How to get from St. Louis, MO to Pittsburgh

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What is the best way to travel from St. Louis, MO to Pittsburgh?

Looking for a trip? Check and compare all the available Buses and Flights to Pittsburgh from St. Louis, MO. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
Bus is the cheapest, while Flight is the fastest way on this route
Transport type
Travel time
Cheapest price
Average price
Daily departures
Bus
13h 55m
£58
£71
8
Flight
3h 56m
£106
£256
17

What is the cheapest way to reach Pittsburgh from St. Louis, MO?

You can reach Pittsburgh with just £58 by taking a Bus from Greyhound US, but there are many more cheap offers: we have selected the best ones for you for the next few days here.

Sunday
from £111
Monday
from £58
Tuesday
from £264
Wednesday
from £62
Thursday
Friday
from £140
Saturday
from £106

    Cheapest Flights Sunday

  • Frontier Airlines
    23h 13m
    0
    17:47
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    18:00
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Frontier Airlines
    Economy
    from £111
  • United Airlines
    3h 56m
    0
    05:00
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    09:56
    Pittsburgh Airport
    Pittsburgh Airport
    0
    United Airlines
    Economy
    from £270
  • United Airlines
    5h 41m
    0
    06:33
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    13:14
    Pittsburgh Airport
    Pittsburgh Airport
    0
    United Airlines
    Economy
    from £270
  • Skyscanner
    6h 28m
    0
    06:00
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    13:28
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Skyscanner
    Economy
    from £324
  • Skyscanner
    4h 49m
    0
    08:15
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    14:04
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Skyscanner
    Economy
    from £324

    Cheapest Buses Monday

  • Greyhound US
    15h 10m
    0
    02:30
    St. Louis, MO
    Gateway Station
    17:40
    Pittsburgh
    Grant Street Transportation Center
    0
    Greyhound US
    Economy
    £58
  • Greyhound US
    15h 35m
    0
    08:45
    St. Louis, MO
    Gateway Station
    00:20
    Pittsburgh
    Grant Street Transportation Center
    0
    Greyhound US
    Economy
    £58
  • Greyhound US
    13h 55m
    0
    13:55
    St. Louis, MO
    Gateway Station
    03:50
    Pittsburgh
    Grant Street Transportation Center
    0
    Greyhound US
    Economy
    £58
  • FlixBus
    21h 5m
    0
    16:00
    St. Louis, MO
    Gateway Station
    13:05
    Pittsburgh
    Grant Street Transportation Center
    0
    FlixBus
    Economy
    £103

    Cheapest Flights Tuesday

  • United Airlines
    3h 56m
    0
    05:00
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    09:56
    Pittsburgh Airport
    Pittsburgh Airport
    0
    United Airlines
    Economy
    from £264
  • United Airlines
    5h 41m
    0
    06:33
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    13:14
    Pittsburgh Airport
    Pittsburgh Airport
    0
    United Airlines
    Economy
    from £264
  • Skyscanner
    4h 30m
    0
    10:00
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    15:30
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Skyscanner
    Economy
    from £264
  • Skyscanner
    6h 42m
    0
    06:00
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    13:42
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Skyscanner
    Economy
    from £271
  • Alaska Airlines
    11h 1m
    0
    06:41
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    18:42
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Alaska Airlines
    Economy
    from £417

    Cheapest Buses Wednesday

  • Greyhound US
    15h 10m
    0
    02:30
    St. Louis, MO
    Gateway Station
    17:40
    Pittsburgh
    Grant Street Transportation Center
    0
    Greyhound US
    Economy
    £62
  • Greyhound US
    15h 35m
    0
    08:45
    St. Louis, MO
    Gateway Station
    00:20
    Pittsburgh
    Grant Street Transportation Center
    0
    Greyhound US
    Economy
    £62
  • Greyhound US
    13h 55m
    0
    13:55
    St. Louis, MO
    Gateway Station
    03:50
    Pittsburgh
    Grant Street Transportation Center
    0
    Greyhound US
    Economy
    £62
  • FlixBus
    21h 5m
    0
    16:00
    St. Louis, MO
    Gateway Station
    13:05
    Pittsburgh
    Grant Street Transportation Center
    0
    FlixBus
    Economy
    £103
  • Cheapest Flights Wednesday

