What is the best way to travel from Portland, OR to San Diego?
Looking for a trip? Check and compare all the available Buses and Flights to San Diego from Portland, OR. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 3 available companies to find your perfect trip!
What is the cheapest way to reach San Diego from Portland, OR?
You can reach San Diego with just £103 by taking a Flight from Frontier Airlines, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Alaska Airlines2h 32m007:17Portland, OR AirportPortland, OR Airport09:49San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 15/12/2025 07:17:00 to San Diego Airport, San Diego Airport (USA) arriving at 15/12/2025 09:49:00. 50 Economy ticket for £178 per person are available. Travel duration is 2h 32m
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Alaska Airlines2h 29m010:30Portland, OR AirportPortland, OR Airport12:59San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 15/12/2025 10:30:00 to San Diego Airport, San Diego Airport (USA) arriving at 15/12/2025 12:59:00. 50 Economy ticket for £178 per person are available. Travel duration is 2h 29m
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Skyscanner4h 45m007:08Portland, OR AirportPortland, OR Airport11:53San Diego AirportSan Diego Airport0EconomyA Flight from Skyscanner goes from Portland, OR Airport, Portland, OR Airport (USA) at 15/12/2025 07:08:00 to San Diego Airport, San Diego Airport (USA) arriving at 15/12/2025 11:53:00. 50 Economy ticket for £198 per person are available. Travel duration is 4h 45m
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Skyscanner3h 47m010:38Portland, OR AirportPortland, OR Airport14:25San Diego AirportSan Diego Airport0EconomyA Flight from Skyscanner goes from Portland, OR Airport, Portland, OR Airport (USA) at 15/12/2025 10:38:00 to San Diego Airport, San Diego Airport (USA) arriving at 15/12/2025 14:25:00. 50 Economy ticket for £198 per person are available. Travel duration is 3h 47m
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United Airlines8h 4m005:00Portland, OR AirportPortland, OR Airport13:04San Diego AirportSan Diego Airport0EconomyA Flight from United Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 15/12/2025 05:00:00 to San Diego Airport, San Diego Airport (USA) arriving at 15/12/2025 13:04:00. 50 Economy ticket for £206 per person are available. Travel duration is 8h 4m
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Alaska Airlines9h 40m007:30Portland, OR AirportPortland, OR Airport17:10Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 15/12/2025 07:30:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 15/12/2025 17:10:00. 50 Economy ticket for £321 per person are available. Travel duration is 9h 40m
Cheapest Flights Monday
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Greyhound US34h 20m002:00Portland, ORUnion Coach Station12:20San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Union Coach Station, Portland, OR (USA) at 17/12/2025 02:00:00 to San Ysidro Transit Center, San Diego (USA) arriving at 18/12/2025 12:20:00. 50 Economy ticket for £121 per person are available. Travel duration is 34h 20m
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FlixBus28h 35m019:50Portland, ORUnion Coach Station00:25San DiegoSan Ysidro Transit Center0EconomyA Bus from FlixBus goes from Union Coach Station, Portland, OR (USA) at 17/12/2025 19:50:00 to San Ysidro Transit Center, San Diego (USA) arriving at 19/12/2025 00:25:00. 50 Economy ticket for £121 per person are available. Travel duration is 28h 35m
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Alaska Airlines9h 55m007:15Portland, OR AirportPortland, OR Airport17:10Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 17/12/2025 07:15:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 17/12/2025 17:10:00. 50 Economy ticket for £267 per person are available. Travel duration is 9h 55m
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Alaska Airlines12h 30m007:15Portland, OR AirportPortland, OR Airport19:45Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 17/12/2025 07:15:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 17/12/2025 19:45:00. 50 Economy ticket for £273 per person are available. Travel duration is 12h 30m
