What is the best way to travel from Mainz to Prague?
Looking for a trip? Check and compare all the available Carpool, Buses and Flights to Prague from Mainz. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
What is the cheapest way to reach Prague from Mainz?
You can reach Prague with just £22 by taking a Bus from RegioJet, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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RegioJet6h 45m022:00Frankfurt am Main AirportFrankfurt am Main Airport04:45PragueTrain station Wilsonova0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 03/07/2025 22:00:00 to Train station Wilsonova, Prague (Czech Republic) arriving at 04/07/2025 04:45:00. 50 Economy ticket for £26 per person are available. Travel duration is 6h 45m
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RegioJet6h 48m022:00Frankfurt am Main AirportFrankfurt am Main Airport04:48PragueÚAN Florenc0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 03/07/2025 22:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 04/07/2025 04:48:00. 50 Economy ticket for £26 per person are available. Travel duration is 6h 48m
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FlixBus8h 25m016:00MainzCentral Station00:25PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 03/07/2025 16:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 04/07/2025 00:25:00. 50 Economy ticket for £34 per person are available. Travel duration is 8h 25m
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FlixBus8h 5m016:00MainzCentral Station00:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 03/07/2025 16:00:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 04/07/2025 00:05:00. 50 Economy ticket for £34 per person are available. Travel duration is 8h 5m
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BlaBlaCar5h 10m020:10Frankfurt am Main Airport01:20Prague0EconomyA Car from BlaBlaCar goes from , Frankfurt am Main Airport (Germany) at 03/07/2025 20:10:00 to , Prague (Czech Republic) arriving at 04/07/2025 01:20:00. 50 Economy ticket for £35 per person are available. Travel duration is 5h 10m
Cheapest Buses Thursday
Cheapest Carpool Thursday
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Condor1h 0m006:50Frankfurt am Main AirportFrankfurt am Main Airport07:50Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 04/07/2025 06:50:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 04/07/2025 07:50:00. 50 Economy ticket for £87 per person are available. Travel duration is 1h 0m
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Condor1h 0m014:50Frankfurt am Main AirportFrankfurt am Main Airport15:50Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 04/07/2025 14:50:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 04/07/2025 15:50:00. 50 Economy ticket for £87 per person are available. Travel duration is 1h 0m
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Lufthansa1h 0m022:15Frankfurt am Main AirportFrankfurt am Main Airport23:15Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 04/07/2025 22:15:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 04/07/2025 23:15:00. 50 Economy ticket for £171 per person are available. Travel duration is 1h 0m
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Lufthansa1h 0m008:40Frankfurt am Main AirportFrankfurt am Main Airport09:40Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 04/07/2025 08:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 04/07/2025 09:40:00. 50 Economy ticket for £173 per person are available. Travel duration is 1h 0m
Cheapest Flights Friday
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RegioJet6h 45m022:00Frankfurt am Main AirportFrankfurt am Main Airport04:45PragueTrain station Wilsonova0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 05/07/2025 22:00:00 to Train station Wilsonova, Prague (Czech Republic) arriving at 06/07/2025 04:45:00. 50 Economy ticket for £29 per person are available. Travel duration is 6h 45m
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RegioJet6h 48m022:00Frankfurt am Main AirportFrankfurt am Main Airport04:48PragueÚAN Florenc0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 05/07/2025 22:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 06/07/2025 04:48:00. 50 Economy ticket for £29 per person are available. Travel duration is 6h 48m
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FlixBus10h 45m005:15MainzCentral Station16:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 05/07/2025 05:15:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 05/07/2025 16:00:00. 50 Economy ticket for £35 per person are available. Travel duration is 10h 45m
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FlixBus10h 25m005:15MainzCentral Station15:40PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 05/07/2025 05:15:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 05/07/2025 15:40:00. 50 Economy ticket for £35 per person are available. Travel duration is 10h 25m
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BlaBlaCar5h 10m010:00Frankfurt am Main Airport15:10Prague0EconomyA Car from BlaBlaCar goes from , Frankfurt am Main Airport (Germany) at 05/07/2025 10:00:00 to , Prague (Czech Republic) arriving at 05/07/2025 15:10:00. 50 Economy ticket for £40 per person are available. Travel duration is 5h 10m
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Condor1h 0m014:50Frankfurt am Main AirportFrankfurt am Main Airport15:50Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 05/07/2025 14:50:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 05/07/2025 15:50:00. 50 Economy ticket for £105 per person are available. Travel duration is 1h 0m
