What is the best way to travel from Harrisburg, PA to Columbus, OH?
Looking for a trip? Check and compare all the available Buses and Flights to Columbus, OH from Harrisburg, PA. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Columbus, OH from Harrisburg, PA?
You can reach Columbus, OH with just £42 by taking a Bus from Greyhound US, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Greyhound US8h 40m013:20Harrisburg, PABus Station22:00Columbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 05/12/2025 13:20:00 to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 05/12/2025 22:00:00. 50 Economy ticket for £43 per person are available. Travel duration is 8h 40m
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Greyhound US9h 0m019:45Harrisburg, PABus Station04:45Columbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 05/12/2025 19:45:00 to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 06/12/2025 04:45:00. 50 Economy ticket for £43 per person are available. Travel duration is 9h 0m
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FlixBus8h 40m014:40Harrisburg, PABus Station23:20Columbus, OHABM Public Parking0EconomyA Bus from FlixBus goes from Bus Station, Harrisburg, PA (USA) at 05/12/2025 14:40:00 to ABM Public Parking, Columbus, OH (USA) arriving at 05/12/2025 23:20:00. 50 Economy ticket for £43 per person are available. Travel duration is 8h 40m
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Greyhound US11h 55m002:30Harrisburg, PABus Station14:25Columbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 05/12/2025 02:30:00 to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 05/12/2025 14:25:00. 50 Economy ticket for £59 per person are available. Travel duration is 11h 55m
Cheapest Buses Friday
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Greyhound US8h 40m013:20Harrisburg, PABus Station22:00Columbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 06/12/2025 13:20:00 to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 06/12/2025 22:00:00. 50 Economy ticket for £43 per person are available. Travel duration is 8h 40m
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Greyhound US9h 0m019:45Harrisburg, PABus Station04:45Columbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 06/12/2025 19:45:00 to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 07/12/2025 04:45:00. 50 Economy ticket for £43 per person are available. Travel duration is 9h 0m
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FlixBus8h 40m014:40Harrisburg, PABus Station23:20Columbus, OHABM Public Parking0EconomyA Bus from FlixBus goes from Bus Station, Harrisburg, PA (USA) at 06/12/2025 14:40:00 to ABM Public Parking, Columbus, OH (USA) arriving at 06/12/2025 23:20:00. 50 Economy ticket for £43 per person are available. Travel duration is 8h 40m
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Greyhound US8h 30m020:15Harrisburg, PABus Station04:45Columbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 06/12/2025 20:15:00 to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 07/12/2025 04:45:00. 50 Economy ticket for £52 per person are available. Travel duration is 8h 30m
Cheapest Buses Saturday
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Greyhound US8h 40m013:20Harrisburg, PABus Station22:00Columbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 08/12/2025 13:20:00 to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 08/12/2025 22:00:00. 50 Economy ticket for £42 per person are available. Travel duration is 8h 40m
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Greyhound US9h 0m019:45Harrisburg, PABus Station04:45Columbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 08/12/2025 19:45:00 to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 09/12/2025 04:45:00. 50 Economy ticket for £42 per person are available. Travel duration is 9h 0m
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Greyhound US7h 55m014:05Harrisburg, PABus Station22:00Columbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 08/12/2025 14:05:00 to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 08/12/2025 22:00:00. 50 Economy ticket for £58 per person are available. Travel duration is 7h 55m
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Greyhound US8h 30m020:15Harrisburg, PABus Station04:45Columbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 08/12/2025 20:15:00 to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 09/12/2025 04:45:00. 50 Economy ticket for £58 per person are available. Travel duration is 8h 30m
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Greyhound US11h 55m002:30Harrisburg, PABus Station14:25Columbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 08/12/2025 02:30:00 to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 08/12/2025 14:25:00. 50 Economy ticket for £65 per person are available. Travel duration is 11h 55m
Cheapest Buses Monday
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Greyhound US9h 0m019:45Harrisburg, PABus Station04:45Columbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 10/12/2025 19:45:00 to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 11/12/2025 04:45:00. 50 Economy ticket for £42 per person are available. Travel duration is 9h 0m
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Greyhound US8h 40m013:20Harrisburg, PABus Station22:00Columbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 10/12/2025 13:20:00 to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 10/12/2025 22:00:00. 50 Economy ticket for £44 per person are available. Travel duration is 8h 40m
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FlixBus8h 40m014:40Harrisburg, PABus Station23:20Columbus, OHABM Public Parking0EconomyA Bus from FlixBus goes from Bus Station, Harrisburg, PA (USA) at 10/12/2025 14:40:00 to ABM Public Parking, Columbus, OH (USA) arriving at 10/12/2025 23:20:00. 50 Economy ticket for £44 per person are available. Travel duration is 8h 40m
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Greyhound US7h 55m014:05Harrisburg, PABus Station22:00Columbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 10/12/2025 14:05:00 to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 10/12/2025 22:00:00. 50 Economy ticket for £55 per person are available. Travel duration is 7h 55m
Cheapest Buses Wednesday
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Greyhound US8h 55m014:50Harrisburg, PABus Station23:45Columbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 11/12/2025 14:50:00 to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 11/12/2025 23:45:00. 50 Economy ticket for £44 per person are available. Travel duration is 8h 55m
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Greyhound US9h 0m019:45Harrisburg, PABus Station04:45Columbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 11/12/2025 19:45:00 to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 12/12/2025 04:45:00. 50 Economy ticket for £44 per person are available. Travel duration is 9h 0m
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FlixBus8h 40m014:40Harrisburg, PABus Station23:20Columbus, OHABM Public Parking0EconomyA Bus from FlixBus goes from Bus Station, Harrisburg, PA (USA) at 11/12/2025 14:40:00 to ABM Public Parking, Columbus, OH (USA) arriving at 11/12/2025 23:20:00. 50 Economy ticket for £44 per person are available. Travel duration is 8h 40m
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Greyhound US8h 30m020:15Harrisburg, PABus Station04:45Columbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 11/12/2025 20:15:00 to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 12/12/2025 04:45:00. 50 Economy ticket for £54 per person are available. Travel duration is 8h 30m
Cheapest Buses Thursday
What are the fastest trips from Harrisburg, PA to Columbus, OH?