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Volaris9h 14m023:18Portland, OR AirportPortland, OR Airport08:32Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Portland, OR Airport, Portland, OR Airport (USA) at 17/12/2025 23:18:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 18/12/2025 08:32:00. 50 Economy ticket for £465 per person are available. Travel duration is 9h 14m
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Volaris12h 53m017:36Portland, OR AirportPortland, OR Airport06:29Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Portland, OR Airport, Portland, OR Airport (USA) at 17/12/2025 17:36:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 18/12/2025 06:29:00. 50 Economy ticket for £526 per person are available. Travel duration is 12h 53m
Cheapest Buses Wednesday
Cheapest Flights Wednesday
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Frontier Airlines11h 12m012:47Portland, OR AirportPortland, OR Airport23:59San Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 18/12/2025 12:47:00 to San Diego Airport, San Diego Airport (USA) arriving at 18/12/2025 23:59:00. 50 Economy ticket for £103 per person are available. Travel duration is 11h 12m
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Frontier Airlines6h 28m012:47Portland, OR AirportPortland, OR Airport19:15San Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 18/12/2025 12:47:00 to San Diego Airport, San Diego Airport (USA) arriving at 18/12/2025 19:15:00. 50 Economy ticket for £121 per person are available. Travel duration is 6h 28m
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Alaska Airlines4h 49m007:01Portland, OR AirportPortland, OR Airport11:50San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 18/12/2025 07:01:00 to San Diego Airport, San Diego Airport (USA) arriving at 18/12/2025 11:50:00. 50 Economy ticket for £167 per person are available. Travel duration is 4h 49m
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Alaska Airlines5h 5m014:31Portland, OR AirportPortland, OR Airport19:36San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 18/12/2025 14:31:00 to San Diego Airport, San Diego Airport (USA) arriving at 18/12/2025 19:36:00. 50 Economy ticket for £167 per person are available. Travel duration is 5h 5m
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Skyscanner4h 44m007:05Portland, OR AirportPortland, OR Airport11:49San Diego AirportSan Diego Airport0EconomyA Flight from Skyscanner goes from Portland, OR Airport, Portland, OR Airport (USA) at 18/12/2025 07:05:00 to San Diego Airport, San Diego Airport (USA) arriving at 18/12/2025 11:49:00. 50 Economy ticket for £197 per person are available. Travel duration is 4h 44m
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Alaska Airlines9h 28m010:30Portland, OR AirportPortland, OR Airport19:58Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 18/12/2025 10:30:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 18/12/2025 19:58:00. 50 Economy ticket for £357 per person are available. Travel duration is 9h 28m
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Greyhound US44h 15m002:00Portland, ORUnion Coach Station22:15San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Union Coach Station, Portland, OR (USA) at 18/12/2025 02:00:00 to Seaport Village, San Diego (USA) arriving at 19/12/2025 22:15:00. 50 Economy ticket for £157 per person are available. Travel duration is 44h 15m
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Greyhound US38h 25m002:00Portland, ORUnion Coach Station16:25San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Union Coach Station, Portland, OR (USA) at 18/12/2025 02:00:00 to Old Town Transit Center, San Diego (USA) arriving at 19/12/2025 16:25:00. 50 Economy ticket for £158 per person are available. Travel duration is 38h 25m
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Greyhound US37h 55m002:00Portland, ORUnion Coach Station15:55San DiegoLa Jolla Village0EconomyA Bus from Greyhound US goes from Union Coach Station, Portland, OR (USA) at 18/12/2025 02:00:00 to La Jolla Village, San Diego (USA) arriving at 19/12/2025 15:55:00. 50 Economy ticket for £158 per person are available. Travel duration is 37h 55m
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FlixBus50h 15m020:00Portland, ORUnion Coach Station22:15San DiegoSeaport Village0EconomyA Bus from FlixBus goes from Union Coach Station, Portland, OR (USA) at 18/12/2025 20:00:00 to Seaport Village, San Diego (USA) arriving at 20/12/2025 22:15:00. 50 Economy ticket for £173 per person are available. Travel duration is 50h 15m