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Condor1h 0m006:50Frankfurt am Main AirportFrankfurt am Main Airport07:50Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 05/07/2025 06:50:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 05/07/2025 07:50:00. 50 Economy ticket for £138 per person are available. Travel duration is 1h 0m
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Lufthansa1h 0m009:55Frankfurt am Main AirportFrankfurt am Main Airport10:55Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 05/07/2025 09:55:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 05/07/2025 10:55:00. 50 Economy ticket for £183 per person are available. Travel duration is 1h 0m
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Lufthansa1h 0m012:55Frankfurt am Main AirportFrankfurt am Main Airport13:55Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 05/07/2025 12:55:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 05/07/2025 13:55:00. 50 Economy ticket for £183 per person are available. Travel duration is 1h 0m
Cheapest Buses Saturday
Cheapest Carpool Saturday
Cheapest Flights Saturday
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FlixBus11h 10m023:30MainzCentral Station10:40PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 06/07/2025 23:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 07/07/2025 10:40:00. 50 Economy ticket for £33 per person are available. Travel duration is 11h 10m
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FlixBus10h 45m005:15MainzCentral Station16:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 06/07/2025 05:15:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 06/07/2025 16:00:00. 50 Economy ticket for £36 per person are available. Travel duration is 10h 45m
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FlixBus10h 25m005:15MainzCentral Station15:40PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 06/07/2025 05:15:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 06/07/2025 15:40:00. 50 Economy ticket for £36 per person are available. Travel duration is 10h 25m
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FlixBus8h 30m010:40Frankfurt am Main AirportFrankfurt am Main Airport19:10PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 06/07/2025 10:40:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 06/07/2025 19:10:00. 50 Economy ticket for £37 per person are available. Travel duration is 8h 30m
Cheapest Buses Sunday
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RegioJet6h 48m022:00Frankfurt am Main AirportFrankfurt am Main Airport04:48PragueÚAN Florenc0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 07/07/2025 22:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 08/07/2025 04:48:00. 50 Economy ticket for £26 per person are available. Travel duration is 6h 48m
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RegioJet6h 45m022:00Frankfurt am Main AirportFrankfurt am Main Airport04:45PragueTrain station Wilsonova0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 07/07/2025 22:00:00 to Train station Wilsonova, Prague (Czech Republic) arriving at 08/07/2025 04:45:00. 50 Economy ticket for £26 per person are available. Travel duration is 6h 45m
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Condor1h 0m006:50Frankfurt am Main AirportFrankfurt am Main Airport07:50Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 07/07/2025 06:50:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 07/07/2025 07:50:00. 50 Economy ticket for £98 per person are available. Travel duration is 1h 0m
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Condor1h 0m014:50Frankfurt am Main AirportFrankfurt am Main Airport15:50Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 07/07/2025 14:50:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 07/07/2025 15:50:00. 50 Economy ticket for £111 per person are available. Travel duration is 1h 0m
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Lufthansa1h 0m008:40Frankfurt am Main AirportFrankfurt am Main Airport09:40Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 07/07/2025 08:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 07/07/2025 09:40:00. 50 Economy ticket for £162 per person are available. Travel duration is 1h 0m
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Lufthansa1h 0m016:50Frankfurt am Main AirportFrankfurt am Main Airport17:50Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 07/07/2025 16:50:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 07/07/2025 17:50:00. 50 Economy ticket for £162 per person are available. Travel duration is 1h 0m
Cheapest Buses Monday
Cheapest Flights Monday
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RegioJet6h 45m022:00Frankfurt am Main AirportFrankfurt am Main Airport04:45PragueTrain station Wilsonova0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/07/2025 22:00:00 to Train station Wilsonova, Prague (Czech Republic) arriving at 09/07/2025 04:45:00. 50 Economy ticket for £22 per person are available. Travel duration is 6h 45m
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FlixBus8h 30m010:40Frankfurt am Main AirportFrankfurt am Main Airport19:10PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/07/2025 10:40:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 08/07/2025 19:10:00. 50 Economy ticket for £28 per person are available. Travel duration is 8h 30m
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FlixBus8h 55m010:40Frankfurt am Main AirportFrankfurt am Main Airport19:35PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/07/2025 10:40:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 08/07/2025 19:35:00. 50 Economy ticket for £28 per person are available. Travel duration is 8h 55m
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FlixBus10h 45m005:15MainzCentral Station16:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 08/07/2025 05:15:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 08/07/2025 16:00:00. 50 Economy ticket for £29 per person are available. Travel duration is 10h 45m
