What is the best way to travel from Karlsruhe to Prague?
Looking for a trip? Check and compare all the available Buses, Flights and Carpool to Prague from Karlsruhe. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
What is the cheapest way to reach Prague from Karlsruhe?
You can reach Prague with just £45 by taking a Bus from FlixBus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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FlixBus8h 55m008:35KarlsruheCentral Station17:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 18/12/2025 08:35:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 18/12/2025 17:30:00. 50 Economy ticket for £46 per person are available. Travel duration is 8h 55m
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FlixBus9h 10m008:35KarlsruheCentral Station17:45PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 18/12/2025 08:35:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 18/12/2025 17:45:00. 50 Economy ticket for £46 per person are available. Travel duration is 9h 10m
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FlixBus10h 25m004:55KarlsruheCentral Station15:20PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 18/12/2025 04:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 18/12/2025 15:20:00. 50 Economy ticket for £48 per person are available. Travel duration is 10h 25m
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FlixBus11h 0m016:15KarlsruheCentral Station03:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 18/12/2025 16:15:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 19/12/2025 03:15:00. 50 Economy ticket for £48 per person are available. Travel duration is 11h 0m
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Lauda Europe15h 30m008:20Karlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport23:50Prague AirportPrague Airport - T1/20EconomyA Flight from Lauda Europe goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 18/12/2025 08:20:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 18/12/2025 23:50:00. 50 Economy ticket for £104 per person are available. Travel duration is 15h 30m
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Skyscanner6h 30m015:05Karlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport21:35Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 18/12/2025 15:05:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 18/12/2025 21:35:00. 50 Economy ticket for £205 per person are available. Travel duration is 6h 30m
Cheapest Buses Thursday
Cheapest Flights Thursday
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FlixBus10h 50m003:05KarlsruheCentral Station13:55PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 19/12/2025 03:05:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 19/12/2025 13:55:00. 50 Economy ticket for £55 per person are available. Travel duration is 10h 50m
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FlixBus11h 0m003:05KarlsruheCentral Station14:05PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 19/12/2025 03:05:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 19/12/2025 14:05:00. 50 Economy ticket for £55 per person are available. Travel duration is 11h 0m
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FlixBus10h 25m004:55KarlsruheCentral Station15:20PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 19/12/2025 04:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 19/12/2025 15:20:00. 50 Economy ticket for £58 per person are available. Travel duration is 10h 25m
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FlixBus11h 0m016:15KarlsruheCentral Station03:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 19/12/2025 16:15:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 20/12/2025 03:15:00. 50 Economy ticket for £60 per person are available. Travel duration is 11h 0m
Cheapest Buses Friday
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FlixBus11h 5m013:20KarlsruheCentral Station00:25PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 20/12/2025 13:20:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 21/12/2025 00:25:00. 50 Economy ticket for £55 per person are available. Travel duration is 11h 5m
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FlixBus11h 0m016:15KarlsruheCentral Station03:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 20/12/2025 16:15:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 21/12/2025 03:15:00. 50 Economy ticket for £55 per person are available. Travel duration is 11h 0m
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FlixBus10h 50m003:05KarlsruheCentral Station13:55PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 20/12/2025 03:05:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 20/12/2025 13:55:00. 50 Economy ticket for £63 per person are available. Travel duration is 10h 50m
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FlixBus11h 0m003:05KarlsruheCentral Station14:05PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 20/12/2025 03:05:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 20/12/2025 14:05:00. 50 Economy ticket for £63 per person are available. Travel duration is 11h 0m
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LC Perú6h 15m018:45Karlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport01:00Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 20/12/2025 18:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 21/12/2025 01:00:00. 50 Economy ticket for £192 per person are available. Travel duration is 6h 15m
Cheapest Buses Saturday
Cheapest Flights Saturday
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FlixBus9h 0m006:25KarlsruheCentral Station15:25PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 21/12/2025 06:25:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 21/12/2025 15:25:00. 50 Economy ticket for £54 per person are available. Travel duration is 9h 0m
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FlixBus9h 45m006:25KarlsruheCentral Station16:10PragueČerný Most0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 21/12/2025 06:25:00 to Černý Most, Prague (Czech Republic) arriving at 21/12/2025 16:10:00. 50 Economy ticket for £54 per person are available. Travel duration is 9h 45m
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FlixBus8h 30m013:20KarlsruheCentral Station21:50PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 21/12/2025 13:20:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 21/12/2025 21:50:00. 50 Economy ticket for £56 per person are available. Travel duration is 8h 30m
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FlixBus10h 50m003:05KarlsruheCentral Station13:55PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 21/12/2025 03:05:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 21/12/2025 13:55:00. 50 Economy ticket for £61 per person are available. Travel duration is 10h 50m
Cheapest Buses Sunday
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FlixBus11h 40m018:20KarlsruheCentral Station06:00PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 22/12/2025 18:20:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 23/12/2025 06:00:00. 50 Economy ticket for £46 per person are available. Travel duration is 11h 40m
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FlixBus9h 35m013:20KarlsruheCentral Station22:55PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 22/12/2025 13:20:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 22/12/2025 22:55:00. 50 Economy ticket for £46 per person are available. Travel duration is 9h 35m