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FlixBus44h 25m020:00Portland, ORUnion Coach Station16:25San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Union Coach Station, Portland, OR (USA) at 18/12/2025 20:00:00 to Old Town Transit Center, San Diego (USA) arriving at 20/12/2025 16:25:00. 50 Economy ticket for £175 per person are available. Travel duration is 44h 25m
Cheapest Flights Thursday
Cheapest Buses Thursday
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Alaska Airlines2h 37m007:03Portland, OR AirportPortland, OR Airport09:40San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 20/12/2025 07:03:00 to San Diego Airport, San Diego Airport (USA) arriving at 20/12/2025 09:40:00. 50 Economy ticket for £188 per person are available. Travel duration is 2h 37m
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Alaska Airlines2h 36m010:30Portland, OR AirportPortland, OR Airport13:06San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 20/12/2025 10:30:00 to San Diego Airport, San Diego Airport (USA) arriving at 20/12/2025 13:06:00. 50 Economy ticket for £188 per person are available. Travel duration is 2h 36m
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Skyscanner4h 44m007:05Portland, OR AirportPortland, OR Airport11:49San Diego AirportSan Diego Airport0EconomyA Flight from Skyscanner goes from Portland, OR Airport, Portland, OR Airport (USA) at 20/12/2025 07:05:00 to San Diego Airport, San Diego Airport (USA) arriving at 20/12/2025 11:49:00. 50 Economy ticket for £195 per person are available. Travel duration is 4h 44m
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Skyscanner6h 39m014:50Portland, OR AirportPortland, OR Airport21:29San Diego AirportSan Diego Airport0EconomyA Flight from Skyscanner goes from Portland, OR Airport, Portland, OR Airport (USA) at 20/12/2025 14:50:00 to San Diego Airport, San Diego Airport (USA) arriving at 20/12/2025 21:29:00. 50 Economy ticket for £195 per person are available. Travel duration is 6h 39m
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United Airlines7h 28m007:30Portland, OR AirportPortland, OR Airport14:58San Diego AirportSan Diego Airport0EconomyA Flight from United Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 20/12/2025 07:30:00 to San Diego Airport, San Diego Airport (USA) arriving at 20/12/2025 14:58:00. 50 Economy ticket for £205 per person are available. Travel duration is 7h 28m
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Volaris9h 14m023:18Portland, OR AirportPortland, OR Airport08:32Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Portland, OR Airport, Portland, OR Airport (USA) at 20/12/2025 23:18:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 21/12/2025 08:32:00. 50 Economy ticket for £660 per person are available. Travel duration is 9h 14m
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Greyhound US38h 25m002:00Portland, ORGreyhound Bus Station16:25San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 20/12/2025 02:00:00 to Old Town Transit Center, San Diego (USA) arriving at 21/12/2025 16:25:00. 50 Economy ticket for £279 per person are available. Travel duration is 38h 25m
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Greyhound US44h 15m002:00Portland, ORGreyhound Bus Station22:15San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 20/12/2025 02:00:00 to Seaport Village, San Diego (USA) arriving at 21/12/2025 22:15:00. 50 Economy ticket for £280 per person are available. Travel duration is 44h 15m
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FlixBus27h 50m020:00Portland, ORGreyhound Bus Station23:50San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Greyhound Bus Station, Portland, OR (USA) at 20/12/2025 20:00:00 to Old Town Transit Center, San Diego (USA) arriving at 21/12/2025 23:50:00. 50 Economy ticket for £313 per person are available. Travel duration is 27h 50m
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FlixBus44h 25m020:00Portland, ORGreyhound Bus Station16:25San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Greyhound Bus Station, Portland, OR (USA) at 20/12/2025 20:00:00 to Old Town Transit Center, San Diego (USA) arriving at 22/12/2025 16:25:00. 50 Economy ticket for £313 per person are available. Travel duration is 44h 25m