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Condor1h 0m006:50Frankfurt am Main AirportFrankfurt am Main Airport07:50Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/07/2025 06:50:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/07/2025 07:50:00. 50 Economy ticket for £89 per person are available. Travel duration is 1h 0m
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Condor1h 0m014:50Frankfurt am Main AirportFrankfurt am Main Airport15:50Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/07/2025 14:50:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/07/2025 15:50:00. 50 Economy ticket for £145 per person are available. Travel duration is 1h 0m
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Lufthansa1h 0m008:40Frankfurt am Main AirportFrankfurt am Main Airport09:40Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/07/2025 08:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/07/2025 09:40:00. 50 Economy ticket for £158 per person are available. Travel duration is 1h 0m
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Lufthansa1h 0m009:55Frankfurt am Main AirportFrankfurt am Main Airport10:55Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/07/2025 09:55:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/07/2025 10:55:00. 50 Economy ticket for £158 per person are available. Travel duration is 1h 0m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
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FlixBus8h 30m010:40Frankfurt am Main AirportFrankfurt am Main Airport19:10PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 09/07/2025 10:40:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 09/07/2025 19:10:00. 50 Economy ticket for £30 per person are available. Travel duration is 8h 30m
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FlixBus8h 55m010:40Frankfurt am Main AirportFrankfurt am Main Airport19:35PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 09/07/2025 10:40:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 09/07/2025 19:35:00. 50 Economy ticket for £30 per person are available. Travel duration is 8h 55m
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FlixBus10h 45m005:15MainzCentral Station16:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 09/07/2025 05:15:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 09/07/2025 16:00:00. 50 Economy ticket for £32 per person are available. Travel duration is 10h 45m
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FlixBus10h 25m005:15MainzCentral Station15:40PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 09/07/2025 05:15:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 09/07/2025 15:40:00. 50 Economy ticket for £32 per person are available. Travel duration is 10h 25m
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Condor1h 0m006:50Frankfurt am Main AirportFrankfurt am Main Airport07:50Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 09/07/2025 06:50:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 09/07/2025 07:50:00. 50 Economy ticket for £92 per person are available. Travel duration is 1h 0m
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Condor1h 0m014:50Frankfurt am Main AirportFrankfurt am Main Airport15:50Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 09/07/2025 14:50:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 09/07/2025 15:50:00. 50 Economy ticket for £92 per person are available. Travel duration is 1h 0m
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Lufthansa1h 0m008:40Frankfurt am Main AirportFrankfurt am Main Airport09:40Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 09/07/2025 08:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 09/07/2025 09:40:00. 50 Economy ticket for £131 per person are available. Travel duration is 1h 0m
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Lufthansa1h 0m009:50Frankfurt am Main AirportFrankfurt am Main Airport10:50Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 09/07/2025 09:50:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 09/07/2025 10:50:00. 50 Economy ticket for £131 per person are available. Travel duration is 1h 0m
Cheapest Buses Wednesday
Cheapest Flights Wednesday
What are the fastest trips from Mainz to Prague?
You can get to Prague from Mainz in just 1h 0m with a Flight from Condor. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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BlaBlaCar5h 10m020:10Frankfurt am Main Airport01:20Prague0EconomyA Car from BlaBlaCar goes from , Frankfurt am Main Airport (Germany) at 03/07/2025 20:10:00 to , Prague (Czech Republic) arriving at 04/07/2025 01:20:00. 50 Economy ticket for £35 per person are available. Travel duration is 5h 10m
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RegioJet6h 45m022:00Frankfurt am Main AirportFrankfurt am Main Airport04:45PragueTrain station Wilsonova0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 03/07/2025 22:00:00 to Train station Wilsonova, Prague (Czech Republic) arriving at 04/07/2025 04:45:00. 50 Economy ticket for £26 per person are available. Travel duration is 6h 45m
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RegioJet6h 48m022:00Frankfurt am Main AirportFrankfurt am Main Airport04:48PragueÚAN Florenc0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 03/07/2025 22:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 04/07/2025 04:48:00. 50 Economy ticket for £26 per person are available. Travel duration is 6h 48m
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FlixBus8h 5m016:00MainzCentral Station00:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 03/07/2025 16:00:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 04/07/2025 00:05:00. 50 Economy ticket for £34 per person are available. Travel duration is 8h 5m
