What is the best way to travel from San Diego to Indianapolis?
Looking for a trip? Check and compare all the available Buses and Flights to Indianapolis from San Diego. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Indianapolis from San Diego?
You can reach Indianapolis with just £111 by taking a Flight from Frontier Airlines, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Frontier Airlines10h 28m006:25San Diego AirportSan Diego Airport19:53Indianapolis AirportIndianapolis Airport0EconomyA Flight from Frontier Airlines goes from San Diego Airport, San Diego Airport (USA) at 18/12/2025 06:25:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 18/12/2025 19:53:00. 50 Economy ticket for £111 per person are available. Travel duration is 10h 28m
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United Airlines7h 3m007:00San Diego AirportSan Diego Airport17:03Indianapolis AirportIndianapolis Airport0EconomyA Flight from United Airlines goes from San Diego Airport, San Diego Airport (USA) at 18/12/2025 07:00:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 18/12/2025 17:03:00. 50 Economy ticket for £171 per person are available. Travel duration is 7h 3m
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Allegiant Air20h 29m017:05San Diego AirportSan Diego Airport16:34Indianapolis AirportIndianapolis Airport0EconomyA Flight from Allegiant Air goes from San Diego Airport, San Diego Airport (USA) at 18/12/2025 17:05:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 19/12/2025 16:34:00. 50 Economy ticket for £239 per person are available. Travel duration is 20h 29m
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Alaska Airlines7h 16m008:05San Diego AirportSan Diego Airport18:21Indianapolis AirportIndianapolis Airport0EconomyA Flight from Alaska Airlines goes from San Diego Airport, San Diego Airport (USA) at 18/12/2025 08:05:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 18/12/2025 18:21:00. 50 Economy ticket for £240 per person are available. Travel duration is 7h 16m
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American Airlines8h 21m007:14San Diego AirportSan Diego Airport18:35Indianapolis AirportIndianapolis Airport0EconomyA Flight from American Airlines goes from San Diego Airport, San Diego Airport (USA) at 18/12/2025 07:14:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 18/12/2025 18:35:00. 50 Economy ticket for £240 per person are available. Travel duration is 8h 21m
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FlixBus58h 55m009:25San DiegoOld Town Transit Center23:20IndianapolisWashington / Delaware0EconomyA Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 18/12/2025 09:25:00 to Washington / Delaware, Indianapolis (USA) arriving at 20/12/2025 23:20:00. 50 Economy ticket for £270 per person are available. Travel duration is 58h 55m
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FlixBus54h 35m013:45San DiegoSeaport Village23:20IndianapolisWashington / Delaware0EconomyA Bus from FlixBus goes from Seaport Village, San Diego (USA) at 18/12/2025 13:45:00 to Washington / Delaware, Indianapolis (USA) arriving at 20/12/2025 23:20:00. 50 Economy ticket for £270 per person are available. Travel duration is 54h 35m
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FlixBus54h 10m014:10San DiegoLa Jolla Village23:20IndianapolisWashington / Delaware0EconomyA Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 18/12/2025 14:10:00 to Washington / Delaware, Indianapolis (USA) arriving at 20/12/2025 23:20:00. 50 Economy ticket for £272 per person are available. Travel duration is 54h 10m
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Greyhound US54h 10m019:35San DiegoOld Town Transit Center04:45IndianapolisCentral Coach Station0EconomyA Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 18/12/2025 19:35:00 to Central Coach Station, Indianapolis (USA) arriving at 21/12/2025 04:45:00. 50 Economy ticket for £314 per person are available. Travel duration is 54h 10m
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Greyhound US57h 50m019:35San DiegoOld Town Transit Center08:25IndianapolisWashington / Delaware0EconomyA Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 18/12/2025 19:35:00 to Washington / Delaware, Indianapolis (USA) arriving at 21/12/2025 08:25:00. 50 Economy ticket for £318 per person are available. Travel duration is 57h 50m