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FlixBus10h 25m004:55KarlsruheCentral Station15:20PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 22/12/2025 04:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 22/12/2025 15:20:00. 50 Economy ticket for £47 per person are available. Travel duration is 10h 25m
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FlixBus10h 30m011:45KarlsruheCentral Station22:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 22/12/2025 11:45:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 22/12/2025 22:15:00. 50 Economy ticket for £47 per person are available. Travel duration is 10h 30m
Cheapest Buses Monday
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FlixBus10h 30m000:05KarlsruheCentral Station10:35PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 23/12/2025 00:05:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 23/12/2025 10:35:00. 50 Economy ticket for £45 per person are available. Travel duration is 10h 30m
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FlixBus10h 25m004:55KarlsruheCentral Station15:20PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 23/12/2025 04:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 23/12/2025 15:20:00. 50 Economy ticket for £45 per person are available. Travel duration is 10h 25m
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FlixBus11h 5m013:20KarlsruheCentral Station00:25PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 23/12/2025 13:20:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 24/12/2025 00:25:00. 50 Economy ticket for £45 per person are available. Travel duration is 11h 5m
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FlixBus10h 40m000:05KarlsruheCentral Station10:45PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 23/12/2025 00:05:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 23/12/2025 10:45:00. 50 Economy ticket for £45 per person are available. Travel duration is 10h 40m
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Skyscanner5h 50m018:20Karlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport00:10Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 23/12/2025 18:20:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 24/12/2025 00:10:00. 50 Economy ticket for £184 per person are available. Travel duration is 5h 50m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
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FlixBus8h 55m008:35KarlsruheCentral Station17:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 24/12/2025 08:35:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 24/12/2025 17:30:00. 50 Economy ticket for £46 per person are available. Travel duration is 8h 55m
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FlixBus9h 10m008:35KarlsruheCentral Station17:45PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 24/12/2025 08:35:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 24/12/2025 17:45:00. 50 Economy ticket for £46 per person are available. Travel duration is 9h 10m
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FlixBus8h 30m013:20KarlsruheCentral Station21:50PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 24/12/2025 13:20:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 24/12/2025 21:50:00. 50 Economy ticket for £48 per person are available. Travel duration is 8h 30m
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FlixBus10h 30m011:45KarlsruheCentral Station22:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 24/12/2025 11:45:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 24/12/2025 22:15:00. 50 Economy ticket for £53 per person are available. Travel duration is 10h 30m
Cheapest Buses Wednesday
What are the fastest trips from Karlsruhe to Prague?
You can get to Prague from Karlsruhe in just 5h 50m with a Flight from Skyscanner. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Skyscanner6h 30m015:05Karlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport21:35Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 18/12/2025 15:05:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 18/12/2025 21:35:00. 50 Economy ticket for £205 per person are available. Travel duration is 6h 30m
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Lauda Europe15h 30m008:20Karlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport23:50Prague AirportPrague Airport - T1/20EconomyA Flight from Lauda Europe goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 18/12/2025 08:20:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 18/12/2025 23:50:00. 50 Economy ticket for £104 per person are available. Travel duration is 15h 30m
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FlixBus8h 55m008:35KarlsruheCentral Station17:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 18/12/2025 08:35:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 18/12/2025 17:30:00. 50 Economy ticket for £46 per person are available. Travel duration is 8h 55m
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FlixBus9h 0m006:25KarlsruheCentral Station15:25PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 18/12/2025 06:25:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 18/12/2025 15:25:00. 50 Economy ticket for £48 per person are available. Travel duration is 9h 0m
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FlixBus9h 10m008:35KarlsruheCentral Station17:45PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 18/12/2025 08:35:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 18/12/2025 17:45:00. 50 Economy ticket for £46 per person are available. Travel duration is 9h 10m
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FlixBus10h 25m004:55KarlsruheCentral Station15:20PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 18/12/2025 04:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 18/12/2025 15:20:00. 50 Economy ticket for £48 per person are available. Travel duration is 10h 25m
Fastest Flights Thursday
Fastest Buses Thursday
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FlixBus8h 55m008:35KarlsruheCentral Station17:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 19/12/2025 08:35:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 19/12/2025 17:30:00. 50 Economy ticket for £63 per person are available. Travel duration is 8h 55m
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FlixBus10h 25m004:55KarlsruheCentral Station15:20PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 19/12/2025 04:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 19/12/2025 15:20:00. 50 Economy ticket for £58 per person are available. Travel duration is 10h 25m
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FlixBus10h 50m003:05KarlsruheCentral Station13:55PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 19/12/2025 03:05:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 19/12/2025 13:55:00. 50 Economy ticket for £55 per person are available. Travel duration is 10h 50m
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FlixBus11h 0m003:05KarlsruheCentral Station14:05PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 19/12/2025 03:05:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 19/12/2025 14:05:00. 50 Economy ticket for £55 per person are available. Travel duration is 11h 0m
Fastest Buses Friday
