How to get from San Diego to Mesa, AZ

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What is the best way to travel from San Diego to Mesa, AZ?

Looking for a trip? Check and compare all the available Buses and Flights to Mesa, AZ from San Diego. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
Bus is the cheapest, while Flight is the fastest way on this route
Transport type
Travel time
Cheapest price
Average price
Daily departures
Bus
8h 10m
£31
£41
20
Flight
1h 25m
£41
£114
7

What is the cheapest way to reach Mesa, AZ from San Diego?

You can reach Mesa, AZ with just £31 by taking a Bus from FlixBus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.

Thursday
from £87
Friday
from £54
Saturday
from £43
Sunday
from £76
Monday
from £31
Tuesday
from £43
Wednesday
from £35

    Cheapest Flights Thursday

  • Frontier Airlines
    1h 31m
    0
    13:10
    San Diego Airport
    San Diego Airport
    14:41
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    Frontier Airlines
    Economy
    from £87
  • Frontier Airlines
    1h 26m
    0
    15:18
    San Diego Airport
    San Diego Airport
    16:44
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    Frontier Airlines
    Economy
    from £87
  • American Airlines
    1h 37m
    0
    06:25
    San Diego Airport
    San Diego Airport
    08:02
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    American Airlines
    Economy
    from £205
  • American Airlines
    1h 28m
    0
    09:50
    San Diego Airport
    San Diego Airport
    11:18
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    American Airlines
    Economy
    from £205
  • American Airlines
    1h 26m
    0
    12:48
    San Diego Airport
    San Diego Airport
    14:14
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    American Airlines
    Economy
    from £205

    Cheapest Buses Friday

  • FlixBus
    10h 35m
    0
    07:35
    San Diego
    Old Town Transit Center
    18:10
    Mesa, AZ
    Greyhound
    0
    FlixBus
    Economy
    £54
  • FlixBus
    13h 5m
    0
    18:35
    San Diego
    Old Town Transit Center
    07:40
    Mesa, AZ
    Greyhound
    0
    FlixBus
    Economy
    £54
  • FlixBus
    12h 40m
    0
    19:00
    San Diego
    La Jolla Village
    07:40
    Mesa, AZ
    Greyhound
    0
    FlixBus
    Economy
    £54
  • Greyhound US
    8h 10m
    0
    10:00
    San Diego
    Old Town Transit Center
    18:10
    Mesa, AZ
    Greyhound
    0
    Greyhound US
    Economy
    £55
  • Greyhound US
    12h 5m
    0
    19:35
    San Diego
    Old Town Transit Center
    07:40
    Mesa, AZ
    Greyhound
    0
    Greyhound US
    Economy
    £55

    Cheapest Flights Saturday

  • Frontier Airlines
    1h 31m
    0
    13:10
    San Diego Airport
    San Diego Airport
    14:41
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    Frontier Airlines
    Economy
    from £43
  • American Airlines
    1h 37m
    0
    06:25
    San Diego Airport
    San Diego Airport
    08:02
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    American Airlines
    Economy
    from £160
  • American Airlines
    1h 28m
    0
    09:50
    San Diego Airport
    San Diego Airport
    11:18
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    American Airlines
    Economy
    from £160
  • American Airlines
    1h 26m
    0
    12:48
    San Diego Airport
    San Diego Airport
    14:14
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    American Airlines
    Economy
    from £160

    Cheapest Flights Sunday

  • Frontier Airlines
    1h 30m
    0
    21:30
    San Diego Airport
    San Diego Airport
    23:00
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    Frontier Airlines
    Economy
    from £76
  • Frontier Airlines
    1h 31m
    0
    13:10
    San Diego Airport
    San Diego Airport
    14:41
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    Frontier Airlines
    Economy
    from £126
  • American Airlines
    1h 37m
    0
    06:25
    San Diego Airport
    San Diego Airport
    08:02
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    American Airlines
    Economy
    from £160
  • American Airlines
    1h 28m
    0
    09:50
    San Diego Airport
    San Diego Airport
    11:18
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    American Airlines
    Economy
    from £160
  • American Airlines
    1h 26m
    0
    12:48
    San Diego Airport
    San Diego Airport
    14:14
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    American Airlines
    Economy
    from £160