Cheapest Flights Thursday
Cheapest Buses Thursday
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United Airlines8h 33m012:11San Diego AirportSan Diego Airport23:44Indianapolis AirportIndianapolis Airport0EconomyA Flight from United Airlines goes from San Diego Airport, San Diego Airport (USA) at 20/12/2025 12:11:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 20/12/2025 23:44:00. 50 Economy ticket for £186 per person are available. Travel duration is 8h 33m
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Frontier Airlines24h 6m016:47San Diego AirportSan Diego Airport19:53Indianapolis AirportIndianapolis Airport0EconomyA Flight from Frontier Airlines goes from San Diego Airport, San Diego Airport (USA) at 20/12/2025 16:47:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 21/12/2025 19:53:00. 50 Economy ticket for £207 per person are available. Travel duration is 24h 6m
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Alaska Airlines14h 0m006:50San Diego AirportSan Diego Airport23:50Indianapolis AirportIndianapolis Airport0EconomyA Flight from Alaska Airlines goes from San Diego Airport, San Diego Airport (USA) at 20/12/2025 06:50:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 20/12/2025 23:50:00. 50 Economy ticket for £290 per person are available. Travel duration is 14h 0m
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American Airlines8h 11m012:39San Diego AirportSan Diego Airport23:50Indianapolis AirportIndianapolis Airport0EconomyA Flight from American Airlines goes from San Diego Airport, San Diego Airport (USA) at 20/12/2025 12:39:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 20/12/2025 23:50:00. 50 Economy ticket for £296 per person are available. Travel duration is 8h 11m
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Sun Country Airlines19h 12m017:44San Diego AirportSan Diego Airport15:56Indianapolis AirportIndianapolis Airport0EconomyA Flight from Sun Country Airlines goes from San Diego Airport, San Diego Airport (USA) at 20/12/2025 17:44:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 21/12/2025 15:56:00. 50 Economy ticket for £328 per person are available. Travel duration is 19h 12m
Cheapest Flights Saturday
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United Airlines8h 33m012:11San Diego AirportSan Diego Airport23:44Indianapolis AirportIndianapolis Airport0EconomyA Flight from United Airlines goes from San Diego Airport, San Diego Airport (USA) at 22/12/2025 12:11:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 22/12/2025 23:44:00. 50 Economy ticket for £171 per person are available. Travel duration is 8h 33m
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Frontier Airlines23h 53m016:47San Diego AirportSan Diego Airport19:40Indianapolis AirportIndianapolis Airport0EconomyA Flight from Frontier Airlines goes from San Diego Airport, San Diego Airport (USA) at 22/12/2025 16:47:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 23/12/2025 19:40:00. 50 Economy ticket for £207 per person are available. Travel duration is 23h 53m
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American Airlines9h 20m006:15San Diego AirportSan Diego Airport18:35Indianapolis AirportIndianapolis Airport0EconomyA Flight from American Airlines goes from San Diego Airport, San Diego Airport (USA) at 22/12/2025 06:15:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 22/12/2025 18:35:00. 50 Economy ticket for £238 per person are available. Travel duration is 9h 20m
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Alaska Airlines12h 14m019:15San Diego AirportSan Diego Airport10:29Indianapolis AirportIndianapolis Airport0EconomyA Flight from Alaska Airlines goes from San Diego Airport, San Diego Airport (USA) at 22/12/2025 19:15:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 23/12/2025 10:29:00. 50 Economy ticket for £246 per person are available. Travel duration is 12h 14m
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Sun Country Airlines19h 12m017:44San Diego AirportSan Diego Airport15:56Indianapolis AirportIndianapolis Airport0EconomyA Flight from Sun Country Airlines goes from San Diego Airport, San Diego Airport (USA) at 22/12/2025 17:44:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 23/12/2025 15:56:00. 50 Economy ticket for £405 per person are available. Travel duration is 19h 12m
