What is the best way to travel from Mainz to Prague?
Looking for a trip? Check and compare all the available Buses and Flights to Prague from Mainz. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
What is the cheapest way to reach Prague from Mainz?
You can reach Prague with just £23 by taking a Bus from RegioJet, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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FlixBus7h 25m023:30Frankfurt am Main AirportFrankfurt am Main Airport06:55PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 13/12/2025 23:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 14/12/2025 06:55:00. 50 Economy ticket for £27 per person are available. Travel duration is 7h 25m
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FlixBus10h 45m005:15MainzCentral Station16:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 13/12/2025 05:15:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 13/12/2025 16:00:00. 50 Economy ticket for £32 per person are available. Travel duration is 10h 45m
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FlixBus8h 25m016:00MainzCentral Station00:25PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 13/12/2025 16:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 14/12/2025 00:25:00. 50 Economy ticket for £32 per person are available. Travel duration is 8h 25m
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FlixBus10h 25m005:15MainzCentral Station15:40PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 13/12/2025 05:15:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 13/12/2025 15:40:00. 50 Economy ticket for £32 per person are available. Travel duration is 10h 25m
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FlixBus11h 10m023:30MainzCentral Station10:40PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 13/12/2025 23:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 14/12/2025 10:40:00. 50 Economy ticket for £32 per person are available. Travel duration is 11h 10m
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Condor1h 0m009:20Frankfurt am Main AirportFrankfurt am Main Airport10:20Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 13/12/2025 09:20:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 13/12/2025 10:20:00. 50 Economy ticket for £100 per person are available. Travel duration is 1h 0m
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Condor1h 0m014:15Frankfurt am Main AirportFrankfurt am Main Airport15:15Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 13/12/2025 14:15:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 13/12/2025 15:15:00. 50 Economy ticket for £100 per person are available. Travel duration is 1h 0m
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Air Dolomiti1h 5m008:45Frankfurt am Main AirportFrankfurt am Main Airport09:50Prague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 13/12/2025 08:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 13/12/2025 09:50:00. 50 Economy ticket for £116 per person are available. Travel duration is 1h 5m
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Air Dolomiti1h 5m017:10Frankfurt am Main AirportFrankfurt am Main Airport18:15Prague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 13/12/2025 17:10:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 13/12/2025 18:15:00. 50 Economy ticket for £116 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m013:00Frankfurt am Main AirportFrankfurt am Main Airport14:05Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 13/12/2025 13:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 13/12/2025 14:05:00. 50 Economy ticket for £116 per person are available. Travel duration is 1h 5m
Cheapest Buses Saturday
Cheapest Flights Saturday
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RegioJet6h 48m022:00Frankfurt am Main AirportFrankfurt am Main Airport04:48PragueÚAN Florenc0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 14/12/2025 22:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 15/12/2025 04:48:00. 50 Economy ticket for £23 per person are available. Travel duration is 6h 48m
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RegioJet6h 45m022:00Frankfurt am Main AirportFrankfurt am Main Airport04:45PragueTrain station Wilsonova0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 14/12/2025 22:00:00 to Train station Wilsonova, Prague (Czech Republic) arriving at 15/12/2025 04:45:00. 50 Economy ticket for £26 per person are available. Travel duration is 6h 45m
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Condor1h 0m009:20Frankfurt am Main AirportFrankfurt am Main Airport10:20Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 14/12/2025 09:20:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 14/12/2025 10:20:00. 50 Economy ticket for £81 per person are available. Travel duration is 1h 0m
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Condor1h 0m020:10Frankfurt am Main AirportFrankfurt am Main Airport21:10Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 14/12/2025 20:10:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 14/12/2025 21:10:00. 50 Economy ticket for £97 per person are available. Travel duration is 1h 0m
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Lufthansa1h 5m010:25Frankfurt am Main AirportFrankfurt am Main Airport11:30Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 14/12/2025 10:25:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 14/12/2025 11:30:00. 50 Economy ticket for £197 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m021:10Frankfurt am Main AirportFrankfurt am Main Airport22:15Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 14/12/2025 21:10:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 14/12/2025 22:15:00. 50 Economy ticket for £221 per person are available. Travel duration is 1h 5m