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FlixBus50h 15m020:00Portland, ORGreyhound Bus Station22:15San DiegoSeaport Village0EconomyA Bus from FlixBus goes from Greyhound Bus Station, Portland, OR (USA) at 20/12/2025 20:00:00 to Seaport Village, San Diego (USA) arriving at 22/12/2025 22:15:00. 50 Economy ticket for £314 per person are available. Travel duration is 50h 15m
Cheapest Flights Saturday
Cheapest Buses Saturday
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Alaska Airlines2h 37m007:03Portland, OR AirportPortland, OR Airport09:40San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 21/12/2025 07:03:00 to San Diego Airport, San Diego Airport (USA) arriving at 21/12/2025 09:40:00. 50 Economy ticket for £189 per person are available. Travel duration is 2h 37m
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Alaska Airlines2h 33m020:34Portland, OR AirportPortland, OR Airport23:07San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 21/12/2025 20:34:00 to San Diego Airport, San Diego Airport (USA) arriving at 21/12/2025 23:07:00. 50 Economy ticket for £189 per person are available. Travel duration is 2h 33m
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Frontier Airlines6h 28m012:47Portland, OR AirportPortland, OR Airport19:15San Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 21/12/2025 12:47:00 to San Diego Airport, San Diego Airport (USA) arriving at 21/12/2025 19:15:00. 50 Economy ticket for £195 per person are available. Travel duration is 6h 28m
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Frontier Airlines22h 19m014:19Portland, OR AirportPortland, OR Airport12:38San Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 21/12/2025 14:19:00 to San Diego Airport, San Diego Airport (USA) arriving at 22/12/2025 12:38:00. 50 Economy ticket for £199 per person are available. Travel duration is 22h 19m
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United Airlines5h 32m007:30Portland, OR AirportPortland, OR Airport13:02San Diego AirportSan Diego Airport0EconomyA Flight from United Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 21/12/2025 07:30:00 to San Diego Airport, San Diego Airport (USA) arriving at 21/12/2025 13:02:00. 50 Economy ticket for £206 per person are available. Travel duration is 5h 32m
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Alaska Airlines9h 18m010:30Portland, OR AirportPortland, OR Airport19:48Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 21/12/2025 10:30:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 21/12/2025 19:48:00. 50 Economy ticket for £411 per person are available. Travel duration is 9h 18m
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Greyhound US44h 15m002:00Portland, ORGreyhound Bus Station22:15San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 21/12/2025 02:00:00 to Seaport Village, San Diego (USA) arriving at 22/12/2025 22:15:00. 50 Economy ticket for £194 per person are available. Travel duration is 44h 15m
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Greyhound US38h 25m002:00Portland, ORGreyhound Bus Station16:25San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 21/12/2025 02:00:00 to Old Town Transit Center, San Diego (USA) arriving at 22/12/2025 16:25:00. 50 Economy ticket for £194 per person are available. Travel duration is 38h 25m
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FlixBus27h 50m020:00Portland, ORGreyhound Bus Station23:50San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Greyhound Bus Station, Portland, OR (USA) at 21/12/2025 20:00:00 to Old Town Transit Center, San Diego (USA) arriving at 22/12/2025 23:50:00. 50 Economy ticket for £194 per person are available. Travel duration is 27h 50m
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FlixBus50h 15m020:00Portland, ORGreyhound Bus Station22:15San DiegoSeaport Village0EconomyA Bus from FlixBus goes from Greyhound Bus Station, Portland, OR (USA) at 21/12/2025 20:00:00 to Seaport Village, San Diego (USA) arriving at 23/12/2025 22:15:00. 50 Economy ticket for £195 per person are available. Travel duration is 50h 15m
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Greyhound US44h 15m002:00Portland, ORUnion Coach Station22:15San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Union Coach Station, Portland, OR (USA) at 21/12/2025 02:00:00 to Seaport Village, San Diego (USA) arriving at 22/12/2025 22:15:00. 50 Economy ticket for £196 per person are available. Travel duration is 44h 15m
Cheapest Flights Sunday
Cheapest Buses Sunday
What are the fastest trips from Portland, OR to San Diego?
