What is the best way to travel from Middlesbrough to Southampton?
Looking for a trip? Check and compare all the available Flights and Buses to Southampton from Middlesbrough. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
What is the cheapest way to reach Southampton from Middlesbrough?
You can reach Southampton with just £16 by taking a Bus from National Express, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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KLM Cityhopper11h 0m006:00Durham Tees Valley AirportDurham Tees Valley Airport17:00Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 21/03/2026 06:00:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 21/03/2026 17:00:00. 50 Economy ticket for £562 per person are available. Travel duration is 11h 0m
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KLM Cityhopper7h 0m010:00Durham Tees Valley AirportDurham Tees Valley Airport17:00Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 21/03/2026 10:00:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 21/03/2026 17:00:00. 50 Economy ticket for £562 per person are available. Travel duration is 7h 0m
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KLM Cityhopper23h 25m017:50Durham Tees Valley AirportDurham Tees Valley Airport17:15Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 21/03/2026 17:50:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 22/03/2026 17:15:00. 50 Economy ticket for £573 per person are available. Travel duration is 23h 25m
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KLM Cityhopper15h 0m017:50Durham Tees Valley AirportDurham Tees Valley Airport08:50Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 21/03/2026 17:50:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 22/03/2026 08:50:00. 50 Economy ticket for £579 per person are available. Travel duration is 15h 0m
Cheapest Flights Saturday
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National Express9h 15m016:15MiddlesbroughCoach Station01:30SouthamptonCoach Station0EconomyA Bus from National Express goes from Coach Station, Middlesbrough (United Kingdom) at 22/03/2026 16:15:00 to Coach Station, Southampton (United Kingdom) arriving at 23/03/2026 01:30:00. 50 Economy ticket for £32 per person are available. Travel duration is 9h 15m
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National Express10h 20m009:30MiddlesbroughCoach Station19:50SouthamptonCoach Station0EconomyA Bus from National Express goes from Coach Station, Middlesbrough (United Kingdom) at 22/03/2026 09:30:00 to Coach Station, Southampton (United Kingdom) arriving at 22/03/2026 19:50:00. 50 Economy ticket for £33 per person are available. Travel duration is 10h 20m
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National Express10h 40m013:25MiddlesbroughCoach Station00:05SouthamptonCoach Station0EconomyA Bus from National Express goes from Coach Station, Middlesbrough (United Kingdom) at 22/03/2026 13:25:00 to Coach Station, Southampton (United Kingdom) arriving at 23/03/2026 00:05:00. 50 Economy ticket for £34 per person are available. Travel duration is 10h 40m
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National Express10h 35m000:45MiddlesbroughCoach Station11:20SouthamptonCoach Station0EconomyA Bus from National Express goes from Coach Station, Middlesbrough (United Kingdom) at 22/03/2026 00:45:00 to Coach Station, Southampton (United Kingdom) arriving at 22/03/2026 11:20:00. 50 Economy ticket for £41 per person are available. Travel duration is 10h 35m
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National Express10h 0m007:15MiddlesbroughCoach Station17:15SouthamptonCoach Station0EconomyA Bus from National Express goes from Coach Station, Middlesbrough (United Kingdom) at 22/03/2026 07:15:00 to Coach Station, Southampton (United Kingdom) arriving at 22/03/2026 17:15:00. 50 Economy ticket for £45 per person are available. Travel duration is 10h 0m
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KLM Cityhopper26h 20m006:00Durham Tees Valley AirportDurham Tees Valley Airport08:20Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 22/03/2026 06:00:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 23/03/2026 08:20:00. 50 Economy ticket for £282 per person are available. Travel duration is 26h 20m
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KLM Cityhopper14h 50m017:30Durham Tees Valley AirportDurham Tees Valley Airport08:20Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 22/03/2026 17:30:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 23/03/2026 08:20:00. 50 Economy ticket for £282 per person are available. Travel duration is 14h 50m
Cheapest Buses Sunday
Cheapest Flights Sunday
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Ryanair24h 45m018:30Durham Tees Valley AirportDurham Tees Valley Airport19:15Bournemouth AirportBournemouth Airport0EconomyA Flight from Ryanair goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 23/03/2026 18:30:00 to Bournemouth Airport, Bournemouth Airport (United Kingdom) arriving at 24/03/2026 19:15:00. 50 Economy ticket for £55 per person are available. Travel duration is 24h 45m
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KLM Cityhopper23h 30m017:30Durham Tees Valley AirportDurham Tees Valley Airport17:00Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 23/03/2026 17:30:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 24/03/2026 17:00:00. 50 Economy ticket for £345 per person are available. Travel duration is 23h 30m