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Air Dolomiti1h 5m017:00Frankfurt am Main AirportFrankfurt am Main Airport18:05Prague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 14/12/2025 17:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 14/12/2025 18:05:00. 50 Economy ticket for £224 per person are available. Travel duration is 1h 5m
Cheapest Buses Sunday
Cheapest Flights Sunday
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RegioJet6h 45m022:00Frankfurt am Main AirportFrankfurt am Main Airport04:45PragueTrain station Wilsonova0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 15/12/2025 22:00:00 to Train station Wilsonova, Prague (Czech Republic) arriving at 16/12/2025 04:45:00. 50 Economy ticket for £23 per person are available. Travel duration is 6h 45m
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RegioJet6h 48m022:00Frankfurt am Main AirportFrankfurt am Main Airport04:48PragueÚAN Florenc0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 15/12/2025 22:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 16/12/2025 04:48:00. 50 Economy ticket for £23 per person are available. Travel duration is 6h 48m
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FlixBus7h 25m023:30Frankfurt am Main AirportFrankfurt am Main Airport06:55PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 15/12/2025 23:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 16/12/2025 06:55:00. 50 Economy ticket for £29 per person are available. Travel duration is 7h 25m
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FlixBus9h 25m023:30Frankfurt am Main AirportFrankfurt am Main Airport08:55PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 15/12/2025 23:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 16/12/2025 08:55:00. 50 Economy ticket for £31 per person are available. Travel duration is 9h 25m
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FlixBus10h 15m001:15Frankfurt am Main AirportFrankfurt am Main Airport11:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 15/12/2025 01:15:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 15/12/2025 11:30:00. 50 Economy ticket for £31 per person are available. Travel duration is 10h 15m
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Condor1h 0m014:15Frankfurt am Main AirportFrankfurt am Main Airport15:15Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 15/12/2025 14:15:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 15/12/2025 15:15:00. 50 Economy ticket for £94 per person are available. Travel duration is 1h 0m
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Lufthansa1h 5m008:45Frankfurt am Main AirportFrankfurt am Main Airport09:50Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 15/12/2025 08:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 15/12/2025 09:50:00. 50 Economy ticket for £189 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m010:05Frankfurt am Main AirportFrankfurt am Main Airport11:10Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 15/12/2025 10:05:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 15/12/2025 11:10:00. 50 Economy ticket for £189 per person are available. Travel duration is 1h 5m
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Air Dolomiti1h 5m017:10Frankfurt am Main AirportFrankfurt am Main Airport18:15Prague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 15/12/2025 17:10:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 15/12/2025 18:15:00. 50 Economy ticket for £189 per person are available. Travel duration is 1h 5m
Cheapest Buses Monday
Cheapest Flights Monday
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FlixBus10h 45m005:15MainzCentral Station16:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 16/12/2025 05:15:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 16/12/2025 16:00:00. 50 Economy ticket for £34 per person are available. Travel duration is 10h 45m
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FlixBus10h 25m005:15MainzCentral Station15:40PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 16/12/2025 05:15:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 16/12/2025 15:40:00. 50 Economy ticket for £34 per person are available. Travel duration is 10h 25m
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FlixBus11h 10m023:30MainzCentral Station10:40PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 16/12/2025 23:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 17/12/2025 10:40:00. 50 Economy ticket for £34 per person are available. Travel duration is 11h 10m
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FlixBus8h 25m016:00MainzCentral Station00:25PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 16/12/2025 16:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 17/12/2025 00:25:00. 50 Economy ticket for £35 per person are available. Travel duration is 8h 25m
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FlixBus8h 5m016:00MainzCentral Station00:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 16/12/2025 16:00:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 17/12/2025 00:05:00. 50 Economy ticket for £35 per person are available. Travel duration is 8h 5m
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Condor1h 0m009:20Frankfurt am Main AirportFrankfurt am Main Airport10:20Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 16/12/2025 09:20:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 16/12/2025 10:20:00. 50 Economy ticket for £71 per person are available. Travel duration is 1h 0m
