Which bus from Florence to Prague is the best?
Check the bus schedule for Florence to Prague. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus or RegioJet. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 15h 5m | 18:20 | Florence | Villa Costanza Bus Station | 09:25 | Prague | ÚAN Florenc | Economy | £52 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 18/09/2026 18:20:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 19/09/2026 09:25:00. 50 Economy ticket for £52 per person are available. Travel duration is 15h 5m
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| FlixBus | 17h 20m | 20:25 | Florence | Villa Costanza Bus Station | 13:45 | Prague | Wilsonova Coach Station | Economy | £64 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 18/09/2026 20:25:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 19/09/2026 13:45:00. 50 Economy ticket for £64 per person are available. Travel duration is 17h 20m
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| FlixBus | 17h 30m | 20:25 | Florence | Villa Costanza Bus Station | 13:55 | Prague | ÚAN Florenc | Economy | £64 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 18/09/2026 20:25:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 19/09/2026 13:55:00. 50 Economy ticket for £64 per person are available. Travel duration is 17h 30m
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| FlixBus | 20h 5m | 20:25 | Florence | Villa Costanza Bus Station | 16:30 | Prague | Roztyly | Economy | £78 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 18/09/2026 20:25:00 to Roztyly, Prague (Czech Republic) arriving at 19/09/2026 16:30:00. 50 Economy ticket for £78 per person are available. Travel duration is 20h 5m
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| FlixBus | 17h 10m | 18:20 | Florence | Villa Costanza Bus Station | 11:30 | Prague | Zličín | Economy | £80 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 18/09/2026 18:20:00 to Zličín, Prague (Czech Republic) arriving at 19/09/2026 11:30:00. 50 Economy ticket for £80 per person are available. Travel duration is 17h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 17h 20m | 20:25 | Florence | Villa Costanza Bus Station | 13:45 | Prague | Wilsonova Coach Station | Economy | £61 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 19/09/2026 20:25:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 20/09/2026 13:45:00. 50 Economy ticket for £61 per person are available. Travel duration is 17h 20m
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| FlixBus | 17h 30m | 20:25 | Florence | Villa Costanza Bus Station | 13:55 | Prague | ÚAN Florenc | Economy | £61 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 19/09/2026 20:25:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 20/09/2026 13:55:00. 50 Economy ticket for £61 per person are available. Travel duration is 17h 30m
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| FlixBus | 20h 5m | 20:25 | Florence | Villa Costanza Bus Station | 16:30 | Prague | Roztyly | Economy | £77 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 19/09/2026 20:25:00 to Roztyly, Prague (Czech Republic) arriving at 20/09/2026 16:30:00. 50 Economy ticket for £77 per person are available. Travel duration is 20h 5m
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| FlixBus | 17h 30m | 12:15 | Florence | Villa Costanza Bus Station | 05:45 | Prague | ÚAN Florenc | Economy | £78 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 19/09/2026 12:15:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 20/09/2026 05:45:00. 50 Economy ticket for £78 per person are available. Travel duration is 17h 30m
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| FlixBus | 18h 10m | 12:50 | Florence | Villa Costanza Bus Station | 07:00 | Prague | Wilsonova Coach Station | Economy | £81 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 19/09/2026 12:50:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 20/09/2026 07:00:00. 50 Economy ticket for £81 per person are available. Travel duration is 18h 10m
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FlixBus18h 55m010:50FlorenceVilla Costanza Bus Station15:30VeniceTronchetto Coach Station0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 21/09/2026 10:50:00 to Tronchetto Coach Station, Venice (Italy) arriving at 21/09/2026 15:30:00. 50 Economy ticket for £8 per person are available. Travel duration is 4h 40m
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FlixBus12h 25m017:20VeniceMestre Central Bus Station05:45PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Mestre Central Bus Station, Venice (Italy) at 21/09/2026 17:20:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 22/09/2026 05:45:00. 50 Economy ticket for £35 per person are available. Travel duration is 12h 25m
Waiting Time 1h 50m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 15h 5m | 18:20 | Florence | Villa Costanza Bus Station | 09:25 | Prague | ÚAN Florenc | Economy | £59 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 20/09/2026 18:20:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 21/09/2026 09:25:00. 50 Economy ticket for £59 per person are available. Travel duration is 15h 5m