You can get to Columbus, OH from Harrisburg, PA in just 7h 55m with a Bus from Greyhound US. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Greyhound US8h 40m013:20Harrisburg, PABus Station22:00Columbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 05/12/2025 13:20:00 to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 05/12/2025 22:00:00. 50 Economy ticket for £43 per person are available. Travel duration is 8h 40m
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FlixBus8h 40m014:40Harrisburg, PABus Station23:20Columbus, OHABM Public Parking0EconomyA Bus from FlixBus goes from Bus Station, Harrisburg, PA (USA) at 05/12/2025 14:40:00 to ABM Public Parking, Columbus, OH (USA) arriving at 05/12/2025 23:20:00. 50 Economy ticket for £43 per person are available. Travel duration is 8h 40m
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Greyhound US9h 0m019:45Harrisburg, PABus Station04:45Columbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 05/12/2025 19:45:00 to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 06/12/2025 04:45:00. 50 Economy ticket for £43 per person are available. Travel duration is 9h 0m
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Greyhound US11h 55m002:30Harrisburg, PABus Station14:25Columbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 05/12/2025 02:30:00 to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 05/12/2025 14:25:00. 50 Economy ticket for £59 per person are available. Travel duration is 11h 55m
Fastest Buses Friday
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Greyhound US8h 30m020:15Harrisburg, PABus Station04:45Columbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 06/12/2025 20:15:00 to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 07/12/2025 04:45:00. 50 Economy ticket for £52 per person are available. Travel duration is 8h 30m
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Greyhound US8h 40m013:20Harrisburg, PABus Station22:00Columbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 06/12/2025 13:20:00 to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 06/12/2025 22:00:00. 50 Economy ticket for £43 per person are available. Travel duration is 8h 40m
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FlixBus8h 40m014:40Harrisburg, PABus Station23:20Columbus, OHABM Public Parking0EconomyA Bus from FlixBus goes from Bus Station, Harrisburg, PA (USA) at 06/12/2025 14:40:00 to ABM Public Parking, Columbus, OH (USA) arriving at 06/12/2025 23:20:00. 50 Economy ticket for £43 per person are available. Travel duration is 8h 40m
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Greyhound US9h 0m019:45Harrisburg, PABus Station04:45Columbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 06/12/2025 19:45:00 to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 07/12/2025 04:45:00. 50 Economy ticket for £43 per person are available. Travel duration is 9h 0m
Fastest Buses Saturday
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Greyhound US7h 55m014:05Harrisburg, PABus Station22:00Columbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 08/12/2025 14:05:00 to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 08/12/2025 22:00:00. 50 Economy ticket for £58 per person are available. Travel duration is 7h 55m
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Greyhound US8h 30m020:15Harrisburg, PABus Station04:45Columbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 08/12/2025 20:15:00 to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 09/12/2025 04:45:00. 50 Economy ticket for £58 per person are available. Travel duration is 8h 30m
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Greyhound US8h 40m013:20Harrisburg, PABus Station22:00Columbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 08/12/2025 13:20:00 to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 08/12/2025 22:00:00. 50 Economy ticket for £42 per person are available. Travel duration is 8h 40m
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Greyhound US9h 0m019:45Harrisburg, PABus Station04:45Columbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 08/12/2025 19:45:00 to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 09/12/2025 04:45:00. 50 Economy ticket for £42 per person are available. Travel duration is 9h 0m
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Greyhound US11h 55m002:30Harrisburg, PABus Station14:25Columbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 08/12/2025 02:30:00 to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 08/12/2025 14:25:00. 50 Economy ticket for £65 per person are available. Travel duration is 11h 55m
Fastest Buses Monday
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Greyhound US7h 55m014:05Harrisburg, PABus Station22:00Columbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 10/12/2025 14:05:00 to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 10/12/2025 22:00:00. 50 Economy ticket for £55 per person are available. Travel duration is 7h 55m