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KLM Cityhopper14h 50m017:30Durham Tees Valley AirportDurham Tees Valley Airport08:20Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 23/03/2026 17:30:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 24/03/2026 08:20:00. 50 Economy ticket for £347 per person are available. Travel duration is 14h 50m
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KLM Cityhopper26h 20m006:00Durham Tees Valley AirportDurham Tees Valley Airport08:20Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 23/03/2026 06:00:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 24/03/2026 08:20:00. 50 Economy ticket for £460 per person are available. Travel duration is 26h 20m
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KLM Cityhopper22h 20m010:00Durham Tees Valley AirportDurham Tees Valley Airport08:20Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 23/03/2026 10:00:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 24/03/2026 08:20:00. 50 Economy ticket for £720 per person are available. Travel duration is 22h 20m
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KLM Cityhopper11h 5m006:00Durham Tees Valley AirportDurham Tees Valley Airport17:05Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 23/03/2026 06:00:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 23/03/2026 17:05:00. 50 Economy ticket for £723 per person are available. Travel duration is 11h 5m
Cheapest Flights Monday
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KLM Cityhopper14h 35m017:45Durham Tees Valley AirportDurham Tees Valley Airport08:20Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 24/03/2026 17:45:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 25/03/2026 08:20:00. 50 Economy ticket for £394 per person are available. Travel duration is 14h 35m
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KLM Cityhopper11h 0m006:00Durham Tees Valley AirportDurham Tees Valley Airport17:00Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 24/03/2026 06:00:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 24/03/2026 17:00:00. 50 Economy ticket for £448 per person are available. Travel duration is 11h 0m
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KLM Cityhopper7h 0m010:00Durham Tees Valley AirportDurham Tees Valley Airport17:00Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 24/03/2026 10:00:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 24/03/2026 17:00:00. 50 Economy ticket for £562 per person are available. Travel duration is 7h 0m
Cheapest Flights Tuesday
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National Express10h 10m013:25MiddlesbroughCoach Station23:35SouthamptonCoach Station0EconomyA Bus from National Express goes from Coach Station, Middlesbrough (United Kingdom) at 25/03/2026 13:25:00 to Coach Station, Southampton (United Kingdom) arriving at 25/03/2026 23:35:00. 50 Economy ticket for £16 per person are available. Travel duration is 10h 10m
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National Express10h 40m009:30MiddlesbroughCoach Station20:10SouthamptonCoach Station0EconomyA Bus from National Express goes from Coach Station, Middlesbrough (United Kingdom) at 25/03/2026 09:30:00 to Coach Station, Southampton (United Kingdom) arriving at 25/03/2026 20:10:00. 50 Economy ticket for £17 per person are available. Travel duration is 10h 40m
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National Express10h 50m016:10MiddlesbroughCoach Station03:00SouthamptonCoach Station0EconomyA Bus from National Express goes from Coach Station, Middlesbrough (United Kingdom) at 25/03/2026 16:10:00 to Coach Station, Southampton (United Kingdom) arriving at 26/03/2026 03:00:00. 50 Economy ticket for £18 per person are available. Travel duration is 10h 50m
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National Express10h 35m000:45MiddlesbroughCoach Station11:20SouthamptonCoach Station0EconomyA Bus from National Express goes from Coach Station, Middlesbrough (United Kingdom) at 25/03/2026 00:45:00 to Coach Station, Southampton (United Kingdom) arriving at 25/03/2026 11:20:00. 50 Economy ticket for £21 per person are available. Travel duration is 10h 35m
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National Express10h 30m007:00MiddlesbroughCoach Station17:30SouthamptonCoach Station0EconomyA Bus from National Express goes from Coach Station, Middlesbrough (United Kingdom) at 25/03/2026 07:00:00 to Coach Station, Southampton (United Kingdom) arriving at 25/03/2026 17:30:00. 50 Economy ticket for £24 per person are available. Travel duration is 10h 30m
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KLM Cityhopper11h 0m006:00Durham Tees Valley AirportDurham Tees Valley Airport17:00Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 25/03/2026 06:00:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 25/03/2026 17:00:00. 50 Economy ticket for £230 per person are available. Travel duration is 11h 0m
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KLM Cityhopper7h 0m010:00Durham Tees Valley AirportDurham Tees Valley Airport17:00Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 25/03/2026 10:00:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 25/03/2026 17:00:00. 50 Economy ticket for £230 per person are available. Travel duration is 7h 0m