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FlixBus8h 25m016:00MainzCentral Station00:25PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 03/07/2025 16:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 04/07/2025 00:25:00. 50 Economy ticket for £34 per person are available. Travel duration is 8h 25m
Fastest Carpool Thursday
Fastest Buses Thursday
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Condor1h 0m006:50Frankfurt am Main AirportFrankfurt am Main Airport07:50Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 04/07/2025 06:50:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 04/07/2025 07:50:00. 50 Economy ticket for £87 per person are available. Travel duration is 1h 0m
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Condor1h 0m014:50Frankfurt am Main AirportFrankfurt am Main Airport15:50Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 04/07/2025 14:50:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 04/07/2025 15:50:00. 50 Economy ticket for £87 per person are available. Travel duration is 1h 0m
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Lufthansa1h 0m022:15Frankfurt am Main AirportFrankfurt am Main Airport23:15Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 04/07/2025 22:15:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 04/07/2025 23:15:00. 50 Economy ticket for £171 per person are available. Travel duration is 1h 0m
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Lufthansa1h 0m008:40Frankfurt am Main AirportFrankfurt am Main Airport09:40Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 04/07/2025 08:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 04/07/2025 09:40:00. 50 Economy ticket for £173 per person are available. Travel duration is 1h 0m
Fastest Flights Friday
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Condor1h 0m014:50Frankfurt am Main AirportFrankfurt am Main Airport15:50Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 05/07/2025 14:50:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 05/07/2025 15:50:00. 50 Economy ticket for £105 per person are available. Travel duration is 1h 0m
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Condor1h 0m006:50Frankfurt am Main AirportFrankfurt am Main Airport07:50Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 05/07/2025 06:50:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 05/07/2025 07:50:00. 50 Economy ticket for £138 per person are available. Travel duration is 1h 0m
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Lufthansa1h 0m009:55Frankfurt am Main AirportFrankfurt am Main Airport10:55Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 05/07/2025 09:55:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 05/07/2025 10:55:00. 50 Economy ticket for £183 per person are available. Travel duration is 1h 0m
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Lufthansa1h 0m012:55Frankfurt am Main AirportFrankfurt am Main Airport13:55Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 05/07/2025 12:55:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 05/07/2025 13:55:00. 50 Economy ticket for £183 per person are available. Travel duration is 1h 0m
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BlaBlaCar5h 10m010:00Frankfurt am Main Airport15:10Prague0EconomyA Car from BlaBlaCar goes from , Frankfurt am Main Airport (Germany) at 05/07/2025 10:00:00 to , Prague (Czech Republic) arriving at 05/07/2025 15:10:00. 50 Economy ticket for £40 per person are available. Travel duration is 5h 10m
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RegioJet6h 45m022:00Frankfurt am Main AirportFrankfurt am Main Airport04:45PragueTrain station Wilsonova0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 05/07/2025 22:00:00 to Train station Wilsonova, Prague (Czech Republic) arriving at 06/07/2025 04:45:00. 50 Economy ticket for £29 per person are available. Travel duration is 6h 45m
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RegioJet6h 48m022:00Frankfurt am Main AirportFrankfurt am Main Airport04:48PragueÚAN Florenc0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 05/07/2025 22:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 06/07/2025 04:48:00. 50 Economy ticket for £29 per person are available. Travel duration is 6h 48m
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FlixBus8h 30m010:40Frankfurt am Main AirportFrankfurt am Main Airport19:10PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 05/07/2025 10:40:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 05/07/2025 19:10:00. 50 Economy ticket for £36 per person are available. Travel duration is 8h 30m
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FlixBus10h 25m005:15MainzCentral Station15:40PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 05/07/2025 05:15:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 05/07/2025 15:40:00. 50 Economy ticket for £35 per person are available. Travel duration is 10h 25m
Fastest Flights Saturday
Fastest Carpool Saturday
Fastest Buses Saturday
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FlixBus8h 30m010:40Frankfurt am Main AirportFrankfurt am Main Airport19:10PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 06/07/2025 10:40:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 06/07/2025 19:10:00. 50 Economy ticket for £37 per person are available. Travel duration is 8h 30m
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FlixBus8h 55m010:40Frankfurt am Main AirportFrankfurt am Main Airport19:35PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 06/07/2025 10:40:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 06/07/2025 19:35:00. 50 Economy ticket for £37 per person are available. Travel duration is 8h 55m