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Condor1h 0m014:15Frankfurt am Main AirportFrankfurt am Main Airport15:15Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 16/12/2025 14:15:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 16/12/2025 15:15:00. 50 Economy ticket for £79 per person are available. Travel duration is 1h 0m
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Air Dolomiti1h 5m008:30Frankfurt am Main AirportFrankfurt am Main Airport09:35Prague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 16/12/2025 08:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 16/12/2025 09:35:00. 50 Economy ticket for £112 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m010:00Frankfurt am Main AirportFrankfurt am Main Airport11:05Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 16/12/2025 10:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 16/12/2025 11:05:00. 50 Economy ticket for £135 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m013:10Frankfurt am Main AirportFrankfurt am Main Airport14:15Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 16/12/2025 13:10:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 16/12/2025 14:15:00. 50 Economy ticket for £135 per person are available. Travel duration is 1h 5m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
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Condor1h 0m009:20Frankfurt am Main AirportFrankfurt am Main Airport10:20Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 17/12/2025 09:20:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 17/12/2025 10:20:00. 50 Economy ticket for £79 per person are available. Travel duration is 1h 0m
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Condor1h 0m020:10Frankfurt am Main AirportFrankfurt am Main Airport21:10Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 17/12/2025 20:10:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 17/12/2025 21:10:00. 50 Economy ticket for £79 per person are available. Travel duration is 1h 0m
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Air Dolomiti1h 5m008:30Frankfurt am Main AirportFrankfurt am Main Airport09:35Prague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 17/12/2025 08:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 17/12/2025 09:35:00. 50 Economy ticket for £185 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m021:20Frankfurt am Main AirportFrankfurt am Main Airport22:25Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 17/12/2025 21:20:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 17/12/2025 22:25:00. 50 Economy ticket for £219 per person are available. Travel duration is 1h 5m
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Air Dolomiti1h 5m017:10Frankfurt am Main AirportFrankfurt am Main Airport18:15Prague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 17/12/2025 17:10:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 17/12/2025 18:15:00. 50 Economy ticket for £224 per person are available. Travel duration is 1h 5m
Cheapest Flights Wednesday
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FlixBus8h 55m010:40Frankfurt am Main AirportFrankfurt am Main Airport19:35PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 18/12/2025 10:40:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 18/12/2025 19:35:00. 50 Economy ticket for £38 per person are available. Travel duration is 8h 55m
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FlixBus8h 30m010:40Frankfurt am Main AirportFrankfurt am Main Airport19:10PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 18/12/2025 10:40:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 18/12/2025 19:10:00. 50 Economy ticket for £38 per person are available. Travel duration is 8h 30m
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FlixBus8h 55m004:15Frankfurt am Main AirportFrankfurt am Main Airport13:10PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 18/12/2025 04:15:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 18/12/2025 13:10:00. 50 Economy ticket for £44 per person are available. Travel duration is 8h 55m
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FlixBus10h 15m001:15Frankfurt am Main AirportFrankfurt am Main Airport11:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 18/12/2025 01:15:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 18/12/2025 11:30:00. 50 Economy ticket for £44 per person are available. Travel duration is 10h 15m
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FlixBus9h 55m001:15Frankfurt am Main AirportFrankfurt am Main Airport11:10PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 18/12/2025 01:15:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 18/12/2025 11:10:00. 50 Economy ticket for £45 per person are available. Travel duration is 9h 55m
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Condor15h 35m016:35Frankfurt am Main AirportFrankfurt am Main Airport08:10Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 18/12/2025 16:35:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 19/12/2025 08:10:00. 50 Economy ticket for £88 per person are available. Travel duration is 15h 35m
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Condor1h 0m020:10Frankfurt am Main AirportFrankfurt am Main Airport21:10Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 18/12/2025 20:10:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 18/12/2025 21:10:00. 50 Economy ticket for £89 per person are available. Travel duration is 1h 0m
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Lufthansa1h 5m010:00Frankfurt am Main AirportFrankfurt am Main Airport11:05Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 18/12/2025 10:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 18/12/2025 11:05:00. 50 Economy ticket for £182 per person are available. Travel duration is 1h 5m