You can get to San Diego from Portland, OR in just 2h 29m with a Flight from Alaska Airlines. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Alaska Airlines2h 29m010:30Portland, OR AirportPortland, OR Airport12:59San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 15/12/2025 10:30:00 to San Diego Airport, San Diego Airport (USA) arriving at 15/12/2025 12:59:00. 50 Economy ticket for £178 per person are available. Travel duration is 2h 29m
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Alaska Airlines2h 32m007:17Portland, OR AirportPortland, OR Airport09:49San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 15/12/2025 07:17:00 to San Diego Airport, San Diego Airport (USA) arriving at 15/12/2025 09:49:00. 50 Economy ticket for £178 per person are available. Travel duration is 2h 32m
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Skyscanner3h 47m010:38Portland, OR AirportPortland, OR Airport14:25San Diego AirportSan Diego Airport0EconomyA Flight from Skyscanner goes from Portland, OR Airport, Portland, OR Airport (USA) at 15/12/2025 10:38:00 to San Diego Airport, San Diego Airport (USA) arriving at 15/12/2025 14:25:00. 50 Economy ticket for £198 per person are available. Travel duration is 3h 47m
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Skyscanner4h 45m007:08Portland, OR AirportPortland, OR Airport11:53San Diego AirportSan Diego Airport0EconomyA Flight from Skyscanner goes from Portland, OR Airport, Portland, OR Airport (USA) at 15/12/2025 07:08:00 to San Diego Airport, San Diego Airport (USA) arriving at 15/12/2025 11:53:00. 50 Economy ticket for £198 per person are available. Travel duration is 4h 45m
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United Airlines8h 4m005:00Portland, OR AirportPortland, OR Airport13:04San Diego AirportSan Diego Airport0EconomyA Flight from United Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 15/12/2025 05:00:00 to San Diego Airport, San Diego Airport (USA) arriving at 15/12/2025 13:04:00. 50 Economy ticket for £206 per person are available. Travel duration is 8h 4m
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Volaris9h 14m023:18Portland, OR AirportPortland, OR Airport08:32Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Portland, OR Airport, Portland, OR Airport (USA) at 15/12/2025 23:18:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 16/12/2025 08:32:00. 50 Economy ticket for £519 per person are available. Travel duration is 9h 14m
Fastest Flights Monday
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Volaris9h 14m023:18Portland, OR AirportPortland, OR Airport08:32Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Portland, OR Airport, Portland, OR Airport (USA) at 17/12/2025 23:18:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 18/12/2025 08:32:00. 50 Economy ticket for £465 per person are available. Travel duration is 9h 14m
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Alaska Airlines9h 55m007:15Portland, OR AirportPortland, OR Airport17:10Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 17/12/2025 07:15:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 17/12/2025 17:10:00. 50 Economy ticket for £267 per person are available. Travel duration is 9h 55m
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Alaska Airlines12h 30m007:15Portland, OR AirportPortland, OR Airport19:45Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 17/12/2025 07:15:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 17/12/2025 19:45:00. 50 Economy ticket for £273 per person are available. Travel duration is 12h 30m
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Volaris12h 53m017:36Portland, OR AirportPortland, OR Airport06:29Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Portland, OR Airport, Portland, OR Airport (USA) at 17/12/2025 17:36:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 18/12/2025 06:29:00. 50 Economy ticket for £526 per person are available. Travel duration is 12h 53m
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FlixBus28h 35m019:50Portland, ORUnion Coach Station00:25San DiegoSan Ysidro Transit Center0EconomyA Bus from FlixBus goes from Union Coach Station, Portland, OR (USA) at 17/12/2025 19:50:00 to San Ysidro Transit Center, San Diego (USA) arriving at 19/12/2025 00:25:00. 50 Economy ticket for £121 per person are available. Travel duration is 28h 35m
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Greyhound US34h 20m002:00Portland, ORUnion Coach Station12:20San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Union Coach Station, Portland, OR (USA) at 17/12/2025 02:00:00 to San Ysidro Transit Center, San Diego (USA) arriving at 18/12/2025 12:20:00. 50 Economy ticket for £121 per person are available. Travel duration is 34h 20m
Fastest Flights Wednesday
Fastest Buses Wednesday
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Skyscanner4h 44m007:05Portland, OR AirportPortland, OR Airport11:49San Diego AirportSan Diego Airport0EconomyA Flight from Skyscanner goes from Portland, OR Airport, Portland, OR Airport (USA) at 18/12/2025 07:05:00 to San Diego Airport, San Diego Airport (USA) arriving at 18/12/2025 11:49:00. 50 Economy ticket for £197 per person are available. Travel duration is 4h 44m