    Cheapest Buses Monday

  • FlixBus
    13h 45m
    0
    13:00
    San Diego
    Old Town Transit Center
    02:45
    Mesa, AZ
    Greyhound
    0
    FlixBus
    Economy
    £31
  • FlixBus
    14h 45m
    0
    12:00
    San Diego
    Seaport Village
    02:45
    Mesa, AZ
    Greyhound
    0
    FlixBus
    Economy
    £31
  • FlixBus
    14h 25m
    0
    12:20
    San Diego
    Balboa Park
    02:45
    Mesa, AZ
    Greyhound
    0
    FlixBus
    Economy
    £31
  • Greyhound US
    12h 45m
    0
    14:00
    San Diego
    Old Town Transit Center
    02:45
    Mesa, AZ
    Greyhound
    0
    Greyhound US
    Economy
    £31
  • Greyhound US
    8h 10m
    0
    10:00
    San Diego
    Old Town Transit Center
    18:10
    Mesa, AZ
    Greyhound
    0
    Greyhound US
    Economy
    £34
  • Cheapest Flights Monday

  • Frontier Airlines
    1h 31m
    0
    13:10
    San Diego Airport
    San Diego Airport
    14:41
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    Frontier Airlines
    Economy
    from £41
  • Frontier Airlines
    1h 30m
    0
    21:30
    San Diego Airport
    San Diego Airport
    23:00
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    Frontier Airlines
    Economy
    from £41
  • American Airlines
    1h 37m
    0
    06:25
    San Diego Airport
    San Diego Airport
    08:02
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    American Airlines
    Economy
    from £87
  • American Airlines
    1h 26m
    0
    12:48
    San Diego Airport
    San Diego Airport
    14:14
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    American Airlines
    Economy
    from £87
  • American Airlines
    1h 25m
    0
    19:33
    San Diego Airport
    San Diego Airport
    20:58
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    American Airlines
    Economy
    from £87

    Cheapest Flights Tuesday

  • Frontier Airlines
    1h 26m
    0
    15:18
    San Diego Airport
    San Diego Airport
    16:44
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    Frontier Airlines
    Economy
    from £43
  • American Airlines
    1h 37m
    0
    06:25
    San Diego Airport
    San Diego Airport
    08:02
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    American Airlines
    Economy
    from £77
  • American Airlines
    1h 28m
    0
    09:50
    San Diego Airport
    San Diego Airport
    11:18
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    American Airlines
    Economy
    from £77
  • American Airlines
    1h 25m
    0
    19:33
    San Diego Airport
    San Diego Airport
    20:58
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    American Airlines
    Economy
    from £77

    Cheapest Buses Wednesday

  • FlixBus
    14h 35m
    0
    12:10
    San Diego
    Old Town Transit Center
    02:45
    Mesa, AZ
    Greyhound
    0
    FlixBus
    Economy
    £35
  • FlixBus
    14h 5m
    0
    12:40
    San Diego
    La Jolla Village
    02:45
    Mesa, AZ
    Greyhound
    0
    FlixBus
    Economy
    £35
  • FlixBus
    14h 55m
    0
    11:50
    San Diego
    Seaport Village
    02:45
    Mesa, AZ
    Greyhound
    0
    FlixBus
    Economy
    £35
  • Greyhound US
    12h 45m
    0
    14:00
    San Diego
    Old Town Transit Center
    02:45
    Mesa, AZ
    Greyhound
    0
    Greyhound US
    Economy
    £35
  • Greyhound US
    12h 5m
    0
    19:35
    San Diego
    Old Town Transit Center
    07:40
    Mesa, AZ
    Greyhound
    0
    Greyhound US
    Economy
    £41

What are the fastest trips from San Diego to Mesa, AZ?

You can get to Mesa, AZ from San Diego in just 1h 25m with a Flight from American Airlines. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.

Thursday
from 1h 26m
Friday
from 8h 10m
Saturday
from 1h 26m
Sunday
from 1h 26m
Monday
from 1h 25m
Tuesday
from 1h 25m
Wednesday
from 12h 5m

    Fastest Flights Thursday

  • Frontier Airlines
    1h 26m
    0
    15:18
    San Diego Airport
    San Diego Airport
    16:44
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    Frontier Airlines
    Economy
    from £87
  • American Airlines
    1h 26m
    0
    12:48
    San Diego Airport
    San Diego Airport
    14:14
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    American Airlines
    Economy
    from £205
  • American Airlines
    1h 28m
    0
    09:50
    San Diego Airport
    San Diego Airport
    11:18
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    American Airlines
    Economy
    from £205
  • Frontier Airlines
    1h 31m
    0
    13:10
    San Diego Airport
    San Diego Airport
    14:41
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    Frontier Airlines
    Economy
    from £87
  • American Airlines
    1h 37m
    0
    06:25
    San Diego Airport
    San Diego Airport
    08:02
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    American Airlines
    Economy
    from £205