Cheapest Buses Wednesday
Cheapest Flights Wednesday
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KLM Cityhopper26h 20m006:00Durham Tees Valley AirportDurham Tees Valley Airport08:20Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 26/03/2026 06:00:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 27/03/2026 08:20:00. 50 Economy ticket for £281 per person are available. Travel duration is 26h 20m
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KLM Cityhopper7h 25m010:00Durham Tees Valley AirportDurham Tees Valley Airport17:25Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 26/03/2026 10:00:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 26/03/2026 17:25:00. 50 Economy ticket for £338 per person are available. Travel duration is 7h 25m
Cheapest Flights Thursday
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National Express11h 10m008:30MiddlesbroughCoach Station19:40SouthamptonCoach Station0EconomyA Bus from National Express goes from Coach Station, Middlesbrough (United Kingdom) at 27/03/2026 08:30:00 to Coach Station, Southampton (United Kingdom) arriving at 27/03/2026 19:40:00. 50 Economy ticket for £27 per person are available. Travel duration is 11h 10m
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National Express11h 10m009:30MiddlesbroughCoach Station20:40SouthamptonCoach Station0EconomyA Bus from National Express goes from Coach Station, Middlesbrough (United Kingdom) at 27/03/2026 09:30:00 to Coach Station, Southampton (United Kingdom) arriving at 27/03/2026 20:40:00. 50 Economy ticket for £27 per person are available. Travel duration is 11h 10m
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National Express9h 20m016:10MiddlesbroughCoach Station01:30SouthamptonCoach Station0EconomyA Bus from National Express goes from Coach Station, Middlesbrough (United Kingdom) at 27/03/2026 16:10:00 to Coach Station, Southampton (United Kingdom) arriving at 28/03/2026 01:30:00. 50 Economy ticket for £27 per person are available. Travel duration is 9h 20m
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National Express10h 40m013:25MiddlesbroughCoach Station00:05SouthamptonCoach Station0EconomyA Bus from National Express goes from Coach Station, Middlesbrough (United Kingdom) at 27/03/2026 13:25:00 to Coach Station, Southampton (United Kingdom) arriving at 28/03/2026 00:05:00. 50 Economy ticket for £28 per person are available. Travel duration is 10h 40m
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National Express10h 35m000:45MiddlesbroughCoach Station11:20SouthamptonCoach Station0EconomyA Bus from National Express goes from Coach Station, Middlesbrough (United Kingdom) at 27/03/2026 00:45:00 to Coach Station, Southampton (United Kingdom) arriving at 27/03/2026 11:20:00. 50 Economy ticket for £34 per person are available. Travel duration is 10h 35m
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Ryanair27h 55m018:25Durham Tees Valley AirportDurham Tees Valley Airport22:20Bournemouth AirportBournemouth Airport0EconomyA Flight from Ryanair goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 27/03/2026 18:25:00 to Bournemouth Airport, Bournemouth Airport (United Kingdom) arriving at 28/03/2026 22:20:00. 50 Economy ticket for £84 per person are available. Travel duration is 27h 55m
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Ryanair18h 30m018:25Durham Tees Valley AirportDurham Tees Valley Airport12:55Bournemouth AirportBournemouth Airport0EconomyA Flight from Ryanair goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 27/03/2026 18:25:00 to Bournemouth Airport, Bournemouth Airport (United Kingdom) arriving at 28/03/2026 12:55:00. 50 Economy ticket for £97 per person are available. Travel duration is 18h 30m
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KLM Cityhopper22h 50m010:00Durham Tees Valley AirportDurham Tees Valley Airport08:50Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 27/03/2026 10:00:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 28/03/2026 08:50:00. 50 Economy ticket for £258 per person are available. Travel duration is 22h 50m
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KLM Cityhopper15h 5m017:45Durham Tees Valley AirportDurham Tees Valley Airport08:50Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 27/03/2026 17:45:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 28/03/2026 08:50:00. 50 Economy ticket for £258 per person are available. Travel duration is 15h 5m
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KLM Cityhopper11h 0m006:00Durham Tees Valley AirportDurham Tees Valley Airport17:00Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 27/03/2026 06:00:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 27/03/2026 17:00:00. 50 Economy ticket for £305 per person are available. Travel duration is 11h 0m
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KLM Cityhopper7h 0m010:00Durham Tees Valley AirportDurham Tees Valley Airport17:00Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 27/03/2026 10:00:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 27/03/2026 17:00:00. 50 Economy ticket for £305 per person are available. Travel duration is 7h 0m
Cheapest Buses Friday
Cheapest Flights Friday
What are the fastest trips from Middlesbrough to Southampton?