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Alaska Airlines4h 49m007:01Portland, OR AirportPortland, OR Airport11:50San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 18/12/2025 07:01:00 to San Diego Airport, San Diego Airport (USA) arriving at 18/12/2025 11:50:00. 50 Economy ticket for £167 per person are available. Travel duration is 4h 49m
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Alaska Airlines5h 5m014:31Portland, OR AirportPortland, OR Airport19:36San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 18/12/2025 14:31:00 to San Diego Airport, San Diego Airport (USA) arriving at 18/12/2025 19:36:00. 50 Economy ticket for £167 per person are available. Travel duration is 5h 5m
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Frontier Airlines6h 28m012:47Portland, OR AirportPortland, OR Airport19:15San Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 18/12/2025 12:47:00 to San Diego Airport, San Diego Airport (USA) arriving at 18/12/2025 19:15:00. 50 Economy ticket for £121 per person are available. Travel duration is 6h 28m
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Volaris9h 14m023:18Portland, OR AirportPortland, OR Airport08:32Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Portland, OR Airport, Portland, OR Airport (USA) at 18/12/2025 23:18:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 19/12/2025 08:32:00. 50 Economy ticket for £667 per person are available. Travel duration is 9h 14m
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Alaska Airlines9h 28m010:30Portland, OR AirportPortland, OR Airport19:58Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 18/12/2025 10:30:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 18/12/2025 19:58:00. 50 Economy ticket for £357 per person are available. Travel duration is 9h 28m
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Greyhound US37h 55m002:00Portland, ORUnion Coach Station15:55San DiegoLa Jolla Village0EconomyA Bus from Greyhound US goes from Union Coach Station, Portland, OR (USA) at 18/12/2025 02:00:00 to La Jolla Village, San Diego (USA) arriving at 19/12/2025 15:55:00. 50 Economy ticket for £158 per person are available. Travel duration is 37h 55m
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Greyhound US38h 25m002:00Portland, ORUnion Coach Station16:25San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Union Coach Station, Portland, OR (USA) at 18/12/2025 02:00:00 to Old Town Transit Center, San Diego (USA) arriving at 19/12/2025 16:25:00. 50 Economy ticket for £158 per person are available. Travel duration is 38h 25m
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Greyhound US44h 15m002:00Portland, ORUnion Coach Station22:15San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Union Coach Station, Portland, OR (USA) at 18/12/2025 02:00:00 to Seaport Village, San Diego (USA) arriving at 19/12/2025 22:15:00. 50 Economy ticket for £157 per person are available. Travel duration is 44h 15m
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FlixBus44h 25m020:00Portland, ORUnion Coach Station16:25San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Union Coach Station, Portland, OR (USA) at 18/12/2025 20:00:00 to Old Town Transit Center, San Diego (USA) arriving at 20/12/2025 16:25:00. 50 Economy ticket for £175 per person are available. Travel duration is 44h 25m
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FlixBus50h 15m020:00Portland, ORUnion Coach Station22:15San DiegoSeaport Village0EconomyA Bus from FlixBus goes from Union Coach Station, Portland, OR (USA) at 18/12/2025 20:00:00 to Seaport Village, San Diego (USA) arriving at 20/12/2025 22:15:00. 50 Economy ticket for £173 per person are available. Travel duration is 50h 15m
Fastest Flights Thursday
Fastest Buses Thursday
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Alaska Airlines2h 36m010:30Portland, OR AirportPortland, OR Airport13:06San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 20/12/2025 10:30:00 to San Diego Airport, San Diego Airport (USA) arriving at 20/12/2025 13:06:00. 50 Economy ticket for £188 per person are available. Travel duration is 2h 36m
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Alaska Airlines2h 37m007:03Portland, OR AirportPortland, OR Airport09:40San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 20/12/2025 07:03:00 to San Diego Airport, San Diego Airport (USA) arriving at 20/12/2025 09:40:00. 50 Economy ticket for £188 per person are available. Travel duration is 2h 37m
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Skyscanner4h 44m007:05Portland, OR AirportPortland, OR Airport11:49San Diego AirportSan Diego Airport0EconomyA Flight from Skyscanner goes from Portland, OR Airport, Portland, OR Airport (USA) at 20/12/2025 07:05:00 to San Diego Airport, San Diego Airport (USA) arriving at 20/12/2025 11:49:00. 50 Economy ticket for £195 per person are available. Travel duration is 4h 44m