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Air Dolomiti1h 5m008:40Frankfurt am Main AirportFrankfurt am Main Airport09:45Prague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 18/12/2025 08:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 18/12/2025 09:45:00. 50 Economy ticket for £187 per person are available. Travel duration is 1h 5m
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Air Dolomiti1h 5m017:00Frankfurt am Main AirportFrankfurt am Main Airport18:05Prague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 18/12/2025 17:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 18/12/2025 18:05:00. 50 Economy ticket for £187 per person are available. Travel duration is 1h 5m
Cheapest Buses Thursday
Cheapest Flights Thursday
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FlixBus8h 35m000:20Frankfurt am Main AirportFrankfurt am Main Airport08:55PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 19/12/2025 00:20:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 19/12/2025 08:55:00. 50 Economy ticket for £61 per person are available. Travel duration is 8h 35m
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FlixBus9h 0m000:20Frankfurt am Main AirportFrankfurt am Main Airport09:20PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 19/12/2025 00:20:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 19/12/2025 09:20:00. 50 Economy ticket for £61 per person are available. Travel duration is 9h 0m
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FlixBus9h 55m001:15Frankfurt am Main AirportFrankfurt am Main Airport11:10PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 19/12/2025 01:15:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 19/12/2025 11:10:00. 50 Economy ticket for £61 per person are available. Travel duration is 9h 55m
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FlixBus9h 0m001:05Frankfurt am Main AirportFrankfurt am Main Airport10:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 19/12/2025 01:05:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 19/12/2025 10:05:00. 50 Economy ticket for £66 per person are available. Travel duration is 9h 0m
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FlixBus9h 30m001:05Frankfurt am Main AirportFrankfurt am Main Airport10:35PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 19/12/2025 01:05:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 19/12/2025 10:35:00. 50 Economy ticket for £66 per person are available. Travel duration is 9h 30m
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Condor1h 0m009:20Frankfurt am Main AirportFrankfurt am Main Airport10:20Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 19/12/2025 09:20:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 19/12/2025 10:20:00. 50 Economy ticket for £104 per person are available. Travel duration is 1h 0m
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Condor1h 0m020:10Frankfurt am Main AirportFrankfurt am Main Airport21:10Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 19/12/2025 20:10:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 19/12/2025 21:10:00. 50 Economy ticket for £150 per person are available. Travel duration is 1h 0m
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Air Dolomiti1h 5m008:30Frankfurt am Main AirportFrankfurt am Main Airport09:35Prague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 19/12/2025 08:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 19/12/2025 09:35:00. 50 Economy ticket for £188 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m010:10Frankfurt am Main AirportFrankfurt am Main Airport11:15Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 19/12/2025 10:10:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 19/12/2025 11:15:00. 50 Economy ticket for £210 per person are available. Travel duration is 1h 5m
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Air Dolomiti1h 5m017:00Frankfurt am Main AirportFrankfurt am Main Airport18:05Prague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 19/12/2025 17:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 19/12/2025 18:05:00. 50 Economy ticket for £224 per person are available. Travel duration is 1h 5m
Cheapest Buses Friday
Cheapest Flights Friday
What are the fastest trips from Mainz to Prague?
You can get to Prague from Mainz in just 1h 0m with a Flight from Condor. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Condor1h 0m009:20Frankfurt am Main AirportFrankfurt am Main Airport10:20Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 13/12/2025 09:20:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 13/12/2025 10:20:00. 50 Economy ticket for £100 per person are available. Travel duration is 1h 0m
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Condor1h 0m014:15Frankfurt am Main AirportFrankfurt am Main Airport15:15Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 13/12/2025 14:15:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 13/12/2025 15:15:00. 50 Economy ticket for £100 per person are available. Travel duration is 1h 0m
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Air Dolomiti1h 5m008:45Frankfurt am Main AirportFrankfurt am Main Airport09:50Prague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 13/12/2025 08:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 13/12/2025 09:50:00. 50 Economy ticket for £116 per person are available. Travel duration is 1h 5m
