What is the best way to travel from Mesa, AZ to San Diego?
Looking for a trip? Check and compare all the available Buses and Flights to San Diego from Mesa, AZ. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
What is the cheapest way to reach San Diego from Mesa, AZ?
You can reach San Diego with just £39 by taking a Bus from FlixBus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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FlixBus13h 30m008:00Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport21:30San DiegoSeaport Village0EconomyA Bus from FlixBus goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 14/07/2025 08:00:00 to Seaport Village, San Diego (USA) arriving at 14/07/2025 21:30:00. 50 Economy ticket for £79 per person are available. Travel duration is 13h 30m
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FlixBus10h 10m008:00Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport18:10San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 14/07/2025 08:00:00 to Old Town Transit Center, San Diego (USA) arriving at 14/07/2025 18:10:00. 50 Economy ticket for £79 per person are available. Travel duration is 10h 10m
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Greyhound US13h 5m020:10Mesa, AZGreyhound09:15San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 14/07/2025 20:10:00 to Old Town Transit Center, San Diego (USA) arriving at 15/07/2025 09:15:00. 50 Economy ticket for £105 per person are available. Travel duration is 13h 5m
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Greyhound US13h 20m020:10Mesa, AZGreyhound09:30San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 14/07/2025 20:10:00 to Old Town Transit Center, San Diego (USA) arriving at 15/07/2025 09:30:00. 50 Economy ticket for £105 per person are available. Travel duration is 13h 20m
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Frontier Airlines1h 16m006:30Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport07:46San Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 14/07/2025 06:30:00 to San Diego Airport, San Diego Airport (USA) arriving at 14/07/2025 07:46:00. 50 Economy ticket for £97 per person are available. Travel duration is 1h 16m
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Frontier Airlines1h 12m015:46Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport16:58San Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 14/07/2025 15:46:00 to San Diego Airport, San Diego Airport (USA) arriving at 14/07/2025 16:58:00. 50 Economy ticket for £97 per person are available. Travel duration is 1h 12m
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American Airlines1h 17m007:39Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport08:56San Diego AirportSan Diego Airport0EconomyA Flight from American Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 14/07/2025 07:39:00 to San Diego Airport, San Diego Airport (USA) arriving at 14/07/2025 08:56:00. 50 Economy ticket for £200 per person are available. Travel duration is 1h 17m
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American Airlines1h 14m014:11Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport15:25San Diego AirportSan Diego Airport0EconomyA Flight from American Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 14/07/2025 14:11:00 to San Diego Airport, San Diego Airport (USA) arriving at 14/07/2025 15:25:00. 50 Economy ticket for £200 per person are available. Travel duration is 1h 14m
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Allegiant Air9h 42m008:28Phoenix-Mesa Gateway AirportBus Stop18:10San Diego AirportSan Diego Airport0EconomyA Flight from Allegiant Air goes from Bus Stop, Phoenix-Mesa Gateway Airport (USA) at 14/07/2025 08:28:00 to San Diego Airport, San Diego Airport (USA) arriving at 14/07/2025 18:10:00. 50 Economy ticket for £210 per person are available. Travel duration is 9h 42m
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Volaris9h 33m009:32Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport19:05Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 14/07/2025 09:32:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 14/07/2025 19:05:00. 50 Economy ticket for £351 per person are available. Travel duration is 9h 33m
Cheapest Buses Monday
Cheapest Flights Monday
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FlixBus10h 10m008:00Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport18:10San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 15/07/2025 08:00:00 to Old Town Transit Center, San Diego (USA) arriving at 15/07/2025 18:10:00. 50 Economy ticket for £49 per person are available. Travel duration is 10h 10m
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FlixBus13h 30m008:00Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport21:30San DiegoSeaport Village0EconomyA Bus from FlixBus goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 15/07/2025 08:00:00 to Seaport Village, San Diego (USA) arriving at 15/07/2025 21:30:00. 50 Economy ticket for £50 per person are available. Travel duration is 13h 30m
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Greyhound US12h 35m020:10Mesa, AZGreyhound08:45San DiegoLa Jolla Village0EconomyA Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 15/07/2025 20:10:00 to La Jolla Village, San Diego (USA) arriving at 16/07/2025 08:45:00. 50 Economy ticket for £52 per person are available. Travel duration is 12h 35m