You can get to Southampton from Middlesbrough in just 7h 0m with a Flight from KLM Cityhopper. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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KLM Cityhopper7h 0m010:00Durham Tees Valley AirportDurham Tees Valley Airport17:00Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 21/03/2026 10:00:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 21/03/2026 17:00:00. 50 Economy ticket for £562 per person are available. Travel duration is 7h 0m
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KLM Cityhopper11h 0m006:00Durham Tees Valley AirportDurham Tees Valley Airport17:00Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 21/03/2026 06:00:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 21/03/2026 17:00:00. 50 Economy ticket for £562 per person are available. Travel duration is 11h 0m
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KLM Cityhopper15h 0m017:50Durham Tees Valley AirportDurham Tees Valley Airport08:50Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 21/03/2026 17:50:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 22/03/2026 08:50:00. 50 Economy ticket for £579 per person are available. Travel duration is 15h 0m
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KLM Cityhopper23h 25m017:50Durham Tees Valley AirportDurham Tees Valley Airport17:15Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 21/03/2026 17:50:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 22/03/2026 17:15:00. 50 Economy ticket for £573 per person are available. Travel duration is 23h 25m
Fastest Flights Saturday
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National Express9h 15m016:15MiddlesbroughCoach Station01:30SouthamptonCoach Station0EconomyA Bus from National Express goes from Coach Station, Middlesbrough (United Kingdom) at 22/03/2026 16:15:00 to Coach Station, Southampton (United Kingdom) arriving at 23/03/2026 01:30:00. 50 Economy ticket for £32 per person are available. Travel duration is 9h 15m
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National Express10h 0m007:15MiddlesbroughCoach Station17:15SouthamptonCoach Station0EconomyA Bus from National Express goes from Coach Station, Middlesbrough (United Kingdom) at 22/03/2026 07:15:00 to Coach Station, Southampton (United Kingdom) arriving at 22/03/2026 17:15:00. 50 Economy ticket for £45 per person are available. Travel duration is 10h 0m
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National Express10h 20m009:30MiddlesbroughCoach Station19:50SouthamptonCoach Station0EconomyA Bus from National Express goes from Coach Station, Middlesbrough (United Kingdom) at 22/03/2026 09:30:00 to Coach Station, Southampton (United Kingdom) arriving at 22/03/2026 19:50:00. 50 Economy ticket for £33 per person are available. Travel duration is 10h 20m
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National Express10h 35m000:45MiddlesbroughCoach Station11:20SouthamptonCoach Station0EconomyA Bus from National Express goes from Coach Station, Middlesbrough (United Kingdom) at 22/03/2026 00:45:00 to Coach Station, Southampton (United Kingdom) arriving at 22/03/2026 11:20:00. 50 Economy ticket for £41 per person are available. Travel duration is 10h 35m
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National Express10h 40m013:25MiddlesbroughCoach Station00:05SouthamptonCoach Station0EconomyA Bus from National Express goes from Coach Station, Middlesbrough (United Kingdom) at 22/03/2026 13:25:00 to Coach Station, Southampton (United Kingdom) arriving at 23/03/2026 00:05:00. 50 Economy ticket for £34 per person are available. Travel duration is 10h 40m
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KLM Cityhopper14h 50m017:30Durham Tees Valley AirportDurham Tees Valley Airport08:20Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 22/03/2026 17:30:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 23/03/2026 08:20:00. 50 Economy ticket for £282 per person are available. Travel duration is 14h 50m
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KLM Cityhopper26h 20m006:00Durham Tees Valley AirportDurham Tees Valley Airport08:20Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 22/03/2026 06:00:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 23/03/2026 08:20:00. 50 Economy ticket for £282 per person are available. Travel duration is 26h 20m
Fastest Buses Sunday
Fastest Flights Sunday
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KLM Cityhopper11h 5m006:00Durham Tees Valley AirportDurham Tees Valley Airport17:05Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 23/03/2026 06:00:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 23/03/2026 17:05:00. 50 Economy ticket for £723 per person are available. Travel duration is 11h 5m