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Skyscanner6h 39m014:50Portland, OR AirportPortland, OR Airport21:29San Diego AirportSan Diego Airport0EconomyA Flight from Skyscanner goes from Portland, OR Airport, Portland, OR Airport (USA) at 20/12/2025 14:50:00 to San Diego Airport, San Diego Airport (USA) arriving at 20/12/2025 21:29:00. 50 Economy ticket for £195 per person are available. Travel duration is 6h 39m
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United Airlines7h 28m007:30Portland, OR AirportPortland, OR Airport14:58San Diego AirportSan Diego Airport0EconomyA Flight from United Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 20/12/2025 07:30:00 to San Diego Airport, San Diego Airport (USA) arriving at 20/12/2025 14:58:00. 50 Economy ticket for £205 per person are available. Travel duration is 7h 28m
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Volaris9h 14m023:18Portland, OR AirportPortland, OR Airport08:32Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Portland, OR Airport, Portland, OR Airport (USA) at 20/12/2025 23:18:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 21/12/2025 08:32:00. 50 Economy ticket for £660 per person are available. Travel duration is 9h 14m
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FlixBus27h 50m020:00Portland, ORGreyhound Bus Station23:50San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Greyhound Bus Station, Portland, OR (USA) at 20/12/2025 20:00:00 to Old Town Transit Center, San Diego (USA) arriving at 21/12/2025 23:50:00. 50 Economy ticket for £313 per person are available. Travel duration is 27h 50m
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Greyhound US38h 25m002:00Portland, ORGreyhound Bus Station16:25San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 20/12/2025 02:00:00 to Old Town Transit Center, San Diego (USA) arriving at 21/12/2025 16:25:00. 50 Economy ticket for £279 per person are available. Travel duration is 38h 25m
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Greyhound US44h 15m002:00Portland, ORGreyhound Bus Station22:15San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 20/12/2025 02:00:00 to Seaport Village, San Diego (USA) arriving at 21/12/2025 22:15:00. 50 Economy ticket for £280 per person are available. Travel duration is 44h 15m
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FlixBus44h 25m020:00Portland, ORGreyhound Bus Station16:25San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Greyhound Bus Station, Portland, OR (USA) at 20/12/2025 20:00:00 to Old Town Transit Center, San Diego (USA) arriving at 22/12/2025 16:25:00. 50 Economy ticket for £313 per person are available. Travel duration is 44h 25m
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FlixBus50h 15m020:00Portland, ORGreyhound Bus Station22:15San DiegoSeaport Village0EconomyA Bus from FlixBus goes from Greyhound Bus Station, Portland, OR (USA) at 20/12/2025 20:00:00 to Seaport Village, San Diego (USA) arriving at 22/12/2025 22:15:00. 50 Economy ticket for £314 per person are available. Travel duration is 50h 15m
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Alaska Airlines2h 33m020:34Portland, OR AirportPortland, OR Airport23:07San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 21/12/2025 20:34:00 to San Diego Airport, San Diego Airport (USA) arriving at 21/12/2025 23:07:00. 50 Economy ticket for £189 per person are available. Travel duration is 2h 33m
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Alaska Airlines2h 37m007:03Portland, OR AirportPortland, OR Airport09:40San Diego AirportSan Diego Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 21/12/2025 07:03:00 to San Diego Airport, San Diego Airport (USA) arriving at 21/12/2025 09:40:00. 50 Economy ticket for £189 per person are available. Travel duration is 2h 37m
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United Airlines5h 32m007:30Portland, OR AirportPortland, OR Airport13:02San Diego AirportSan Diego Airport0EconomyA Flight from United Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 21/12/2025 07:30:00 to San Diego Airport, San Diego Airport (USA) arriving at 21/12/2025 13:02:00. 50 Economy ticket for £206 per person are available. Travel duration is 5h 32m
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Frontier Airlines6h 28m012:47Portland, OR AirportPortland, OR Airport19:15San Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 21/12/2025 12:47:00 to San Diego Airport, San Diego Airport (USA) arriving at 21/12/2025 19:15:00. 50 Economy ticket for £195 per person are available. Travel duration is 6h 28m
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Alaska Airlines9h 15m010:30Portland, OR AirportPortland, OR Airport19:45Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 21/12/2025 10:30:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 21/12/2025 19:45:00. 50 Economy ticket for £446 per person are available. Travel duration is 9h 15m