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Greyhound US13h 5m020:10Mesa, AZGreyhound09:15San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 15/07/2025 20:10:00 to Old Town Transit Center, San Diego (USA) arriving at 16/07/2025 09:15:00. 50 Economy ticket for £53 per person are available. Travel duration is 13h 5m
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Desert bus Lines7h 10m013:00Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport20:10San DiegoOld Town Transit Center0Premium EconomyA Bus from Desert bus Lines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 15/07/2025 13:00:00 to Old Town Transit Center, San Diego (USA) arriving at 15/07/2025 20:10:00. 50 Premium Economy ticket for £100 per person are available. Travel duration is 7h 10m
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Volaris15h 19m009:32Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport00:51Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 15/07/2025 09:32:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 16/07/2025 00:51:00. 50 Economy ticket for £183 per person are available. Travel duration is 15h 19m
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Volaris9h 33m009:32Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport19:05Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 15/07/2025 09:32:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 15/07/2025 19:05:00. 50 Economy ticket for £228 per person are available. Travel duration is 9h 33m
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Aeroméxico10h 15m013:10Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport23:25Tijuana AirportTijuana Airport0EconomyA Flight from Aeroméxico goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 15/07/2025 13:10:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 15/07/2025 23:25:00. 50 Economy ticket for £233 per person are available. Travel duration is 10h 15m
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Aeroméxico9h 26m013:10Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport22:36Tijuana AirportTijuana Airport0EconomyA Flight from Aeroméxico goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 15/07/2025 13:10:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 15/07/2025 22:36:00. 50 Economy ticket for £275 per person are available. Travel duration is 9h 26m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
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Greyhound US13h 55m020:10Mesa, AZGreyhound10:05San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 16/07/2025 20:10:00 to San Ysidro Transit Center, San Diego (USA) arriving at 17/07/2025 10:05:00. 50 Economy ticket for £59 per person are available. Travel duration is 13h 55m
Cheapest Buses Wednesday
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FlixBus13h 30m008:00Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport21:30San DiegoSeaport Village0EconomyA Bus from FlixBus goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 17/07/2025 08:00:00 to Seaport Village, San Diego (USA) arriving at 17/07/2025 21:30:00. 50 Economy ticket for £39 per person are available. Travel duration is 13h 30m
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FlixBus13h 10m012:40Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport01:50San DiegoSeaport Village0EconomyA Bus from FlixBus goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 17/07/2025 12:40:00 to Seaport Village, San Diego (USA) arriving at 18/07/2025 01:50:00. 50 Economy ticket for £39 per person are available. Travel duration is 13h 10m
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FlixBus10h 10m008:00Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport18:10San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 17/07/2025 08:00:00 to Old Town Transit Center, San Diego (USA) arriving at 17/07/2025 18:10:00. 50 Economy ticket for £39 per person are available. Travel duration is 10h 10m
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FlixBus15h 50m008:00Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport23:50San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 17/07/2025 08:00:00 to Old Town Transit Center, San Diego (USA) arriving at 17/07/2025 23:50:00. 50 Economy ticket for £39 per person are available. Travel duration is 15h 50m
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Frontier Airlines1h 13m013:00Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport14:13San Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 17/07/2025 13:00:00 to San Diego Airport, San Diego Airport (USA) arriving at 17/07/2025 14:13:00. 50 Economy ticket for £93 per person are available. Travel duration is 1h 13m
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Frontier Airlines1h 12m015:46Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport16:58San Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 17/07/2025 15:46:00 to San Diego Airport, San Diego Airport (USA) arriving at 17/07/2025 16:58:00. 50 Economy ticket for £93 per person are available. Travel duration is 1h 12m
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American Airlines1h 17m007:39Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport08:56San Diego AirportSan Diego Airport0EconomyA Flight from American Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 17/07/2025 07:39:00 to San Diego Airport, San Diego Airport (USA) arriving at 17/07/2025 08:56:00. 50 Economy ticket for £153 per person are available. Travel duration is 1h 17m
