How to get from Pittsburgh to St. Louis, MO

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What is the best way to travel from Pittsburgh to St. Louis, MO?

Looking for a trip? Check and compare all the available Buses and Flights to St. Louis, MO from Pittsburgh. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
Bus is the cheapest, while Flight is the fastest way on this route
Transport type
Travel time
Cheapest price
Average price
Daily departures
Bus
12h 55m
£52
£68
6
Flight
4h 42m
£158
£271
12

What is the cheapest way to reach St. Louis, MO from Pittsburgh?

You can reach St. Louis, MO with just £52 by taking a Bus from Greyhound US, but there are many more cheap offers: we have selected the best ones for you for the next few days here.

Monday
from £52
Tuesday
from £53
Wednesday
Thursday
from £158
Friday
Saturday
from £170
Sunday
from £75

    Cheapest Buses Monday

  • Greyhound US
    14h 45m
    0
    01:35
    Pittsburgh
    Grant Street Transportation Center
    15:20
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    £52
  • Greyhound US
    13h 35m
    0
    10:50
    Pittsburgh
    Grant Street Transportation Center
    23:25
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    £52
  • Greyhound US
    12h 55m
    0
    20:00
    Pittsburgh
    Grant Street Transportation Center
    07:55
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    £57
  • Cheapest Flights Monday

  • United Airlines
    5h 50m
    0
    06:00
    Pittsburgh Airport
    Pittsburgh Airport
    10:50
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from £335
  • Skyscanner
    7h 42m
    0
    17:00
    Pittsburgh Airport
    Pittsburgh Airport
    23:42
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Skyscanner
    Economy
    from £335
  • Skyscanner
    6h 10m
    0
    18:32
    Pittsburgh Airport
    Pittsburgh Airport
    23:42
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Skyscanner
    Economy
    from £335
  • Alaska Airlines
    19h 54m
    0
    19:33
    Pittsburgh Airport
    Pittsburgh Airport
    14:27
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Alaska Airlines
    Economy
    from £483

    Cheapest Buses Tuesday

  • Greyhound US
    14h 45m
    0
    01:35
    Pittsburgh
    Grant Street Transportation Center
    15:20
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    £53
  • Greyhound US
    12h 55m
    0
    20:00
    Pittsburgh
    Grant Street Transportation Center
    07:55
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    £55
  • Greyhound US
    13h 35m
    0
    10:50
    Pittsburgh
    Grant Street Transportation Center
    23:25
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    £70

    Cheapest Flights Thursday

  • Spirit Airlines
    17h 23m
    0
    06:10
    Pittsburgh Airport
    Pittsburgh Airport
    22:33
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Spirit Airlines
    Economy
    from £158
  • Allegiant Air
    26h 54m
    0
    17:48
    Pittsburgh Airport
    Pittsburgh Airport
    19:42
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Allegiant Air
    Economy
    from £180
  • Skyscanner
    5h 8m
    0
    06:00
    Pittsburgh Airport
    Pittsburgh Airport
    10:08
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Skyscanner
    Economy
    from £240
  • United Airlines
    6h 52m
    0
    06:35
    Pittsburgh Airport
    Pittsburgh Airport
    12:27
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from £240
  • Alaska Airlines
    29h 5m
    0
    19:54
    Pittsburgh Airport
    Pittsburgh Airport
    23:59
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Alaska Airlines
    Economy
    from £568

    Cheapest Flights Saturday

  • Allegiant Air
    29h 33m
    0
    18:00
    Pittsburgh Airport
    Pittsburgh Airport
    22:33
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Allegiant Air
    Economy
    from £170
  • Spirit Airlines
    27h 56m
    0
    08:00
    Pittsburgh Airport
    Pittsburgh Airport
    10:56
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Spirit Airlines
    Economy
    from £183
  • United Airlines
    6h 52m
    0
    06:35
    Pittsburgh Airport
    Pittsburgh Airport
    12:27
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from £187
  • United Airlines
    4h 58m
    0
    17:45
    Pittsburgh Airport
    Pittsburgh Airport
    21:43
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from £187
  • Skyscanner
    4h 42m
    0
    08:45
    Pittsburgh Airport
    Pittsburgh Airport
    12:27
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Skyscanner
    Economy
    from £187