Cheapest Flights Monday
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United Airlines8h 3m010:56San Diego AirportSan Diego Airport21:59Indianapolis AirportIndianapolis Airport0EconomyA Flight from United Airlines goes from San Diego Airport, San Diego Airport (USA) at 23/12/2025 10:56:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 23/12/2025 21:59:00. 50 Economy ticket for £168 per person are available. Travel duration is 8h 3m
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Frontier Airlines43h 39m021:14San Diego AirportSan Diego Airport19:53Indianapolis AirportIndianapolis Airport0EconomyA Flight from Frontier Airlines goes from San Diego Airport, San Diego Airport (USA) at 23/12/2025 21:14:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 25/12/2025 19:53:00. 50 Economy ticket for £171 per person are available. Travel duration is 43h 39m
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Alaska Airlines7h 16m008:05San Diego AirportSan Diego Airport18:21Indianapolis AirportIndianapolis Airport0EconomyA Flight from Alaska Airlines goes from San Diego Airport, San Diego Airport (USA) at 23/12/2025 08:05:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 23/12/2025 18:21:00. 50 Economy ticket for £238 per person are available. Travel duration is 7h 16m
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American Airlines9h 20m006:15San Diego AirportSan Diego Airport18:35Indianapolis AirportIndianapolis Airport0EconomyA Flight from American Airlines goes from San Diego Airport, San Diego Airport (USA) at 23/12/2025 06:15:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 23/12/2025 18:35:00. 50 Economy ticket for £238 per person are available. Travel duration is 9h 20m
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Aeroméxico20h 1m017:29Tijuana AirportTijuana Airport16:30Indianapolis AirportIndianapolis Airport0EconomyA Flight from Aeroméxico goes from Tijuana Airport, Tijuana Airport (Mexico) at 23/12/2025 17:29:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 24/12/2025 16:30:00. 50 Economy ticket for £577 per person are available. Travel duration is 20h 1m
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FlixBus52h 5m012:15San DiegoOld Town Transit Center19:20IndianapolisCentral Coach Station0EconomyA Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 23/12/2025 12:15:00 to Central Coach Station, Indianapolis (USA) arriving at 25/12/2025 19:20:00. 50 Economy ticket for £205 per person are available. Travel duration is 52h 5m
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Greyhound US52h 45m006:45San DiegoOld Town Transit Center14:30IndianapolisCentral Coach Station0EconomyA Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 23/12/2025 06:45:00 to Central Coach Station, Indianapolis (USA) arriving at 25/12/2025 14:30:00. 50 Economy ticket for £206 per person are available. Travel duration is 52h 45m
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FlixBus50h 10m014:10San DiegoLa Jolla Village19:20IndianapolisCentral Coach Station0EconomyA Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 23/12/2025 14:10:00 to Central Coach Station, Indianapolis (USA) arriving at 25/12/2025 19:20:00. 50 Economy ticket for £206 per person are available. Travel duration is 50h 10m
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FlixBus54h 35m013:45San DiegoSeaport Village23:20IndianapolisWashington / Delaware0EconomyA Bus from FlixBus goes from Seaport Village, San Diego (USA) at 23/12/2025 13:45:00 to Washington / Delaware, Indianapolis (USA) arriving at 25/12/2025 23:20:00. 50 Economy ticket for £206 per person are available. Travel duration is 54h 35m
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Greyhound US61h 35m006:45San DiegoOld Town Transit Center23:20IndianapolisWashington / Delaware0EconomyA Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 23/12/2025 06:45:00 to Washington / Delaware, Indianapolis (USA) arriving at 25/12/2025 23:20:00. 50 Economy ticket for £207 per person are available. Travel duration is 61h 35m
Cheapest Flights Tuesday
Cheapest Buses Tuesday
What are the fastest trips from San Diego to Indianapolis?