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KLM Cityhopper14h 50m017:30Durham Tees Valley AirportDurham Tees Valley Airport08:20Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 23/03/2026 17:30:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 24/03/2026 08:20:00. 50 Economy ticket for £347 per person are available. Travel duration is 14h 50m
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KLM Cityhopper22h 20m010:00Durham Tees Valley AirportDurham Tees Valley Airport08:20Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 23/03/2026 10:00:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 24/03/2026 08:20:00. 50 Economy ticket for £720 per person are available. Travel duration is 22h 20m
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KLM Cityhopper23h 30m017:30Durham Tees Valley AirportDurham Tees Valley Airport17:00Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 23/03/2026 17:30:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 24/03/2026 17:00:00. 50 Economy ticket for £345 per person are available. Travel duration is 23h 30m
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Ryanair24h 45m018:30Durham Tees Valley AirportDurham Tees Valley Airport19:15Bournemouth AirportBournemouth Airport0EconomyA Flight from Ryanair goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 23/03/2026 18:30:00 to Bournemouth Airport, Bournemouth Airport (United Kingdom) arriving at 24/03/2026 19:15:00. 50 Economy ticket for £55 per person are available. Travel duration is 24h 45m
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KLM Cityhopper26h 20m006:00Durham Tees Valley AirportDurham Tees Valley Airport08:20Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 23/03/2026 06:00:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 24/03/2026 08:20:00. 50 Economy ticket for £460 per person are available. Travel duration is 26h 20m
Fastest Flights Monday
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KLM Cityhopper7h 0m010:00Durham Tees Valley AirportDurham Tees Valley Airport17:00Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 24/03/2026 10:00:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 24/03/2026 17:00:00. 50 Economy ticket for £562 per person are available. Travel duration is 7h 0m
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KLM Cityhopper11h 0m006:00Durham Tees Valley AirportDurham Tees Valley Airport17:00Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 24/03/2026 06:00:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 24/03/2026 17:00:00. 50 Economy ticket for £448 per person are available. Travel duration is 11h 0m
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KLM Cityhopper14h 35m017:45Durham Tees Valley AirportDurham Tees Valley Airport08:20Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 24/03/2026 17:45:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 25/03/2026 08:20:00. 50 Economy ticket for £394 per person are available. Travel duration is 14h 35m
Fastest Flights Tuesday
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KLM Cityhopper7h 0m010:00Durham Tees Valley AirportDurham Tees Valley Airport17:00Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 25/03/2026 10:00:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 25/03/2026 17:00:00. 50 Economy ticket for £230 per person are available. Travel duration is 7h 0m
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KLM Cityhopper11h 0m006:00Durham Tees Valley AirportDurham Tees Valley Airport17:00Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 25/03/2026 06:00:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 25/03/2026 17:00:00. 50 Economy ticket for £230 per person are available. Travel duration is 11h 0m
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National Express10h 10m013:25MiddlesbroughCoach Station23:35SouthamptonCoach Station0EconomyA Bus from National Express goes from Coach Station, Middlesbrough (United Kingdom) at 25/03/2026 13:25:00 to Coach Station, Southampton (United Kingdom) arriving at 25/03/2026 23:35:00. 50 Economy ticket for £16 per person are available. Travel duration is 10h 10m
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National Express10h 30m007:00MiddlesbroughCoach Station17:30SouthamptonCoach Station0EconomyA Bus from National Express goes from Coach Station, Middlesbrough (United Kingdom) at 25/03/2026 07:00:00 to Coach Station, Southampton (United Kingdom) arriving at 25/03/2026 17:30:00. 50 Economy ticket for £24 per person are available. Travel duration is 10h 30m
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National Express10h 35m000:45MiddlesbroughCoach Station11:20SouthamptonCoach Station0EconomyA Bus from National Express goes from Coach Station, Middlesbrough (United Kingdom) at 25/03/2026 00:45:00 to Coach Station, Southampton (United Kingdom) arriving at 25/03/2026 11:20:00. 50 Economy ticket for £21 per person are available. Travel duration is 10h 35m