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LC Perú6h 15m018:45Karlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport01:00Prague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 20/12/2025 18:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 21/12/2025 01:00:00. 50 Economy ticket for £192 per person are available. Travel duration is 6h 15m
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FlixBus10h 25m004:55KarlsruheCentral Station15:20PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 20/12/2025 04:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 20/12/2025 15:20:00. 50 Economy ticket for £65 per person are available. Travel duration is 10h 25m
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FlixBus10h 50m003:05KarlsruheCentral Station13:55PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 20/12/2025 03:05:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 20/12/2025 13:55:00. 50 Economy ticket for £63 per person are available. Travel duration is 10h 50m
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FlixBus11h 0m016:15KarlsruheCentral Station03:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 20/12/2025 16:15:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 21/12/2025 03:15:00. 50 Economy ticket for £55 per person are available. Travel duration is 11h 0m
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FlixBus11h 0m003:05KarlsruheCentral Station14:05PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 20/12/2025 03:05:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 20/12/2025 14:05:00. 50 Economy ticket for £63 per person are available. Travel duration is 11h 0m
Fastest Flights Saturday
Fastest Buses Saturday
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FlixBus8h 30m013:20KarlsruheCentral Station21:50PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 21/12/2025 13:20:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 21/12/2025 21:50:00. 50 Economy ticket for £56 per person are available. Travel duration is 8h 30m
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FlixBus9h 0m006:25KarlsruheCentral Station15:25PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 21/12/2025 06:25:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 21/12/2025 15:25:00. 50 Economy ticket for £54 per person are available. Travel duration is 9h 0m
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FlixBus9h 45m006:25KarlsruheCentral Station16:10PragueČerný Most0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 21/12/2025 06:25:00 to Černý Most, Prague (Czech Republic) arriving at 21/12/2025 16:10:00. 50 Economy ticket for £54 per person are available. Travel duration is 9h 45m
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FlixBus10h 25m004:55KarlsruheCentral Station15:20PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 21/12/2025 04:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 21/12/2025 15:20:00. 50 Economy ticket for £61 per person are available. Travel duration is 10h 25m
Fastest Buses Sunday
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FlixBus9h 35m013:20KarlsruheCentral Station22:55PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 22/12/2025 13:20:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 22/12/2025 22:55:00. 50 Economy ticket for £46 per person are available. Travel duration is 9h 35m
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FlixBus10h 25m004:55KarlsruheCentral Station15:20PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 22/12/2025 04:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 22/12/2025 15:20:00. 50 Economy ticket for £47 per person are available. Travel duration is 10h 25m
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FlixBus10h 30m011:45KarlsruheCentral Station22:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 22/12/2025 11:45:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 22/12/2025 22:15:00. 50 Economy ticket for £47 per person are available. Travel duration is 10h 30m
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FlixBus11h 5m013:20KarlsruheCentral Station00:25PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 22/12/2025 13:20:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 23/12/2025 00:25:00. 50 Economy ticket for £47 per person are available. Travel duration is 11h 5m
Fastest Buses Monday
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Skyscanner5h 50m018:20Karlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport00:10Prague AirportPrague Airport - T1/20EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 23/12/2025 18:20:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 24/12/2025 00:10:00. 50 Economy ticket for £184 per person are available. Travel duration is 5h 50m
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FlixBus8h 55m012:15KarlsruheCentral Station21:10PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 23/12/2025 12:15:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 23/12/2025 21:10:00. 50 Economy ticket for £45 per person are available. Travel duration is 8h 55m
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FlixBus10h 25m004:55KarlsruheCentral Station15:20PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 23/12/2025 04:55:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 23/12/2025 15:20:00. 50 Economy ticket for £45 per person are available. Travel duration is 10h 25m
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FlixBus10h 30m000:05KarlsruheCentral Station10:35PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 23/12/2025 00:05:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 23/12/2025 10:35:00. 50 Economy ticket for £45 per person are available. Travel duration is 10h 30m
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FlixBus10h 40m000:05KarlsruheCentral Station10:45PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 23/12/2025 00:05:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 23/12/2025 10:45:00. 50 Economy ticket for £45 per person are available. Travel duration is 10h 40m
Fastest Flights Tuesday
Fastest Buses Tuesday
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FlixBus8h 30m013:20KarlsruheCentral Station21:50PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 24/12/2025 13:20:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 24/12/2025 21:50:00. 50 Economy ticket for £48 per person are available. Travel duration is 8h 30m
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FlixBus8h 55m008:35KarlsruheCentral Station17:30PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 24/12/2025 08:35:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 24/12/2025 17:30:00. 50 Economy ticket for £46 per person are available. Travel duration is 8h 55m
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FlixBus9h 10m008:35KarlsruheCentral Station17:45PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 24/12/2025 08:35:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 24/12/2025 17:45:00. 50 Economy ticket for £46 per person are available. Travel duration is 9h 10m
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FlixBus10h 30m011:45KarlsruheCentral Station22:15PragueWilsonova Coach Station0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 24/12/2025 11:45:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 24/12/2025 22:15:00. 50 Economy ticket for £53 per person are available. Travel duration is 10h 30m
Fastest Buses Wednesday
Here you will find all operators and timetables for a
Bus from Karlsruhe to Prague
What are the most popular stations in Karlsruhe and Prague?