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FlixBus10h 25m005:15MainzCentral Station15:40PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 06/07/2025 05:15:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 06/07/2025 15:40:00. 50 Economy ticket for £36 per person are available. Travel duration is 10h 25m
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FlixBus10h 45m005:15MainzCentral Station16:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 06/07/2025 05:15:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 06/07/2025 16:00:00. 50 Economy ticket for £36 per person are available. Travel duration is 10h 45m
Fastest Buses Sunday
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Condor1h 0m006:50Frankfurt am Main AirportFrankfurt am Main Airport07:50Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 07/07/2025 06:50:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 07/07/2025 07:50:00. 50 Economy ticket for £98 per person are available. Travel duration is 1h 0m
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Condor1h 0m014:50Frankfurt am Main AirportFrankfurt am Main Airport15:50Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 07/07/2025 14:50:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 07/07/2025 15:50:00. 50 Economy ticket for £111 per person are available. Travel duration is 1h 0m
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Lufthansa1h 0m008:40Frankfurt am Main AirportFrankfurt am Main Airport09:40Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 07/07/2025 08:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 07/07/2025 09:40:00. 50 Economy ticket for £162 per person are available. Travel duration is 1h 0m
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Lufthansa1h 0m016:50Frankfurt am Main AirportFrankfurt am Main Airport17:50Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 07/07/2025 16:50:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 07/07/2025 17:50:00. 50 Economy ticket for £162 per person are available. Travel duration is 1h 0m
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RegioJet6h 45m022:00Frankfurt am Main AirportFrankfurt am Main Airport04:45PragueTrain station Wilsonova0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 07/07/2025 22:00:00 to Train station Wilsonova, Prague (Czech Republic) arriving at 08/07/2025 04:45:00. 50 Economy ticket for £26 per person are available. Travel duration is 6h 45m
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RegioJet6h 48m022:00Frankfurt am Main AirportFrankfurt am Main Airport04:48PragueÚAN Florenc0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 07/07/2025 22:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 08/07/2025 04:48:00. 50 Economy ticket for £26 per person are available. Travel duration is 6h 48m
Fastest Flights Monday
Fastest Buses Monday
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Condor1h 0m006:50Frankfurt am Main AirportFrankfurt am Main Airport07:50Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/07/2025 06:50:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/07/2025 07:50:00. 50 Economy ticket for £89 per person are available. Travel duration is 1h 0m
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Condor1h 0m014:50Frankfurt am Main AirportFrankfurt am Main Airport15:50Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/07/2025 14:50:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/07/2025 15:50:00. 50 Economy ticket for £145 per person are available. Travel duration is 1h 0m
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Lufthansa1h 0m008:40Frankfurt am Main AirportFrankfurt am Main Airport09:40Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/07/2025 08:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/07/2025 09:40:00. 50 Economy ticket for £158 per person are available. Travel duration is 1h 0m
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Lufthansa1h 0m009:55Frankfurt am Main AirportFrankfurt am Main Airport10:55Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/07/2025 09:55:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/07/2025 10:55:00. 50 Economy ticket for £158 per person are available. Travel duration is 1h 0m
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RegioJet6h 45m022:00Frankfurt am Main AirportFrankfurt am Main Airport04:45PragueTrain station Wilsonova0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/07/2025 22:00:00 to Train station Wilsonova, Prague (Czech Republic) arriving at 09/07/2025 04:45:00. 50 Economy ticket for £22 per person are available. Travel duration is 6h 45m
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FlixBus8h 30m010:40Frankfurt am Main AirportFrankfurt am Main Airport19:10PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/07/2025 10:40:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 08/07/2025 19:10:00. 50 Economy ticket for £28 per person are available. Travel duration is 8h 30m
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FlixBus8h 55m010:40Frankfurt am Main AirportFrankfurt am Main Airport19:35PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/07/2025 10:40:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 08/07/2025 19:35:00. 50 Economy ticket for £28 per person are available. Travel duration is 8h 55m
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FlixBus10h 45m005:15MainzCentral Station16:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 08/07/2025 05:15:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 08/07/2025 16:00:00. 50 Economy ticket for £29 per person are available. Travel duration is 10h 45m
Fastest Flights Tuesday
Fastest Buses Tuesday
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Condor1h 0m006:50Frankfurt am Main AirportFrankfurt am Main Airport07:50Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 09/07/2025 06:50:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 09/07/2025 07:50:00. 50 Economy ticket for £92 per person are available. Travel duration is 1h 0m
