What is the best way to travel from Comiso to Rome?
Looking for a trip? Check and compare all the available Flights and Buses to Rome from Comiso. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
What is the cheapest way to reach Rome from Comiso?
You can reach Rome with just £32 by taking a Flight from South African Express Airways, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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FlixBus16h 5m014:45ComisoVia Ghandi06:50RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Via Ghandi, Comiso (Italy) at 05/11/2026 14:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 06/11/2026 06:50:00. 50 Economy ticket for £62 per person are available. Travel duration is 16h 5m
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FlixBus21h 5m014:45ComisoVia Ghandi11:50RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Via Ghandi, Comiso (Italy) at 05/11/2026 14:45:00 to Anagnina Bus Station, Rome (Italy) arriving at 06/11/2026 11:50:00. 50 Economy ticket for £62 per person are available. Travel duration is 21h 5m
Cheapest Buses Thursday
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FlixBus21h 5m014:45ComisoVia Ghandi11:50RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Via Ghandi, Comiso (Italy) at 06/11/2026 14:45:00 to Anagnina Bus Station, Rome (Italy) arriving at 07/11/2026 11:50:00. 50 Economy ticket for £71 per person are available. Travel duration is 21h 5m
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FlixBus16h 5m014:45ComisoVia Ghandi06:50RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Via Ghandi, Comiso (Italy) at 06/11/2026 14:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 07/11/2026 06:50:00. 50 Economy ticket for £81 per person are available. Travel duration is 16h 5m
Cheapest Buses Friday
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South African Express Airways1h 15m018:45Comiso AirportComiso Airport20:00Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from South African Express Airways goes from Comiso Airport, Comiso Airport (Italy) at 07/11/2026 18:45:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 07/11/2026 20:00:00. 50 Economy ticket for £35 per person are available. Travel duration is 1h 15m
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South African Express Airways1h 15m007:10Comiso AirportComiso Airport08:25Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from South African Express Airways goes from Comiso Airport, Comiso Airport (Italy) at 07/11/2026 07:10:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 07/11/2026 08:25:00. 50 Economy ticket for £56 per person are available. Travel duration is 1h 15m
Cheapest Flights Saturday
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FlixBus21h 5m014:45ComisoVia Ghandi11:50RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Via Ghandi, Comiso (Italy) at 08/11/2026 14:45:00 to Anagnina Bus Station, Rome (Italy) arriving at 09/11/2026 11:50:00. 50 Economy ticket for £62 per person are available. Travel duration is 21h 5m
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FlixBus16h 5m014:45ComisoVia Ghandi06:50RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Via Ghandi, Comiso (Italy) at 08/11/2026 14:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 09/11/2026 06:50:00. 50 Economy ticket for £68 per person are available. Travel duration is 16h 5m
Cheapest Buses Sunday
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FlixBus16h 5m014:45ComisoVia Ghandi06:50RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Via Ghandi, Comiso (Italy) at 09/11/2026 14:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 10/11/2026 06:50:00. 50 Economy ticket for £46 per person are available. Travel duration is 16h 5m
Cheapest Buses Monday
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South African Express Airways1h 15m007:10Comiso AirportComiso Airport08:25Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from South African Express Airways goes from Comiso Airport, Comiso Airport (Italy) at 11/11/2026 07:10:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 11/11/2026 08:25:00. 50 Economy ticket for £32 per person are available. Travel duration is 1h 15m
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South African Express Airways1h 15m018:45Comiso AirportComiso Airport20:00Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from South African Express Airways goes from Comiso Airport, Comiso Airport (Italy) at 11/11/2026 18:45:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 11/11/2026 20:00:00. 50 Economy ticket for £32 per person are available. Travel duration is 1h 15m
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FlixBus21h 5m014:45ComisoVia Ghandi11:50RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Via Ghandi, Comiso (Italy) at 11/11/2026 14:45:00 to Anagnina Bus Station, Rome (Italy) arriving at 12/11/2026 11:50:00. 50 Economy ticket for £38 per person are available. Travel duration is 21h 5m
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FlixBus16h 5m014:45ComisoVia Ghandi06:50RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Via Ghandi, Comiso (Italy) at 11/11/2026 14:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 12/11/2026 06:50:00. 50 Economy ticket for £40 per person are available. Travel duration is 16h 5m
Cheapest Flights Wednesday
Cheapest Buses Wednesday
What are the fastest trips from Comiso to Rome?