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| FlixBus | 17h 20m | 20:25 | Florence | Villa Costanza Bus Station | 13:45 | Prague | Wilsonova Coach Station | Economy | £65 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 20/09/2026 20:25:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 21/09/2026 13:45:00. 50 Economy ticket for £65 per person are available. Travel duration is 17h 20m
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| FlixBus | 17h 30m | 20:25 | Florence | Villa Costanza Bus Station | 13:55 | Prague | ÚAN Florenc | Economy | £65 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 20/09/2026 20:25:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 21/09/2026 13:55:00. 50 Economy ticket for £65 per person are available. Travel duration is 17h 30m
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| FlixBus | 21h 30m | 05:20 | Florence | Villa Costanza Bus Station | 02:50 | Prague | Wilsonova Coach Station | Economy | £76 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 20/09/2026 05:20:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 21/09/2026 02:50:00. 50 Economy ticket for £76 per person are available. Travel duration is 21h 30m
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| FlixBus | 17h 0m | 00:30 | Florence | Piazzale Montelungo Coach Stop | 17:30 | Prague | Wilsonova Coach Station | Economy | £77 |
A Bus from FlixBus goes from Piazzale Montelungo Coach Stop, Florence (Italy) at 20/09/2026 00:30:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 20/09/2026 17:30:00. 50 Economy ticket for £77 per person are available. Travel duration is 17h 0m
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FlixBus18h 55m010:50FlorenceVilla Costanza Bus Station15:30VeniceTronchetto Coach Station0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 21/09/2026 10:50:00 to Tronchetto Coach Station, Venice (Italy) arriving at 21/09/2026 15:30:00. 50 Economy ticket for £8 per person are available. Travel duration is 4h 40m
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FlixBus12h 25m017:20VeniceMestre Central Bus Station05:45PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Mestre Central Bus Station, Venice (Italy) at 21/09/2026 17:20:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 22/09/2026 05:45:00. 50 Economy ticket for £35 per person are available. Travel duration is 12h 25m
Waiting Time 1h 50m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 15h 5m | 18:20 | Florence | Villa Costanza Bus Station | 09:25 | Prague | ÚAN Florenc | Economy | £44 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 21/09/2026 18:20:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 22/09/2026 09:25:00. 50 Economy ticket for £44 per person are available. Travel duration is 15h 5m
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| FlixBus | 17h 20m | 20:25 | Florence | Villa Costanza Bus Station | 13:45 | Prague | Wilsonova Coach Station | Economy | £47 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 21/09/2026 20:25:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 22/09/2026 13:45:00. 50 Economy ticket for £47 per person are available. Travel duration is 17h 20m
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| FlixBus | 17h 30m | 20:25 | Florence | Villa Costanza Bus Station | 13:55 | Prague | ÚAN Florenc | Economy | £47 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 21/09/2026 20:25:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 22/09/2026 13:55:00. 50 Economy ticket for £47 per person are available. Travel duration is 17h 30m
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| FlixBus | 18h 25m | 18:20 | Florence | Villa Costanza Bus Station | 12:45 | Prague | Na Knížecí Station | Economy | £54 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 21/09/2026 18:20:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 22/09/2026 12:45:00. 50 Economy ticket for £54 per person are available. Travel duration is 18h 25m
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| FlixBus | 20h 35m | 23:40 | Florence | Piazzale Montelungo Coach Stop | 20:15 | Prague | ÚAN Florenc | Economy | £55 |
A Bus from FlixBus goes from Piazzale Montelungo Coach Stop, Florence (Italy) at 21/09/2026 23:40:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 22/09/2026 20:15:00. 50 Economy ticket for £55 per person are available. Travel duration is 20h 35m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 17h 20m | 20:25 | Florence | Villa Costanza Bus Station | 13:45 | Prague | Wilsonova Coach Station | Economy | £44 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 22/09/2026 20:25:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 23/09/2026 13:45:00. 50 Economy ticket for £44 per person are available. Travel duration is 17h 20m