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Air Dolomiti1h 5m017:10Frankfurt am Main AirportFrankfurt am Main Airport18:15Prague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 13/12/2025 17:10:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 13/12/2025 18:15:00. 50 Economy ticket for £116 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m013:00Frankfurt am Main AirportFrankfurt am Main Airport14:05Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 13/12/2025 13:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 13/12/2025 14:05:00. 50 Economy ticket for £116 per person are available. Travel duration is 1h 5m
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FlixBus7h 25m023:30Frankfurt am Main AirportFrankfurt am Main Airport06:55PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 13/12/2025 23:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 14/12/2025 06:55:00. 50 Economy ticket for £27 per person are available. Travel duration is 7h 25m
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FlixBus8h 25m016:00MainzCentral Station00:25PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 13/12/2025 16:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 14/12/2025 00:25:00. 50 Economy ticket for £32 per person are available. Travel duration is 8h 25m
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FlixBus10h 25m005:15MainzCentral Station15:40PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 13/12/2025 05:15:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 13/12/2025 15:40:00. 50 Economy ticket for £32 per person are available. Travel duration is 10h 25m
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FlixBus10h 45m005:15MainzCentral Station16:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 13/12/2025 05:15:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 13/12/2025 16:00:00. 50 Economy ticket for £32 per person are available. Travel duration is 10h 45m
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FlixBus11h 10m023:30MainzCentral Station10:40PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 13/12/2025 23:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 14/12/2025 10:40:00. 50 Economy ticket for £32 per person are available. Travel duration is 11h 10m
Fastest Flights Saturday
Fastest Buses Saturday
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Condor1h 0m009:20Frankfurt am Main AirportFrankfurt am Main Airport10:20Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 14/12/2025 09:20:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 14/12/2025 10:20:00. 50 Economy ticket for £81 per person are available. Travel duration is 1h 0m
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Condor1h 0m020:10Frankfurt am Main AirportFrankfurt am Main Airport21:10Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 14/12/2025 20:10:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 14/12/2025 21:10:00. 50 Economy ticket for £97 per person are available. Travel duration is 1h 0m
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Lufthansa1h 5m010:25Frankfurt am Main AirportFrankfurt am Main Airport11:30Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 14/12/2025 10:25:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 14/12/2025 11:30:00. 50 Economy ticket for £197 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m021:10Frankfurt am Main AirportFrankfurt am Main Airport22:15Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 14/12/2025 21:10:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 14/12/2025 22:15:00. 50 Economy ticket for £221 per person are available. Travel duration is 1h 5m
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Air Dolomiti1h 5m017:00Frankfurt am Main AirportFrankfurt am Main Airport18:05Prague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 14/12/2025 17:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 14/12/2025 18:05:00. 50 Economy ticket for £224 per person are available. Travel duration is 1h 5m
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RegioJet6h 45m022:00Frankfurt am Main AirportFrankfurt am Main Airport04:45PragueTrain station Wilsonova0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 14/12/2025 22:00:00 to Train station Wilsonova, Prague (Czech Republic) arriving at 15/12/2025 04:45:00. 50 Economy ticket for £26 per person are available. Travel duration is 6h 45m
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RegioJet6h 48m022:00Frankfurt am Main AirportFrankfurt am Main Airport04:48PragueÚAN Florenc0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 14/12/2025 22:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 15/12/2025 04:48:00. 50 Economy ticket for £23 per person are available. Travel duration is 6h 48m
Fastest Flights Sunday
Fastest Buses Sunday
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Condor1h 0m014:15Frankfurt am Main AirportFrankfurt am Main Airport15:15Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 15/12/2025 14:15:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 15/12/2025 15:15:00. 50 Economy ticket for £94 per person are available. Travel duration is 1h 0m
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Lufthansa1h 5m008:45Frankfurt am Main AirportFrankfurt am Main Airport09:50Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 15/12/2025 08:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 15/12/2025 09:50:00. 50 Economy ticket for £189 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m010:05Frankfurt am Main AirportFrankfurt am Main Airport11:10Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 15/12/2025 10:05:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 15/12/2025 11:10:00. 50 Economy ticket for £189 per person are available. Travel duration is 1h 5m
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Air Dolomiti1h 5m017:10Frankfurt am Main AirportFrankfurt am Main Airport18:15Prague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 15/12/2025 17:10:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 15/12/2025 18:15:00. 50 Economy ticket for £189 per person are available. Travel duration is 1h 5m