You can get to Indianapolis from San Diego in just 7h 3m with a Flight from United Airlines. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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United Airlines7h 3m007:00San Diego AirportSan Diego Airport17:03Indianapolis AirportIndianapolis Airport0EconomyA Flight from United Airlines goes from San Diego Airport, San Diego Airport (USA) at 18/12/2025 07:00:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 18/12/2025 17:03:00. 50 Economy ticket for £171 per person are available. Travel duration is 7h 3m
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Alaska Airlines7h 16m008:05San Diego AirportSan Diego Airport18:21Indianapolis AirportIndianapolis Airport0EconomyA Flight from Alaska Airlines goes from San Diego Airport, San Diego Airport (USA) at 18/12/2025 08:05:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 18/12/2025 18:21:00. 50 Economy ticket for £240 per person are available. Travel duration is 7h 16m
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American Airlines8h 21m007:14San Diego AirportSan Diego Airport18:35Indianapolis AirportIndianapolis Airport0EconomyA Flight from American Airlines goes from San Diego Airport, San Diego Airport (USA) at 18/12/2025 07:14:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 18/12/2025 18:35:00. 50 Economy ticket for £240 per person are available. Travel duration is 8h 21m
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Frontier Airlines10h 28m006:25San Diego AirportSan Diego Airport19:53Indianapolis AirportIndianapolis Airport0EconomyA Flight from Frontier Airlines goes from San Diego Airport, San Diego Airport (USA) at 18/12/2025 06:25:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 18/12/2025 19:53:00. 50 Economy ticket for £111 per person are available. Travel duration is 10h 28m
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Allegiant Air20h 29m017:05San Diego AirportSan Diego Airport16:34Indianapolis AirportIndianapolis Airport0EconomyA Flight from Allegiant Air goes from San Diego Airport, San Diego Airport (USA) at 18/12/2025 17:05:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 19/12/2025 16:34:00. 50 Economy ticket for £239 per person are available. Travel duration is 20h 29m
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FlixBus54h 10m014:10San DiegoLa Jolla Village23:20IndianapolisWashington / Delaware0EconomyA Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 18/12/2025 14:10:00 to Washington / Delaware, Indianapolis (USA) arriving at 20/12/2025 23:20:00. 50 Economy ticket for £272 per person are available. Travel duration is 54h 10m
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Greyhound US54h 10m019:35San DiegoOld Town Transit Center04:45IndianapolisCentral Coach Station0EconomyA Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 18/12/2025 19:35:00 to Central Coach Station, Indianapolis (USA) arriving at 21/12/2025 04:45:00. 50 Economy ticket for £314 per person are available. Travel duration is 54h 10m
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FlixBus54h 35m013:45San DiegoSeaport Village23:20IndianapolisWashington / Delaware0EconomyA Bus from FlixBus goes from Seaport Village, San Diego (USA) at 18/12/2025 13:45:00 to Washington / Delaware, Indianapolis (USA) arriving at 20/12/2025 23:20:00. 50 Economy ticket for £270 per person are available. Travel duration is 54h 35m
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Greyhound US57h 50m019:35San DiegoOld Town Transit Center08:25IndianapolisWashington / Delaware0EconomyA Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 18/12/2025 19:35:00 to Washington / Delaware, Indianapolis (USA) arriving at 21/12/2025 08:25:00. 50 Economy ticket for £318 per person are available. Travel duration is 57h 50m
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FlixBus58h 55m009:25San DiegoOld Town Transit Center23:20IndianapolisWashington / Delaware0EconomyA Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 18/12/2025 09:25:00 to Washington / Delaware, Indianapolis (USA) arriving at 20/12/2025 23:20:00. 50 Economy ticket for £270 per person are available. Travel duration is 58h 55m
Fastest Flights Thursday
Fastest Buses Thursday
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American Airlines8h 11m012:39San Diego AirportSan Diego Airport23:50Indianapolis AirportIndianapolis Airport0EconomyA Flight from American Airlines goes from San Diego Airport, San Diego Airport (USA) at 20/12/2025 12:39:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 20/12/2025 23:50:00. 50 Economy ticket for £296 per person are available. Travel duration is 8h 11m
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United Airlines8h 33m012:11San Diego AirportSan Diego Airport23:44Indianapolis AirportIndianapolis Airport0EconomyA Flight from United Airlines goes from San Diego Airport, San Diego Airport (USA) at 20/12/2025 12:11:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 20/12/2025 23:44:00. 50 Economy ticket for £186 per person are available. Travel duration is 8h 33m