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National Express10h 40m009:30MiddlesbroughCoach Station20:10SouthamptonCoach Station0EconomyA Bus from National Express goes from Coach Station, Middlesbrough (United Kingdom) at 25/03/2026 09:30:00 to Coach Station, Southampton (United Kingdom) arriving at 25/03/2026 20:10:00. 50 Economy ticket for £17 per person are available. Travel duration is 10h 40m
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National Express10h 50m016:10MiddlesbroughCoach Station03:00SouthamptonCoach Station0EconomyA Bus from National Express goes from Coach Station, Middlesbrough (United Kingdom) at 25/03/2026 16:10:00 to Coach Station, Southampton (United Kingdom) arriving at 26/03/2026 03:00:00. 50 Economy ticket for £18 per person are available. Travel duration is 10h 50m
Fastest Flights Wednesday
Fastest Buses Wednesday
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KLM Cityhopper7h 25m010:00Durham Tees Valley AirportDurham Tees Valley Airport17:25Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 26/03/2026 10:00:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 26/03/2026 17:25:00. 50 Economy ticket for £338 per person are available. Travel duration is 7h 25m
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KLM Cityhopper26h 20m006:00Durham Tees Valley AirportDurham Tees Valley Airport08:20Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 26/03/2026 06:00:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 27/03/2026 08:20:00. 50 Economy ticket for £281 per person are available. Travel duration is 26h 20m
Fastest Flights Thursday
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KLM Cityhopper7h 0m010:00Durham Tees Valley AirportDurham Tees Valley Airport17:00Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 27/03/2026 10:00:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 27/03/2026 17:00:00. 50 Economy ticket for £305 per person are available. Travel duration is 7h 0m
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KLM Cityhopper11h 0m006:00Durham Tees Valley AirportDurham Tees Valley Airport17:00Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 27/03/2026 06:00:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 27/03/2026 17:00:00. 50 Economy ticket for £305 per person are available. Travel duration is 11h 0m
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KLM Cityhopper15h 5m017:45Durham Tees Valley AirportDurham Tees Valley Airport08:50Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 27/03/2026 17:45:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 28/03/2026 08:50:00. 50 Economy ticket for £258 per person are available. Travel duration is 15h 5m
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Ryanair18h 30m018:25Durham Tees Valley AirportDurham Tees Valley Airport12:55Bournemouth AirportBournemouth Airport0EconomyA Flight from Ryanair goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 27/03/2026 18:25:00 to Bournemouth Airport, Bournemouth Airport (United Kingdom) arriving at 28/03/2026 12:55:00. 50 Economy ticket for £97 per person are available. Travel duration is 18h 30m
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KLM Cityhopper22h 50m010:00Durham Tees Valley AirportDurham Tees Valley Airport08:50Southampton AirportSouthampton Airport0EconomyA Flight from KLM Cityhopper goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 27/03/2026 10:00:00 to Southampton Airport, Southampton Airport (United Kingdom) arriving at 28/03/2026 08:50:00. 50 Economy ticket for £258 per person are available. Travel duration is 22h 50m
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Ryanair27h 55m018:25Durham Tees Valley AirportDurham Tees Valley Airport22:20Bournemouth AirportBournemouth Airport0EconomyA Flight from Ryanair goes from Durham Tees Valley Airport, Durham Tees Valley Airport (United Kingdom) at 27/03/2026 18:25:00 to Bournemouth Airport, Bournemouth Airport (United Kingdom) arriving at 28/03/2026 22:20:00. 50 Economy ticket for £84 per person are available. Travel duration is 27h 55m
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National Express9h 20m016:10MiddlesbroughCoach Station01:30SouthamptonCoach Station0EconomyA Bus from National Express goes from Coach Station, Middlesbrough (United Kingdom) at 27/03/2026 16:10:00 to Coach Station, Southampton (United Kingdom) arriving at 28/03/2026 01:30:00. 50 Economy ticket for £27 per person are available. Travel duration is 9h 20m
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National Express10h 35m000:45MiddlesbroughCoach Station11:20SouthamptonCoach Station0EconomyA Bus from National Express goes from Coach Station, Middlesbrough (United Kingdom) at 27/03/2026 00:45:00 to Coach Station, Southampton (United Kingdom) arriving at 27/03/2026 11:20:00. 50 Economy ticket for £34 per person are available. Travel duration is 10h 35m
