaska Airlines21h 25m019:45San Luis Obispo County AirportSan Luis Obispo County Airport17:10Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 25/12/2025 19:45:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 26/12/2025 17:10:00. 50 Economy ticket for £421 per person are available. Travel duration is 21h 25m
-
Alaska Airlines24h 0m019:45San Luis Obispo County AirportSan Luis Obispo County Airport19:45Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 25/12/2025 19:45:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 26/12/2025 19:45:00. 50 Economy ticket for £410 per person are available. Travel duration is 24h 0m
Fastest Flights Thursday
-
Skyscanner1h 22m006:00San Luis Obispo County AirportSan Luis Obispo County Airport07:22San Diego AirportSan Diego Airport0EconomyA Flight from Skyscanner goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 28/12/2025 06:00:00 to San Diego Airport, San Diego Airport (USA) arriving at 28/12/2025 07:22:00. 50 Economy ticket for £147 per person are available. Travel duration is 1h 22m
-
Skyscanner1h 25m017:20San Luis Obispo County AirportSan Luis Obispo County Airport18:45San Diego AirportSan Diego Airport0EconomyA Flight from Skyscanner goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 28/12/2025 17:20:00 to San Diego Airport, San Diego Airport (USA) arriving at 28/12/2025 18:45:00. 50 Economy ticket for £167 per person are available. Travel duration is 1h 25m
-
United Airlines5h 52m018:23San Luis Obispo County AirportSan Luis Obispo County Airport00:15San Diego AirportSan Diego Airport0EconomyA Flight from United Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 28/12/2025 18:23:00 to San Diego Airport, San Diego Airport (USA) arriving at 29/12/2025 00:15:00. 50 Economy ticket for £422 per person are available. Travel duration is 5h 52m
-
United Airlines6h 27m014:21San Luis Obispo County AirportSan Luis Obispo County Airport20:48San Diego AirportSan Diego Airport0EconomyA Flight from United Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 28/12/2025 14:21:00 to San Diego Airport, San Diego Airport (USA) arriving at 28/12/2025 20:48:00. 50 Economy ticket for £422 per person are available. Travel duration is 6h 27m
-
Alaska Airlines6h 50m015:55San Luis Obispo County AirportSan Luis Obispo County Airport22:45San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 28/12/2025 15:55:00 to San Diego Airport, San Diego Airport (USA) arriving at 28/12/2025 22:45:00. 50 Economy ticket for £505 per person are available. Travel duration is 6h 50m
-
Alaska Airlines11h 10m006:00San Luis Obispo County AirportSan Luis Obispo County Airport17:10Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 28/12/2025 06:00:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 28/12/2025 17:10:00. 50 Economy ticket for £682 per person are available. Travel duration is 11h 10m
-
Alaska Airlines18h 25m019:45San Luis Obispo County AirportSan Luis Obispo County Airport14:10Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 28/12/2025 19:45:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 29/12/2025 14:10:00. 50 Economy ticket for £305 per person are available. Travel duration is 18h 25m
-
Alaska Airlines24h 0m019:45San Luis Obispo County AirportSan Luis Obispo County Airport19:45Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from San Luis Obispo County Airport, San Luis Obispo County Airport (USA) at 28/12/2025 19:45:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 29/12/2025 19:45:00. 50 Economy ticket for £305 per person are available. Travel duration is 24h 0m
Fastest Flights Sunday
Here you will find all operators and timetables for a
Bus from Santa Maria, CA to San Diego
What are the most popular stations in Santa Maria, CA and San Diego?
In Santa Maria, CA, you will usually depart from Nicholson Ave, Ihop or Transit Center, while in San Diego you will be arriving at San Ysidro Transit Center, University Av & Bancroft St Coach Stop or Old Town Transit Center, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to San Diego from Santa Maria, CA? With 8 connections between Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Santa Maria, CA and San Diego, you can pay as low as £146 with a Flight from Skyscanner.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Skyscanner: you will get to San Diego in just 1h 22m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Santa Maria, CA and San Diego are Alaska Airlines, Skyscanner and United Airlines, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Santa Maria, CA and San Diego is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Santa Maria Airport or to San Diego Airport, and look at flights from San Luis Obispo County Airport, and landing at Tijuana Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Santa Maria, CA to San Diego?
The most popular companies between Santa Maria, CA and San Diego, are Alaska Airlines, Skyscanner and United Airlines. Be sure to check their seat class offers and the amenities that they provide.
Airlines: Alaska Airlines, Skyscanner and United Airlines
All you need to know when you travel from Santa Maria, CA to San Diego
Check all information on comfort and services on all modes of transports from Santa Maria, CA to San Diego. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Santa Maria, CA to San Diego
How can I reach San Diego from Santa Maria, CA?
Every day, there are on average 8 connections between Flight, with which you can get to San Diego from Santa Maria, CA.
How far is San Diego from Santa Maria, CA?
The distance between Santa Maria, CA and San Diego is 391.8 km.
What is the most ecofriendly mode of transport between Santa Maria, CA and San Diego?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 11 kgs of CO2, a train 14 kgs, a car 67 kgs, and a flight 96 kgs.
What is the cheapest mode of transport from Santa Maria, CA to San Diego?
You can get to San Diego with just £146 by taking a Flight from Skyscanner.
What is the fastest way to get from Santa Maria, CA to San Diego?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to San Diego in just 1h 22m with a Flight from Skyscanner.
More routes to Santa Maria, CA and to San Diego
Looking for more options? Here you can see the most popular routes to Santa Maria, CA and to San Diego. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Santa Maria, CA
- Tijuana, BC to Santa Maria, CA
