Which bus from Guatemala City to Santa Ana is the best?
Check the bus schedule for Guatemala City to Santa Ana. Here is a selection of the cheapest coach trips for the next days from bus operators like Cristobal Colon. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cristobal Colon | 5h 20m | 06:00 | Guatemala City | Monja Blanca | 11:20 | Santa Ana | Puma Santa Maria Gas Station | First Class | £17 |
A Bus from Cristobal Colon goes from Monja Blanca, Guatemala City (Guatemala) at 04/08/2026 06:00:00 to Puma Santa Maria Gas Station, Santa Ana (El Salvador) arriving at 04/08/2026 11:20:00. 50 First Class ticket for £17 per person are available. Travel duration is 5h 20m
|
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| Cristobal Colon | 5h 20m | 16:00 | Guatemala City | Monja Blanca | 21:20 | Santa Ana | Puma Santa Maria Gas Station | First Class | £17 |
A Bus from Cristobal Colon goes from Monja Blanca, Guatemala City (Guatemala) at 04/08/2026 16:00:00 to Puma Santa Maria Gas Station, Santa Ana (El Salvador) arriving at 04/08/2026 21:20:00. 50 First Class ticket for £17 per person are available. Travel duration is 5h 20m
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Best Price Offer: The price for the cheapest coach from Guatemala City to Santa Ana is £17 on 27/07/2026. Flexible travellers save on ticket prices.
All facts for Guatemala City to Santa Ana bus at a glance
Compare all coach operators like Cristobal Colon that travel daily 2 times by bus from Guatemala City to Santa Ana in one click. Book your Guatemala City to Santa Ana bus ticket starting from £17!
| Cheapest Bus | £17 |
| Fastest Bus | 5h 20m |
| Earliest Coach | 06:00 |
| Latest Coach | 16:00 |
| Daily Bus Connections | 2 Ø |
| Distance | 125.4 km |
| Coach Companies | Cristobal Colon |
What are the cheapest coach tickets from Guatemala City to Santa Ana?
Every day, 2 buses from 1 coach companies leave Guatemala City for Santa Ana. Check the table below to find the cheapest prices for coach tickets for this route, starting from 01/08/2026 and for the following days. Make sure get the cheapest bus ticket!
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday
27/07
Tuesday
28/07
Wednesday
29/07
Thursday
30/07
Friday
31/07
Saturday
01/08
£65
Sunday
02/08
£65
Monday
03/08
£65
Tuesday
04/08
£67
Wednesday
05/08
£65
Thursday
06/08
£65
Friday
07/08
Saturday
08/08
£65
Sunday
09/08
£65
Monday
10/08
£17
Tuesday
11/08
£17
Wednesday
12/08
£65
Thursday
13/08
Friday
14/08
£65
Saturday
15/08
£17
Sunday
16/08
Monday
17/08
£65
Tuesday
18/08
£65
Wednesday
19/08
£65
Thursday
20/08
£67
Friday
21/08
£17
Saturday
22/08
£65
Sunday
23/08
How to save money travelling from Guatemala City to Santa Ana
Travel can be expensive, but it doesn't need to be! Do you want to avoid paying higher prices for your trip? Plan your bus trips smartly. Here are a few hacks to save money on your coach journey.
Book the ticket from Guatemala City to Santa Ana in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Guatemala City to Santa Ana, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Guatemala City to Santa Ana are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
All bus stations and stops in Guatemala City and Santa Ana
Here is a map with all coach stations in Guatemala City and Santa Ana. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
All you need to know when you travel by bus from Guatemala City to Santa Ana
Check all information on comfort and services on the coaches from Guatemala City to Santa Ana. Which seat classes are available or what are the amenities of operators on your coach trip? Below you´ll find answers to your questions.
FAQs for Guatemala City to Santa Ana bus
How much does a Guatemala City Santa Ana coach trip cost?
This depends on, among other things, the day and travel time. The cheapest ticket for the Guatemala City Santa Ana bus trip is available from £17 and takes 5h 20m. Compare offers and save money!
How much could I save by comparing buses from Guatemala City to Santa Ana?
This connection is offered by 1 companies with ticket prices ranging from £17 to £17. Therefore, we suggest booking your ticket as soon as possible to ensure you’ll get the cheapest bus trip to Santa Ana.
How many connections are available for the Guatemala City Santa Ana route on average every day?
Each day, the bus route from Guatemala City to Santa Ana is offered by roughly 2 busses. By using our search, you can compare bus schedules and find your ideal trip.
How long does a bus to Santa Ana from Guatemala City take?
The quickest coach from Guatemala City to Santa Ana is provided by Cristobal Colon and takes 5h 20m. Coach tickets for this connection cost £17. However, keep in mind that the connection can take longer due to traffic.
What time is the first bus from Guatemala City to Santa Ana?
The earliest bus to Santa Ana departs from Guatemala City at 06:00. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.
What time is the last coach from Guatemala City to Santa Ana?
The latest bus to Santa Ana departs from Guatemala City at 16:00. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.
Which bus companies serve the Guatemala City Santa Ana route?
Passengers looking to travel from Guatemala City to Santa Ana can travel with Cristobal Colon. Compare all available bus tickets with our search to book the trip that works best for you.
Is there a direct bus between Guatemala City and Santa Ana?
You can check all the direct connections between Guatemala City and Santa Ana by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Cristobal Colon.
What can I take with me on the bus to Santa Ana from Guatemala City?
Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Guatemala City Santa Ana bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.
What equipment is available for the Guatemala City Santa Ana bus route?
The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Guatemala City to Santa Ana on your planned travel date.
How does CheckMyBus find the best coach deals from Guatemala City to Santa Ana?
CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Guatemala City and Santa Ana. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.
How does CheckMyBus technology work for trips from Guatemala City to Santa Ana?
Prices and availability for 2 trips between Guatemala City and Santa Ana change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.
Available seat classes which are offered on the bus route Guatemala City to Santa Ana
First Class
Best of the best: you will find the most comfortable accommodation to work or relax during your travel.
More bus routes to Guatemala City and to Santa Ana
Here’s an overview of the most popular bus routes to Guatemala City and to Santa Ana. Simply click on the connection of your choice, and you’ll find all the details about your bus route!
Popular Airport Transfers to Guatemala City and to Santa Ana