  • United Airlines
    3h 56m
    0
    05:00
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    09:56
    Pittsburgh Airport
    Pittsburgh Airport
    0
    United Airlines
    Economy
    from £263
  • United Airlines
    4h 14m
    0
    08:00
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    13:14
    Pittsburgh Airport
    Pittsburgh Airport
    0
    United Airlines
    Economy
    from £263
  • Skyscanner
    4h 30m
    0
    10:00
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    15:30
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Skyscanner
    Economy
    from £263
  • Skyscanner
    6h 42m
    0
    06:00
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    13:42
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Skyscanner
    Economy
    from £270
  • Alaska Airlines
    23h 2m
    0
    06:41
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    06:43
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Alaska Airlines
    Economy
    from £422

    Cheapest Flights Friday

  • Alaska Airlines
    14h 19m
    0
    15:24
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    06:43
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Alaska Airlines
    Economy
    from £140
  • Spirit Airlines
    7h 25m
    0
    14:55
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    23:20
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Spirit Airlines
    Economy
    from £148
  • United Airlines
    3h 56m
    0
    05:00
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    09:56
    Pittsburgh Airport
    Pittsburgh Airport
    0
    United Airlines
    Economy
    from £261
  • United Airlines
    5h 41m
    0
    06:33
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    13:14
    Pittsburgh Airport
    Pittsburgh Airport
    0
    United Airlines
    Economy
    from £261
  • Skyscanner
    4h 30m
    0
    10:00
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    15:30
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Skyscanner
    Economy
    from £261

    Cheapest Flights Saturday

  • Frontier Airlines
    14h 21m
    0
    17:40
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    09:01
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Frontier Airlines
    Economy
    from £106
  • Alaska Airlines
    14h 19m
    0
    15:24
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    06:43
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Alaska Airlines
    Economy
    from £174
  • United Airlines
    3h 56m
    0
    05:00
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    09:56
    Pittsburgh Airport
    Pittsburgh Airport
    0
    United Airlines
    Economy
    from £267
  • United Airlines
    5h 41m
    0
    06:33
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    13:14
    Pittsburgh Airport
    Pittsburgh Airport
    0
    United Airlines
    Economy
    from £267
  • Skyscanner
    4h 50m
    0
    08:15
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    14:05
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Skyscanner
    Economy
    from £267

What are the fastest trips from St. Louis, MO to Pittsburgh?

You can get to Pittsburgh from St. Louis, MO in just 3h 56m with a Flight from United Airlines. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.

Sunday
from 3h 56m
Monday
from 13h 55m
Tuesday
from 3h 56m
Wednesday
from 3h 56m
Thursday
Friday
from 3h 56m
Saturday
from 3h 56m

    Fastest Flights Sunday

  • United Airlines
    3h 56m
    0
    05:00
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    09:56
    Pittsburgh Airport
    Pittsburgh Airport
    0
    United Airlines
    Economy
    from £270
  • Skyscanner
    4h 49m
    0
    08:15
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    14:04
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Skyscanner
    Economy
    from £324
  • United Airlines
    5h 41m
    0
    06:33
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    13:14
    Pittsburgh Airport
    Pittsburgh Airport
    0
    United Airlines
    Economy
    from £270
  • Skyscanner
    6h 28m
    0
    06:00
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    13:28
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Skyscanner
    Economy
    from £324
  • Frontier Airlines
    23h 13m
    0
    17:47
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    18:00
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Frontier Airlines
    Economy
    from £111