    Fastest Buses Friday

  • Greyhound US
    8h 10m
    0
    10:00
    San Diego
    Old Town Transit Center
    18:10
    Mesa, AZ
    Greyhound
    0
    Greyhound US
    Economy
    £55
  • FlixBus
    10h 35m
    0
    07:35
    San Diego
    Old Town Transit Center
    18:10
    Mesa, AZ
    Greyhound
    0
    FlixBus
    Economy
    £54
  • Greyhound US
    12h 5m
    0
    19:35
    San Diego
    Old Town Transit Center
    07:40
    Mesa, AZ
    Greyhound
    0
    Greyhound US
    Economy
    £55
  • FlixBus
    12h 40m
    0
    19:00
    San Diego
    La Jolla Village
    07:40
    Mesa, AZ
    Greyhound
    0
    FlixBus
    Economy
    £54
  • FlixBus
    13h 5m
    0
    18:35
    San Diego
    Old Town Transit Center
    07:40
    Mesa, AZ
    Greyhound
    0
    FlixBus
    Economy
    £54

    Fastest Flights Saturday

  • American Airlines
    1h 26m
    0
    12:48
    San Diego Airport
    San Diego Airport
    14:14
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    American Airlines
    Economy
    from £160
  • American Airlines
    1h 28m
    0
    09:50
    San Diego Airport
    San Diego Airport
    11:18
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    American Airlines
    Economy
    from £160
  • Frontier Airlines
    1h 31m
    0
    13:10
    San Diego Airport
    San Diego Airport
    14:41
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    Frontier Airlines
    Economy
    from £43
  • American Airlines
    1h 37m
    0
    06:25
    San Diego Airport
    San Diego Airport
    08:02
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    American Airlines
    Economy
    from £160

    Fastest Flights Sunday

  • American Airlines
    1h 26m
    0
    12:48
    San Diego Airport
    San Diego Airport
    14:14
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    American Airlines
    Economy
    from £160
  • American Airlines
    1h 28m
    0
    09:50
    San Diego Airport
    San Diego Airport
    11:18
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    American Airlines
    Economy
    from £160
  • Frontier Airlines
    1h 30m
    0
    21:30
    San Diego Airport
    San Diego Airport
    23:00
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    Frontier Airlines
    Economy
    from £76
  • Frontier Airlines
    1h 31m
    0
    13:10
    San Diego Airport
    San Diego Airport
    14:41
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    Frontier Airlines
    Economy
    from £126
  • American Airlines
    1h 37m
    0
    06:25
    San Diego Airport
    San Diego Airport
    08:02
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    American Airlines
    Economy
    from £160

    Fastest Flights Monday

  • American Airlines
    1h 25m
    0
    19:33
    San Diego Airport
    San Diego Airport
    20:58
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    American Airlines
    Economy
    from £87
  • American Airlines
    1h 26m
    0
    12:48
    San Diego Airport
    San Diego Airport
    14:14
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    American Airlines
    Economy
    from £87
  • Frontier Airlines
    1h 30m
    0
    21:30
    San Diego Airport
    San Diego Airport
    23:00
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    Frontier Airlines
    Economy
    from £41
  • Frontier Airlines
    1h 31m
    0
    13:10
    San Diego Airport
    San Diego Airport
    14:41
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    Frontier Airlines
    Economy
    from £41
  • American Airlines
    1h 37m
    0
    06:25
    San Diego Airport
    San Diego Airport
    08:02
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    American Airlines
    Economy
    from £87
  • Fastest Buses Monday

  • Greyhound US
    8h 10m
    0
    10:00
    San Diego
    Old Town Transit Center
    18:10
    Mesa, AZ
    Greyhound
    0
    Greyhound US
    Economy
    £34
  • Greyhound US
    12h 45m
    0
    14:00
    San Diego
    Old Town Transit Center
    02:45
    Mesa, AZ
    Greyhound
    0
    Greyhound US
    Economy
    £31
  • FlixBus
    13h 45m
    0
    13:00
    San Diego
    Old Town Transit Center
    02:45
    Mesa, AZ
    Greyhound
    0
    FlixBus
    Economy
    £31
  • FlixBus
    14h 25m
    0
    12:20
    San Diego
    Balboa Park
    02:45
    Mesa, AZ
    Greyhound
    0
    FlixBus
    Economy
    £31
  • FlixBus
    14h 45m
    0
    12:00
    San Diego
    Seaport Village
    02:45
    Mesa, AZ
    Greyhound
    0
    FlixBus
    Economy
    £31

