Which bus from Guatemala City to Santa Ana is the best?
Check the bus schedule for Guatemala City to Santa Ana. Here is a selection of the cheapest coach trips for the next days from bus operators like Transporte del Sol. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Transporte del Sol | 3h 40m | 06:20 | Guatemala City | Shell Gas Station | 10:00 | Santa Ana | Puma Santa Maria Gas Station | Premium Economy | £26 |
A Bus from Transporte del Sol goes from Shell Gas Station, Guatemala City (Guatemala) at 05/12/2025 06:20:00 to Puma Santa Maria Gas Station, Santa Ana (El Salvador) arriving at 05/12/2025 10:00:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 3h 40m
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| Transporte del Sol | 3h 40m | 13:20 | Guatemala City | Shell Gas Station | 17:00 | Santa Ana | Puma Santa Maria Gas Station | Premium Economy | £26 |
A Bus from Transporte del Sol goes from Shell Gas Station, Guatemala City (Guatemala) at 05/12/2025 13:20:00 to Puma Santa Maria Gas Station, Santa Ana (El Salvador) arriving at 05/12/2025 17:00:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 3h 40m
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| Transporte del Sol | 4h 10m | 15:20 | Guatemala City | Shell Gas Station | 19:30 | Santa Ana | Puma Santa Maria Gas Station | Premium Economy | £26 |
A Bus from Transporte del Sol goes from Shell Gas Station, Guatemala City (Guatemala) at 05/12/2025 15:20:00 to Puma Santa Maria Gas Station, Santa Ana (El Salvador) arriving at 05/12/2025 19:30:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 4h 10m
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| Transporte del Sol | 5h 55m | 13:20 | Guatemala City | Shell Gas Station | 19:15 | Santa Ana | PUMA Energy Heróica Gas Station | Premium Economy | £52 |
A Bus from Transporte del Sol goes from Shell Gas Station, Guatemala City (Guatemala) at 05/12/2025 13:20:00 to PUMA Energy Heróica Gas Station, Santa Ana (El Salvador) arriving at 05/12/2025 19:15:00. 50 Premium Economy ticket for £52 per person are available. Travel duration is 5h 55m
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Best Price Offer: The price for the cheapest coach from Guatemala City to Santa Ana is £26 on 05/12/2025. Flexible travellers save on ticket prices.
All facts for Guatemala City to Santa Ana bus at a glance
Compare all coach operators like Transporte del Sol that travel daily 4 times by bus from Guatemala City to Santa Ana in one click. Book your Guatemala City to Santa Ana bus ticket starting from £26!
| Cheapest Bus | £26 |
| Fastest Bus | 3h 40m |
| Earliest Coach | 06:20 |
| Latest Coach | 15:20 |
| Daily Bus Connections | 4 Ø |
| Distance | 125.4 km |
| Coach Companies | Transporte del Sol |
What are the cheapest coach tickets from Guatemala City to Santa Ana?
Every day, 4 buses from 1 coach companies leave Guatemala City for Santa Ana. Check the table below to find the cheapest prices for coach tickets for this route, starting from 05/12/2025 and for the following days. Make sure get the cheapest bus ticket!
How to save money travelling from Guatemala City to Santa Ana
Book the ticket from Guatemala City to Santa Ana in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Guatemala City to Santa Ana, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Guatemala City to Santa Ana are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
What are the most popular bus companies from Guatemala City to Santa Ana?
Transporte del Sol from Guatemala City to Santa Ana
Here you will find the key facts about the Transporte del Sol bus route Guatemala City to Santa Ana:
| Cheapest Price | £26 |
| Fastest Coach | 3h 40m |
| Earliest Coach | 06:20 |
| Last Coach | 15:20 |
| Daily Connections | 4 Ø |
| Found on | 15/11/2025 |
All bus stations and stops in Guatemala City and Santa Ana
Here is a map with all coach stations in Guatemala City and Santa Ana. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
All you need to know when you travel by bus from Guatemala City to Santa Ana
FAQs for Guatemala City to Santa Ana bus
How much does a Guatemala City Santa Ana coach trip cost?
How much could I save by comparing buses from Guatemala City to Santa Ana?
How many connections are available for the Guatemala City Santa Ana route on average every day?
How long does a bus to Santa Ana from Guatemala City take?
What time is the first bus from Guatemala City to Santa Ana?
What time is the last coach from Guatemala City to Santa Ana?
Which bus companies serve the Guatemala City Santa Ana route?
Is there a direct bus between Guatemala City and Santa Ana?
What can I take with me on the bus to Santa Ana from Guatemala City?
What equipment is available for the Guatemala City Santa Ana bus route?
Available seat classes which are offered on the bus route Guatemala City to Santa Ana
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