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Condor1h 0m014:50Frankfurt am Main AirportFrankfurt am Main Airport15:50Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 09/07/2025 14:50:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 09/07/2025 15:50:00. 50 Economy ticket for £92 per person are available. Travel duration is 1h 0m
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Lufthansa1h 0m008:40Frankfurt am Main AirportFrankfurt am Main Airport09:40Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 09/07/2025 08:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 09/07/2025 09:40:00. 50 Economy ticket for £131 per person are available. Travel duration is 1h 0m
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Lufthansa1h 0m009:50Frankfurt am Main AirportFrankfurt am Main Airport10:50Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 09/07/2025 09:50:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 09/07/2025 10:50:00. 50 Economy ticket for £131 per person are available. Travel duration is 1h 0m
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FlixBus8h 30m010:40Frankfurt am Main AirportFrankfurt am Main Airport19:10PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 09/07/2025 10:40:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 09/07/2025 19:10:00. 50 Economy ticket for £30 per person are available. Travel duration is 8h 30m
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FlixBus8h 55m010:40Frankfurt am Main AirportFrankfurt am Main Airport19:35PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 09/07/2025 10:40:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 09/07/2025 19:35:00. 50 Economy ticket for £30 per person are available. Travel duration is 8h 55m
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FlixBus9h 35m001:15Frankfurt am Main AirportFrankfurt am Main Airport10:50PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 09/07/2025 01:15:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 09/07/2025 10:50:00. 50 Economy ticket for £33 per person are available. Travel duration is 9h 35m
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FlixBus10h 25m005:15MainzCentral Station15:40PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 09/07/2025 05:15:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 09/07/2025 15:40:00. 50 Economy ticket for £32 per person are available. Travel duration is 10h 25m
Fastest Flights Wednesday
Fastest Buses Wednesday
Here you will find all operators and timetables for a
Bus from Mainz to Prague
What are the most popular stations in Mainz and Prague?
In Mainz, you will usually depart from Central Station, Central Bus Station or Laubenheim Train Station, while in Prague you will be arriving at ÚAN Florenc, Train station Wilsonova or Holešovice zastávka Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Prague from Mainz? With 7 connections between 1 Carpool, Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Mainz and Prague, you can pay as low as £22 with a Bus from RegioJet.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Condor: you will get to Prague in just 1h 0m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Mainz and Prague are FlixBus, Lufthansa and Condor, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Mainz and Prague is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Budenheim or to Horoměřice, and look at flights from Frankfurt am Main Airport, and landing at Prague Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Mainz to Prague?
The most popular companies between Mainz and Prague, are FlixBus, Lufthansa and Condor. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus and RegioJet
Airlines: Lufthansa and Condor
All you need to know when you travel from Mainz to Prague
Check all information on comfort and services on all modes of transports from Mainz to Prague. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Mainz to Prague
How can I reach Prague from Mainz?
Every day, there are on average 7 connections between Carpool, Bus and Flight, with which you can get to Prague from Mainz.
How far is Prague from Mainz?
The distance between Mainz and Prague is 442.1 km.
What is the most ecofriendly mode of transport between Mainz and Prague?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 12 kgs of CO2, a train 15 kgs, a car 75 kgs, and a flight 109 kgs.
What is the cheapest mode of transport from Mainz to Prague?
You can get to Prague with just £22 by taking a Bus from RegioJet.
What is the fastest way to get from Mainz to Prague?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Prague in just 1h 0m with a Flight from Condor.
More routes to Mainz and to Prague
Looking for more options? Here you can see the most popular routes to Mainz and to Prague. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Mainz
- Berlin to Mainz
- Cologne/Bonn Airport to Mainz
- Dresden to Mainz
- Frankfurt am Main Airport to Mainz
- Frankfurt Hahn Airport to Mainz
- Freiburg to Mainz
- Heidelberg to Mainz
- Kaiserslautern to Mainz
- Katowice to Mainz
- Koblenz to Mainz
- Munich to Mainz
- Passau to Mainz
- Saarbruecken to Mainz
- Simmern (Hunsrück) to Mainz
- Trips to Prague
- Amsterdam to Prague
- Berlin to Prague
- Bratislava to Prague
- Brno to Prague
- Dresden to Prague
- Dusseldorf to Prague
- Frankfurt am Main to Prague
- Humpolec to Prague
- Jihlava to Prague
- Karlovy Vary to Prague
- Krakow to Prague
- Leipzig to Prague
- London to Prague
- Lyon to Prague
- Milan to Prague
- Minsk to Prague
- Munich Airport to Prague
- Munich to Prague
- Nuremberg to Prague
- Paris to Prague
- Rome to Prague
- Vienna to Prague
- Zlín to Prague
- Zurich to Prague