    Cheapest Buses Sunday

  • Greyhound US
    14h 45m
    0
    01:35
    Pittsburgh
    Grant Street Transportation Center
    15:20
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    £75
  • Greyhound US
    12h 55m
    0
    20:00
    Pittsburgh
    Grant Street Transportation Center
    07:55
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    £75
  • Greyhound US
    13h 35m
    0
    10:50
    Pittsburgh
    Grant Street Transportation Center
    23:25
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    £123

What are the fastest trips from Pittsburgh to St. Louis, MO?

You can get to St. Louis, MO from Pittsburgh in just 4h 42m with a Flight from Skyscanner. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.

Monday
from 5h 50m
Tuesday
from 12h 55m
Wednesday
Thursday
from 5h 8m
Friday
Saturday
from 4h 42m
Sunday
from 12h 55m

    Fastest Flights Monday

  • United Airlines
    5h 50m
    0
    06:00
    Pittsburgh Airport
    Pittsburgh Airport
    10:50
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from £335
  • Skyscanner
    6h 10m
    0
    18:32
    Pittsburgh Airport
    Pittsburgh Airport
    23:42
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Skyscanner
    Economy
    from £335
  • Skyscanner
    7h 42m
    0
    17:00
    Pittsburgh Airport
    Pittsburgh Airport
    23:42
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Skyscanner
    Economy
    from £335
  • Alaska Airlines
    19h 54m
    0
    19:33
    Pittsburgh Airport
    Pittsburgh Airport
    14:27
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Alaska Airlines
    Economy
    from £483
  • Fastest Buses Monday

  • Greyhound US
    12h 55m
    0
    20:00
    Pittsburgh
    Grant Street Transportation Center
    07:55
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    £57
  • Greyhound US
    13h 35m
    0
    10:50
    Pittsburgh
    Grant Street Transportation Center
    23:25
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    £52
  • Greyhound US
    14h 45m
    0
    01:35
    Pittsburgh
    Grant Street Transportation Center
    15:20
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    £52

    Fastest Buses Tuesday

  • Greyhound US
    12h 55m
    0
    20:00
    Pittsburgh
    Grant Street Transportation Center
    07:55
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    £55
  • Greyhound US
    13h 35m
    0
    10:50
    Pittsburgh
    Grant Street Transportation Center
    23:25
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    £70
  • Greyhound US
    14h 45m
    0
    01:35
    Pittsburgh
    Grant Street Transportation Center
    15:20
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    £53

    Fastest Flights Thursday

  • Skyscanner
    5h 8m
    0
    06:00
    Pittsburgh Airport
    Pittsburgh Airport
    10:08
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Skyscanner
    Economy
    from £240
  • United Airlines
    6h 52m
    0
    06:35
    Pittsburgh Airport
    Pittsburgh Airport
    12:27
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from £240
  • Spirit Airlines
    17h 23m
    0
    06:10
    Pittsburgh Airport
    Pittsburgh Airport
    22:33
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Spirit Airlines
    Economy
    from £158
  • Allegiant Air
    26h 54m
    0
    17:48
    Pittsburgh Airport
    Pittsburgh Airport
    19:42
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Allegiant Air
    Economy
    from £180
  • Alaska Airlines
    29h 5m
    0
    19:54
    Pittsburgh Airport
    Pittsburgh Airport
    23:59
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Alaska Airlines
    Economy
    from £568