In Karlsruhe, you will usually depart from Central Station, Heidehof Train Station or Tullastraße / Verkehrsbetriebe Train Station, while in Prague you will be arriving at Wilsonova Coach Station, ÚAN Florenc or Černý Most, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Prague from Karlsruhe? With 5 connections between 1 Bus, Flight and Carpool operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Karlsruhe and Prague, you can pay as low as £45 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Skyscanner: you will get to Prague in just 5h 50m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Karlsruhe and Prague are FlixBus, Skyscanner and Lauda Europe, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Karlsruhe and Prague is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Ettlingen or to Horoměřice, and look at flights from Karlsruhe/Baden-Baden Airport, and landing at Prague Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Karlsruhe to Prague?
The most popular companies between Karlsruhe and Prague, are FlixBus, Skyscanner and Lauda Europe. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus
Airlines: Skyscanner, Lauda Europe and LC Perú
All you need to know when you travel from Karlsruhe to Prague
Check all information on comfort and services on all modes of transports from Karlsruhe to Prague. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Karlsruhe to Prague
How can I reach Prague from Karlsruhe?
Every day, there are on average 5 connections between Bus, Flight and Carpool, with which you can get to Prague from Karlsruhe.
How far is Prague from Karlsruhe?
The distance between Karlsruhe and Prague is 451.2 km.
What is the most ecofriendly mode of transport between Karlsruhe and Prague?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 12 kgs of CO2, a train 16 kgs, a car 77 kgs, and a flight 111 kgs.
What is the cheapest mode of transport from Karlsruhe to Prague?
You can get to Prague with just £45 by taking a Bus from FlixBus.
What is the fastest way to get from Karlsruhe to Prague?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Prague in just 5h 50m with a Flight from Skyscanner.
More routes to Karlsruhe and to Prague
Looking for more options? Here you can see the most popular routes to Karlsruhe and to Prague. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Karlsruhe
- Barcelona to Karlsruhe
- Berlin to Karlsruhe
- Bremen to Karlsruhe
- Dortmund to Karlsruhe
- Dresden to Karlsruhe
- Dusseldorf to Karlsruhe
- Frankfurt am Main Airport to Karlsruhe
- Frankfurt am Main to Karlsruhe
- Frankfurt Hahn Airport to Karlsruhe
- Freiburg to Karlsruhe
- Hamburg to Karlsruhe
- Heidelberg to Karlsruhe
- Innsbruck to Karlsruhe
- Mannheim to Karlsruhe
- Memmingen Airport to Karlsruhe
- Milan to Karlsruhe
- Munich to Karlsruhe
- Nuremberg to Karlsruhe
- Paris to Karlsruhe
- Saarbruecken to Karlsruhe
- Strasbourg to Karlsruhe
- Stuttgart Airport to Karlsruhe
- Stuttgart to Karlsruhe
- Vienna to Karlsruhe
- Trips to Prague
- Amsterdam to Prague
- Berlin to Prague
- Brno to Prague
- Budapest to Prague
- Dresden Airport to Prague
- Dresden to Prague
- Florence to Prague
- Humpolec to Prague
- Karlovy Vary to Prague
- Krakow to Prague
- Leipzig to Prague
- Linz to Prague
- London to Prague
- Lyon to Prague
- Memmingen to Prague
- Milan to Prague
- Minsk to Prague
- Munich to Prague
- Nuremberg to Prague
- Pelhřimov to Prague
- Třebíč to Prague
- Vienna to Prague
- Vrútky to Prague
- Zurich to Prague