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American Airlines1h 12m010:36Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport11:48San Diego AirportSan Diego Airport0EconomyA Flight from American Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 17/07/2025 10:36:00 to San Diego Airport, San Diego Airport (USA) arriving at 17/07/2025 11:48:00. 50 Economy ticket for £153 per person are available. Travel duration is 1h 12m
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American Airlines1h 14m014:11Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport15:25San Diego AirportSan Diego Airport0EconomyA Flight from American Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 17/07/2025 14:11:00 to San Diego Airport, San Diego Airport (USA) arriving at 17/07/2025 15:25:00. 50 Economy ticket for £153 per person are available. Travel duration is 1h 14m
Cheapest Buses Thursday
Cheapest Flights Thursday
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Greyhound US13h 55m020:10Mesa, AZGreyhound10:05San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 18/07/2025 20:10:00 to San Ysidro Transit Center, San Diego (USA) arriving at 19/07/2025 10:05:00. 50 Economy ticket for £54 per person are available. Travel duration is 13h 55m
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Greyhound US14h 30m020:10Mesa, AZGreyhound10:40San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 18/07/2025 20:10:00 to Seaport Village, San Diego (USA) arriving at 19/07/2025 10:40:00. 50 Economy ticket for £56 per person are available. Travel duration is 14h 30m
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Greyhound US13h 5m020:10Mesa, AZGreyhound09:15San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 18/07/2025 20:10:00 to Old Town Transit Center, San Diego (USA) arriving at 19/07/2025 09:15:00. 50 Economy ticket for £56 per person are available. Travel duration is 13h 5m
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Greyhound US13h 20m020:10Mesa, AZGreyhound09:30San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 18/07/2025 20:10:00 to Old Town Transit Center, San Diego (USA) arriving at 19/07/2025 09:30:00. 50 Economy ticket for £56 per person are available. Travel duration is 13h 20m
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Greyhound US19h 30m020:10Mesa, AZGreyhound15:40San DiegoSDSU Transit Center0EconomyA Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 18/07/2025 20:10:00 to SDSU Transit Center, San Diego (USA) arriving at 19/07/2025 15:40:00. 50 Economy ticket for £56 per person are available. Travel duration is 19h 30m
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Frontier Airlines1h 16m006:30Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport07:46San Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 18/07/2025 06:30:00 to San Diego Airport, San Diego Airport (USA) arriving at 18/07/2025 07:46:00. 50 Economy ticket for £98 per person are available. Travel duration is 1h 16m
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Frontier Airlines1h 12m015:46Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport16:58San Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 18/07/2025 15:46:00 to San Diego Airport, San Diego Airport (USA) arriving at 18/07/2025 16:58:00. 50 Economy ticket for £98 per person are available. Travel duration is 1h 12m
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American Airlines1h 17m007:39Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport08:56San Diego AirportSan Diego Airport0EconomyA Flight from American Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 18/07/2025 07:39:00 to San Diego Airport, San Diego Airport (USA) arriving at 18/07/2025 08:56:00. 50 Economy ticket for £153 per person are available. Travel duration is 1h 17m
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American Airlines1h 12m010:36Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport11:48San Diego AirportSan Diego Airport0EconomyA Flight from American Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 18/07/2025 10:36:00 to San Diego Airport, San Diego Airport (USA) arriving at 18/07/2025 11:48:00. 50 Economy ticket for £153 per person are available. Travel duration is 1h 12m
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American Airlines1h 14m014:11Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport15:25San Diego AirportSan Diego Airport0EconomyA Flight from American Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 18/07/2025 14:11:00 to San Diego Airport, San Diego Airport (USA) arriving at 18/07/2025 15:25:00. 50 Economy ticket for £153 per person are available. Travel duration is 1h 14m
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Volaris8h 32m009:32Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport18:04Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 18/07/2025 09:32:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 18/07/2025 18:04:00. 50 Economy ticket for £381 per person are available. Travel duration is 8h 32m
Cheapest Buses Friday
Cheapest Flights Friday
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FlixBus13h 30m008:00Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport21:30San DiegoSeaport Village0EconomyA Bus from FlixBus goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 19/07/2025 08:00:00 to Seaport Village, San Diego (USA) arriving at 19/07/2025 21:30:00. 50 Economy ticket for £56 per person are available. Travel duration is 13h 30m