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RegioJet6h 45m022:00Frankfurt am Main AirportFrankfurt am Main Airport04:45PragueTrain station Wilsonova0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 15/12/2025 22:00:00 to Train station Wilsonova, Prague (Czech Republic) arriving at 16/12/2025 04:45:00. 50 Economy ticket for £23 per person are available. Travel duration is 6h 45m
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RegioJet6h 48m022:00Frankfurt am Main AirportFrankfurt am Main Airport04:48PragueÚAN Florenc0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 15/12/2025 22:00:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 16/12/2025 04:48:00. 50 Economy ticket for £23 per person are available. Travel duration is 6h 48m
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FlixBus7h 25m023:30Frankfurt am Main AirportFrankfurt am Main Airport06:55PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 15/12/2025 23:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 16/12/2025 06:55:00. 50 Economy ticket for £29 per person are available. Travel duration is 7h 25m
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FlixBus9h 25m023:30Frankfurt am Main AirportFrankfurt am Main Airport08:55PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 15/12/2025 23:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 16/12/2025 08:55:00. 50 Economy ticket for £31 per person are available. Travel duration is 9h 25m
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FlixBus10h 15m001:15Frankfurt am Main AirportFrankfurt am Main Airport11:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 15/12/2025 01:15:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 15/12/2025 11:30:00. 50 Economy ticket for £31 per person are available. Travel duration is 10h 15m
Fastest Flights Monday
Fastest Buses Monday
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Condor1h 0m009:20Frankfurt am Main AirportFrankfurt am Main Airport10:20Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 16/12/2025 09:20:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 16/12/2025 10:20:00. 50 Economy ticket for £71 per person are available. Travel duration is 1h 0m
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Condor1h 0m014:15Frankfurt am Main AirportFrankfurt am Main Airport15:15Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 16/12/2025 14:15:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 16/12/2025 15:15:00. 50 Economy ticket for £79 per person are available. Travel duration is 1h 0m
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Air Dolomiti1h 5m008:30Frankfurt am Main AirportFrankfurt am Main Airport09:35Prague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 16/12/2025 08:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 16/12/2025 09:35:00. 50 Economy ticket for £112 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m010:00Frankfurt am Main AirportFrankfurt am Main Airport11:05Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 16/12/2025 10:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 16/12/2025 11:05:00. 50 Economy ticket for £135 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m013:10Frankfurt am Main AirportFrankfurt am Main Airport14:15Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 16/12/2025 13:10:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 16/12/2025 14:15:00. 50 Economy ticket for £135 per person are available. Travel duration is 1h 5m
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FlixBus8h 5m016:00MainzCentral Station00:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 16/12/2025 16:00:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 17/12/2025 00:05:00. 50 Economy ticket for £35 per person are available. Travel duration is 8h 5m
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FlixBus8h 25m016:00MainzCentral Station00:25PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 16/12/2025 16:00:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 17/12/2025 00:25:00. 50 Economy ticket for £35 per person are available. Travel duration is 8h 25m
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FlixBus10h 25m005:15MainzCentral Station15:40PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 16/12/2025 05:15:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 16/12/2025 15:40:00. 50 Economy ticket for £34 per person are available. Travel duration is 10h 25m
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FlixBus10h 45m005:15MainzCentral Station16:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 16/12/2025 05:15:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 16/12/2025 16:00:00. 50 Economy ticket for £34 per person are available. Travel duration is 10h 45m
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FlixBus11h 10m023:30MainzCentral Station10:40PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 16/12/2025 23:30:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 17/12/2025 10:40:00. 50 Economy ticket for £34 per person are available. Travel duration is 11h 10m
Fastest Flights Tuesday
Fastest Buses Tuesday
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Condor1h 0m009:20Frankfurt am Main AirportFrankfurt am Main Airport10:20Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 17/12/2025 09:20:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 17/12/2025 10:20:00. 50 Economy ticket for £79 per person are available. Travel duration is 1h 0m