    Fastest Flights Tuesday

  • American Airlines
    1h 25m
    0
    19:33
    San Diego Airport
    San Diego Airport
    20:58
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    American Airlines
    Economy
    from £77
  • Frontier Airlines
    1h 26m
    0
    15:18
    San Diego Airport
    San Diego Airport
    16:44
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    Frontier Airlines
    Economy
    from £43
  • American Airlines
    1h 28m
    0
    09:50
    San Diego Airport
    San Diego Airport
    11:18
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    American Airlines
    Economy
    from £77
  • American Airlines
    1h 37m
    0
    06:25
    San Diego Airport
    San Diego Airport
    08:02
    Phoenix Sky Harbor Airport
    Phoenix Sky Harbor Airport
    0
    American Airlines
    Economy
    from £77

    Fastest Buses Wednesday

  • Greyhound US
    12h 5m
    0
    19:35
    San Diego
    Old Town Transit Center
    07:40
    Mesa, AZ
    Greyhound
    0
    Greyhound US
    Economy
    £41
  • Greyhound US
    12h 45m
    0
    14:00
    San Diego
    Old Town Transit Center
    02:45
    Mesa, AZ
    Greyhound
    0
    Greyhound US
    Economy
    £35
  • FlixBus
    14h 5m
    0
    12:40
    San Diego
    La Jolla Village
    02:45
    Mesa, AZ
    Greyhound
    0
    FlixBus
    Economy
    £35
  • FlixBus
    14h 35m
    0
    12:10
    San Diego
    Old Town Transit Center
    02:45
    Mesa, AZ
    Greyhound
    0
    FlixBus
    Economy
    £35
  • FlixBus
    14h 55m
    0
    11:50
    San Diego
    Seaport Village
    02:45
    Mesa, AZ
    Greyhound
    0
    FlixBus
    Economy
    £35
Here you will find all operators and timetables for a Bus from San Diego to Mesa, AZ

What are the most popular stations in San Diego and Mesa, AZ?

In San Diego, you will usually depart from Santa Fe Depot, San Ysidro Transit Center or Old Town Transit Center, while in Mesa, AZ you will be arriving at Greyhound or Fry’s Fuel Center, but there are many more stops to explore in both locations.

How do I decide? Some tips and tricks from our experience

Are you having trouble deciding on how to get to Mesa, AZ from San Diego? With 5 connections between 2 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.

Look for the lowest price

Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between San Diego and Mesa, AZ, you can pay as low as £31 with a Bus from FlixBus.

Travel duration

Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from American Airlines: you will get to Mesa, AZ in just 1h 25m.

Comfort makes all the difference

You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting San Diego and Mesa, AZ are American Airlines, FlixBus and Frontier Airlines, but be sure to check what they have to offer!

Save money with deals, and always compare

One last tip? Even if you live in San Diego and Mesa, AZ is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from San Diego Airport or to Tempe, AZ, and look at flights from Tijuana Airport, and landing at Phoenix Sky Harbor Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!

Which companies offer a trip from San Diego to Mesa, AZ?

The most popular companies between San Diego and Mesa, AZ, are American Airlines, FlixBus and Frontier Airlines. Be sure to check their seat class offers and the amenities that they provide.

Bus companies: FlixBus and Greyhound US

Airlines: American Airlines and Frontier Airlines

All you need to know when you travel from San Diego to Mesa, AZ

Check all information on comfort and services on all modes of transports from San Diego to Mesa, AZ. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.

FAQs about the trip from San Diego to Mesa, AZ

How can I reach Mesa, AZ from San Diego?

Every day, there are on average 5 connections between Bus and Flight, with which you can get to Mesa, AZ from San Diego.

How far is Mesa, AZ from San Diego?

The distance between San Diego and Mesa, AZ is 501.6 km.

What is the most ecofriendly mode of transport between San Diego and Mesa, AZ?

Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance. On this particular route, a bus will emit, per person, a total of 14 kgs of CO2, a train 18 kgs, a car 85 kgs, and a flight 123 kgs.

What is the cheapest mode of transport from San Diego to Mesa, AZ?

You can get to Mesa, AZ with just £31 by taking a Bus from FlixBus.

What is the fastest way to get from San Diego to Mesa, AZ?

While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Mesa, AZ in just 1h 25m with a Flight from American Airlines.

More routes to San Diego and to Mesa, AZ

Looking for more options? Here you can see the most popular routes to San Diego and to Mesa, AZ. Simply click on a connection, and you’ll find all the details about the route!

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