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FlixBus10h 10m008:00Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport18:10San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 19/07/2025 08:00:00 to Old Town Transit Center, San Diego (USA) arriving at 19/07/2025 18:10:00. 50 Economy ticket for £57 per person are available. Travel duration is 10h 10m
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Volaris15h 19m009:32Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport00:51Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 19/07/2025 09:32:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 20/07/2025 00:51:00. 50 Economy ticket for £202 per person are available. Travel duration is 15h 19m
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Volaris11h 44m009:32Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport21:16Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 19/07/2025 09:32:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 19/07/2025 21:16:00. 50 Economy ticket for £210 per person are available. Travel duration is 11h 44m
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Volaris8h 32m009:32Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport18:04Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 19/07/2025 09:32:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 19/07/2025 18:04:00. 50 Economy ticket for £236 per person are available. Travel duration is 8h 32m
Cheapest Buses Saturday
Cheapest Flights Saturday
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Greyhound US14h 30m020:10Mesa, AZGreyhound10:40San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 20/07/2025 20:10:00 to Seaport Village, San Diego (USA) arriving at 21/07/2025 10:40:00. 50 Economy ticket for £55 per person are available. Travel duration is 14h 30m
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Greyhound US13h 20m020:10Mesa, AZGreyhound09:30San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 20/07/2025 20:10:00 to Old Town Transit Center, San Diego (USA) arriving at 21/07/2025 09:30:00. 50 Economy ticket for £55 per person are available. Travel duration is 13h 20m
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Greyhound US12h 35m020:10Mesa, AZGreyhound08:45San DiegoLa Jolla Village0EconomyA Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 20/07/2025 20:10:00 to La Jolla Village, San Diego (USA) arriving at 21/07/2025 08:45:00. 50 Economy ticket for £55 per person are available. Travel duration is 12h 35m
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FlixBus10h 10m008:00Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport18:10San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 20/07/2025 08:00:00 to Old Town Transit Center, San Diego (USA) arriving at 20/07/2025 18:10:00. 50 Economy ticket for £58 per person are available. Travel duration is 10h 10m
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FlixBus13h 30m008:00Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport21:30San DiegoSeaport Village0EconomyA Bus from FlixBus goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 20/07/2025 08:00:00 to Seaport Village, San Diego (USA) arriving at 20/07/2025 21:30:00. 50 Economy ticket for £59 per person are available. Travel duration is 13h 30m
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Frontier Airlines1h 16m006:30Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport07:46San Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 20/07/2025 06:30:00 to San Diego Airport, San Diego Airport (USA) arriving at 20/07/2025 07:46:00. 50 Economy ticket for £99 per person are available. Travel duration is 1h 16m
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Frontier Airlines1h 12m015:46Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport16:58San Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 20/07/2025 15:46:00 to San Diego Airport, San Diego Airport (USA) arriving at 20/07/2025 16:58:00. 50 Economy ticket for £99 per person are available. Travel duration is 1h 12m
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American Airlines1h 17m007:39Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport08:56San Diego AirportSan Diego Airport0EconomyA Flight from American Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 20/07/2025 07:39:00 to San Diego Airport, San Diego Airport (USA) arriving at 20/07/2025 08:56:00. 50 Economy ticket for £153 per person are available. Travel duration is 1h 17m
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American Airlines1h 14m014:11Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport15:25San Diego AirportSan Diego Airport0EconomyA Flight from American Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 20/07/2025 14:11:00 to San Diego Airport, San Diego Airport (USA) arriving at 20/07/2025 15:25:00. 50 Economy ticket for £153 per person are available. Travel duration is 1h 14m
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American Airlines1h 10m018:08Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport19:18San Diego AirportSan Diego Airport0EconomyA Flight from American Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 20/07/2025 18:08:00 to San Diego Airport, San Diego Airport (USA) arriving at 20/07/2025 19:18:00. 50 Economy ticket for £153 per person are available. Travel duration is 1h 10m
Cheapest Buses Sunday
Cheapest Flights Sunday
What are the fastest trips from Mesa, AZ to San Diego?
