What is the best way to travel from San Antonio, TX to San Diego?
Looking for a trip? Check and compare all the available Buses to San Diego from San Antonio, TX. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 3 available companies to find your perfect trip!
What is the cheapest way to reach San Diego from San Antonio, TX?
You can reach San Diego with just £124 by taking a Bus from Greyhound Lines Mexico, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Greyhound Lines Mexico48h 55m019:15San Antonio, TXCoach Station18:10San DiegoOld Town Transit Center0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 15/12/2025 19:15:00 to Old Town Transit Center, San Diego (USA) arriving at 17/12/2025 18:10:00. 50 Economy ticket for £124 per person are available. Travel duration is 48h 55m
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Greyhound Lines Mexico53h 0m019:15San Antonio, TXCoach Station22:15San DiegoSeaport Village0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 15/12/2025 19:15:00 to Seaport Village, San Diego (USA) arriving at 17/12/2025 22:15:00. 50 Economy ticket for £124 per person are available. Travel duration is 53h 0m
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Greyhound US37h 0m006:10San Antonio, TXCoach Station17:10San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 15/12/2025 06:10:00 to San Ysidro Transit Center, San Diego (USA) arriving at 16/12/2025 17:10:00. 50 Economy ticket for £148 per person are available. Travel duration is 37h 0m
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Greyhound US42h 5m006:10San Antonio, TXCoach Station22:15San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 15/12/2025 06:10:00 to Seaport Village, San Diego (USA) arriving at 16/12/2025 22:15:00. 50 Economy ticket for £148 per person are available. Travel duration is 42h 5m
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FlixBus43h 35m018:10San Antonio, TXCoach Station11:45San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 15/12/2025 18:10:00 to Old Town Transit Center, San Diego (USA) arriving at 17/12/2025 11:45:00. 50 Economy ticket for £148 per person are available. Travel duration is 43h 35m
Cheapest Buses Monday
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Greyhound Lines Mexico43h 15m001:30San Antonio, TXCoach Station18:45San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 16/12/2025 01:30:00 to San Ysidro Transit Center, San Diego (USA) arriving at 17/12/2025 18:45:00. 50 Economy ticket for £159 per person are available. Travel duration is 43h 15m
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FlixBus44h 10m018:10San Antonio, TXCoach Station12:20San DiegoSan Ysidro Transit Center0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 16/12/2025 18:10:00 to San Ysidro Transit Center, San Diego (USA) arriving at 18/12/2025 12:20:00. 50 Economy ticket for £164 per person are available. Travel duration is 44h 10m
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Greyhound Lines Mexico42h 40m006:05San Antonio, TXCoach Station22:45San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 16/12/2025 06:05:00 to San Ysidro Transit Center, San Diego (USA) arriving at 17/12/2025 22:45:00. 50 Economy ticket for £172 per person are available. Travel duration is 42h 40m
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Greyhound Lines Mexico49h 30m019:15San Antonio, TXCoach Station18:45San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 16/12/2025 19:15:00 to San Ysidro Transit Center, San Diego (USA) arriving at 18/12/2025 18:45:00. 50 Economy ticket for £186 per person are available. Travel duration is 49h 30m
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FlixBus46h 0m018:10San Antonio, TXCoach Station14:10San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 16/12/2025 18:10:00 to Old Town Transit Center, San Diego (USA) arriving at 18/12/2025 14:10:00. 50 Economy ticket for £190 per person are available. Travel duration is 46h 0m
Cheapest Buses Tuesday
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Greyhound US34h 30m006:10San Antonio, TXCoach Station14:40San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 18/12/2025 06:10:00 to San Ysidro Transit Center, San Diego (USA) arriving at 19/12/2025 14:40:00. 50 Economy ticket for £180 per person are available. Travel duration is 34h 30m
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FlixBus47h 5m021:15San Antonio, TXCoach Station18:20San DiegoSan Ysidro Transit Center0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 18/12/2025 21:15:00 to San Ysidro Transit Center, San Diego (USA) arriving at 20/12/2025 18:20:00. 50 Economy ticket for £213 per person are available. Travel duration is 47h 5m
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FlixBus42h 25m018:10San Antonio, TXCoach Station10:35San DiegoSan Ysidro Transit Center0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 18/12/2025 18:10:00 to San Ysidro Transit Center, San Diego (USA) arriving at 20/12/2025 10:35:00. 50 Economy ticket for £223 per person are available. Travel duration is 42h 25m
Cheapest Buses Thursday
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Greyhound US34h 0m006:10San Antonio, TXCoach Station14:10San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 19/12/2025 06:10:00 to Old Town Transit Center, San Diego (USA) arriving at 20/12/2025 14:10:00. 50 Economy ticket for £137 per person are available. Travel duration is 34h 0m
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Greyhound US33h 30m006:10San Antonio, TXCoach Station13:40San DiegoLa Jolla Village0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 19/12/2025 06:10:00 to La Jolla Village, San Diego (USA) arriving at 20/12/2025 13:40:00. 50 Economy ticket for £138 per person are available. Travel duration is 33h 30m
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Greyhound US42h 5m006:10San Antonio, TXCoach Station22:15San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 19/12/2025 06:10:00 to Seaport Village, San Diego (USA) arriving at 20/12/2025 22:15:00. 50 Economy ticket for £189 per person are available. Travel duration is 42h 5m
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FlixBus51h 0m021:15San Antonio, TXCoach Station22:15San DiegoSeaport Village0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 19/12/2025 21:15:00 to Seaport Village, San Diego (USA) arriving at 21/12/2025 22:15:00. 50 Economy ticket for £200 per person are available. Travel duration is 51h 0m
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FlixBus46h 30m021:15San Antonio, TXCoach Station17:45San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 19/12/2025 21:15:00 to Old Town Transit Center, San Diego (USA) arriving at 21/12/2025 17:45:00. 50 Economy ticket for £203 per person are available. Travel duration is 46h 30m
Cheapest Buses Friday
What are the fastest trips from San Antonio, TX to San Diego?