    Fastest Flights Saturday

  • Skyscanner
    4h 42m
    0
    08:45
    Pittsburgh Airport
    Pittsburgh Airport
    12:27
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Skyscanner
    Economy
    from £187
  • United Airlines
    4h 58m
    0
    17:45
    Pittsburgh Airport
    Pittsburgh Airport
    21:43
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from £187
  • United Airlines
    6h 52m
    0
    06:35
    Pittsburgh Airport
    Pittsburgh Airport
    12:27
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from £187
  • Spirit Airlines
    27h 56m
    0
    08:00
    Pittsburgh Airport
    Pittsburgh Airport
    10:56
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Spirit Airlines
    Economy
    from £183
  • Allegiant Air
    29h 33m
    0
    18:00
    Pittsburgh Airport
    Pittsburgh Airport
    22:33
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Allegiant Air
    Economy
    from £170

    Fastest Buses Sunday

  • Greyhound US
    12h 55m
    0
    20:00
    Pittsburgh
    Grant Street Transportation Center
    07:55
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    £75
  • Greyhound US
    13h 35m
    0
    10:50
    Pittsburgh
    Grant Street Transportation Center
    23:25
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    £123
  • Greyhound US
    14h 45m
    0
    01:35
    Pittsburgh
    Grant Street Transportation Center
    15:20
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    £75
Here you will find all operators and timetables for a Bus from Pittsburgh to St. Louis, MO

What are the most popular stations in Pittsburgh and St. Louis, MO?

In Pittsburgh, you will usually depart from Grant Street Transportation Center, David L. Lawrence Convention Center or Central Station, while in St. Louis, MO you will be arriving at Gateway Station, Lindbergh @ Hackberry NB Bus Stop or Skinker Boulevard, but there are many more stops to explore in both locations.

How do I decide? Some tips and tricks from our experience

Are you having trouble deciding on how to get to St. Louis, MO from Pittsburgh? With 5 connections between 1 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.

Look for the lowest price

Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Pittsburgh and St. Louis, MO, you can pay as low as £52 with a Bus from Greyhound US.

Travel duration

Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Skyscanner: you will get to St. Louis, MO in just 4h 42m.

Comfort makes all the difference

You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Pittsburgh and St. Louis, MO are Greyhound US, United Airlines and Skyscanner, but be sure to check what they have to offer!

Save money with deals, and always compare

One last tip? Even if you live in Pittsburgh and St. Louis, MO is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Green Tree, PA or to Sauget, IL, and look at flights from Pittsburgh Airport, and landing at St. Louis Lambert Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!

Which companies offer a trip from Pittsburgh to St. Louis, MO?

The most popular companies between Pittsburgh and St. Louis, MO, are Greyhound US, United Airlines and Skyscanner. Be sure to check their seat class offers and the amenities that they provide.

Bus companies: Greyhound US

Airlines: United Airlines, Skyscanner, Alaska Airlines and 2 more.

All you need to know when you travel from Pittsburgh to St. Louis, MO

Check all information on comfort and services on all modes of transports from Pittsburgh to St. Louis, MO. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.

FAQs about the trip from Pittsburgh to St. Louis, MO

How can I reach St. Louis, MO from Pittsburgh?

Every day, there are on average 5 connections between Bus and Flight, with which you can get to St. Louis, MO from Pittsburgh.

How far is St. Louis, MO from Pittsburgh?

The distance between Pittsburgh and St. Louis, MO is 898.0 km.

What is the most ecofriendly mode of transport between Pittsburgh and St. Louis, MO?

Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance. On this particular route, a bus will emit, per person, a total of 24 kgs of CO2, a train 31 kgs, a car 153 kgs, and a flight 221 kgs.

What is the cheapest mode of transport from Pittsburgh to St. Louis, MO?

You can get to St. Louis, MO with just £52 by taking a Bus from Greyhound US.

What is the fastest way to get from Pittsburgh to St. Louis, MO?

While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to St. Louis, MO in just 4h 42m with a Flight from Skyscanner.

More routes to Pittsburgh and to St. Louis, MO

Looking for more options? Here you can see the most popular routes to Pittsburgh and to St. Louis, MO. Simply click on a connection, and you’ll find all the details about the route!

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