You can get to San Diego from Mesa, AZ in just 1h 10m with a Flight from American Airlines. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Frontier Airlines1h 12m015:46Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport16:58San Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 14/07/2025 15:46:00 to San Diego Airport, San Diego Airport (USA) arriving at 14/07/2025 16:58:00. 50 Economy ticket for £97 per person are available. Travel duration is 1h 12m
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American Airlines1h 14m014:11Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport15:25San Diego AirportSan Diego Airport0EconomyA Flight from American Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 14/07/2025 14:11:00 to San Diego Airport, San Diego Airport (USA) arriving at 14/07/2025 15:25:00. 50 Economy ticket for £200 per person are available. Travel duration is 1h 14m
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Frontier Airlines1h 16m006:30Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport07:46San Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 14/07/2025 06:30:00 to San Diego Airport, San Diego Airport (USA) arriving at 14/07/2025 07:46:00. 50 Economy ticket for £97 per person are available. Travel duration is 1h 16m
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American Airlines1h 17m007:39Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport08:56San Diego AirportSan Diego Airport0EconomyA Flight from American Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 14/07/2025 07:39:00 to San Diego Airport, San Diego Airport (USA) arriving at 14/07/2025 08:56:00. 50 Economy ticket for £200 per person are available. Travel duration is 1h 17m
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Volaris8h 32m009:32Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport18:04Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 14/07/2025 09:32:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 14/07/2025 18:04:00. 50 Economy ticket for £354 per person are available. Travel duration is 8h 32m
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Volaris9h 33m009:32Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport19:05Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 14/07/2025 09:32:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 14/07/2025 19:05:00. 50 Economy ticket for £351 per person are available. Travel duration is 9h 33m
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FlixBus10h 10m008:00Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport18:10San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 14/07/2025 08:00:00 to Old Town Transit Center, San Diego (USA) arriving at 14/07/2025 18:10:00. 50 Economy ticket for £79 per person are available. Travel duration is 10h 10m
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Greyhound US13h 5m020:10Mesa, AZGreyhound09:15San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 14/07/2025 20:10:00 to Old Town Transit Center, San Diego (USA) arriving at 15/07/2025 09:15:00. 50 Economy ticket for £105 per person are available. Travel duration is 13h 5m
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Greyhound US13h 20m020:10Mesa, AZGreyhound09:30San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 14/07/2025 20:10:00 to Old Town Transit Center, San Diego (USA) arriving at 15/07/2025 09:30:00. 50 Economy ticket for £105 per person are available. Travel duration is 13h 20m
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FlixBus13h 30m008:00Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport21:30San DiegoSeaport Village0EconomyA Bus from FlixBus goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 14/07/2025 08:00:00 to Seaport Village, San Diego (USA) arriving at 14/07/2025 21:30:00. 50 Economy ticket for £79 per person are available. Travel duration is 13h 30m
Fastest Flights Monday
Fastest Buses Monday
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Desert bus Lines7h 10m013:00Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport20:10San DiegoOld Town Transit Center0Premium EconomyA Bus from Desert bus Lines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 15/07/2025 13:00:00 to Old Town Transit Center, San Diego (USA) arriving at 15/07/2025 20:10:00. 50 Premium Economy ticket for £100 per person are available. Travel duration is 7h 10m
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FlixBus10h 10m008:00Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport18:10San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 15/07/2025 08:00:00 to Old Town Transit Center, San Diego (USA) arriving at 15/07/2025 18:10:00. 50 Economy ticket for £49 per person are available. Travel duration is 10h 10m
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Greyhound US12h 35m020:10Mesa, AZGreyhound08:45San DiegoLa Jolla Village0EconomyA Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 15/07/2025 20:10:00 to La Jolla Village, San Diego (USA) arriving at 16/07/2025 08:45:00. 50 Economy ticket for £52 per person are available. Travel duration is 12h 35m
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Greyhound US13h 5m020:10Mesa, AZGreyhound09:15San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 15/07/2025 20:10:00 to Old Town Transit Center, San Diego (USA) arriving at 16/07/2025 09:15:00. 50 Economy ticket for £53 per person are available. Travel duration is 13h 5m
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FlixBus13h 30m008:00Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport21:30San DiegoSeaport Village0EconomyA Bus from FlixBus goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 15/07/2025 08:00:00 to Seaport Village, San Diego (USA) arriving at 15/07/2025 21:30:00. 50 Economy ticket for £50 per person are available. Travel duration is 13h 30m