You can get to San Diego from San Antonio, TX in just 33h 30m with a Bus from Greyhound US. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Greyhound US37h 0m006:10San Antonio, TXCoach Station17:10San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 15/12/2025 06:10:00 to San Ysidro Transit Center, San Diego (USA) arriving at 16/12/2025 17:10:00. 50 Economy ticket for £148 per person are available. Travel duration is 37h 0m
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Greyhound US42h 5m006:10San Antonio, TXCoach Station22:15San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 15/12/2025 06:10:00 to Seaport Village, San Diego (USA) arriving at 16/12/2025 22:15:00. 50 Economy ticket for £148 per person are available. Travel duration is 42h 5m
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FlixBus43h 35m018:10San Antonio, TXCoach Station11:45San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 15/12/2025 18:10:00 to Old Town Transit Center, San Diego (USA) arriving at 17/12/2025 11:45:00. 50 Economy ticket for £148 per person are available. Travel duration is 43h 35m
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Greyhound Lines Mexico48h 55m019:15San Antonio, TXCoach Station18:10San DiegoOld Town Transit Center0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 15/12/2025 19:15:00 to Old Town Transit Center, San Diego (USA) arriving at 17/12/2025 18:10:00. 50 Economy ticket for £124 per person are available. Travel duration is 48h 55m
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Greyhound Lines Mexico53h 0m019:15San Antonio, TXCoach Station22:15San DiegoSeaport Village0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 15/12/2025 19:15:00 to Seaport Village, San Diego (USA) arriving at 17/12/2025 22:15:00. 50 Economy ticket for £124 per person are available. Travel duration is 53h 0m
Fastest Buses Monday
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Greyhound Lines Mexico42h 40m006:05San Antonio, TXCoach Station22:45San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 16/12/2025 06:05:00 to San Ysidro Transit Center, San Diego (USA) arriving at 17/12/2025 22:45:00. 50 Economy ticket for £172 per person are available. Travel duration is 42h 40m
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Greyhound Lines Mexico43h 15m001:30San Antonio, TXCoach Station18:45San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 16/12/2025 01:30:00 to San Ysidro Transit Center, San Diego (USA) arriving at 17/12/2025 18:45:00. 50 Economy ticket for £159 per person are available. Travel duration is 43h 15m
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FlixBus44h 10m018:10San Antonio, TXCoach Station12:20San DiegoSan Ysidro Transit Center0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 16/12/2025 18:10:00 to San Ysidro Transit Center, San Diego (USA) arriving at 18/12/2025 12:20:00. 50 Economy ticket for £164 per person are available. Travel duration is 44h 10m
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FlixBus46h 0m018:10San Antonio, TXCoach Station14:10San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 16/12/2025 18:10:00 to Old Town Transit Center, San Diego (USA) arriving at 18/12/2025 14:10:00. 50 Economy ticket for £190 per person are available. Travel duration is 46h 0m
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Greyhound Lines Mexico49h 30m019:15San Antonio, TXCoach Station18:45San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 16/12/2025 19:15:00 to San Ysidro Transit Center, San Diego (USA) arriving at 18/12/2025 18:45:00. 50 Economy ticket for £186 per person are available. Travel duration is 49h 30m
Fastest Buses Tuesday
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Greyhound US34h 30m006:10San Antonio, TXCoach Station14:40San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 18/12/2025 06:10:00 to San Ysidro Transit Center, San Diego (USA) arriving at 19/12/2025 14:40:00. 50 Economy ticket for £180 per person are available. Travel duration is 34h 30m
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FlixBus42h 25m018:10San Antonio, TXCoach Station10:35San DiegoSan Ysidro Transit Center0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 18/12/2025 18:10:00 to San Ysidro Transit Center, San Diego (USA) arriving at 20/12/2025 10:35:00. 50 Economy ticket for £223 per person are available. Travel duration is 42h 25m
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FlixBus47h 5m021:15San Antonio, TXCoach Station18:20San DiegoSan Ysidro Transit Center0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 18/12/2025 21:15:00 to San Ysidro Transit Center, San Diego (USA) arriving at 20/12/2025 18:20:00. 50 Economy ticket for £213 per person are available. Travel duration is 47h 5m
Fastest Buses Thursday