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Condor1h 0m020:10Frankfurt am Main AirportFrankfurt am Main Airport21:10Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 17/12/2025 20:10:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 17/12/2025 21:10:00. 50 Economy ticket for £79 per person are available. Travel duration is 1h 0m
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Air Dolomiti1h 5m008:30Frankfurt am Main AirportFrankfurt am Main Airport09:35Prague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 17/12/2025 08:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 17/12/2025 09:35:00. 50 Economy ticket for £185 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m021:20Frankfurt am Main AirportFrankfurt am Main Airport22:25Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 17/12/2025 21:20:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 17/12/2025 22:25:00. 50 Economy ticket for £219 per person are available. Travel duration is 1h 5m
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Air Dolomiti1h 5m017:10Frankfurt am Main AirportFrankfurt am Main Airport18:15Prague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 17/12/2025 17:10:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 17/12/2025 18:15:00. 50 Economy ticket for £224 per person are available. Travel duration is 1h 5m
Fastest Flights Wednesday
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Condor1h 0m020:10Frankfurt am Main AirportFrankfurt am Main Airport21:10Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 18/12/2025 20:10:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 18/12/2025 21:10:00. 50 Economy ticket for £89 per person are available. Travel duration is 1h 0m
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Lufthansa1h 5m010:00Frankfurt am Main AirportFrankfurt am Main Airport11:05Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 18/12/2025 10:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 18/12/2025 11:05:00. 50 Economy ticket for £182 per person are available. Travel duration is 1h 5m
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Air Dolomiti1h 5m008:40Frankfurt am Main AirportFrankfurt am Main Airport09:45Prague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 18/12/2025 08:40:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 18/12/2025 09:45:00. 50 Economy ticket for £187 per person are available. Travel duration is 1h 5m
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Air Dolomiti1h 5m017:00Frankfurt am Main AirportFrankfurt am Main Airport18:05Prague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 18/12/2025 17:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 18/12/2025 18:05:00. 50 Economy ticket for £187 per person are available. Travel duration is 1h 5m
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Condor15h 35m016:35Frankfurt am Main AirportFrankfurt am Main Airport08:10Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 18/12/2025 16:35:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 19/12/2025 08:10:00. 50 Economy ticket for £88 per person are available. Travel duration is 15h 35m
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FlixBus8h 30m010:40Frankfurt am Main AirportFrankfurt am Main Airport19:10PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 18/12/2025 10:40:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 18/12/2025 19:10:00. 50 Economy ticket for £38 per person are available. Travel duration is 8h 30m
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FlixBus8h 55m010:40Frankfurt am Main AirportFrankfurt am Main Airport19:35PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 18/12/2025 10:40:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 18/12/2025 19:35:00. 50 Economy ticket for £38 per person are available. Travel duration is 8h 55m
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FlixBus8h 55m004:15Frankfurt am Main AirportFrankfurt am Main Airport13:10PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 18/12/2025 04:15:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 18/12/2025 13:10:00. 50 Economy ticket for £44 per person are available. Travel duration is 8h 55m
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FlixBus9h 55m001:15Frankfurt am Main AirportFrankfurt am Main Airport11:10PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 18/12/2025 01:15:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 18/12/2025 11:10:00. 50 Economy ticket for £45 per person are available. Travel duration is 9h 55m
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FlixBus10h 15m001:15Frankfurt am Main AirportFrankfurt am Main Airport11:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 18/12/2025 01:15:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 18/12/2025 11:30:00. 50 Economy ticket for £44 per person are available. Travel duration is 10h 15m
Fastest Flights Thursday
Fastest Buses Thursday
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Condor1h 0m009:20Frankfurt am Main AirportFrankfurt am Main Airport10:20Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 19/12/2025 09:20:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 19/12/2025 10:20:00. 50 Economy ticket for £104 per person are available. Travel duration is 1h 0m
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Condor1h 0m020:10Frankfurt am Main AirportFrankfurt am Main Airport21:10Prague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 19/12/2025 20:10:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 19/12/2025 21:10:00. 50 Economy ticket for £150 per person are available. Travel duration is 1h 0m