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Aeroméxico9h 26m013:10Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport22:36Tijuana AirportTijuana Airport0EconomyA Flight from Aeroméxico goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 15/07/2025 13:10:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 15/07/2025 22:36:00. 50 Economy ticket for £275 per person are available. Travel duration is 9h 26m
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Volaris9h 33m009:32Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport19:05Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 15/07/2025 09:32:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 15/07/2025 19:05:00. 50 Economy ticket for £228 per person are available. Travel duration is 9h 33m
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Aeroméxico10h 15m013:10Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport23:25Tijuana AirportTijuana Airport0EconomyA Flight from Aeroméxico goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 15/07/2025 13:10:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 15/07/2025 23:25:00. 50 Economy ticket for £233 per person are available. Travel duration is 10h 15m
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Volaris15h 19m009:32Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport00:51Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 15/07/2025 09:32:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 16/07/2025 00:51:00. 50 Economy ticket for £183 per person are available. Travel duration is 15h 19m
Fastest Buses Tuesday
Fastest Flights Tuesday
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Greyhound US13h 55m020:10Mesa, AZGreyhound10:05San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 16/07/2025 20:10:00 to San Ysidro Transit Center, San Diego (USA) arriving at 17/07/2025 10:05:00. 50 Economy ticket for £59 per person are available. Travel duration is 13h 55m
Fastest Buses Wednesday
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Frontier Airlines1h 12m015:46Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport16:58San Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 17/07/2025 15:46:00 to San Diego Airport, San Diego Airport (USA) arriving at 17/07/2025 16:58:00. 50 Economy ticket for £93 per person are available. Travel duration is 1h 12m
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American Airlines1h 12m010:36Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport11:48San Diego AirportSan Diego Airport0EconomyA Flight from American Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 17/07/2025 10:36:00 to San Diego Airport, San Diego Airport (USA) arriving at 17/07/2025 11:48:00. 50 Economy ticket for £153 per person are available. Travel duration is 1h 12m
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Frontier Airlines1h 13m013:00Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport14:13San Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 17/07/2025 13:00:00 to San Diego Airport, San Diego Airport (USA) arriving at 17/07/2025 14:13:00. 50 Economy ticket for £93 per person are available. Travel duration is 1h 13m
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American Airlines1h 14m014:11Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport15:25San Diego AirportSan Diego Airport0EconomyA Flight from American Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 17/07/2025 14:11:00 to San Diego Airport, San Diego Airport (USA) arriving at 17/07/2025 15:25:00. 50 Economy ticket for £153 per person are available. Travel duration is 1h 14m
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American Airlines1h 17m007:39Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport08:56San Diego AirportSan Diego Airport0EconomyA Flight from American Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 17/07/2025 07:39:00 to San Diego Airport, San Diego Airport (USA) arriving at 17/07/2025 08:56:00. 50 Economy ticket for £153 per person are available. Travel duration is 1h 17m
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FlixBus10h 10m008:00Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport18:10San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 17/07/2025 08:00:00 to Old Town Transit Center, San Diego (USA) arriving at 17/07/2025 18:10:00. 50 Economy ticket for £39 per person are available. Travel duration is 10h 10m
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FlixBus13h 10m012:40Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport01:50San DiegoSeaport Village0EconomyA Bus from FlixBus goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 17/07/2025 12:40:00 to Seaport Village, San Diego (USA) arriving at 18/07/2025 01:50:00. 50 Economy ticket for £39 per person are available. Travel duration is 13h 10m
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FlixBus13h 30m008:00Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport21:30San DiegoSeaport Village0EconomyA Bus from FlixBus goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 17/07/2025 08:00:00 to Seaport Village, San Diego (USA) arriving at 17/07/2025 21:30:00. 50 Economy ticket for £39 per person are available. Travel duration is 13h 30m
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FlixBus15h 50m008:00Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport23:50San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 17/07/2025 08:00:00 to Old Town Transit Center, San Diego (USA) arriving at 17/07/2025 23:50:00. 50 Economy ticket for £39 per person are available. Travel duration is 15h 50m
Fastest Flights Thursday
Fastest Buses Thursday
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Frontier Airlines1h 12m015:46Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport16:58San Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 18/07/2025 15:46:00 to San Diego Airport, San Diego Airport (USA) arriving at 18/07/2025 16:58:00. 50 Economy ticket for £98 per person are available. Travel duration is 1h 12m
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American Airlines1h 12m010:36Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport11:48San Diego AirportSan Diego Airport0EconomyA Flight from American Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 18/07/2025 10:36:00 to San Diego Airport, San Diego Airport (USA) arriving at 18/07/2025 11:48:00. 50 Economy ticket for £153 per person are available. Travel duration is 1h 12m