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| FlixBus | 15h 5m | 18:20 | Florence | Villa Costanza Bus Station | 09:25 | Prague | ÚAN Florenc | Economy | £44 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 22/09/2026 18:20:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 23/09/2026 09:25:00. 50 Economy ticket for £44 per person are available. Travel duration is 15h 5m
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| FlixBus | 17h 30m | 20:25 | Florence | Villa Costanza Bus Station | 13:55 | Prague | ÚAN Florenc | Economy | £44 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 22/09/2026 20:25:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 23/09/2026 13:55:00. 50 Economy ticket for £44 per person are available. Travel duration is 17h 30m
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| FlixBus | 20h 25m | 23:40 | Florence | Piazzale Montelungo Coach Stop | 20:05 | Prague | Wilsonova Coach Station | Economy | £52 |
A Bus from FlixBus goes from Piazzale Montelungo Coach Stop, Florence (Italy) at 22/09/2026 23:40:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 23/09/2026 20:05:00. 50 Economy ticket for £52 per person are available. Travel duration is 20h 25m
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| FlixBus | 20h 35m | 23:40 | Florence | Piazzale Montelungo Coach Stop | 20:15 | Prague | ÚAN Florenc | Economy | £52 |
A Bus from FlixBus goes from Piazzale Montelungo Coach Stop, Florence (Italy) at 22/09/2026 23:40:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 23/09/2026 20:15:00. 50 Economy ticket for £52 per person are available. Travel duration is 20h 35m
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Itabus16h 25m013:20FlorenceVilla Costanza Bus Station16:55VeniceMestre Central Bus Station0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 24/09/2026 13:20:00 to Mestre Central Bus Station, Venice (Italy) arriving at 24/09/2026 16:55:00. 50 Premium Economy ticket for £5 per person are available. Travel duration is 3h 35m
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FlixBus12h 25m017:20VeniceMestre Central Bus Station05:45PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Mestre Central Bus Station, Venice (Italy) at 24/09/2026 17:20:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 25/09/2026 05:45:00. 50 Economy ticket for £33 per person are available. Travel duration is 12h 25m
Waiting Time 0h 25m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 15h 5m | 18:20 | Florence | Villa Costanza Bus Station | 09:25 | Prague | ÚAN Florenc | Economy | £44 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 23/09/2026 18:20:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 24/09/2026 09:25:00. 50 Economy ticket for £44 per person are available. Travel duration is 15h 5m
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| FlixBus | 17h 20m | 20:25 | Florence | Villa Costanza Bus Station | 13:45 | Prague | Wilsonova Coach Station | Economy | £47 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 23/09/2026 20:25:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 24/09/2026 13:45:00. 50 Economy ticket for £47 per person are available. Travel duration is 17h 20m
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| FlixBus | 17h 30m | 20:25 | Florence | Villa Costanza Bus Station | 13:55 | Prague | ÚAN Florenc | Economy | £47 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 23/09/2026 20:25:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 24/09/2026 13:55:00. 50 Economy ticket for £47 per person are available. Travel duration is 17h 30m
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| RegioJet | 16h 25m | 16:45 | Florence | Villa Costanza Bus Station | 09:10 | Prague | ÚAN Florenc | Economy | £56 |
A Bus from RegioJet goes from Villa Costanza Bus Station, Florence (Italy) at 23/09/2026 16:45:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 24/09/2026 09:10:00. 50 Economy ticket for £56 per person are available. Travel duration is 16h 25m
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Itabus16h 25m013:20FlorenceVilla Costanza Bus Station16:55VeniceMestre Central Bus Station0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 24/09/2026 13:20:00 to Mestre Central Bus Station, Venice (Italy) arriving at 24/09/2026 16:55:00. 50 Premium Economy ticket for £5 per person are available. Travel duration is 3h 35m
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FlixBus12h 25m017:20VeniceMestre Central Bus Station05:45PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Mestre Central Bus Station, Venice (Italy) at 24/09/2026 17:20:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 25/09/2026 05:45:00. 50 Economy ticket for £33 per person are available. Travel duration is 12h 25m
Waiting Time 0h 25m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 17h 20m | 20:25 | Florence | Villa Costanza Bus Station | 13:45 | Prague | Wilsonova Coach Station | Economy | £52 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 24/09/2026 20:25:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 25/09/2026 13:45:00. 50 Economy ticket for £52 per person are available. Travel duration is 17h 20m