    Fastest Buses Monday

  • Greyhound US
    13h 55m
    0
    13:55
    St. Louis, MO
    Gateway Station
    03:50
    Pittsburgh
    Grant Street Transportation Center
    0
    Greyhound US
    Economy
    £58
  • Greyhound US
    15h 10m
    0
    02:30
    St. Louis, MO
    Gateway Station
    17:40
    Pittsburgh
    Grant Street Transportation Center
    0
    Greyhound US
    Economy
    £58
  • Greyhound US
    15h 35m
    0
    08:45
    St. Louis, MO
    Gateway Station
    00:20
    Pittsburgh
    Grant Street Transportation Center
    0
    Greyhound US
    Economy
    £58
  • FlixBus
    21h 5m
    0
    16:00
    St. Louis, MO
    Gateway Station
    13:05
    Pittsburgh
    Grant Street Transportation Center
    0
    FlixBus
    Economy
    £103

    Fastest Flights Tuesday

  • United Airlines
    3h 56m
    0
    05:00
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    09:56
    Pittsburgh Airport
    Pittsburgh Airport
    0
    United Airlines
    Economy
    from £264
  • Skyscanner
    4h 30m
    0
    10:00
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    15:30
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Skyscanner
    Economy
    from £264
  • United Airlines
    5h 41m
    0
    06:33
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    13:14
    Pittsburgh Airport
    Pittsburgh Airport
    0
    United Airlines
    Economy
    from £264
  • Skyscanner
    6h 42m
    0
    06:00
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    13:42
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Skyscanner
    Economy
    from £271
  • Alaska Airlines
    11h 1m
    0
    06:41
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    18:42
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Alaska Airlines
    Economy
    from £417

    Fastest Flights Wednesday

  • United Airlines
    3h 56m
    0
    05:00
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    09:56
    Pittsburgh Airport
    Pittsburgh Airport
    0
    United Airlines
    Economy
    from £263
  • United Airlines
    4h 14m
    0
    08:00
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    13:14
    Pittsburgh Airport
    Pittsburgh Airport
    0
    United Airlines
    Economy
    from £263
  • Skyscanner
    4h 30m
    0
    10:00
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    15:30
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Skyscanner
    Economy
    from £263
  • Skyscanner
    6h 42m
    0
    06:00
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    13:42
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Skyscanner
    Economy
    from £270
  • Alaska Airlines
    23h 2m
    0
    06:41
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    06:43
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Alaska Airlines
    Economy
    from £422
  • Fastest Buses Wednesday

  • Greyhound US
    13h 55m
    0
    13:55
    St. Louis, MO
    Gateway Station
    03:50
    Pittsburgh
    Grant Street Transportation Center
    0
    Greyhound US
    Economy
    £62
  • Greyhound US
    15h 10m
    0
    02:30
    St. Louis, MO
    Gateway Station
    17:40
    Pittsburgh
    Grant Street Transportation Center
    0
    Greyhound US
    Economy
    £62
  • Greyhound US
    15h 35m
    0
    08:45
    St. Louis, MO
    Gateway Station
    00:20
    Pittsburgh
    Grant Street Transportation Center
    0
    Greyhound US
    Economy
    £62
  • FlixBus
    21h 5m
    0
    16:00
    St. Louis, MO
    Gateway Station
    13:05
    Pittsburgh
    Grant Street Transportation Center
    0
    FlixBus
    Economy
    £103

    Fastest Flights Friday

  • United Airlines
    3h 56m
    0
    05:00
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    09:56
    Pittsburgh Airport
    Pittsburgh Airport
    0
    United Airlines
    Economy
    from £261
  • Skyscanner
    4h 30m
    0
    10:00
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    15:30
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Skyscanner
    Economy
    from £261
  • United Airlines
    5h 41m
    0
    06:33
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    13:14
    Pittsburgh Airport
    Pittsburgh Airport
    0
    United Airlines
    Economy
    from £261
  • Spirit Airlines
    7h 25m
    0
    14:55
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    23:20
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Spirit Airlines
    Economy
    from £148
  • Alaska Airlines
    14h 19m
    0
    15:24
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    06:43
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Alaska Airlines
    Economy
    from £140