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Alaska Airlines14h 0m006:50San Diego AirportSan Diego Airport23:50Indianapolis AirportIndianapolis Airport0EconomyA Flight from Alaska Airlines goes from San Diego Airport, San Diego Airport (USA) at 20/12/2025 06:50:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 20/12/2025 23:50:00. 50 Economy ticket for £290 per person are available. Travel duration is 14h 0m
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Sun Country Airlines19h 12m017:44San Diego AirportSan Diego Airport15:56Indianapolis AirportIndianapolis Airport0EconomyA Flight from Sun Country Airlines goes from San Diego Airport, San Diego Airport (USA) at 20/12/2025 17:44:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 21/12/2025 15:56:00. 50 Economy ticket for £328 per person are available. Travel duration is 19h 12m
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Frontier Airlines24h 6m016:47San Diego AirportSan Diego Airport19:53Indianapolis AirportIndianapolis Airport0EconomyA Flight from Frontier Airlines goes from San Diego Airport, San Diego Airport (USA) at 20/12/2025 16:47:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 21/12/2025 19:53:00. 50 Economy ticket for £207 per person are available. Travel duration is 24h 6m
Fastest Flights Saturday
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United Airlines8h 33m012:11San Diego AirportSan Diego Airport23:44Indianapolis AirportIndianapolis Airport0EconomyA Flight from United Airlines goes from San Diego Airport, San Diego Airport (USA) at 22/12/2025 12:11:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 22/12/2025 23:44:00. 50 Economy ticket for £171 per person are available. Travel duration is 8h 33m
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American Airlines9h 20m006:15San Diego AirportSan Diego Airport18:35Indianapolis AirportIndianapolis Airport0EconomyA Flight from American Airlines goes from San Diego Airport, San Diego Airport (USA) at 22/12/2025 06:15:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 22/12/2025 18:35:00. 50 Economy ticket for £238 per person are available. Travel duration is 9h 20m
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Alaska Airlines12h 14m019:15San Diego AirportSan Diego Airport10:29Indianapolis AirportIndianapolis Airport0EconomyA Flight from Alaska Airlines goes from San Diego Airport, San Diego Airport (USA) at 22/12/2025 19:15:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 23/12/2025 10:29:00. 50 Economy ticket for £246 per person are available. Travel duration is 12h 14m
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Sun Country Airlines19h 12m017:44San Diego AirportSan Diego Airport15:56Indianapolis AirportIndianapolis Airport0EconomyA Flight from Sun Country Airlines goes from San Diego Airport, San Diego Airport (USA) at 22/12/2025 17:44:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 23/12/2025 15:56:00. 50 Economy ticket for £405 per person are available. Travel duration is 19h 12m
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Frontier Airlines23h 53m016:47San Diego AirportSan Diego Airport19:40Indianapolis AirportIndianapolis Airport0EconomyA Flight from Frontier Airlines goes from San Diego Airport, San Diego Airport (USA) at 22/12/2025 16:47:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 23/12/2025 19:40:00. 50 Economy ticket for £207 per person are available. Travel duration is 23h 53m
Fastest Flights Monday
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Alaska Airlines7h 16m008:05San Diego AirportSan Diego Airport18:21Indianapolis AirportIndianapolis Airport0EconomyA Flight from Alaska Airlines goes from San Diego Airport, San Diego Airport (USA) at 23/12/2025 08:05:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 23/12/2025 18:21:00. 50 Economy ticket for £238 per person are available. Travel duration is 7h 16m
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United Airlines8h 3m010:56San Diego AirportSan Diego Airport21:59Indianapolis AirportIndianapolis Airport0EconomyA Flight from United Airlines goes from San Diego Airport, San Diego Airport (USA) at 23/12/2025 10:56:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 23/12/2025 21:59:00. 50 Economy ticket for £168 per person are available. Travel duration is 8h 3m
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American Airlines9h 20m006:15San Diego AirportSan Diego Airport18:35Indianapolis AirportIndianapolis Airport0EconomyA Flight from American Airlines goes from San Diego Airport, San Diego Airport (USA) at 23/12/2025 06:15:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 23/12/2025 18:35:00. 50 Economy ticket for £238 per person are available. Travel duration is 9h 20m
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Aeroméxico20h 1m017:29Tijuana AirportTijuana Airport16:30Indianapolis AirportIndianapolis Airport0EconomyA Flight from Aeroméxico goes from Tijuana Airport, Tijuana Airport (Mexico) at 23/12/2025 17:29:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 24/12/2025 16:30:00. 50 Economy ticket for £577 per person are available. Travel duration is 20h 1m