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Alaska Airlines9h 18m010:30Portland, OR AirportPortland, OR Airport19:48Tijuana AirportTijuana Airport0EconomyA Flight from Alaska Airlines goes from Portland, OR Airport, Portland, OR Airport (USA) at 21/12/2025 10:30:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 21/12/2025 19:48:00. 50 Economy ticket for £411 per person are available. Travel duration is 9h 18m
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FlixBus27h 50m020:00Portland, ORGreyhound Bus Station23:50San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Greyhound Bus Station, Portland, OR (USA) at 21/12/2025 20:00:00 to Old Town Transit Center, San Diego (USA) arriving at 22/12/2025 23:50:00. 50 Economy ticket for £194 per person are available. Travel duration is 27h 50m
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Greyhound US38h 25m002:00Portland, ORGreyhound Bus Station16:25San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 21/12/2025 02:00:00 to Old Town Transit Center, San Diego (USA) arriving at 22/12/2025 16:25:00. 50 Economy ticket for £194 per person are available. Travel duration is 38h 25m
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Greyhound US44h 15m002:00Portland, ORGreyhound Bus Station22:15San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 21/12/2025 02:00:00 to Seaport Village, San Diego (USA) arriving at 22/12/2025 22:15:00. 50 Economy ticket for £194 per person are available. Travel duration is 44h 15m
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Greyhound US44h 15m002:00Portland, ORUnion Coach Station22:15San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Union Coach Station, Portland, OR (USA) at 21/12/2025 02:00:00 to Seaport Village, San Diego (USA) arriving at 22/12/2025 22:15:00. 50 Economy ticket for £196 per person are available. Travel duration is 44h 15m
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FlixBus50h 15m020:00Portland, ORGreyhound Bus Station22:15San DiegoSeaport Village0EconomyA Bus from FlixBus goes from Greyhound Bus Station, Portland, OR (USA) at 21/12/2025 20:00:00 to Seaport Village, San Diego (USA) arriving at 23/12/2025 22:15:00. 50 Economy ticket for £195 per person are available. Travel duration is 50h 15m
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Here you will find all operators and timetables for a
Bus from Portland, OR to San Diego
What are the most popular stations in Portland, OR and San Diego?
In Portland, OR, you will usually depart from Greyhound Bus Station, SE 102nd & Washington Coach Stop or Union Coach Station, while in San Diego you will be arriving at San Ysidro Transit Center, University Av & Bancroft St Coach Stop or Old Town Transit Center, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to San Diego from Portland, OR? With 11 connections between 3 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Portland, OR and San Diego, you can pay as low as £103 with a Flight from Frontier Airlines.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Alaska Airlines: you will get to San Diego in just 2h 29m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Portland, OR and San Diego are Alaska Airlines, Greyhound US and FlixBus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Portland, OR and San Diego is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from West Haven-Sylvan, OR or to San Diego Airport, and look at flights from Portland, OR Airport, and landing at Tijuana Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Portland, OR to San Diego?
The most popular companies between Portland, OR and San Diego, are Alaska Airlines, Greyhound US and FlixBus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Greyhound US and FlixBus
Airlines: Alaska Airlines, Delta Air Lines, Volaris and 3 more.
All you need to know when you travel from Portland, OR to San Diego
Check all information on comfort and services on all modes of transports from Portland, OR to San Diego. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Portland, OR to San Diego
How can I reach San Diego from Portland, OR?
Every day, there are on average 11 connections between Bus and Flight, with which you can get to San Diego from Portland, OR.
How far is San Diego from Portland, OR?
The distance between Portland, OR and San Diego is 1,500.1 km.
What is the most ecofriendly mode of transport between Portland, OR and San Diego?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 41 kgs of CO2, a train 53 kgs, a car 255 kgs, and a flight 369 kgs.
What is the cheapest mode of transport from Portland, OR to San Diego?
You can get to San Diego with just £103 by taking a Flight from Frontier Airlines.
What is the fastest way to get from Portland, OR to San Diego?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to San Diego in just 2h 29m with a Flight from Alaska Airlines.
More routes to Portland, OR and to San Diego
Looking for more options? Here you can see the most popular routes to Portland, OR and to San Diego. Simply click on a connection, and you’ll find all the details about the route!