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Greyhound US8h 40m013:20Harrisburg, PABus Station22:00Columbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 10/12/2025 13:20:00 to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 10/12/2025 22:00:00. 50 Economy ticket for £44 per person are available. Travel duration is 8h 40m
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FlixBus8h 40m014:40Harrisburg, PABus Station23:20Columbus, OHABM Public Parking0EconomyA Bus from FlixBus goes from Bus Station, Harrisburg, PA (USA) at 10/12/2025 14:40:00 to ABM Public Parking, Columbus, OH (USA) arriving at 10/12/2025 23:20:00. 50 Economy ticket for £44 per person are available. Travel duration is 8h 40m
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Greyhound US9h 0m019:45Harrisburg, PABus Station04:45Columbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 10/12/2025 19:45:00 to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 11/12/2025 04:45:00. 50 Economy ticket for £42 per person are available. Travel duration is 9h 0m
Fastest Buses Wednesday
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Greyhound US8h 30m020:15Harrisburg, PABus Station04:45Columbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 11/12/2025 20:15:00 to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 12/12/2025 04:45:00. 50 Economy ticket for £54 per person are available. Travel duration is 8h 30m
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FlixBus8h 40m014:40Harrisburg, PABus Station23:20Columbus, OHABM Public Parking0EconomyA Bus from FlixBus goes from Bus Station, Harrisburg, PA (USA) at 11/12/2025 14:40:00 to ABM Public Parking, Columbus, OH (USA) arriving at 11/12/2025 23:20:00. 50 Economy ticket for £44 per person are available. Travel duration is 8h 40m
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Greyhound US8h 55m014:50Harrisburg, PABus Station23:45Columbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 11/12/2025 14:50:00 to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 11/12/2025 23:45:00. 50 Economy ticket for £44 per person are available. Travel duration is 8h 55m
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Greyhound US9h 0m019:45Harrisburg, PABus Station04:45Columbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Station, Harrisburg, PA (USA) at 11/12/2025 19:45:00 to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 12/12/2025 04:45:00. 50 Economy ticket for £44 per person are available. Travel duration is 9h 0m
Fastest Buses Thursday
Here you will find all operators and timetables for a
Bus from Harrisburg, PA to Columbus, OH
What are the most popular stations in Harrisburg, PA and Columbus, OH?
In Harrisburg, PA, you will usually depart from Bus Station, Mall Parking Lot or Central Station, while in Columbus, OH you will be arriving at E Main St & S Lazelle St, ABM Public Parking or Greyhound Bus Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Columbus, OH from Harrisburg, PA? With 4 connections between 2 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Harrisburg, PA and Columbus, OH, you can pay as low as £42 with a Bus from Greyhound US.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Bus from Greyhound US: you will get to Columbus, OH in just 7h 55m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Harrisburg, PA and Columbus, OH are Greyhound US and FlixBus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Harrisburg, PA and Columbus, OH is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from New Cumberland, PA or to Upper Arlington, OH, and look at flights from , and landing at Columbus Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Harrisburg, PA to Columbus, OH?
The most popular companies between Harrisburg, PA and Columbus, OH, are Greyhound US and FlixBus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Greyhound US and FlixBus
All you need to know when you travel from Harrisburg, PA to Columbus, OH
Check all information on comfort and services on all modes of transports from Harrisburg, PA to Columbus, OH. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Harrisburg, PA to Columbus, OH
How can I reach Columbus, OH from Harrisburg, PA?
Every day, there are on average 4 connections between Bus and Flight, with which you can get to Columbus, OH from Harrisburg, PA.
How far is Columbus, OH from Harrisburg, PA?
The distance between Harrisburg, PA and Columbus, OH is 525.1 km.
What is the most ecofriendly mode of transport between Harrisburg, PA and Columbus, OH?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 14 kgs of CO2, a train 18 kgs, a car 89 kgs, and a flight 129 kgs.
What is the cheapest mode of transport from Harrisburg, PA to Columbus, OH?
You can get to Columbus, OH with just £42 by taking a Bus from Greyhound US.
What is the fastest way to get from Harrisburg, PA to Columbus, OH?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Columbus, OH in just 7h 55m with a Bus from Greyhound US.
More routes to Harrisburg, PA and to Columbus, OH
Looking for more options? Here you can see the most popular routes to Harrisburg, PA and to Columbus, OH. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Harrisburg, PA
- Orlando, FL to Harrisburg, PA
- Trips to Columbus, OH
- Chicago to Columbus, OH
- New York to Columbus, OH
- San Diego to Columbus, OH