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National Express10h 40m013:25MiddlesbroughCoach Station00:05SouthamptonCoach Station0EconomyA Bus from National Express goes from Coach Station, Middlesbrough (United Kingdom) at 27/03/2026 13:25:00 to Coach Station, Southampton (United Kingdom) arriving at 28/03/2026 00:05:00. 50 Economy ticket for £28 per person are available. Travel duration is 10h 40m
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National Express11h 10m008:30MiddlesbroughCoach Station19:40SouthamptonCoach Station0EconomyA Bus from National Express goes from Coach Station, Middlesbrough (United Kingdom) at 27/03/2026 08:30:00 to Coach Station, Southampton (United Kingdom) arriving at 27/03/2026 19:40:00. 50 Economy ticket for £27 per person are available. Travel duration is 11h 10m
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National Express11h 10m009:30MiddlesbroughCoach Station20:40SouthamptonCoach Station0EconomyA Bus from National Express goes from Coach Station, Middlesbrough (United Kingdom) at 27/03/2026 09:30:00 to Coach Station, Southampton (United Kingdom) arriving at 27/03/2026 20:40:00. 50 Economy ticket for £27 per person are available. Travel duration is 11h 10m
Fastest Flights Friday
Fastest Buses Friday
Here you will find all operators and timetables for a
Bus from Middlesbrough to Southampton
What are the most popular stations in Middlesbrough and Southampton?
In Middlesbrough, you will usually depart from Coach Station, Nunthorpe Train Station or Central Station, while in Southampton you will be arriving at Central Station, Coach Station or Swanwick Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Southampton from Middlesbrough? With 5 connections between 1 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Middlesbrough and Southampton, you can pay as low as £16 with a Bus from National Express.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from KLM Cityhopper: you will get to Southampton in just 7h 0m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Middlesbrough and Southampton are KLM Cityhopper, National Express and Ryanair, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Middlesbrough and Southampton is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Thornaby or to Netley, and look at flights from Durham Tees Valley Airport, and landing at Bournemouth Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Middlesbrough to Southampton?
The most popular companies between Middlesbrough and Southampton, are KLM Cityhopper, National Express and Ryanair. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: National Express
Airlines: KLM Cityhopper and Ryanair
All you need to know when you travel from Middlesbrough to Southampton
Check all information on comfort and services on all modes of transports from Middlesbrough to Southampton. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Middlesbrough to Southampton
How can I reach Southampton from Middlesbrough?
Every day, there are on average 5 connections between Bus and Flight, with which you can get to Southampton from Middlesbrough.
How far is Southampton from Middlesbrough?
The distance between Middlesbrough and Southampton is 407.6 km.
What is the most ecofriendly mode of transport between Middlesbrough and Southampton?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 11 kgs of CO2, a train 14 kgs, a car 69 kgs, and a flight 100 kgs.
What is the cheapest mode of transport from Middlesbrough to Southampton?
You can get to Southampton with just £16 by taking a Bus from National Express.
What is the fastest way to get from Middlesbrough to Southampton?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Southampton in just 7h 0m with a Flight from KLM Cityhopper.
More routes to Middlesbrough and to Southampton
Looking for more options? Here you can see the most popular routes to Middlesbrough and to Southampton. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Middlesbrough
- Aberdeen to Middlesbrough
- Bradford to Middlesbrough
- Edinburgh to Middlesbrough
- Leeds to Middlesbrough
- Leicester to Middlesbrough
- Liverpool to Middlesbrough
- London Heathrow Airport to Middlesbrough
- London to Middlesbrough
- Newcastle upon Tyne to Middlesbrough
- Nottingham to Middlesbrough
- Southampton to Middlesbrough
- Sunderland to Middlesbrough
- York to Middlesbrough
- Trips to Southampton
- Aberdeen to Southampton
- Bath to Southampton
- Birmingham to Southampton
- Bournemouth to Southampton
- Bradford to Southampton
- Bristol to Southampton
- Carlisle to Southampton
- Coventry to Southampton
- Dundee to Southampton
- Edinburgh to Southampton
- Glasgow to Southampton
- Leeds to Southampton
- London Gatwick Airport to Southampton
- London Heathrow Airport to Southampton
- London to Southampton
- Luton to Southampton
- Newcastle upon Tyne to Southampton
- Nottingham to Southampton
- Oxford to Southampton
- Poole to Southampton
- Portsmouth to Southampton
- Sheffield to Southampton