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American Airlines1h 14m014:11Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport15:25San Diego AirportSan Diego Airport0EconomyA Flight from American Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 18/07/2025 14:11:00 to San Diego Airport, San Diego Airport (USA) arriving at 18/07/2025 15:25:00. 50 Economy ticket for £153 per person are available. Travel duration is 1h 14m
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Frontier Airlines1h 16m006:30Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport07:46San Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 18/07/2025 06:30:00 to San Diego Airport, San Diego Airport (USA) arriving at 18/07/2025 07:46:00. 50 Economy ticket for £98 per person are available. Travel duration is 1h 16m
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American Airlines1h 17m007:39Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport08:56San Diego AirportSan Diego Airport0EconomyA Flight from American Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 18/07/2025 07:39:00 to San Diego Airport, San Diego Airport (USA) arriving at 18/07/2025 08:56:00. 50 Economy ticket for £153 per person are available. Travel duration is 1h 17m
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Volaris8h 32m009:32Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport18:04Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 18/07/2025 09:32:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 18/07/2025 18:04:00. 50 Economy ticket for £381 per person are available. Travel duration is 8h 32m
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Greyhound US13h 5m020:10Mesa, AZGreyhound09:15San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 18/07/2025 20:10:00 to Old Town Transit Center, San Diego (USA) arriving at 19/07/2025 09:15:00. 50 Economy ticket for £56 per person are available. Travel duration is 13h 5m
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Greyhound US13h 20m020:10Mesa, AZGreyhound09:30San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 18/07/2025 20:10:00 to Old Town Transit Center, San Diego (USA) arriving at 19/07/2025 09:30:00. 50 Economy ticket for £56 per person are available. Travel duration is 13h 20m
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Greyhound US13h 55m020:10Mesa, AZGreyhound10:05San DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 18/07/2025 20:10:00 to San Ysidro Transit Center, San Diego (USA) arriving at 19/07/2025 10:05:00. 50 Economy ticket for £54 per person are available. Travel duration is 13h 55m
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Greyhound US14h 30m020:10Mesa, AZGreyhound10:40San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 18/07/2025 20:10:00 to Seaport Village, San Diego (USA) arriving at 19/07/2025 10:40:00. 50 Economy ticket for £56 per person are available. Travel duration is 14h 30m
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Greyhound US19h 30m020:10Mesa, AZGreyhound15:40San DiegoSDSU Transit Center0EconomyA Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 18/07/2025 20:10:00 to SDSU Transit Center, San Diego (USA) arriving at 19/07/2025 15:40:00. 50 Economy ticket for £56 per person are available. Travel duration is 19h 30m
Fastest Flights Friday
Fastest Buses Friday
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Volaris8h 32m009:32Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport18:04Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 19/07/2025 09:32:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 19/07/2025 18:04:00. 50 Economy ticket for £236 per person are available. Travel duration is 8h 32m
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Volaris11h 44m009:32Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport21:16Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 19/07/2025 09:32:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 19/07/2025 21:16:00. 50 Economy ticket for £210 per person are available. Travel duration is 11h 44m
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Volaris15h 19m009:32Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport00:51Tijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 19/07/2025 09:32:00 to Tijuana Airport, Tijuana Airport (Mexico) arriving at 20/07/2025 00:51:00. 50 Economy ticket for £202 per person are available. Travel duration is 15h 19m
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FlixBus10h 10m008:00Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport18:10San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 19/07/2025 08:00:00 to Old Town Transit Center, San Diego (USA) arriving at 19/07/2025 18:10:00. 50 Economy ticket for £57 per person are available. Travel duration is 10h 10m
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FlixBus13h 30m008:00Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport21:30San DiegoSeaport Village0EconomyA Bus from FlixBus goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 19/07/2025 08:00:00 to Seaport Village, San Diego (USA) arriving at 19/07/2025 21:30:00. 50 Economy ticket for £56 per person are available. Travel duration is 13h 30m
Fastest Flights Saturday
Fastest Buses Saturday
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American Airlines1h 10m018:08Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport19:18San Diego AirportSan Diego Airport0EconomyA Flight from American Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 20/07/2025 18:08:00 to San Diego Airport, San Diego Airport (USA) arriving at 20/07/2025 19:18:00. 50 Economy ticket for £153 per person are available. Travel duration is 1h 10m