    Fastest Flights Saturday

  • United Airlines
    3h 56m
    0
    05:00
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    09:56
    Pittsburgh Airport
    Pittsburgh Airport
    0
    United Airlines
    Economy
    from £267
  • Skyscanner
    4h 50m
    0
    08:15
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    14:05
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Skyscanner
    Economy
    from £267
  • United Airlines
    5h 41m
    0
    06:33
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    13:14
    Pittsburgh Airport
    Pittsburgh Airport
    0
    United Airlines
    Economy
    from £267
  • Alaska Airlines
    14h 19m
    0
    15:24
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    06:43
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Alaska Airlines
    Economy
    from £174
  • Frontier Airlines
    14h 21m
    0
    17:40
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    09:01
    Pittsburgh Airport
    Pittsburgh Airport
    0
    Frontier Airlines
    Economy
    from £106
Here you will find all operators and timetables for a Bus from St. Louis, MO to Pittsburgh

What are the most popular stations in St. Louis, MO and Pittsburgh?

In St. Louis, MO, you will usually depart from Gateway Station, Lindbergh @ Hackberry NB Bus Stop or Skinker Boulevard, while in Pittsburgh you will be arriving at David L. Lawrence Convention Center, Central Station or University of, but there are many more stops to explore in both locations.

How do I decide? Some tips and tricks from our experience

Are you having trouble deciding on how to get to Pittsburgh from St. Louis, MO? With 5 connections between 2 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.

Look for the lowest price

Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between St. Louis, MO and Pittsburgh, you can pay as low as £58 with a Bus from Greyhound US.

Travel duration

Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from United Airlines: you will get to Pittsburgh in just 3h 56m.

Comfort makes all the difference

You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting St. Louis, MO and Pittsburgh are United Airlines, Skyscanner and Greyhound US, but be sure to check what they have to offer!

Save money with deals, and always compare

One last tip? Even if you live in St. Louis, MO and Pittsburgh is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Sauget, IL or to Green Tree, PA, and look at flights from St. Louis Lambert Airport, and landing at Pittsburgh Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!

Which companies offer a trip from St. Louis, MO to Pittsburgh?

The most popular companies between St. Louis, MO and Pittsburgh, are United Airlines, Skyscanner and Greyhound US. Be sure to check their seat class offers and the amenities that they provide.

Bus companies: Greyhound US and FlixBus

Airlines: United Airlines, Skyscanner, Alaska Airlines and 2 more.

All you need to know when you travel from St. Louis, MO to Pittsburgh

Check all information on comfort and services on all modes of transports from St. Louis, MO to Pittsburgh. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.

FAQs about the trip from St. Louis, MO to Pittsburgh

How can I reach Pittsburgh from St. Louis, MO?

Every day, there are on average 5 connections between Bus and Flight, with which you can get to Pittsburgh from St. Louis, MO.

How far is Pittsburgh from St. Louis, MO?

The distance between St. Louis, MO and Pittsburgh is 898.0 km.

What is the most ecofriendly mode of transport between St. Louis, MO and Pittsburgh?

Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance. On this particular route, a bus will emit, per person, a total of 24 kgs of CO2, a train 31 kgs, a car 153 kgs, and a flight 221 kgs.

What is the cheapest mode of transport from St. Louis, MO to Pittsburgh?

You can get to Pittsburgh with just £58 by taking a Bus from Greyhound US.

What is the fastest way to get from St. Louis, MO to Pittsburgh?

While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Pittsburgh in just 3h 56m with a Flight from United Airlines.

More routes to St. Louis, MO and to Pittsburgh

Looking for more options? Here you can see the most popular routes to St. Louis, MO and to Pittsburgh. Simply click on a connection, and you’ll find all the details about the route!

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