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Frontier Airlines43h 39m021:14San Diego AirportSan Diego Airport19:53Indianapolis AirportIndianapolis Airport0EconomyA Flight from Frontier Airlines goes from San Diego Airport, San Diego Airport (USA) at 23/12/2025 21:14:00 to Indianapolis Airport, Indianapolis Airport (USA) arriving at 25/12/2025 19:53:00. 50 Economy ticket for £171 per person are available. Travel duration is 43h 39m
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FlixBus50h 10m014:10San DiegoLa Jolla Village19:20IndianapolisCentral Coach Station0EconomyA Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 23/12/2025 14:10:00 to Central Coach Station, Indianapolis (USA) arriving at 25/12/2025 19:20:00. 50 Economy ticket for £206 per person are available. Travel duration is 50h 10m
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FlixBus52h 5m012:15San DiegoOld Town Transit Center19:20IndianapolisCentral Coach Station0EconomyA Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 23/12/2025 12:15:00 to Central Coach Station, Indianapolis (USA) arriving at 25/12/2025 19:20:00. 50 Economy ticket for £205 per person are available. Travel duration is 52h 5m
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Greyhound US52h 45m006:45San DiegoOld Town Transit Center14:30IndianapolisCentral Coach Station0EconomyA Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 23/12/2025 06:45:00 to Central Coach Station, Indianapolis (USA) arriving at 25/12/2025 14:30:00. 50 Economy ticket for £206 per person are available. Travel duration is 52h 45m
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FlixBus54h 35m013:45San DiegoSeaport Village23:20IndianapolisWashington / Delaware0EconomyA Bus from FlixBus goes from Seaport Village, San Diego (USA) at 23/12/2025 13:45:00 to Washington / Delaware, Indianapolis (USA) arriving at 25/12/2025 23:20:00. 50 Economy ticket for £206 per person are available. Travel duration is 54h 35m
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Greyhound US61h 35m006:45San DiegoOld Town Transit Center23:20IndianapolisWashington / Delaware0EconomyA Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 23/12/2025 06:45:00 to Washington / Delaware, Indianapolis (USA) arriving at 25/12/2025 23:20:00. 50 Economy ticket for £207 per person are available. Travel duration is 61h 35m
Fastest Flights Tuesday
Fastest Buses Tuesday
Here you will find all operators and timetables for a
Bus from San Diego to Indianapolis
What are the most popular stations in San Diego and Indianapolis?
In San Diego, you will usually depart from San Ysidro Transit Center, University Av & Bancroft St Coach Stop or Old Town Transit Center, while in Indianapolis you will be arriving at Central Coach Station, Greyhound Bus Station or Downtown Transit Center, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Indianapolis from San Diego? With 7 connections between 2 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between San Diego and Indianapolis, you can pay as low as £111 with a Flight from Frontier Airlines.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from United Airlines: you will get to Indianapolis in just 7h 3m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting San Diego and Indianapolis are FlixBus, Greyhound US and Frontier Airlines, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in San Diego and Indianapolis is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from San Diego Airport or to Beech Grove, IN, and look at flights from Tijuana Airport, and landing at Indianapolis Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from San Diego to Indianapolis?
The most popular companies between San Diego and Indianapolis, are FlixBus, Greyhound US and Frontier Airlines. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus and Greyhound US
Airlines: Frontier Airlines, United Airlines, Alaska Airlines and 4 more.
All you need to know when you travel from San Diego to Indianapolis
Check all information on comfort and services on all modes of transports from San Diego to Indianapolis. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from San Diego to Indianapolis
How can I reach Indianapolis from San Diego?
Every day, there are on average 7 connections between Bus and Flight, with which you can get to Indianapolis from San Diego.
How far is Indianapolis from San Diego?
The distance between San Diego and Indianapolis is 2,872.1 km.
What is the most ecofriendly mode of transport between San Diego and Indianapolis?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 78 kgs of CO2, a train 101 kgs, a car 488 kgs, and a flight 707 kgs.
What is the cheapest mode of transport from San Diego to Indianapolis?
You can get to Indianapolis with just £111 by taking a Flight from Frontier Airlines.
What is the fastest way to get from San Diego to Indianapolis?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Indianapolis in just 7h 3m with a Flight from United Airlines.
More routes to San Diego and to Indianapolis
Looking for more options? Here you can see the most popular routes to San Diego and to Indianapolis. Simply click on a connection, and you’ll find all the details about the route!