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Frontier Airlines1h 12m015:46Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport16:58San Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 20/07/2025 15:46:00 to San Diego Airport, San Diego Airport (USA) arriving at 20/07/2025 16:58:00. 50 Economy ticket for £99 per person are available. Travel duration is 1h 12m
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American Airlines1h 14m014:11Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport15:25San Diego AirportSan Diego Airport0EconomyA Flight from American Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 20/07/2025 14:11:00 to San Diego Airport, San Diego Airport (USA) arriving at 20/07/2025 15:25:00. 50 Economy ticket for £153 per person are available. Travel duration is 1h 14m
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Frontier Airlines1h 16m006:30Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport07:46San Diego AirportSan Diego Airport0EconomyA Flight from Frontier Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 20/07/2025 06:30:00 to San Diego Airport, San Diego Airport (USA) arriving at 20/07/2025 07:46:00. 50 Economy ticket for £99 per person are available. Travel duration is 1h 16m
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American Airlines1h 17m007:39Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport08:56San Diego AirportSan Diego Airport0EconomyA Flight from American Airlines goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 20/07/2025 07:39:00 to San Diego Airport, San Diego Airport (USA) arriving at 20/07/2025 08:56:00. 50 Economy ticket for £153 per person are available. Travel duration is 1h 17m
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FlixBus10h 10m008:00Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport18:10San DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 20/07/2025 08:00:00 to Old Town Transit Center, San Diego (USA) arriving at 20/07/2025 18:10:00. 50 Economy ticket for £58 per person are available. Travel duration is 10h 10m
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Greyhound US12h 35m020:10Mesa, AZGreyhound08:45San DiegoLa Jolla Village0EconomyA Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 20/07/2025 20:10:00 to La Jolla Village, San Diego (USA) arriving at 21/07/2025 08:45:00. 50 Economy ticket for £55 per person are available. Travel duration is 12h 35m
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Greyhound US13h 20m020:10Mesa, AZGreyhound09:30San DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 20/07/2025 20:10:00 to Old Town Transit Center, San Diego (USA) arriving at 21/07/2025 09:30:00. 50 Economy ticket for £55 per person are available. Travel duration is 13h 20m
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FlixBus13h 30m008:00Phoenix Sky Harbor AirportPhoenix Sky Harbor Airport21:30San DiegoSeaport Village0EconomyA Bus from FlixBus goes from Phoenix Sky Harbor Airport, Phoenix Sky Harbor Airport (USA) at 20/07/2025 08:00:00 to Seaport Village, San Diego (USA) arriving at 20/07/2025 21:30:00. 50 Economy ticket for £59 per person are available. Travel duration is 13h 30m
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Greyhound US14h 30m020:10Mesa, AZGreyhound10:40San DiegoSeaport Village0EconomyA Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 20/07/2025 20:10:00 to Seaport Village, San Diego (USA) arriving at 21/07/2025 10:40:00. 50 Economy ticket for £55 per person are available. Travel duration is 14h 30m
Fastest Flights Sunday
Fastest Buses Sunday
Here you will find all operators and timetables for a
Bus from Mesa, AZ to San Diego
What are the most popular stations in Mesa, AZ and San Diego?
In Mesa, AZ, you will usually depart from Greyhound or Fry’s Fuel Center, while in San Diego you will be arriving at Santa Fe Depot, San Ysidro Transit Center or Old Town Transit Center, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to San Diego from Mesa, AZ? With 8 connections between 1 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Mesa, AZ and San Diego, you can pay as low as £39 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from American Airlines: you will get to San Diego in just 1h 10m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Mesa, AZ and San Diego are Greyhound US, FlixBus and American Airlines, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Mesa, AZ and San Diego is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Tempe, AZ or to San Diego Airport, and look at flights from Phoenix Sky Harbor Airport, and landing at Tijuana Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Mesa, AZ to San Diego?
The most popular companies between Mesa, AZ and San Diego, are Greyhound US, FlixBus and American Airlines. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Greyhound US, FlixBus and Desert bus Lines
Airlines: American Airlines, Volaris, Frontier Airlines and 2 more.
All you need to know when you travel from Mesa, AZ to San Diego
Check all information on comfort and services on all modes of transports from Mesa, AZ to San Diego. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Mesa, AZ to San Diego
How can I reach San Diego from Mesa, AZ?
Every day, there are on average 8 connections between Bus and Flight, with which you can get to San Diego from Mesa, AZ.
How far is San Diego from Mesa, AZ?
The distance between Mesa, AZ and San Diego is 501.6 km.
What is the most ecofriendly mode of transport between Mesa, AZ and San Diego?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 14 kgs of CO2, a train 18 kgs, a car 85 kgs, and a flight 123 kgs.
What is the cheapest mode of transport from Mesa, AZ to San Diego?
You can get to San Diego with just £39 by taking a Bus from FlixBus.
What is the fastest way to get from Mesa, AZ to San Diego?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to San Diego in just 1h 10m with a Flight from American Airlines.
More routes to Mesa, AZ and to San Diego
Looking for more options? Here you can see the most popular routes to Mesa, AZ and to San Diego. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Mesa, AZ
- San Diego to Mesa, AZ