You can get to Rome from Comiso in just 1h 15m with a Flight from South African Express Airways. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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FlixBus16h 5m014:45ComisoVia Ghandi06:50RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Via Ghandi, Comiso (Italy) at 05/11/2026 14:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 06/11/2026 06:50:00. 50 Economy ticket for £62 per person are available. Travel duration is 16h 5m
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FlixBus21h 5m014:45ComisoVia Ghandi11:50RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Via Ghandi, Comiso (Italy) at 05/11/2026 14:45:00 to Anagnina Bus Station, Rome (Italy) arriving at 06/11/2026 11:50:00. 50 Economy ticket for £62 per person are available. Travel duration is 21h 5m
Fastest Buses Thursday
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FlixBus16h 5m014:45ComisoVia Ghandi06:50RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Via Ghandi, Comiso (Italy) at 06/11/2026 14:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 07/11/2026 06:50:00. 50 Economy ticket for £81 per person are available. Travel duration is 16h 5m
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FlixBus21h 5m014:45ComisoVia Ghandi11:50RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Via Ghandi, Comiso (Italy) at 06/11/2026 14:45:00 to Anagnina Bus Station, Rome (Italy) arriving at 07/11/2026 11:50:00. 50 Economy ticket for £71 per person are available. Travel duration is 21h 5m
Fastest Buses Friday
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South African Express Airways1h 15m018:45Comiso AirportComiso Airport20:00Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from South African Express Airways goes from Comiso Airport, Comiso Airport (Italy) at 07/11/2026 18:45:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 07/11/2026 20:00:00. 50 Economy ticket for £35 per person are available. Travel duration is 1h 15m
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South African Express Airways1h 15m007:10Comiso AirportComiso Airport08:25Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from South African Express Airways goes from Comiso Airport, Comiso Airport (Italy) at 07/11/2026 07:10:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 07/11/2026 08:25:00. 50 Economy ticket for £56 per person are available. Travel duration is 1h 15m
Fastest Flights Saturday
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FlixBus16h 5m014:45ComisoVia Ghandi06:50RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Via Ghandi, Comiso (Italy) at 08/11/2026 14:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 09/11/2026 06:50:00. 50 Economy ticket for £68 per person are available. Travel duration is 16h 5m
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FlixBus21h 5m014:45ComisoVia Ghandi11:50RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Via Ghandi, Comiso (Italy) at 08/11/2026 14:45:00 to Anagnina Bus Station, Rome (Italy) arriving at 09/11/2026 11:50:00. 50 Economy ticket for £62 per person are available. Travel duration is 21h 5m
Fastest Buses Sunday
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FlixBus16h 5m014:45ComisoVia Ghandi06:50RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Via Ghandi, Comiso (Italy) at 09/11/2026 14:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 10/11/2026 06:50:00. 50 Economy ticket for £46 per person are available. Travel duration is 16h 5m
Fastest Buses Monday
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South African Express Airways1h 15m007:10Comiso AirportComiso Airport08:25Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from South African Express Airways goes from Comiso Airport, Comiso Airport (Italy) at 11/11/2026 07:10:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 11/11/2026 08:25:00. 50 Economy ticket for £32 per person are available. Travel duration is 1h 15m
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South African Express Airways1h 15m018:45Comiso AirportComiso Airport20:00Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from South African Express Airways goes from Comiso Airport, Comiso Airport (Italy) at 11/11/2026 18:45:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 11/11/2026 20:00:00. 50 Economy ticket for £32 per person are available. Travel duration is 1h 15m
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FlixBus16h 5m014:45ComisoVia Ghandi06:50RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Via Ghandi, Comiso (Italy) at 11/11/2026 14:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 12/11/2026 06:50:00. 50 Economy ticket for £40 per person are available. Travel duration is 16h 5m
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FlixBus21h 5m014:45ComisoVia Ghandi11:50RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Via Ghandi, Comiso (Italy) at 11/11/2026 14:45:00 to Anagnina Bus Station, Rome (Italy) arriving at 12/11/2026 11:50:00. 50 Economy ticket for £38 per person are available. Travel duration is 21h 5m
Fastest Flights Wednesday
Fastest Buses Wednesday
Here you will find all operators and timetables for a
Bus from Comiso to Rome
What are the most popular stations in Comiso and Rome?
In Comiso, you will usually depart from Bus Stop, Via Ghandi or Central Bus Station, while in Rome you will be arriving at Termini Bus Station, Tiburtina Train Station or Tiburtina Bus Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Rome from Comiso? With 2 connections between 1 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Comiso and Rome, you can pay as low as £32 with a Flight from South African Express Airways.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from South African Express Airways: you will get to Rome in just 1h 15m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Comiso and Rome are FlixBus and South African Express Airways, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Comiso and Rome is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Comiso Airport or to Settebagni, and look at flights from Comiso Airport, and landing at Rome Ciampino Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Comiso to Rome?
The most popular companies between Comiso and Rome, are FlixBus and South African Express Airways. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus
Airlines: South African Express Airways
All you need to know when you travel from Comiso to Rome
Check all information on comfort and services on all modes of transports from Comiso to Rome. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Comiso to Rome
How can I reach Rome from Comiso?
Every day, there are on average 2 connections between Flight and Bus, with which you can get to Rome from Comiso.
How far is Rome from Comiso?
The distance between Comiso and Rome is 579.7 km.
What is the most ecofriendly mode of transport between Comiso and Rome?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 16 kgs of CO2, a train 20 kgs, a car 99 kgs, and a flight 143 kgs.
What is the cheapest mode of transport from Comiso to Rome?
You can get to Rome with just £32 by taking a Flight from South African Express Airways.
What is the fastest way to get from Comiso to Rome?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Rome in just 1h 15m with a Flight from South African Express Airways.
More routes to Comiso and to Rome
Looking for more options? Here you can see the most popular routes to Comiso and to Rome. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Comiso
- Catania-Fontanarossa Airport to Comiso
- Trips to Rome
- Avellino to Rome
- Bari to Rome
- Battipaglia to Rome
- Caianello to Rome
- Catania to Rome
- Chieti to Rome
- Civitanova to Rome
- Cosenza to Rome
- Florence to Rome
- L'Aquila to Rome
- Lecce to Rome
- Milan to Rome
- Naples to Rome
- Perugia to Rome
- Pescara to Rome
- Porto D'Ascoli to Rome
- Potenza to Rome
- Rome Fiumicino Airport to Rome
- Sala Consilina to Rome
- Salerno to Rome
- Sibari to Rome
- Siracusa to Rome
- Teramo to Rome
- Vasto to Rome