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| FlixBus | 17h 30m | 20:25 | Florence | Villa Costanza Bus Station | 13:55 | Prague | ÚAN Florenc | Economy | £52 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 24/09/2026 20:25:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 25/09/2026 13:55:00. 50 Economy ticket for £52 per person are available. Travel duration is 17h 30m
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| FlixBus | 20h 25m | 23:40 | Florence | Piazzale Montelungo Coach Stop | 20:05 | Prague | Wilsonova Coach Station | Economy | £57 |
A Bus from FlixBus goes from Piazzale Montelungo Coach Stop, Florence (Italy) at 24/09/2026 23:40:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 25/09/2026 20:05:00. 50 Economy ticket for £57 per person are available. Travel duration is 20h 25m
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| FlixBus | 20h 35m | 23:40 | Florence | Piazzale Montelungo Coach Stop | 20:15 | Prague | ÚAN Florenc | Economy | £57 |
A Bus from FlixBus goes from Piazzale Montelungo Coach Stop, Florence (Italy) at 24/09/2026 23:40:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 25/09/2026 20:15:00. 50 Economy ticket for £57 per person are available. Travel duration is 20h 35m
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| FlixBus | 19h 0m | 01:05 | Florence | Piazzale Montelungo Coach Stop | 20:05 | Prague | Wilsonova Coach Station | Economy | £59 |
A Bus from FlixBus goes from Piazzale Montelungo Coach Stop, Florence (Italy) at 24/09/2026 01:05:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 24/09/2026 20:05:00. 50 Economy ticket for £59 per person are available. Travel duration is 19h 0m
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Itabus16h 25m013:20FlorenceVilla Costanza Bus Station16:55VeniceMestre Central Bus Station0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 24/09/2026 13:20:00 to Mestre Central Bus Station, Venice (Italy) arriving at 24/09/2026 16:55:00. 50 Premium Economy ticket for £5 per person are available. Travel duration is 3h 35m
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FlixBus12h 25m017:20VeniceMestre Central Bus Station05:45PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Mestre Central Bus Station, Venice (Italy) at 24/09/2026 17:20:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 25/09/2026 05:45:00. 50 Economy ticket for £33 per person are available. Travel duration is 12h 25m
Waiting Time 0h 25m -
Best Price Offer: The price for the cheapest coach from Florence to Prague is £43 on 06/10/2026. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Florence and Prague?
All facts for Florence to Prague bus at a glance
Compare all coach operators like FlixBus and RegioJet that travel daily 38 times by bus from Florence to Prague in one click. Book your Florence to Prague bus ticket starting from £43!
| Cheapest Bus | £43 |
| Fastest Bus | 15h 5m |
| Earliest Coach | 00:30 |
| Latest Coach | 23:40 |
| Daily Bus Connections | 38 Ø |
| Distance | 741.5 km |
| Coach Companies | FlixBus and RegioJet |
What are the cheapest coach tickets from Florence to Prague?
Every day, 38 buses from 2 coach companies leave Florence for Prague. Check the table below to find the cheapest prices for coach tickets for this route, starting from 18/09/2026 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Florence to Prague
How to save money travelling from Florence to Prague
Book the ticket from Florence to Prague in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Florence to Prague, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Florence to Prague are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
All bus stations and stops in Florence and Prague
Here is a map with all coach stations in Florence and Prague. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
All you need to know when you travel by bus from Florence to Prague
FAQs for Florence to Prague bus
How much does a Florence Prague coach trip cost?
How much could I save by comparing buses from Florence to Prague?
How many connections are available for the Florence Prague route on average every day?
How long does a bus to Prague from Florence take?
What time is the first bus from Florence to Prague?
What time is the last coach from Florence to Prague?
Which bus companies serve the Florence Prague route?
Is there a direct bus between Florence and Prague?
What can I take with me on the bus to Prague from Florence?
What equipment is available for the Florence Prague bus route?
How does CheckMyBus find the best coach deals from Florence to Prague?
How does CheckMyBus technology work for trips from Florence to Prague?
Available seat classes which are offered on the bus route Florence to Prague
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Florence and to Prague
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