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Air Dolomiti1h 5m008:30Frankfurt am Main AirportFrankfurt am Main Airport09:35Prague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 19/12/2025 08:30:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 19/12/2025 09:35:00. 50 Economy ticket for £188 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m010:10Frankfurt am Main AirportFrankfurt am Main Airport11:15Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 19/12/2025 10:10:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 19/12/2025 11:15:00. 50 Economy ticket for £210 per person are available. Travel duration is 1h 5m
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Air Dolomiti1h 5m017:00Frankfurt am Main AirportFrankfurt am Main Airport18:05Prague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 19/12/2025 17:00:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 19/12/2025 18:05:00. 50 Economy ticket for £224 per person are available. Travel duration is 1h 5m
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FlixBus8h 35m000:20Frankfurt am Main AirportFrankfurt am Main Airport08:55PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 19/12/2025 00:20:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 19/12/2025 08:55:00. 50 Economy ticket for £61 per person are available. Travel duration is 8h 35m
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FlixBus9h 0m000:20Frankfurt am Main AirportFrankfurt am Main Airport09:20PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 19/12/2025 00:20:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 19/12/2025 09:20:00. 50 Economy ticket for £61 per person are available. Travel duration is 9h 0m
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FlixBus9h 0m001:05Frankfurt am Main AirportFrankfurt am Main Airport10:05PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 19/12/2025 01:05:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 19/12/2025 10:05:00. 50 Economy ticket for £66 per person are available. Travel duration is 9h 0m
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FlixBus9h 30m001:05Frankfurt am Main AirportFrankfurt am Main Airport10:35PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 19/12/2025 01:05:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 19/12/2025 10:35:00. 50 Economy ticket for £66 per person are available. Travel duration is 9h 30m
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FlixBus9h 55m001:15Frankfurt am Main AirportFrankfurt am Main Airport11:10PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 19/12/2025 01:15:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 19/12/2025 11:10:00. 50 Economy ticket for £61 per person are available. Travel duration is 9h 55m
Fastest Flights Friday
Fastest Buses Friday
Here you will find all operators and timetables for a
Bus from Mainz to Prague
What are the most popular stations in Mainz and Prague?
In Mainz, you will usually depart from Central Station, Central Bus Station or Laubenheim Train Station, while in Prague you will be arriving at Wilsonova Coach Station, ÚAN Florenc or Černý Most, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Prague from Mainz? With 8 connections between 1 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Mainz and Prague, you can pay as low as £23 with a Bus from RegioJet.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Condor: you will get to Prague in just 1h 0m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Mainz and Prague are FlixBus, Condor and Air Dolomiti, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Mainz and Prague is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Budenheim or to Horoměřice, and look at flights from Frankfurt am Main Airport, and landing at Prague Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Mainz to Prague?
The most popular companies between Mainz and Prague, are FlixBus, Condor and Air Dolomiti. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus and RegioJet
Airlines: Condor, Air Dolomiti and Lufthansa
All you need to know when you travel from Mainz to Prague
Check all information on comfort and services on all modes of transports from Mainz to Prague. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Mainz to Prague
How can I reach Prague from Mainz?
Every day, there are on average 8 connections between Bus and Flight, with which you can get to Prague from Mainz.
How far is Prague from Mainz?
The distance between Mainz and Prague is 442.1 km.
What is the most ecofriendly mode of transport between Mainz and Prague?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 12 kgs of CO2, a train 15 kgs, a car 75 kgs, and a flight 109 kgs.
What is the cheapest mode of transport from Mainz to Prague?
You can get to Prague with just £23 by taking a Bus from RegioJet.
What is the fastest way to get from Mainz to Prague?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Prague in just 1h 0m with a Flight from Condor.
More routes to Mainz and to Prague
Looking for more options? Here you can see the most popular routes to Mainz and to Prague. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Mainz
- Berlin to Mainz
- Brussels to Mainz
- Dresden to Mainz
- Frankfurt am Main Airport to Mainz
- Frankfurt Hahn Airport to Mainz
- Freiburg to Mainz
- Heidelberg to Mainz
- Kaiserslautern to Mainz
- Katowice to Mainz
- Koblenz to Mainz
- Munich to Mainz
- Paris to Mainz
- Saarbruecken to Mainz
- Simmern (Hunsrück) to Mainz
- Trips to Prague
- Amsterdam to Prague
- Berlin to Prague
- Bern to Prague
- Bratislava to Prague
- Brno to Prague
- Chemnitz to Prague
- Dresden to Prague
- Karlovy Vary to Prague
- Katowice to Prague
- Krakow to Prague
- Linz to Prague
- London to Prague
- Lyon to Prague
- Memmingen to Prague
- Milan to Prague
- Minsk to Prague
- Munich to Prague
- Nuremberg to Prague
- Paris to Prague
- Regensburg to Prague
- Teplice to Prague
- Třebíč to Prague
- Vienna to Prague
- Zurich to Prague