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Greyhound US33h 30m006:10San Antonio, TXCoach Station13:40San DiegoLa Jolla Village0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 19/12/2025 06:10:00 to La Jolla Village, San Diego (USA) arriving at 20/12/2025 13:40:00. 50 Economy ticket for £138 per person are available. Travel duration is 33h 30m
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Greyhound US34h 0m006:10San Antonio, TXCoach Station14:10San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 19/12/2025 06:10:00 to Old Town Transit Center, San Diego (USA) arriving at 20/12/2025 14:10:00. 50 Economy ticket for £137 per person are available. Travel duration is 34h 0m
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Greyhound US42h 5m006:10San Antonio, TXCoach Station22:15San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 19/12/2025 06:10:00 to Seaport Village, San Diego (USA) arriving at 20/12/2025 22:15:00. 50 Economy ticket for £189 per person are available. Travel duration is 42h 5m
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FlixBus46h 30m021:15San Antonio, TXCoach Station17:45San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 19/12/2025 21:15:00 to Old Town Transit Center, San Diego (USA) arriving at 21/12/2025 17:45:00. 50 Economy ticket for £203 per person are available. Travel duration is 46h 30m
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FlixBus51h 0m021:15San Antonio, TXCoach Station22:15San DiegoSeaport Village0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 19/12/2025 21:15:00 to Seaport Village, San Diego (USA) arriving at 21/12/2025 22:15:00. 50 Economy ticket for £200 per person are available. Travel duration is 51h 0m
Fastest Buses Friday
Here you will find all operators and timetables for a
Bus from San Antonio, TX to San Diego
What are the most popular stations in San Antonio, TX and San Diego?
In San Antonio, TX, you will usually depart from Tornado Bus Company, Coach Station or W. Southcross & Buffalo Bus Stop, while in San Diego you will be arriving at San Ysidro Transit Center, University Av & Bancroft St Coach Stop or Old Town Transit Center, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to San Diego from San Antonio, TX? With 4 connections between 3 Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between San Antonio, TX and San Diego, you can pay as low as £124 with a Bus from Greyhound Lines Mexico.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Bus from Greyhound US: you will get to San Diego in just 33h 30m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting San Antonio, TX and San Diego are FlixBus, Greyhound US and Greyhound Lines Mexico, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in San Antonio, TX and San Diego is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Olmos Park, TX or to San Diego Airport, and look at flights from San Antonio Airport, and landing at Tijuana Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from San Antonio, TX to San Diego?
The most popular companies between San Antonio, TX and San Diego, are FlixBus, Greyhound US and Greyhound Lines Mexico. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus, Greyhound US and Greyhound Lines Mexico
All you need to know when you travel from San Antonio, TX to San Diego
Check all information on comfort and services on all modes of transports from San Antonio, TX to San Diego. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from San Antonio, TX to San Diego
How can I reach San Diego from San Antonio, TX?
Every day, there are on average 4 connections between Bus, with which you can get to San Diego from San Antonio, TX.
How far is San Diego from San Antonio, TX?
The distance between San Antonio, TX and San Diego is 1,812.4 km.
What is the most ecofriendly mode of transport between San Antonio, TX and San Diego?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 49 kgs of CO2, a train 63 kgs, a car 308 kgs, and a flight 446 kgs.
What is the cheapest mode of transport from San Antonio, TX to San Diego?
You can get to San Diego with just £124 by taking a Bus from Greyhound Lines Mexico.
What is the fastest way to get from San Antonio, TX to San Diego?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to San Diego in just 33h 30m with a Bus from Greyhound US.
More routes to San Antonio, TX and to San Diego
Looking for more options? Here you can see the most popular routes to San Antonio, TX and to San Diego. Simply click on a connection, and you’ll find all the details about the route!
- Trips to San Antonio, TX
- Aguascalientes to San Antonio, TX
- Brownsville, TX to San Antonio, TX
- Chicago to San Antonio, TX
- Ciudad Juárez to San Antonio, TX
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- Guadalajara, JC to San Antonio, TX
- Houston to San Antonio, TX
- Las Vegas to San Antonio, TX
- Los Angeles to San Antonio, TX
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- Mexico City to San Antonio, TX
- Monterrey, NL to San Antonio, TX
- New Orleans, LA to San Antonio, TX
- Orlando, FL to San Antonio, TX
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